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The map label for this gene is gntR [H]

Identifier: 238027269

GI number: 238027269

Start: 1818792

End: 1819850

Strand: Reverse

Name: gntR [H]

Synonym: bglu_1g16560

Alternate gene names: 238027269

Gene position: 1819850-1818792 (Counterclockwise)

Preceding gene: 238027270

Following gene: 238027268

Centisome position: 46.59

GC content: 72.24

Gene sequence:

>1059_bases
ATGGCCGACGTCGCGCGGCTCGCCGGCGTCTCGAAGATGTCGGTGTCGCGCGTGCTGACCGGCCAGCACGTCAGCGACGC
CACGCGCGAGCGCGTGATGGACGCGGTGCGCAGGACGGGCTACGTGGCCGACGCGGTGGCGGGCGCGCTCTCGTCGGGCC
GCAACAACGTGATCGCGGTCCTGGTGCCCTCGCTGTCGAGTTCGAACTTCGCCGACACGGTGCGCGGCATCGACAACGTG
GTCGAGACGCGCAACCTGCGCCTGCTGCTCGCCAACACCGACTACCTCGCCGAACGCGAGGAAGCGCTGATCCGCTCGCT
GCTGAGCCACCAGCCGCGCGGCATCGTGGTGACGGGCGGCCACCACACGCCGCGCGCGCGCACCCTGCTCGAACAGGCCG
GCATTCCGGTGATCGAAACCTGGGAGCTGCCGGAGCAGCCGATCGACCGCGTGGTCGGCTTCTCGAACCGGGACGCCGCG
CAGGCCATGACACGCTATCTGTACCAACGCGGCTATCGCCGGATCGGCTTCATCGGCAGCAGCTCGCTGCTGGACCTGCG
CGGCATCGCGCGGCGCAACGGCTATCTGGCGGCGGTCGAGGAAGCCGGCCGGCACGCGCCGCGCGACGTGGTGCGGCCGA
TGCCCGCCAGCGACATGGCGCACGGCGCCGCGATGGGCCACAGCAGAGCCGCGCTGGGCCAGCTGCTGGCGCAATGGCCC
GACACCGACGCGGTGATGTGCACCAGCGACATCCACGCGTTCGGCGCGATCATGGCCTGCCACCGGCTCGGGCTCACCGT
GCCGGGCGACCTGGCCGTGGCCGGCTTCGGCGACTTCGAGGTGGCGCGCCACTGCTATCCGAGCATCACCACGGTCTCGG
TCGATGCCTACGGGATCGGCCATGCGGCGGGCCGGTCGCTGCTGGCCGCGATCGACGGCTCGGAACGGCCCAGCGCCTCG
CGCCGCGAGATCGCCTCGCAGCGCGCGCAGCGCCAGCAGCACGACGCGCCGCCGCTGATCCGGATTCCCTACGCGGTGGT
CGCGCGCGAGAGCGCATAG

Upstream 100 bases:

>100_bases
GAGCACCGCGCGGCACGCACGCGTCCGATCCGAACCGCCGTTTCCAGAACCGATGAGCGCAAATCACGATTCCCTGCCCG
AGCCGGGCGCGCCGATCCGC

Downstream 100 bases:

>100_bases
GCCCGGCGGCGGCCATGCCGATGCGCCCCGCCCGCCGGTCGCCTTGCCCGGCCGCGCCCTGGCCGCGCGGTCCGGCGTGC
CGCCCGCACCGCTCGCACCG

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MADVARLAGVSKMSVSRVLTGQHVSDATRERVMDAVRRTGYVADAVAGALSSGRNNVIAVLVPSLSSSNFADTVRGIDNV
VETRNLRLLLANTDYLAEREEALIRSLLSHQPRGIVVTGGHHTPRARTLLEQAGIPVIETWELPEQPIDRVVGFSNRDAA
QAMTRYLYQRGYRRIGFIGSSSLLDLRGIARRNGYLAAVEEAGRHAPRDVVRPMPASDMAHGAAMGHSRAALGQLLAQWP
DTDAVMCTSDIHAFGAIMACHRLGLTVPGDLAVAGFGDFEVARHCYPSITTVSVDAYGIGHAAGRSLLAAIDGSERPSAS
RREIASQRAQRQQHDAPPLIRIPYAVVARESA

Sequences:

>Translated_352_residues
MADVARLAGVSKMSVSRVLTGQHVSDATRERVMDAVRRTGYVADAVAGALSSGRNNVIAVLVPSLSSSNFADTVRGIDNV
VETRNLRLLLANTDYLAEREEALIRSLLSHQPRGIVVTGGHHTPRARTLLEQAGIPVIETWELPEQPIDRVVGFSNRDAA
QAMTRYLYQRGYRRIGFIGSSSLLDLRGIARRNGYLAAVEEAGRHAPRDVVRPMPASDMAHGAAMGHSRAALGQLLAQWP
DTDAVMCTSDIHAFGAIMACHRLGLTVPGDLAVAGFGDFEVARHCYPSITTVSVDAYGIGHAAGRSLLAAIDGSERPSAS
RREIASQRAQRQQHDAPPLIRIPYAVVARESA
>Mature_351_residues
ADVARLAGVSKMSVSRVLTGQHVSDATRERVMDAVRRTGYVADAVAGALSSGRNNVIAVLVPSLSSSNFADTVRGIDNVV
ETRNLRLLLANTDYLAEREEALIRSLLSHQPRGIVVTGGHHTPRARTLLEQAGIPVIETWELPEQPIDRVVGFSNRDAAQ
AMTRYLYQRGYRRIGFIGSSSLLDLRGIARRNGYLAAVEEAGRHAPRDVVRPMPASDMAHGAAMGHSRAALGQLLAQWPD
TDAVMCTSDIHAFGAIMACHRLGLTVPGDLAVAGFGDFEVARHCYPSITTVSVDAYGIGHAAGRSLLAAIDGSERPSASR
REIASQRAQRQQHDAPPLIRIPYAVVARESA

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=316, Percent_Identity=35.126582278481, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1790715, Length=317, Percent_Identity=31.5457413249211, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790369, Length=325, Percent_Identity=30.7692307692308, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788474, Length=324, Percent_Identity=31.1728395061728, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787948, Length=324, Percent_Identity=28.0864197530864, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789202, Length=296, Percent_Identity=30.7432432432432, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790194, Length=296, Percent_Identity=26.6891891891892, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1786268, Length=334, Percent_Identity=25.1497005988024, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789068, Length=308, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787906, Length=295, Percent_Identity=28.135593220339, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787580, Length=323, Percent_Identity=24.7678018575851, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786540, Length=317, Percent_Identity=24.2902208201893, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37867; Mature: 37735

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVARLAGVSKMSVSRVLTGQHVSDATRERVMDAVRRTGYVADAVAGALSSGRNNVIAV
CCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEE
LVPSLSSSNFADTVRGIDNVVETRNLRLLLANTDYLAEREEALIRSLLSHQPRGIVVTGG
EECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECC
HHTPRARTLLEQAGIPVIETWELPEQPIDRVVGFSNRDAAQAMTRYLYQRGYRRIGFIGS
CCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCC
SSLLDLRGIARRNGYLAAVEEAGRHAPRDVVRPMPASDMAHGAAMGHSRAALGQLLAQWP
CCHHHHHHHHHCCCCEEEHHHHCCCCCHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCC
DTDAVMCTSDIHAFGAIMACHRLGLTVPGDLAVAGFGDFEVARHCYPSITTVSVDAYGIG
CCCEEEECHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCCC
HAAGRSLLAAIDGSERPSASRREIASQRAQRQQHDAPPLIRIPYAVVARESA
HHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCHHHEEECCC
>Mature Secondary Structure 
ADVARLAGVSKMSVSRVLTGQHVSDATRERVMDAVRRTGYVADAVAGALSSGRNNVIAV
CCHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEE
LVPSLSSSNFADTVRGIDNVVETRNLRLLLANTDYLAEREEALIRSLLSHQPRGIVVTGG
EECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEECC
HHTPRARTLLEQAGIPVIETWELPEQPIDRVVGFSNRDAAQAMTRYLYQRGYRRIGFIGS
CCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCC
SSLLDLRGIARRNGYLAAVEEAGRHAPRDVVRPMPASDMAHGAAMGHSRAALGQLLAQWP
CCHHHHHHHHHCCCCEEEHHHHCCCCCHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCC
DTDAVMCTSDIHAFGAIMACHRLGLTVPGDLAVAGFGDFEVARHCYPSITTVSVDAYGIG
CCCEEEECHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCCC
HAAGRSLLAAIDGSERPSASRREIASQRAQRQQHDAPPLIRIPYAVVARESA
HHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]