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The map label for this gene is pyrC [H]

Identifier: 238026233

GI number: 238026233

Start: 595720

End: 596790

Strand: Direct

Name: pyrC [H]

Synonym: bglu_1g05640

Alternate gene names: 238026233

Gene position: 595720-596790 (Clockwise)

Preceding gene: 238026231

Following gene: 238026234

Centisome position: 15.25

GC content: 71.06

Gene sequence:

>1071_bases
ATGACCGCTCCGAACGCCTCCGCCGCCCCCGTCACCTCGCTGACCCTCGCCCGTCCCGACGACTGGCACCTGCACGTGCG
CGACGGCGCGATGCTGGCCGCCGTGCTGCCGCACACGGCGCGCCAGTTCGGCCGCGCCATCATCATGCCGAACCTGAAGC
CGCCCGTGACCACCACGGCGCAGGCCGAGGCGTACCGCGCGCGGATCCTCGCCGCGCTGCCGGCCGGCATGGCCTTCGAG
CCGCTGATGACGCTCTACCTGACCGACAACACGCCGGCCGACGAGATCCGCCGCGCGCGAGAAAGCGGCTTCGTGCACGG
CGTGAAGCTCTATCCGGCCGGCGCGACGACCAACTCCGACGCCGGCGTGACGGACCTGGGCAAATGTTCGGGCGCGCTCG
AGGCGATGCAGGAAACCGGCATGCCGCTGCTGGTCCACGGCGAGGTCACGAATGCCGAGATCGACCTGTTCGATCGCGAG
AAGGTGTTCATCGATCGCGTGATGACGCCGCTGCGCCGCGATTTCCCGGCGCTCAAGGTGGTGTTCGAGCACATCACGAC
GAAGGACGCGGCCGACTACGTGCGCGACGCCGACGCGGCGCCCGGCATGCTCGGCGCGACCATCACCGCCCATCACCTGC
TCTACAACCGCAACGCGATCTTCACGGGCGGGATCCGGCCGCATTACTACTGTCTGCCGGTGCTCAAGCGCGAGACGCAC
CGCGTGGCGCTGGTGGCGGCGGCGACCTCCGGCAACGCGCGCTTCTTCCTCGGCACCGACAGCGCCCCGCACGCACAGGG
CGCCAAGGAAGCGGCCTGCGGCTGCGCCGGCTGCTACACGGCGCTGCACGCGCTCGAACTCTACGCGGAAGCGTTCGACC
AGGCCGGCGCGCTCGACAAGCTGGAGGGCTTCGCGAGCTTCTTCGGCGCCGATTTCTACGGCCTGCCGCGCGCCACCGAG
ACGGTCACGCTGCGTCGCGAGACCTGGCAGTTGCCGGCCACCGTCGAGGCCGGCGACACCGCGGTCGTGCCGCTGCGCGG
CGGCGAGCCGATCGGCTGGCGCCTGGTGTGA

Upstream 100 bases:

>100_bases
GCGGTTCCCTGTTGCGGTTTTCCGTCACTCGCGACGGGCCGCGGGACGGCGGGCGCCGCGGCCCGCGCGCGCCGCCGCCC
GCCCACCCGACGACGCCCCA

Downstream 100 bases:

>100_bases
GCGGTGCCGCGCGGGGCCCGTCCGGCGCCGGCTTTGCGGCGATCGACTGGCAACTGCCGTGGCTCGCACCGTTCGCGGCG
CGCGGGCCGCGCTGGCAGGC

Product: dihydroorotase

Products: NA

Alternate protein names: DHOase [H]

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTAPNASAAPVTSLTLARPDDWHLHVRDGAMLAAVLPHTARQFGRAIIMPNLKPPVTTTAQAEAYRARILAALPAGMAFE
PLMTLYLTDNTPADEIRRARESGFVHGVKLYPAGATTNSDAGVTDLGKCSGALEAMQETGMPLLVHGEVTNAEIDLFDRE
KVFIDRVMTPLRRDFPALKVVFEHITTKDAADYVRDADAAPGMLGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETH
RVALVAAATSGNARFFLGTDSAPHAQGAKEAACGCAGCYTALHALELYAEAFDQAGALDKLEGFASFFGADFYGLPRATE
TVTLRRETWQLPATVEAGDTAVVPLRGGEPIGWRLV

Sequences:

>Translated_356_residues
MTAPNASAAPVTSLTLARPDDWHLHVRDGAMLAAVLPHTARQFGRAIIMPNLKPPVTTTAQAEAYRARILAALPAGMAFE
PLMTLYLTDNTPADEIRRARESGFVHGVKLYPAGATTNSDAGVTDLGKCSGALEAMQETGMPLLVHGEVTNAEIDLFDRE
KVFIDRVMTPLRRDFPALKVVFEHITTKDAADYVRDADAAPGMLGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETH
RVALVAAATSGNARFFLGTDSAPHAQGAKEAACGCAGCYTALHALELYAEAFDQAGALDKLEGFASFFGADFYGLPRATE
TVTLRRETWQLPATVEAGDTAVVPLRGGEPIGWRLV
>Mature_355_residues
TAPNASAAPVTSLTLARPDDWHLHVRDGAMLAAVLPHTARQFGRAIIMPNLKPPVTTTAQAEAYRARILAALPAGMAFEP
LMTLYLTDNTPADEIRRARESGFVHGVKLYPAGATTNSDAGVTDLGKCSGALEAMQETGMPLLVHGEVTNAEIDLFDREK
VFIDRVMTPLRRDFPALKVVFEHITTKDAADYVRDADAAPGMLGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETHR
VALVAAATSGNARFFLGTDSAPHAQGAKEAACGCAGCYTALHALELYAEAFDQAGALDKLEGFASFFGADFYGLPRATET
VTLRRETWQLPATVEAGDTAVVPLRGGEPIGWRLV

Specific function: Pyrimidine biosynthesis; third step. [C]

COG id: COG0418

COG function: function code F; Dihydroorotase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787301, Length=347, Percent_Identity=54.4668587896254, Blast_Score=381, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6323452, Length=366, Percent_Identity=34.6994535519126, Blast_Score=191, Evalue=1e-49,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR004721
- InterPro:   IPR002195 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.3 [H]

Molecular weight: Translated: 38284; Mature: 38153

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00482 DIHYDROOROTASE_1 ; PS00483 DIHYDROOROTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPNASAAPVTSLTLARPDDWHLHVRDGAMLAAVLPHTARQFGRAIIMPNLKPPVTTTA
CCCCCCCCCCCEEEEEECCCCCEEEEECCCEEEHHHHHHHHHHCCEEECCCCCCCCCCCH
QAEAYRARILAALPAGMAFEPLMTLYLTDNTPADEIRRARESGFVHGVKLYPAGATTNSD
HHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCCCCC
AGVTDLGKCSGALEAMQETGMPLLVHGEVTNAEIDLFDREKVFIDRVMTPLRRDFPALKV
CCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCHHHHHHHHHHHHHHCCHHHHH
VFEHITTKDAADYVRDADAAPGMLGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETH
HHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHHEECCCEEEECCCCCCEEEEEHHHCCCC
RVALVAAATSGNARFFLGTDSAPHAQGAKEAACGCAGCYTALHALELYAEAFDQAGALDK
EEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LEGFASFFGADFYGLPRATETVTLRRETWQLPATVEAGDTAVVPLRGGEPIGWRLV
HHHHHHHHCCCCCCCCCCCEEEEEEHHHCCCCEEEECCCEEEEEECCCCCCCCEEC
>Mature Secondary Structure 
TAPNASAAPVTSLTLARPDDWHLHVRDGAMLAAVLPHTARQFGRAIIMPNLKPPVTTTA
CCCCCCCCCCEEEEEECCCCCEEEEECCCEEEHHHHHHHHHHCCEEECCCCCCCCCCCH
QAEAYRARILAALPAGMAFEPLMTLYLTDNTPADEIRRARESGFVHGVKLYPAGATTNSD
HHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCCCCC
AGVTDLGKCSGALEAMQETGMPLLVHGEVTNAEIDLFDREKVFIDRVMTPLRRDFPALKV
CCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCHHHHHHHHHHHHHHCCHHHHH
VFEHITTKDAADYVRDADAAPGMLGATITAHHLLYNRNAIFTGGIRPHYYCLPVLKRETH
HHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHHEECCCEEEECCCCCCEEEEEHHHCCCC
RVALVAAATSGNARFFLGTDSAPHAQGAKEAACGCAGCYTALHALELYAEAFDQAGALDK
EEEEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LEGFASFFGADFYGLPRATETVTLRRETWQLPATVEAGDTAVVPLRGGEPIGWRLV
HHHHHHHHCCCCCCCCCCCEEEEEEHHHCCCCEEEECCCEEEEEECCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA