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The map label for this gene is dxs [H]

Identifier: 238026700

GI number: 238026700

Start: 1154998

End: 1156944

Strand: Reverse

Name: dxs [H]

Synonym: bglu_1g10570

Alternate gene names: 238026700

Gene position: 1156944-1154998 (Counterclockwise)

Preceding gene: 238026701

Following gene: 238026699

Centisome position: 29.62

GC content: 70.16

Gene sequence:

>1947_bases
ATGTACGACTTGCTGAACACCATCGACGATCCCGCGGACCTGCGCCGCCTCGATCGCCGCCAGTTGCGTCCGCTTGCCGA
CGAGCTGCGCGCCTTCGTGCTCGACAGCGTCTCGAAGACGGGTGGCCACCTCTCGCCGAACCTCGGCACCGTCGAGCTGA
CGATCGCGCTGCACTACGTATTCGACACGCCGCGCGACCGCATCGTCTGGGACGTCGGCCACCAGACCTACCCGCACAAG
ATCCTGACCGGGCGCCGCGAGCAGATGCCCACGCTGCGCCAGATCGGCGGCATCTCGGGCTTCCCGGTGCGCACCGAGTC
GGTGTACGACACGTTCGGCACCGCGCACTCGAGCACCTCGATCTCGGCCGCGTTCGGCATGGCGGTCGCCGCGAAGCTGC
AGGACAGCGAGCGCCGCGCGATCGCCGTGATCGGCGACGGCGCGATGACGGCCGGCATGGCCTTCGAGGCGATGAACAAC
GCCGGGGTGGCCGACGACGTGCCGCTGATCGTGATCCTGAACGACAACGACATGTCGATCTCGCCGCCCGTGGGCGCGCT
CAACCGCCATCTCGCGCGCCTAATGTCGGGCCGCTTCTACGCGGCCGCGCGCGCCGGGGTGGAGCGCGTGCTGAGCGTCG
CGCCGCCGATGCTCGGCCTGGCCCGCAAGCTCGAGGAGCACGCCAAGGGCATGATCATGCCGGCCACCATGTTCGAGGAG
TTCGGCTTCAACTACATCGGCCCGATCGACGGCCACGATCTCGACGCGCTGATCCCCACGCTGCGCAACATCAAGGGCCT
GCGCGGCCCGCAGTTCCTGCACGTGGTGACGAAGAAGGGCCTCGGCTACAAGCTCGCCGAGGCCGATCCGGTGCTCTACC
ACGGCCCCGGCAAGTTCAATCCGGCCGAGGGCATCCGGCCGCCGGCCACGCCGCCGCGCAAGACCTACGCGCAGGTGTTC
GGCGAATGGCTCTGCGACGCCGCCGAACTGGACGCGCGGGTGGTCGGCATCACGCCGGCGATGCGCGAGGGCTCGGGCAT
GGTCGAGTTCGAGAAACGCTTCCCCGCGCGCTACTACGACGTCGGCATCGCCGAGCAGCATGCCGTGACGTTCGCGGCCG
GGCTCGCCACCGAGGGGCTCAAGCCGGTGGTGGCGATCTATTCGACGTTCCTGCAGCGCGCCTATGACCAGTTGATCCAC
GACGTCGCGCTGCAGAACCTGCCGGTGGTGTTCGCGATCGACCGGGCCGGCATCGTCGGCGCCGACGGCGCGACGCACGC
GGGCGCCTATGATTTCGCGTTCCTGCGCTGCATCCCGAACATGACGGTGATGGCCGCCTCGGACGAGAACGAATGCCGTC
AGATGCTCTACACGGCGCTGCAGCAGCCGAATCCGACGGCGGTACGCTATCCGCGCGGCGCCGGCCCCGGCGTCGCCACC
GCCAGGCAGATGGAAGCGCTGCCGATCGGCCGCGGCGAGATACGGCGCCGCTCCACGCAGCAGGAAGGCCAGCGCATCGC
GATCCTCGCGTTCGGCACGATGGTCACGCCCGCGCTGGCCGCCGCCGAGGAGATCGACGCGACCGTGGCCAACATGCGCT
TCGTGAAGCCGCTCGACGTGGAACTGGTGCGTCAGCTCGCCGAAACCCACGACGCGATCGTCACGGTGGAGGAAGCGGCC
GTGATGGGCGGGGCCGGCTCGGCCTGCGTGGAAGCGCTGATGGCGGACGGGCCGCTGCGGCCCGTGCTGCAGCTCGGCCT
GCCCGACCGCTTCATCGATCACGGCGATCCGGCCAAGCTGCTGGCCGGCTGCGGCCTCGACGGCGCCGGCATCGCGCAGT
CGATTCGCGCACGCTTCATCGAGCCGCCCGCCGCGGCCGCGGCCGGCCCGTCGAGGAAGCGCGGCGACACGCTCGCATTC
GCGACGAAAGCGGCGCGCTCGGCATGA

