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The map label for this gene is mntH [H]

Identifier: 238026455

GI number: 238026455

Start: 856689

End: 857993

Strand: Direct

Name: mntH [H]

Synonym: bglu_1g07970

Alternate gene names: 238026455

Gene position: 856689-857993 (Clockwise)

Preceding gene: 238026454

Following gene: 238026459

Centisome position: 21.93

GC content: 69.43

Gene sequence:

>1305_bases
ATGCTGATGGCAATCAAACGAACCGCCGGCTATGCCCTGTCCGGCACGGCGACCACCGACACCGTGAGCGCGATGCGCGA
GGTGCTCGACCACCGGCGCCGCGGCGCTCGCGCGCTGCTGTCGTTCGCCGGGCCGGCCGTGATCGCCTCGGTCGGCTACA
TGGACCCGGGCAACTTCGCCACCAACATCCAGGCCGGCTCGACCTACGGCTATGAGCTGCTGTGGGTGGTGCTGCTGTCT
TCGCTGGTGGCGATGCTGTTCCAGGCGATGTCGGCCAAGCTCGGCATCGTCACCGGGCGCAGCCTCGCCGAACTCTGCCG
CGAGGCCTTCCCGAAGCCGCTCGTGATCGGCATGTGGGTCGGCTCCGAGATCGCGGCGATGGCCACCGACCTGGCCGAGT
TCATGGGCGCCGCGATGGGCATCGCGCTGCTGTTCCATCTCGCGATCGGCTGGGGGCTCGCGATCACGGGCGTGGTCACG
ATCGGCATCCTGTCGCTCGACGCGCGCGGCTTCCGCCCGCTCGAGATCGTGATCGCGGCGCTGATCACGGTGATCGGCCT
GAGCTACCTGGGCGAACTCGTGATCGCGCCGCCCGACTGGCACGCCGCGATCTTCCACACCCTCGTGCCGCATCTGCACG
GTAGCGAGGCGCTGATGCTGGCCGTGGGCATCGTCGGCGCCACCATCATGCCGCACACCATCTATCTGCACTCGGGCCTC
ACGCAGAACCGCGCGCCGGCCCGCAACGACCAGCAGCGCCGGCGCCTGGTGCGCTTCTCGAACCGCGAGGTGGCGATCGC
GCTCGGCTTCGCCGGCTTCGTGAACCTCGCGATGGTGGCGATGTCGGCCTCGGTGTTTCGCGAGCATGCGCCCGGCATCT
CCGACATCACGGCCGCCTATCACACGCTGACGCCCGTGCTCGGCACCGGCGCGGCCGCGCTGTTCCTGGTCTCGCTGCTG
GCCTCGGGCATTTCCAGCTCGGTGGTGGGAACCCTGGCCGGCCAGTCGATCATGCAGGGCTTCGTCGGCATGCGCATGCC
GGTGATGGCGCGCCGCCTCGTCACGATGGTGCCGGCGGTGGTGGTCTGCCTGACCTGCAATCCGATGCGCGCCATGATCG
ACAGCCAGATCGTGCTGAGCCTGGTCCTGCCGGTGCCGCTCGTCGCGCTGGTGGTGCTGTCGGCGCGCCGCTCAGTGATG
GGTCGATTCGTGGCGGGCCGCGGGTTGCTGGTTGCCGCCGGCCTCGCCACCGGCGTGATCGTGGTCCTGAACGCGATGCT
GATCTGGCAGGCCGTCGTCGCGTAG

Upstream 100 bases:

>100_bases
GCGAACCCGCCGCACGGCGCGCCACCGCATTCGAGGCTGCCGCGCGGCGGATTCGGAATCCCTTGTCGAGACCCGGCCAT
GCCGGGAAGAGGCCCTCATC

Downstream 100 bases:

>100_bases
CAGCGCGCGCGTGCGCAGCGCCACCTCGAGCCCGGCGCTGCCGGCGACCATCGGCCGAGCAGACGGAGCAGCGAGCGGCT
GGCGCTGACGATCCATGCCC

Product: NRAMP family Mn2 and Fe2 transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MLMAIKRTAGYALSGTATTDTVSAMREVLDHRRRGARALLSFAGPAVIASVGYMDPGNFATNIQAGSTYGYELLWVVLLS
SLVAMLFQAMSAKLGIVTGRSLAELCREAFPKPLVIGMWVGSEIAAMATDLAEFMGAAMGIALLFHLAIGWGLAITGVVT
IGILSLDARGFRPLEIVIAALITVIGLSYLGELVIAPPDWHAAIFHTLVPHLHGSEALMLAVGIVGATIMPHTIYLHSGL
TQNRAPARNDQQRRRLVRFSNREVAIALGFAGFVNLAMVAMSASVFREHAPGISDITAAYHTLTPVLGTGAAALFLVSLL
ASGISSSVVGTLAGQSIMQGFVGMRMPVMARRLVTMVPAVVVCLTCNPMRAMIDSQIVLSLVLPVPLVALVVLSARRSVM
GRFVAGRGLLVAAGLATGVIVVLNAMLIWQAVVA

Sequences:

>Translated_434_residues
MLMAIKRTAGYALSGTATTDTVSAMREVLDHRRRGARALLSFAGPAVIASVGYMDPGNFATNIQAGSTYGYELLWVVLLS
SLVAMLFQAMSAKLGIVTGRSLAELCREAFPKPLVIGMWVGSEIAAMATDLAEFMGAAMGIALLFHLAIGWGLAITGVVT
IGILSLDARGFRPLEIVIAALITVIGLSYLGELVIAPPDWHAAIFHTLVPHLHGSEALMLAVGIVGATIMPHTIYLHSGL
TQNRAPARNDQQRRRLVRFSNREVAIALGFAGFVNLAMVAMSASVFREHAPGISDITAAYHTLTPVLGTGAAALFLVSLL
ASGISSSVVGTLAGQSIMQGFVGMRMPVMARRLVTMVPAVVVCLTCNPMRAMIDSQIVLSLVLPVPLVALVVLSARRSVM
GRFVAGRGLLVAAGLATGVIVVLNAMLIWQAVVA
>Mature_434_residues
MLMAIKRTAGYALSGTATTDTVSAMREVLDHRRRGARALLSFAGPAVIASVGYMDPGNFATNIQAGSTYGYELLWVVLLS
SLVAMLFQAMSAKLGIVTGRSLAELCREAFPKPLVIGMWVGSEIAAMATDLAEFMGAAMGIALLFHLAIGWGLAITGVVT
IGILSLDARGFRPLEIVIAALITVIGLSYLGELVIAPPDWHAAIFHTLVPHLHGSEALMLAVGIVGATIMPHTIYLHSGL
TQNRAPARNDQQRRRLVRFSNREVAIALGFAGFVNLAMVAMSASVFREHAPGISDITAAYHTLTPVLGTGAAALFLVSLL
ASGISSSVVGTLAGQSIMQGFVGMRMPVMARRLVTMVPAVVVCLTCNPMRAMIDSQIVLSLVLPVPLVALVVLSARRSVM
GRFVAGRGLLVAAGLATGVIVVLNAMLIWQAVVA

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=363, Percent_Identity=35.2617079889807, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI295293167, Length=432, Percent_Identity=34.4907407407407, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI295293171, Length=432, Percent_Identity=34.4907407407407, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI295293169, Length=432, Percent_Identity=34.4907407407407, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI295293178, Length=432, Percent_Identity=34.4907407407407, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI295293175, Length=432, Percent_Identity=34.4907407407407, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI295293173, Length=432, Percent_Identity=34.4907407407407, Blast_Score=179, Evalue=6e-45,
Organism=Homo sapiens, GI10835169, Length=432, Percent_Identity=34.4907407407407, Blast_Score=179, Evalue=6e-45,
Organism=Escherichia coli, GI1788736, Length=398, Percent_Identity=45.7286432160804, Blast_Score=315, Evalue=3e-87,
Organism=Caenorhabditis elegans, GI17569473, Length=396, Percent_Identity=31.3131313131313, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI193210616, Length=430, Percent_Identity=30.6976744186047, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71999499, Length=441, Percent_Identity=28.1179138321995, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71993856, Length=225, Percent_Identity=35.5555555555556, Blast_Score=138, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6323062, Length=407, Percent_Identity=30.958230958231, Blast_Score=185, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324450, Length=448, Percent_Identity=28.5714285714286, Blast_Score=172, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6321841, Length=409, Percent_Identity=32.0293398533007, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24648607, Length=433, Percent_Identity=31.8706697459584, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI281362176, Length=433, Percent_Identity=31.8706697459584, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24648609, Length=433, Percent_Identity=31.8706697459584, Blast_Score=195, Evalue=5e-50,
Organism=Drosophila melanogaster, GI45553443, Length=411, Percent_Identity=32.360097323601, Blast_Score=191, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 45618; Mature: 45618

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMAIKRTAGYALSGTATTDTVSAMREVLDHRRRGARALLSFAGPAVIASVGYMDPGNFA
CCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
TNIQAGSTYGYELLWVVLLSSLVAMLFQAMSAKLGIVTGRSLAELCREAFPKPLVIGMWV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEECCHHHHHHHHHHCCCCEEEEEEC
GSEIAAMATDLAEFMGAAMGIALLFHLAIGWGLAITGVVTIGILSLDARGFRPLEIVIAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
LITVIGLSYLGELVIAPPDWHAAIFHTLVPHLHGSEALMLAVGIVGATIMPHTIYLHSGL
HHHHHHHHHHCCEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEECCC
TQNRAPARNDQQRRRLVRFSNREVAIALGFAGFVNLAMVAMSASVFREHAPGISDITAAY
CCCCCCCCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HTLTPVLGTGAAALFLVSLLASGISSSVVGTLAGQSIMQGFVGMRMPVMARRLVTMVPAV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VVCLTCNPMRAMIDSQIVLSLVLPVPLVALVVLSARRSVMGRFVAGRGLLVAAGLATGVI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VVLNAMLIWQAVVA
HHHHHHHHHHHHHC
>Mature Secondary Structure
MLMAIKRTAGYALSGTATTDTVSAMREVLDHRRRGARALLSFAGPAVIASVGYMDPGNFA
CCEEEEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
TNIQAGSTYGYELLWVVLLSSLVAMLFQAMSAKLGIVTGRSLAELCREAFPKPLVIGMWV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEECCHHHHHHHHHHCCCCEEEEEEC
GSEIAAMATDLAEFMGAAMGIALLFHLAIGWGLAITGVVTIGILSLDARGFRPLEIVIAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
LITVIGLSYLGELVIAPPDWHAAIFHTLVPHLHGSEALMLAVGIVGATIMPHTIYLHSGL
HHHHHHHHHHCCEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCEEEEECCC
TQNRAPARNDQQRRRLVRFSNREVAIALGFAGFVNLAMVAMSASVFREHAPGISDITAAY
CCCCCCCCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HTLTPVLGTGAAALFLVSLLASGISSSVVGTLAGQSIMQGFVGMRMPVMARRLVTMVPAV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
VVCLTCNPMRAMIDSQIVLSLVLPVPLVALVVLSARRSVMGRFVAGRGLLVAAGLATGVI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VVLNAMLIWQAVVA
HHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA