Click here to switch to the map view.

The map label for this gene is fabF [C]

Identifier: 238027282

GI number: 238027282

Start: 1837176

End: 1838441

Strand: Direct

Name: fabF [C]

Synonym: bglu_1g16690

Alternate gene names: 238027282

Gene position: 1837176-1838441 (Clockwise)

Preceding gene: 238027281

Following gene: 238027283

Centisome position: 47.03

GC content: 78.04

Gene sequence:

>1266_bases
ATGAGCCCGCCGATCGCGATCACCGGGATCGGCCTGATCTCGCCGGCCGGCTCCACGCCCGCCGCGCTGTGGGCCGCGCT
GGCCGGGCGCGCCGAGCTGCGCGGCCCCTGGCCGAAGCGCTCGCTCGCGGCCTATCCGGTCGACAACTGCGTGGCGATCC
CCGAGGCCCAGTGGCGCGCGCTCGATGTGGCGCGCGGCGGCGTCGAGAACCGCGCCGCGGCGCTGGCGCGCTTCGCCGTG
GAGCGCTGCCTGGAGGCGGCGGGGCTGGCCCACGGCGGGCCGGCCGAGCCGGCTGCGGGCGCCGCGCCGGCCGGGATGCG
GATCGGCTGCGTGCTCGGCACCACCACCGCCGGCGTCGAGGTGGCCGAGAACGCGCTGCTGGGCCGCCATGGCGGCGAGG
CGGCCGGCGTGGCCGAGTTCGACGCGAGCCGGCTTCTGCCCGGCGACGCCGCGCGCTGGCAGGGGCCGCTTGCCGTGCTG
TCCACGGCCTGCTCGTCGGGGCTGCTCGCGCCGTCGCTGGCGATCGACGCGCTGCTGGCGGGCGAGGCCGATGCGATGGT
GGCCGGCGGCGTGGACGTGCTGCTCGAATACACGGTGTGCGGCTTCAACGGCCTGCGCGTGGCCACCCGCGACGCCTGCC
GGCCGTTCGACGCGAGCCGGCAGGGCGTGGTGCTCTCGGAGGGCGCGGCCTGCGTCTGCCTGGAGCGGCTCGACGCGGCG
CTGGCGCGGCGCGCCACGATCCACGCGGTGGTGAGCGCGCGCGCGGCCGGCTGTGACGCCGCGCATGCCACCGCGCCCGA
CATCGAGGGCGTGGCGCGCACGCTGATCGCGGCGCTGACCGCGCCGGCCGCGCATGGCGGGCGTGCCGCGCGGCCGGCCG
GCGTGTTCGCGCACGGCACCGGCACGCCGACCAACGACATCGCCGAGATCACCGCGCTGCGCGCCGCCTTCGCGGCCGCG
TTCGGCAGCGACGCGCTGCCGCCCGTCACCTCGATCAAGGCCACGCTCGGCCATCCGCAGGCGGCGGCCGGGGCCTTCTC
GCTCGCGGCCGCGTGCCTCGCGCTGCGGCATCGGAGCTTGCCGCCCACCGCGAATCTCCAGGCGCGCGACGCCGCGCTCG
GCGACGCGCCGATCGTCGACGGCGCGGGCTGGCCGCTCGAGGGCGCCAGCGTGCTGGTGGACGCGTTCGGCTTCGGCGGC
AACAACTGCGTGATGGTGCTGACCGATCCGGCCGCGCTGCACGAGCTCGAGGAGGGCGCGGCATGA

Upstream 100 bases:

>100_bases
CGCGCTACGCGATCGAACTGCCGGCCGGCTCGCTGGCGCAACTGACGCTGGCCTCGCTGGCCGAGGCCGTGGTCGCCGCC
GCGCAGCGGGAGGCCGCCGC

Downstream 100 bases:

>100_bases
GCCACCATCCGACAGCCGCGCTGCGCATCGTGGCCACCGCCGGCGCCGCGCCCGACGCGCCCGGCACGCCGGCCGACGCC
TGGCTGCATGCCGAGCGCCG

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: actI ORF1 [H]

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MSPPIAITGIGLISPAGSTPAALWAALAGRAELRGPWPKRSLAAYPVDNCVAIPEAQWRALDVARGGVENRAAALARFAV
ERCLEAAGLAHGGPAEPAAGAAPAGMRIGCVLGTTTAGVEVAENALLGRHGGEAAGVAEFDASRLLPGDAARWQGPLAVL
STACSSGLLAPSLAIDALLAGEADAMVAGGVDVLLEYTVCGFNGLRVATRDACRPFDASRQGVVLSEGAACVCLERLDAA
LARRATIHAVVSARAAGCDAAHATAPDIEGVARTLIAALTAPAAHGGRAARPAGVFAHGTGTPTNDIAEITALRAAFAAA
FGSDALPPVTSIKATLGHPQAAAGAFSLAAACLALRHRSLPPTANLQARDAALGDAPIVDGAGWPLEGASVLVDAFGFGG
NNCVMVLTDPAALHELEEGAA

Sequences:

>Translated_421_residues
MSPPIAITGIGLISPAGSTPAALWAALAGRAELRGPWPKRSLAAYPVDNCVAIPEAQWRALDVARGGVENRAAALARFAV
ERCLEAAGLAHGGPAEPAAGAAPAGMRIGCVLGTTTAGVEVAENALLGRHGGEAAGVAEFDASRLLPGDAARWQGPLAVL
STACSSGLLAPSLAIDALLAGEADAMVAGGVDVLLEYTVCGFNGLRVATRDACRPFDASRQGVVLSEGAACVCLERLDAA
LARRATIHAVVSARAAGCDAAHATAPDIEGVARTLIAALTAPAAHGGRAARPAGVFAHGTGTPTNDIAEITALRAAFAAA
FGSDALPPVTSIKATLGHPQAAAGAFSLAAACLALRHRSLPPTANLQARDAALGDAPIVDGAGWPLEGASVLVDAFGFGG
NNCVMVLTDPAALHELEEGAA
>Mature_420_residues
SPPIAITGIGLISPAGSTPAALWAALAGRAELRGPWPKRSLAAYPVDNCVAIPEAQWRALDVARGGVENRAAALARFAVE
RCLEAAGLAHGGPAEPAAGAAPAGMRIGCVLGTTTAGVEVAENALLGRHGGEAAGVAEFDASRLLPGDAARWQGPLAVLS
TACSSGLLAPSLAIDALLAGEADAMVAGGVDVLLEYTVCGFNGLRVATRDACRPFDASRQGVVLSEGAACVCLERLDAAL
ARRATIHAVVSARAAGCDAAHATAPDIEGVARTLIAALTAPAAHGGRAARPAGVFAHGTGTPTNDIAEITALRAAFAAAF
GSDALPPVTSIKATLGHPQAAAGAFSLAAACLALRHRSLPPTANLQARDAALGDAPIVDGAGWPLEGASVLVDAFGFGGN
NCVMVLTDPAALHELEEGAA

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=435, Percent_Identity=30.5747126436782, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI41872631, Length=269, Percent_Identity=31.2267657992565, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1787337, Length=262, Percent_Identity=35.8778625954198, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788663, Length=264, Percent_Identity=30.3030303030303, Blast_Score=104, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71983541, Length=426, Percent_Identity=26.7605633802817, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71983535, Length=268, Percent_Identity=30.2238805970149, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17550940, Length=271, Percent_Identity=27.3062730627306, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI212642053, Length=265, Percent_Identity=29.811320754717, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=455, Percent_Identity=25.7142857142857, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644341, Length=297, Percent_Identity=32.996632996633, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24581345, Length=264, Percent_Identity=29.9242424242424, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: 2.3.1.-

Molecular weight: Translated: 41832; Mature: 41701

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPPIAITGIGLISPAGSTPAALWAALAGRAELRGPWPKRSLAAYPVDNCVAIPEAQWRA
CCCCEEEEEEEEECCCCCCHHHHHHHHHCCHHCCCCCCCCCEECCCCCCEEECCCCHHHH
LDVARGGVENRAAALARFAVERCLEAAGLAHGGPAEPAAGAAPAGMRIGCVLGTTTAGVE
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHH
VAENALLGRHGGEAAGVAEFDASRLLPGDAARWQGPLAVLSTACSSGLLAPSLAIDALLA
HHHHHHHCCCCCCCCCEECCCHHHCCCCCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHC
GEADAMVAGGVDVLLEYTVCGFNGLRVATRDACRPFDASRQGVVLSEGAACVCLERLDAA
CCCCCEECCCHHHHHHHHHCCCCCCEEEHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHH
LARRATIHAVVSARAAGCDAAHATAPDIEGVARTLIAALTAPAAHGGRAARPAGVFAHGT
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCC
GTPTNDIAEITALRAAFAAAFGSDALPPVTSIKATLGHPQAAAGAFSLAAACLALRHRSL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
PPTANLQARDAALGDAPIVDGAGWPLEGASVLVDAFGFGGNNCVMVLTDPAALHELEEGA
CCCCCCCHHHCCCCCCCEECCCCCCCCCHHHEEEHHCCCCCCEEEEEECHHHHHHHHHCC
A
C
>Mature Secondary Structure 
SPPIAITGIGLISPAGSTPAALWAALAGRAELRGPWPKRSLAAYPVDNCVAIPEAQWRA
CCCEEEEEEEEECCCCCCHHHHHHHHHCCHHCCCCCCCCCEECCCCCCEEECCCCHHHH
LDVARGGVENRAAALARFAVERCLEAAGLAHGGPAEPAAGAAPAGMRIGCVLGTTTAGVE
HHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHH
VAENALLGRHGGEAAGVAEFDASRLLPGDAARWQGPLAVLSTACSSGLLAPSLAIDALLA
HHHHHHHCCCCCCCCCEECCCHHHCCCCCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHC
GEADAMVAGGVDVLLEYTVCGFNGLRVATRDACRPFDASRQGVVLSEGAACVCLERLDAA
CCCCCEECCCHHHHHHHHHCCCCCCEEEHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHH
LARRATIHAVVSARAAGCDAAHATAPDIEGVARTLIAALTAPAAHGGRAARPAGVFAHGT
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCC
GTPTNDIAEITALRAAFAAAFGSDALPPVTSIKATLGHPQAAAGAFSLAAACLALRHRSL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
PPTANLQARDAALGDAPIVDGAGWPLEGASVLVDAFGFGGNNCVMVLTDPAALHELEEGA
CCCCCCCHHHCCCCCCCEECCCCCCCCCHHHEEEHHCCCCCCEEEEEECHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953; 1527048 [H]