Upstream 100 bases:

>100_bases
GTTACCGCTCCTCGGCGCCACGGCCGGATCACGCCGCACACGCGACGCCTGCCGCGCCAGCGACGTACCGTGCCGCCGGT
TCCCCCACCATGGAACGACC

Downstream 100 bases:

>100_bases
CGAGGCCGGCAGCGTGCCGCGTGCCGGCCGCCCGCCGCTGCGTCTGCCCGGGTGCGCCGGCCTCGCGCGGCGACGACGGA
TGAGGCGCAAGCCCCCGCCG

Product: 1-deoxy-D-xylulose-5-phosphate synthase

Products: NA

Alternate protein names: 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS [H]

Number of amino acids: Translated: 648; Mature: 648

Protein sequence:

>648_residues
MYDLLNTIDDPADLRRLDRRQLRPLADELRAFVLDSVSKTGGHLSPNLGTVELTIALHYVFDTPRDRIVWDVGHQTYPHK
ILTGRREQMPTLRQIGGISGFPVRTESVYDTFGTAHSSTSISAAFGMAVAAKLQDSERRAIAVIGDGAMTAGMAFEAMNN
AGVADDVPLIVILNDNDMSISPPVGALNRHLARLMSGRFYAAARAGVERVLSVAPPMLGLARKLEEHAKGMIMPATMFEE
FGFNYIGPIDGHDLDALIPTLRNIKGLRGPQFLHVVTKKGLGYKLAEADPVLYHGPGKFNPAEGIRPPATPPRKTYAQVF
GEWLCDAAELDARVVGITPAMREGSGMVEFEKRFPARYYDVGIAEQHAVTFAAGLATEGLKPVVAIYSTFLQRAYDQLIH
DVALQNLPVVFAIDRAGIVGADGATHAGAYDFAFLRCIPNMTVMAASDENECRQMLYTALQQPNPTAVRYPRGAGPGVAT
ARQMEALPIGRGEIRRRSTQQEGQRIAILAFGTMVTPALAAAEEIDATVANMRFVKPLDVELVRQLAETHDAIVTVEEAA
VMGGAGSACVEALMADGPLRPVLQLGLPDRFIDHGDPAKLLAGCGLDGAGIAQSIRARFIEPPAAAAAGPSRKRGDTLAF
ATKAARSA

Sequences:

>Translated_648_residues
MYDLLNTIDDPADLRRLDRRQLRPLADELRAFVLDSVSKTGGHLSPNLGTVELTIALHYVFDTPRDRIVWDVGHQTYPHK
ILTGRREQMPTLRQIGGISGFPVRTESVYDTFGTAHSSTSISAAFGMAVAAKLQDSERRAIAVIGDGAMTAGMAFEAMNN
AGVADDVPLIVILNDNDMSISPPVGALNRHLARLMSGRFYAAARAGVERVLSVAPPMLGLARKLEEHAKGMIMPATMFEE
FGFNYIGPIDGHDLDALIPTLRNIKGLRGPQFLHVVTKKGLGYKLAEADPVLYHGPGKFNPAEGIRPPATPPRKTYAQVF
GEWLCDAAELDARVVGITPAMREGSGMVEFEKRFPARYYDVGIAEQHAVTFAAGLATEGLKPVVAIYSTFLQRAYDQLIH
DVALQNLPVVFAIDRAGIVGADGATHAGAYDFAFLRCIPNMTVMAASDENECRQMLYTALQQPNPTAVRYPRGAGPGVAT
ARQMEALPIGRGEIRRRSTQQEGQRIAILAFGTMVTPALAAAEEIDATVANMRFVKPLDVELVRQLAETHDAIVTVEEAA
VMGGAGSACVEALMADGPLRPVLQLGLPDRFIDHGDPAKLLAGCGLDGAGIAQSIRARFIEPPAAAAAGPSRKRGDTLAF
ATKAARSA
>Mature_648_residues
MYDLLNTIDDPADLRRLDRRQLRPLADELRAFVLDSVSKTGGHLSPNLGTVELTIALHYVFDTPRDRIVWDVGHQTYPHK
ILTGRREQMPTLRQIGGISGFPVRTESVYDTFGTAHSSTSISAAFGMAVAAKLQDSERRAIAVIGDGAMTAGMAFEAMNN
AGVADDVPLIVILNDNDMSISPPVGALNRHLARLMSGRFYAAARAGVERVLSVAPPMLGLARKLEEHAKGMIMPATMFEE
FGFNYIGPIDGHDLDALIPTLRNIKGLRGPQFLHVVTKKGLGYKLAEADPVLYHGPGKFNPAEGIRPPATPPRKTYAQVF
GEWLCDAAELDARVVGITPAMREGSGMVEFEKRFPARYYDVGIAEQHAVTFAAGLATEGLKPVVAIYSTFLQRAYDQLIH
DVALQNLPVVFAIDRAGIVGADGATHAGAYDFAFLRCIPNMTVMAASDENECRQMLYTALQQPNPTAVRYPRGAGPGVAT
ARQMEALPIGRGEIRRRSTQQEGQRIAILAFGTMVTPALAAAEEIDATVANMRFVKPLDVELVRQLAETHDAIVTVEEAA
VMGGAGSACVEALMADGPLRPVLQLGLPDRFIDHGDPAKLLAGCGLDGAGIAQSIRARFIEPPAAAAAGPSRKRGDTLAF
ATKAARSA

Specific function: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) [H]

COG id: COG1154

COG function: function code HI; Deoxyxylulose-5-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family. DXPS subfamily [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=665, Percent_Identity=24.812030075188, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI4507521, Length=665, Percent_Identity=24.812030075188, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI225637463, Length=255, Percent_Identity=28.2352941176471, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI225637459, Length=255, Percent_Identity=28.2352941176471, Blast_Score=81, Evalue=4e-15,
Organism=Homo sapiens, GI225637461, Length=255, Percent_Identity=28.2352941176471, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI133778974, Length=532, Percent_Identity=22.7443609022556, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1786622, Length=618, Percent_Identity=57.6051779935275, Blast_Score=734, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=645, Percent_Identity=24.3410852713178, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24666278, Length=627, Percent_Identity=24.7208931419458, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI45551847, Length=625, Percent_Identity=24.8, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45550715, Length=625, Percent_Identity=24.8, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24645119, Length=538, Percent_Identity=25.4646840148699, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001017
- InterPro:   IPR005477
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00676 E1_dh; PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.7 [H]

Molecular weight: Translated: 69619; Mature: 69619

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDLLNTIDDPADLRRLDRRQLRPLADELRAFVLDSVSKTGGHLSPNLGTVELTIALHYV
CCCHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEE
FDTPRDRIVWDVGHQTYPHKILTGRREQMPTLRQIGGISGFPVRTESVYDTFGTAHSSTS
ECCCCCCEEEECCCCCCCHHHHCCCHHCCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCC
ISAAFGMAVAAKLQDSERRAIAVIGDGAMTAGMAFEAMNNAGVADDVPLIVILNDNDMSI
HHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC
SPPVGALNRHLARLMSGRFYAAARAGVERVLSVAPPMLGLARKLEEHAKGMIMPATMFEE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEHHHHHHH
FGFNYIGPIDGHDLDALIPTLRNIKGLRGPQFLHVVTKKGLGYKLAEADPVLYHGPGKFN
CCCCEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHCCCCEEECCCCCEEEECCCCCC
PAEGIRPPATPPRKTYAQVFGEWLCDAAELDARVVGITPAMREGSGMVEFEKRFPARYYD
CCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCEEEECCCCHHCCCCCCHHHHHCCCCEEE
VGIAEQHAVTFAAGLATEGLKPVVAIYSTFLQRAYDQLIHDVALQNLPVVFAIDRAGIVG
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEE
ADGATHAGAYDFAFLRCIPNMTVMAASDENECRQMLYTALQQPNPTAVRYPRGAGPGVAT
CCCCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHH
ARQMEALPIGRGEIRRRSTQQEGQRIAILAFGTMVTPALAAAEEIDATVANMRFVKPLDV
HHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCEECCCCCH
ELVRQLAETHDAIVTVEEAAVMGGAGSACVEALMADGPLRPVLQLGLPDRFIDHGDPAKL
HHHHHHHHHHHHEEEEHHHHHCCCCCHHHHHHHHCCCCCCHHHHCCCCHHHHCCCCHHHH
LAGCGLDGAGIAQSIRARFIEPPAAAAAGPSRKRGDTLAFATKAARSA
HHHCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MYDLLNTIDDPADLRRLDRRQLRPLADELRAFVLDSVSKTGGHLSPNLGTVELTIALHYV
CCCHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEE
FDTPRDRIVWDVGHQTYPHKILTGRREQMPTLRQIGGISGFPVRTESVYDTFGTAHSSTS
ECCCCCCEEEECCCCCCCHHHHCCCHHCCCHHHHHCCCCCCCCCCHHHHHHHCCCCCCCC
ISAAFGMAVAAKLQDSERRAIAVIGDGAMTAGMAFEAMNNAGVADDVPLIVILNDNDMSI
HHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCC
SPPVGALNRHLARLMSGRFYAAARAGVERVLSVAPPMLGLARKLEEHAKGMIMPATMFEE
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEHHHHHHH
FGFNYIGPIDGHDLDALIPTLRNIKGLRGPQFLHVVTKKGLGYKLAEADPVLYHGPGKFN
CCCCEECCCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHCCCCEEECCCCCEEEECCCCCC
PAEGIRPPATPPRKTYAQVFGEWLCDAAELDARVVGITPAMREGSGMVEFEKRFPARYYD
CCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCEEEECCCCHHCCCCCCHHHHHCCCCEEE
VGIAEQHAVTFAAGLATEGLKPVVAIYSTFLQRAYDQLIHDVALQNLPVVFAIDRAGIVG
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEE
ADGATHAGAYDFAFLRCIPNMTVMAASDENECRQMLYTALQQPNPTAVRYPRGAGPGVAT
CCCCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHH
ARQMEALPIGRGEIRRRSTQQEGQRIAILAFGTMVTPALAAAEEIDATVANMRFVKPLDV
HHHHHCCCCCCHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCEECCCCCH
ELVRQLAETHDAIVTVEEAAVMGGAGSACVEALMADGPLRPVLQLGLPDRFIDHGDPAKL
HHHHHHHHHHHHEEEEHHHHHCCCCCHHHHHHHHCCCCCCHHHHCCCCHHHHCCCCHHHH
LAGCGLDGAGIAQSIRARFIEPPAAAAAGPSRKRGDTLAFATKAARSA
HHHCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA