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The map label for this gene is thiM [H]

Identifier: 238027131

GI number: 238027131

Start: 1676136

End: 1676921

Strand: Direct

Name: thiM [H]

Synonym: bglu_1g15110

Alternate gene names: 238027131

Gene position: 1676136-1676921 (Clockwise)

Preceding gene: 238027130

Following gene: 238027133

Centisome position: 42.91

GC content: 70.87

Gene sequence:

>786_bases
ATGACTCGGCAAATTTCATGGGCTGACGCGGCGGTGCGCGCCGAACTGGCGGCACTGCAGCGAGCCCGGCCGTTCGTCTA
TGGCCTGACCAACTACATTGCGGCCAATCTCAGCGCAAACGTGCTGTTGGCCGTGGGCGGCGCGCCGGCCATCGGCGCCG
CGCTCGACTGGCCGACCCGCTTCGCTGCGGCGGCGGCCGGGCTGTGGATCAACGGCGCCGCGCTCGTCAGCAGCGCGCCG
GACACGCTCGAGGCGGCCGCATGCTCGGCGCACGAGGCAGGCACGCCGTGGGTGCTCGATCCGGTGGCGTTCGGGGCCGG
CAGCCCCGAGTACGACGCGGCCCTGCAACGGCTGCTGCGTTACAAGCCAACCGCAATCCGCGGCAATGCAAGCGAGCTGA
TCGCGCTCGCGGGCGGCAATGCCGGTGCCAAGGGCGTGGAGAGCACCGCGCGCTCCGACGAGGCGATCGCGGTGATCAAG
CGCTTCGCGAAAGAGAGCGGTGCGGTGATGGCCGTCAGCGGGGAAGTGGATTACGTGACCGACGGCGACACGCTGCTTGC
CGTCAGCGGCGGCGACCTGCGCCTCACCCGTGTCACCGGCGCCGGCTGCGCGCTTGCCGCTTTGATCGCGGGCTTGCTGG
CGAATGCCCGCTCCCCGCTCGAGGCCACGGCAGCGGCGCACGCGATCTACAAGATAGCGGCGCAACGCGCCGCATCGGCA
CGCGGCACCGGCTCGTTTGCCGTGGCCTTCGTCGACGAACTGTCCTTGCTCGACCCGGCCGCCTGA

Upstream 100 bases:

>100_bases
CTTGCCTGACCGTCCCGGCAAGGCCCGACCCGCCACGGACAGGGAACTTCCGGCAGGCGCGGCCTGAACGCTCATCGCAA
CGCTCTTTCAGGAGATCGAC

Downstream 100 bases:

>100_bases
GGACAGTGCCGCCCGTTCGCCGCCGAGCCGCGCGGCACCCGGCAGCGGGCAGCGGGCAGCGCCGCGCGATCTCCTCGCCG
TGCCGGCTCGAATGCCGCGA

Product: hydroxyethylthiazole kinase family superfamily

Products: NA

Alternate protein names: 4-methyl-5-beta-hydroxyethylthiazole kinase; TH kinase; Thz kinase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTRQISWADAAVRAELAALQRARPFVYGLTNYIAANLSANVLLAVGGAPAIGAALDWPTRFAAAAAGLWINGAALVSSAP
DTLEAAACSAHEAGTPWVLDPVAFGAGSPEYDAALQRLLRYKPTAIRGNASELIALAGGNAGAKGVESTARSDEAIAVIK
RFAKESGAVMAVSGEVDYVTDGDTLLAVSGGDLRLTRVTGAGCALAALIAGLLANARSPLEATAAAHAIYKIAAQRAASA
RGTGSFAVAFVDELSLLDPAA

Sequences:

>Translated_261_residues
MTRQISWADAAVRAELAALQRARPFVYGLTNYIAANLSANVLLAVGGAPAIGAALDWPTRFAAAAAGLWINGAALVSSAP
DTLEAAACSAHEAGTPWVLDPVAFGAGSPEYDAALQRLLRYKPTAIRGNASELIALAGGNAGAKGVESTARSDEAIAVIK
RFAKESGAVMAVSGEVDYVTDGDTLLAVSGGDLRLTRVTGAGCALAALIAGLLANARSPLEATAAAHAIYKIAAQRAASA
RGTGSFAVAFVDELSLLDPAA
>Mature_260_residues
TRQISWADAAVRAELAALQRARPFVYGLTNYIAANLSANVLLAVGGAPAIGAALDWPTRFAAAAAGLWINGAALVSSAPD
TLEAAACSAHEAGTPWVLDPVAFGAGSPEYDAALQRLLRYKPTAIRGNASELIALAGGNAGAKGVESTARSDEAIAVIKR
FAKESGAVMAVSGEVDYVTDGDTLLAVSGGDLRLTRVTGAGCALAALIAGLLANARSPLEATAAAHAIYKIAAQRAASAR
GTGSFAVAFVDELSLLDPAA

Specific function: Thiamine biosynthesis. [C]

COG id: COG2145

COG function: function code H; Hydroxyethylthiazole kinase, sugar kinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Thz kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788421, Length=241, Percent_Identity=41.0788381742739, Blast_Score=164, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6325042, Length=285, Percent_Identity=27.719298245614, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000417 [H]

Pfam domain/function: PF02110 HK [H]

EC number: =2.7.1.50 [H]

Molecular weight: Translated: 26302; Mature: 26171

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRQISWADAAVRAELAALQRARPFVYGLTNYIAANLSANVLLAVGGAPAIGAALDWPTR
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHH
FAAAAAGLWINGAALVSSAPDTLEAAACSAHEAGTPWVLDPVAFGAGSPEYDAALQRLLR
HHHHHHCCEECCHHHCCCCCCHHHHHHHCCCCCCCCEEECCHHCCCCCCHHHHHHHHHHH
YKPTAIRGNASELIALAGGNAGAKGVESTARSDEAIAVIKRFAKESGAVMAVSGEVDYVT
CCCCEECCCHHHEEEEECCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCEEEEECCEEEEE
DGDTLLAVSGGDLRLTRVTGAGCALAALIAGLLANARSPLEATAAAHAIYKIAAQRAASA
CCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
RGTGSFAVAFVDELSLLDPAA
CCCCCEEEEEEHHHHHCCCCC
>Mature Secondary Structure 
TRQISWADAAVRAELAALQRARPFVYGLTNYIAANLSANVLLAVGGAPAIGAALDWPTR
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHH
FAAAAAGLWINGAALVSSAPDTLEAAACSAHEAGTPWVLDPVAFGAGSPEYDAALQRLLR
HHHHHHCCEECCHHHCCCCCCHHHHHHHCCCCCCCCEEECCHHCCCCCCHHHHHHHHHHH
YKPTAIRGNASELIALAGGNAGAKGVESTARSDEAIAVIKRFAKESGAVMAVSGEVDYVT
CCCCEECCCHHHEEEEECCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCEEEEECCEEEEE
DGDTLLAVSGGDLRLTRVTGAGCALAALIAGLLANARSPLEATAAAHAIYKIAAQRAASA
CCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
RGTGSFAVAFVDELSLLDPAA
CCCCCEEEEEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA