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The map label for this gene is purM [H]

Identifier: 238026309

GI number: 238026309

Start: 684994

End: 686049

Strand: Direct

Name: purM [H]

Synonym: bglu_1g06430

Alternate gene names: 238026309

Gene position: 684994-686049 (Clockwise)

Preceding gene: 238026302

Following gene: 238026312

Centisome position: 17.53

GC content: 68.66

Gene sequence:

>1056_bases
ATGACTTCTCCGAAATCCGCTCCCGACGCCCAAGGTCTTTCCTACCGTGACGCGGGCGTCGACATCGACGCGGGCGACGC
GCTCGTCGACAAGATCAAGCCATTTGCCAAGAAAACGCTGCGCGACGGCGTGCTGGGCGGGATCGGCGGATTCGGCGCAC
TGTTCGAAGTGCCGAAGAAGTATCGGGAGCCGGTGCTGGTGTCGGGCACCGACGGCGTGGGCACCAAGCTCAAGCTCGCG
TTCCACCTGAACCGCCACGACACGGTCGGCCAGGATCTGGTGGCGATGAGCGTGAACGACATCCTCGTGCAGGGCGCCGA
GCCGCTGTTCTTCCTCGACTACTTCGCCTGCGGCAAGCTCGACGTCGAGACGGCGGCGACGGTGGTGAAGGGCATCGCGA
CCGGCTGCGAGCTGGCCGGCTGCGCGCTGATCGGCGGCGAGACGGCGGAAATGCCCGGCATGTATCCGGACGGCGAGTAC
GATCTGGCCGGCTTCGCGGTGGGTGCGGTCGAGAAGAGCCGGATCATCGACGGCAGCACCATCGCCGCGGGCGACGTGGT
GCTGGGCCTCGCGTCGAGCGGCATCCACTCGAACGGCTTTTCGCTGGTGCGCAAGATCATCGAGCGCGCCAATCCCGATC
TCGACGCCGCCTTCGACGGCCGCACGCTGGCCGACGCGCTGATCGCGCCGACCCGCATCTACGTGAAGCCGCTGCTCGCG
CTGATGGCCAAGCTGCCCGTCAAGGGCATGGCGCACATCACGGGCGGCGGCCTCGTCGAGAACATCCCGCGCGTGCTGCG
CGAGGGCCTGACGGCCGAACTGGACCAGACCGCCTGGACGCTGCCGCCGCTGTTCCAGTGGCTGCAGCAGCACGGCGGCG
TGGCCGATGCGGAGATGCACCGCGTGTTCAATTGCGGGATCGGGATGGCCGTGATCGTCGCGGCGGCCGATGCCGACGCG
GCCGTGGCGGAACTGAGCGCCGCCGGCGAGCAGGTCTGGAAGATCGGCAAGGTGCGCGCCACGCGCGAGGGCGAGGCGCA
GACCGTGGTGGTCTGA

Upstream 100 bases:

>100_bases
TCGGACACGATGCGTTACCTGGAGAGATCGGCGCGGGGAATTCGGCCGGGCGTCCGGCTTCGGGTAAAATCGCATTTTAC
CGACCTTCTCGCATTCCCCC

Downstream 100 bases:

>100_bases
GGCTGGCGCAGCAGGAGGATCGGTGGCACGGCGCTCGTGCCGTGCAGCAGGAAGGGCCGCGGAGCGCGGCCTTTTTTGTT
GCCTGGCGCGGACGCGTTCA

Product: phosphoribosylaminoimidazole synthetase

Products: NA

Alternate protein names: AIR synthase; AIRS; Phosphoribosyl-aminoimidazole synthetase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTSPKSAPDAQGLSYRDAGVDIDAGDALVDKIKPFAKKTLRDGVLGGIGGFGALFEVPKKYREPVLVSGTDGVGTKLKLA
FHLNRHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKLDVETAATVVKGIATGCELAGCALIGGETAEMPGMYPDGEY
DLAGFAVGAVEKSRIIDGSTIAAGDVVLGLASSGIHSNGFSLVRKIIERANPDLDAAFDGRTLADALIAPTRIYVKPLLA
LMAKLPVKGMAHITGGGLVENIPRVLREGLTAELDQTAWTLPPLFQWLQQHGGVADAEMHRVFNCGIGMAVIVAAADADA
AVAELSAAGEQVWKIGKVRATREGEAQTVVV

Sequences:

>Translated_351_residues
MTSPKSAPDAQGLSYRDAGVDIDAGDALVDKIKPFAKKTLRDGVLGGIGGFGALFEVPKKYREPVLVSGTDGVGTKLKLA
FHLNRHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKLDVETAATVVKGIATGCELAGCALIGGETAEMPGMYPDGEY
DLAGFAVGAVEKSRIIDGSTIAAGDVVLGLASSGIHSNGFSLVRKIIERANPDLDAAFDGRTLADALIAPTRIYVKPLLA
LMAKLPVKGMAHITGGGLVENIPRVLREGLTAELDQTAWTLPPLFQWLQQHGGVADAEMHRVFNCGIGMAVIVAAADADA
AVAELSAAGEQVWKIGKVRATREGEAQTVVV
>Mature_350_residues
TSPKSAPDAQGLSYRDAGVDIDAGDALVDKIKPFAKKTLRDGVLGGIGGFGALFEVPKKYREPVLVSGTDGVGTKLKLAF
HLNRHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKLDVETAATVVKGIATGCELAGCALIGGETAEMPGMYPDGEYD
LAGFAVGAVEKSRIIDGSTIAAGDVVLGLASSGIHSNGFSLVRKIIERANPDLDAAFDGRTLADALIAPTRIYVKPLLAL
MAKLPVKGMAHITGGGLVENIPRVLREGLTAELDQTAWTLPPLFQWLQQHGGVADAEMHRVFNCGIGMAVIVAAADADAA
VAELSAAGEQVWKIGKVRATREGEAQTVVV

Specific function: De novo purine biosynthesis; fifth step. [C]

COG id: COG0150

COG function: function code F; Phosphoribosylaminoimidazole (AIR) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR synthase family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=346, Percent_Identity=54.0462427745665, Blast_Score=368, Evalue=1e-102,
Organism=Homo sapiens, GI209869995, Length=346, Percent_Identity=54.0462427745665, Blast_Score=368, Evalue=1e-102,
Organism=Homo sapiens, GI209869993, Length=346, Percent_Identity=54.0462427745665, Blast_Score=368, Evalue=1e-102,
Organism=Escherichia coli, GI1788845, Length=343, Percent_Identity=60.0583090379009, Blast_Score=417, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17567511, Length=345, Percent_Identity=44.9275362318841, Blast_Score=267, Evalue=8e-72,
Organism=Saccharomyces cerevisiae, GI6321203, Length=335, Percent_Identity=49.5522388059701, Blast_Score=323, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24582400, Length=303, Percent_Identity=44.5544554455446, Blast_Score=255, Evalue=4e-68,

Paralogues:

None

Copy number: 180 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR004733
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.3.1 [H]

Molecular weight: Translated: 36652; Mature: 36520

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPKSAPDAQGLSYRDAGVDIDAGDALVDKIKPFAKKTLRDGVLGGIGGFGALFEVPKK
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YREPVLVSGTDGVGTKLKLAFHLNRHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKL
HCCCEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHCCCC
DVETAATVVKGIATGCELAGCALIGGETAEMPGMYPDGEYDLAGFAVGAVEKSRIIDGST
CHHHHHHHHHHHHCCCHHHCEEEECCCCCCCCCCCCCCCCCCHHEEECCHHHHHCCCCCC
IAAGDVVLGLASSGIHSNGFSLVRKIIERANPDLDAAFDGRTLADALIAPTRIYVKPLLA
EECCHHHEEHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHH
LMAKLPVKGMAHITGGGLVENIPRVLREGLTAELDQTAWTLPPLFQWLQQHGGVADAEMH
HHHHCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHH
RVFNCGIGMAVIVAAADADAAVAELSAAGEQVWKIGKVRATREGEAQTVVV
HHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEC
>Mature Secondary Structure 
TSPKSAPDAQGLSYRDAGVDIDAGDALVDKIKPFAKKTLRDGVLGGIGGFGALFEVPKK
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
YREPVLVSGTDGVGTKLKLAFHLNRHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKL
HCCCEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHCCCC
DVETAATVVKGIATGCELAGCALIGGETAEMPGMYPDGEYDLAGFAVGAVEKSRIIDGST
CHHHHHHHHHHHHCCCHHHCEEEECCCCCCCCCCCCCCCCCCHHEEECCHHHHHCCCCCC
IAAGDVVLGLASSGIHSNGFSLVRKIIERANPDLDAAFDGRTLADALIAPTRIYVKPLLA
EECCHHHEEHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHH
LMAKLPVKGMAHITGGGLVENIPRVLREGLTAELDQTAWTLPPLFQWLQQHGGVADAEMH
HHHHCCCCCEEEECCCHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHCCCCHHHHH
RVFNCGIGMAVIVAAADADAAVAELSAAGEQVWKIGKVRATREGEAQTVVV
HHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA