Click here to switch to the map view.

The map label for this gene is adiA [H]

Identifier: 238026521

GI number: 238026521

Start: 939206

End: 941503

Strand: Reverse

Name: adiA [H]

Synonym: bglu_1g08650

Alternate gene names: 238026521

Gene position: 941503-939206 (Counterclockwise)

Preceding gene: 238026522

Following gene: 238026519

Centisome position: 24.1

GC content: 65.32

Gene sequence:

>2298_bases
ATGAACCATCGCGACAACAAGCATTTCCCGATCCTCGTCATCGGTTTCGACAAGGAATCGATGAGCAAGCCCGGCGCCGA
GGAGGTCCAAAAGATCGGCCGGTTGCTGAAAGACGGCTATGGCTACTCGATCCTCCACGAAACGACGCTGAAACCGGGCC
TGCTGACGAAGGAGGCGGAAAGCACGCTCGGCTGCATCGTGATCGACGCCGATCTCTGCGGCGGCGAGCAGGACGGCCTG
CACTACATCTCGCTGATCGAGGAAATCCGGCGCCACAACACCGGCGTGCCGATCATCCTCGCGGCCGAACGCGCCGTGAT
GACCGACCTGCCGATCGGCATCCTCGGCGAGGTGCGCGAATACGTCCATCTGGGCCAGGACACCTCGACCTTCATCGCCG
GACGCATCGATTTCGCCGTGAAGCAGTACATGGATTCGCTGCTGCCGCCGTACTTCAAGGCGCTCAAGTCGTATGCCGAG
GACCGCCCCTACTACTGGGACTGCCCCGGCCATCAGGGCGGGGTGGCCTACCTCAAGCATCCGGTCGGCCGCGAGTTCCT
GCGCTTCTTCGGCGAAAACATCATGCGCGCCGATATCGGCATCGCGACGCCCGATCTCGGCAACTGGCTCGAACATCGCG
GCGTGCCCGGCGAATCGGAACGCGAGGCGGCCCGCACCTTCGGTGCCGATGCCACCTATTACGTGGTCGGCGGCTCCTCG
CAGTCGAATCAGATCGTCGGCCATGCGTTGCTGCGGCCCGACGAGATGGTGCTGGTCGACCGCAACTGCCACAAGTCGGT
GAACCACGAGCTCACCATCACGGGCGCGCGGCCGATCTACTTCAAGCCGGCCCGCAACGGCTACGGGCTGATCGGGCTGA
TCCCGCCCGAGCAGTTCGAGGCGGCGGCGATTCGCGACGAGATCGCGACGAGCCCGATGCATCGAGAGGCGCGCGGCAAG
GCGCCGGTCTACGCGGTGGTGACCAACTCCACCTACGACGGCCTGATCTACGACGTCGACCGCATCACGCGCCAACTGGC
GGGATCGGTGCCACGCATCAAGTTCGACGAGGCCTGGTATGCCTACGCGAAATTCCATCCGCTCTACGCGGGCCGCTACG
CAATGGGCGTGCCGGAAGACCTGCCCGAGCGGCCGACGCTGATCGCGGTGCAGTCCACGCACAAGATGCTCGCGGCGTTC
TCGTCGGCCTCGATGATCCACATTCGCAACAGCGAACGCGCGCCGATCGATCACGACGTGTTCAACCAGTCGTTCATGAT
GCATGGCACGACCTCGCCGTTCTACCCGATCATCGCGTCGATCGACGTCGCCACCTCGATGATGAAGGGCGAATCGGGCA
AGGCGCTGCTGCGCGACGCGATCAACGATGCCGTCGACTTCCGCAAGACGATGCTGACGATGGCCGCCAAGCTCGCGCAA
TCGGGCGACGACGGCTGGTGGTTCGGCGTCTGGCAGCCCACCGAGGTCCAGGTGGACGGCAAGCGCGTGCCGTTCCTCGA
CGTGCCCAACGCCACGCTCGAGCGCGATCCGACCTGCTGGTGGCTGCGTGCCAACGAGGCATGGCACGGCTTCGGCGAGA
TCGAGGACGGCTACGCGATGCTCGATCCGATCAAGGTGACGATCACCTGCCCCGGCATCGACGCGCTCGGCCGCGAGACG
GATTTCGGCATTCCCGCGCCGATCGTCTCGCGCTTTCTCGGCACGCGCCGTACGATCCCGGCCCGCAACGGCGACTACAA
CCTCCTGATCCTCTATGCGCTCGGCTCGACGCAAGGCAAGTGGGGGACGCTGATCGAATCGCTGCTCGAATTCAAGCGCC
TGCACGACACCGACGCGAGCCTCGCCACGGCGCTGCCCGAACTCGTCGCGCTGTCGCCGCGCTACCGCGACATGACGCTG
CGCGAACTCTGCGCAGCGATCCACCAGAGCAAGCGCGAGCTGAAGATGACGCAGTTGTCCGACGCGGCCTGCACCGCCAA
GGCCTCGCCCGTGATGTCGCCGGGCGAGGCGTATCAACGGCTCATCAGCGACGGTACCGAGAAGGTACGCGTGCGCGACA
TGGTGGGGCGGACCGTCGGCGTGATGGTCACGCCCTACCCTCCAGGCATCCCGGTCATCATGCCCGGCGAACGCGTCGCG
CCCGACGCGCACGCCATCGTCGACTACCTGCTCGCCATGGAGCGGTTCAGCCGGCTGTTCCCTGGGTTCGAATCGGAACT
GCAAGGCGTCGATGTCGACGACGAAGGCAACTACTGGGTGCGCTGCCTGAAGCCATGA

Upstream 100 bases:

>100_bases
AGGCATCACATGCAGGCATGCATGCCCGCATCCGGATTCATTTTATAAGGAATACGAACCAGCCCGGCGAGGCCGCGGCA
GGTTACTTCGGAGCAATTTC

Downstream 100 bases:

>100_bases
GGCCGTGAAGCCATGAGGCCGTGACGGACGAGGCACGCGGGCCGCGGCGGCCGCATGCGCCGCGGCGCTGCCGTCGTCCT
TCACGCGCGTCACCATTCGA

Product: Lysine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 765; Mature: 765

Protein sequence:

>765_residues
MNHRDNKHFPILVIGFDKESMSKPGAEEVQKIGRLLKDGYGYSILHETTLKPGLLTKEAESTLGCIVIDADLCGGEQDGL
HYISLIEEIRRHNTGVPIILAAERAVMTDLPIGILGEVREYVHLGQDTSTFIAGRIDFAVKQYMDSLLPPYFKALKSYAE
DRPYYWDCPGHQGGVAYLKHPVGREFLRFFGENIMRADIGIATPDLGNWLEHRGVPGESEREAARTFGADATYYVVGGSS
QSNQIVGHALLRPDEMVLVDRNCHKSVNHELTITGARPIYFKPARNGYGLIGLIPPEQFEAAAIRDEIATSPMHREARGK
APVYAVVTNSTYDGLIYDVDRITRQLAGSVPRIKFDEAWYAYAKFHPLYAGRYAMGVPEDLPERPTLIAVQSTHKMLAAF
SSASMIHIRNSERAPIDHDVFNQSFMMHGTTSPFYPIIASIDVATSMMKGESGKALLRDAINDAVDFRKTMLTMAAKLAQ
SGDDGWWFGVWQPTEVQVDGKRVPFLDVPNATLERDPTCWWLRANEAWHGFGEIEDGYAMLDPIKVTITCPGIDALGRET
DFGIPAPIVSRFLGTRRTIPARNGDYNLLILYALGSTQGKWGTLIESLLEFKRLHDTDASLATALPELVALSPRYRDMTL
RELCAAIHQSKRELKMTQLSDAACTAKASPVMSPGEAYQRLISDGTEKVRVRDMVGRTVGVMVTPYPPGIPVIMPGERVA
PDAHAIVDYLLAMERFSRLFPGFESELQGVDVDDEGNYWVRCLKP

Sequences:

>Translated_765_residues
MNHRDNKHFPILVIGFDKESMSKPGAEEVQKIGRLLKDGYGYSILHETTLKPGLLTKEAESTLGCIVIDADLCGGEQDGL
HYISLIEEIRRHNTGVPIILAAERAVMTDLPIGILGEVREYVHLGQDTSTFIAGRIDFAVKQYMDSLLPPYFKALKSYAE
DRPYYWDCPGHQGGVAYLKHPVGREFLRFFGENIMRADIGIATPDLGNWLEHRGVPGESEREAARTFGADATYYVVGGSS
QSNQIVGHALLRPDEMVLVDRNCHKSVNHELTITGARPIYFKPARNGYGLIGLIPPEQFEAAAIRDEIATSPMHREARGK
APVYAVVTNSTYDGLIYDVDRITRQLAGSVPRIKFDEAWYAYAKFHPLYAGRYAMGVPEDLPERPTLIAVQSTHKMLAAF
SSASMIHIRNSERAPIDHDVFNQSFMMHGTTSPFYPIIASIDVATSMMKGESGKALLRDAINDAVDFRKTMLTMAAKLAQ
SGDDGWWFGVWQPTEVQVDGKRVPFLDVPNATLERDPTCWWLRANEAWHGFGEIEDGYAMLDPIKVTITCPGIDALGRET
DFGIPAPIVSRFLGTRRTIPARNGDYNLLILYALGSTQGKWGTLIESLLEFKRLHDTDASLATALPELVALSPRYRDMTL
RELCAAIHQSKRELKMTQLSDAACTAKASPVMSPGEAYQRLISDGTEKVRVRDMVGRTVGVMVTPYPPGIPVIMPGERVA
PDAHAIVDYLLAMERFSRLFPGFESELQGVDVDDEGNYWVRCLKP
>Mature_765_residues
MNHRDNKHFPILVIGFDKESMSKPGAEEVQKIGRLLKDGYGYSILHETTLKPGLLTKEAESTLGCIVIDADLCGGEQDGL
HYISLIEEIRRHNTGVPIILAAERAVMTDLPIGILGEVREYVHLGQDTSTFIAGRIDFAVKQYMDSLLPPYFKALKSYAE
DRPYYWDCPGHQGGVAYLKHPVGREFLRFFGENIMRADIGIATPDLGNWLEHRGVPGESEREAARTFGADATYYVVGGSS
QSNQIVGHALLRPDEMVLVDRNCHKSVNHELTITGARPIYFKPARNGYGLIGLIPPEQFEAAAIRDEIATSPMHREARGK
APVYAVVTNSTYDGLIYDVDRITRQLAGSVPRIKFDEAWYAYAKFHPLYAGRYAMGVPEDLPERPTLIAVQSTHKMLAAF
SSASMIHIRNSERAPIDHDVFNQSFMMHGTTSPFYPIIASIDVATSMMKGESGKALLRDAINDAVDFRKTMLTMAAKLAQ
SGDDGWWFGVWQPTEVQVDGKRVPFLDVPNATLERDPTCWWLRANEAWHGFGEIEDGYAMLDPIKVTITCPGIDALGRET
DFGIPAPIVSRFLGTRRTIPARNGDYNLLILYALGSTQGKWGTLIESLLEFKRLHDTDASLATALPELVALSPRYRDMTL
RELCAAIHQSKRELKMTQLSDAACTAKASPVMSPGEAYQRLISDGTEKVRVRDMVGRTVGVMVTPYPPGIPVIMPGERVA
PDAHAIVDYLLAMERFSRLFPGFESELQGVDVDDEGNYWVRCLKP

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=728, Percent_Identity=38.5989010989011, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI1790573, Length=704, Percent_Identity=36.9318181818182, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI1786384, Length=698, Percent_Identity=36.8194842406877, Blast_Score=478, Evalue=1e-136,
Organism=Escherichia coli, GI1786909, Length=693, Percent_Identity=33.1890331890332, Blast_Score=367, Evalue=1e-102,
Organism=Escherichia coli, GI87082193, Length=674, Percent_Identity=34.1246290801187, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 85026; Mature: 85026

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHRDNKHFPILVIGFDKESMSKPGAEEVQKIGRLLKDGYGYSILHETTLKPGLLTKEAE
CCCCCCCCCCEEEEECCHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
STLGCIVIDADLCGGEQDGLHYISLIEEIRRHNTGVPIILAAERAVMTDLPIGILGEVRE
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHCCCHHHHHHHHH
YVHLGQDTSTFIAGRIDFAVKQYMDSLLPPYFKALKSYAEDRPYYWDCPGHQGGVAYLKH
HHHCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHC
PVGREFLRFFGENIMRADIGIATPDLGNWLEHRGVPGESEREAARTFGADATYYVVGGSS
CCHHHHHHHHCCHHEECCCCCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEECCC
QSNQIVGHALLRPDEMVLVDRNCHKSVNHELTITGARPIYFKPARNGYGLIGLIPPEQFE
CCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCEEEEECCCHHHH
AAAIRDEIATSPMHREARGKAPVYAVVTNSTYDGLIYDVDRITRQLAGSVPRIKFDEAWY
HHHHHHHHHCCCCCHHHCCCCCEEEEEECCCCCCCEEEHHHHHHHHHCCCCCEEECCCEE
AYAKFHPLYAGRYAMGVPEDLPERPTLIAVQSTHKMLAAFSSASMIHIRNSERAPIDHDV
EHHEECCCCCCCEECCCCCCCCCCCEEEEEEHHHHHHHHHCCCCEEEEECCCCCCCCHHH
FNQSFMMHGTTSPFYPIIASIDVATSMMKGESGKALLRDAINDAVDFRKTMLTMAAKLAQ
HCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGDDGWWFGVWQPTEVQVDGKRVPFLDVPNATLERDPTCWWLRANEAWHGFGEIEDGYAM
CCCCCEEEEECCCCEEEECCCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEE
LDPIKVTITCPGIDALGRETDFGIPAPIVSRFLGTRRTIPARNGDYNLLILYALGSTQGK
ECCEEEEEECCCCHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCH
WGTLIESLLEFKRLHDTDASLATALPELVALSPRYRDMTLRELCAAIHQSKRELKMTQLS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DAACTAKASPVMSPGEAYQRLISDGTEKVRVRDMVGRTVGVMVTPYPPGIPVIMPGERVA
CHHHCCCCCCCCCHHHHHHHHHHCCHHHEEHHHHHCCEEEEEEECCCCCCCEECCCCCCC
PDAHAIVDYLLAMERFSRLFPGFESELQGVDVDDEGNYWVRCLKP
CHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MNHRDNKHFPILVIGFDKESMSKPGAEEVQKIGRLLKDGYGYSILHETTLKPGLLTKEAE
CCCCCCCCCCEEEEECCHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
STLGCIVIDADLCGGEQDGLHYISLIEEIRRHNTGVPIILAAERAVMTDLPIGILGEVRE
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCHHHHCCCHHHHHHHHH
YVHLGQDTSTFIAGRIDFAVKQYMDSLLPPYFKALKSYAEDRPYYWDCPGHQGGVAYLKH
HHHCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCCHHHHHC
PVGREFLRFFGENIMRADIGIATPDLGNWLEHRGVPGESEREAARTFGADATYYVVGGSS
CCHHHHHHHHCCHHEECCCCCCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEECCC
QSNQIVGHALLRPDEMVLVDRNCHKSVNHELTITGARPIYFKPARNGYGLIGLIPPEQFE
CCCCCHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCEEEEECCCCCEEEEECCCHHHH
AAAIRDEIATSPMHREARGKAPVYAVVTNSTYDGLIYDVDRITRQLAGSVPRIKFDEAWY
HHHHHHHHHCCCCCHHHCCCCCEEEEEECCCCCCCEEEHHHHHHHHHCCCCCEEECCCEE
AYAKFHPLYAGRYAMGVPEDLPERPTLIAVQSTHKMLAAFSSASMIHIRNSERAPIDHDV
EHHEECCCCCCCEECCCCCCCCCCCEEEEEEHHHHHHHHHCCCCEEEEECCCCCCCCHHH
FNQSFMMHGTTSPFYPIIASIDVATSMMKGESGKALLRDAINDAVDFRKTMLTMAAKLAQ
HCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SGDDGWWFGVWQPTEVQVDGKRVPFLDVPNATLERDPTCWWLRANEAWHGFGEIEDGYAM
CCCCCEEEEECCCCEEEECCCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEE
LDPIKVTITCPGIDALGRETDFGIPAPIVSRFLGTRRTIPARNGDYNLLILYALGSTQGK
ECCEEEEEECCCCHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCH
WGTLIESLLEFKRLHDTDASLATALPELVALSPRYRDMTLRELCAAIHQSKRELKMTQLS
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
DAACTAKASPVMSPGEAYQRLISDGTEKVRVRDMVGRTVGVMVTPYPPGIPVIMPGERVA
CHHHCCCCCCCCCHHHHHHHHHHCCHHHEEHHHHHCCEEEEEEECCCCCCCEECCCCCCC
PDAHAIVDYLLAMERFSRLFPGFESELQGVDVDDEGNYWVRCLKP
CHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]