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The map label for this gene is gltK [H]

Identifier: 238026230

GI number: 238026230

Start: 593069

End: 593746

Strand: Direct

Name: gltK [H]

Synonym: bglu_1g05610

Alternate gene names: 238026230

Gene position: 593069-593746 (Clockwise)

Preceding gene: 238026229

Following gene: 238026231

Centisome position: 15.18

GC content: 64.75

Gene sequence:

>678_bases
ATGCACGACTTCGACTGGAGTGGGATTCCCGGCGCGCTGCCCGCGCTGTGGACGGGGGCGATCGTCACGCTCGAGATCAC
CGCGCTCGCGATCGTGGTCGGCATCGTATGGGGCACGCTGCTCGCGCTGATGCGGCTGTCGGGCGTCGCCGCGCTGCAAT
GGTTCGCGCGGCTCTACGTGACGGTGTTCCGTTCCATCCCGCTGGTGATGGTGCTGCTATGGTTCTTCCTGATCGTGCCG
CAACTGCTGCAGGGCGTGCTCGGGCTGTCGCCGACCATCGACATCCGGCTCGCCTCGGCGATGATCGCGTTCTCGTTGTT
CGAGGCTGCGTATTATTCGGAGATCATTCGCGCGGGGATTCAGGCGGTGCCGCGCGGGCAGGTCAACGCGGCGTTCGCGC
TCGGCATGGGCTACGGCCAGGCGATGCGCCTCGTGATCCTGCCGCAGGCGTTTCGCGCGATGGTGCCGCTGCTGCTCACG
CAGGCGATCGTGCTGTTCCAGGACACCTCGCTCGTCTATGTGATCAGCCTCGCGGACTTCTTCCGCACGGCCACCAACAT
CGGCGATCGCGACGGCACCAGCGTCGAGATGATCCTGTTCGCGGGCGCCTGCTATTTCGTCGTGTGCGTGCTGGCTTCCG
CACTCGTCAAGGGTCTTCAGAAAAAGGTTACAAGATGA

Upstream 100 bases:

>100_bases
CCGTCACGCTCGCCTACGTGATCATCAACCTCGTCGTGATGGCCCTGATGCGCTGGATCGAATCCAGGACGCGGCTGCCC
GGCTATATCGGAGGCAAGTG

Downstream 100 bases:

>100_bases
TTTCCATCAAGAACGTCTCGAAGTGGTATGGGCAGTTCCAGGTGCTGACCGACTGCACGACGGAGGTGAAGAAGGGCGAG
GTGGTGGTGGTGTGCGGGCC

Product: glutamate/aspartate transport system permease

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MHDFDWSGIPGALPALWTGAIVTLEITALAIVVGIVWGTLLALMRLSGVAALQWFARLYVTVFRSIPLVMVLLWFFLIVP
QLLQGVLGLSPTIDIRLASAMIAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMGYGQAMRLVILPQAFRAMVPLLLT
QAIVLFQDTSLVYVISLADFFRTATNIGDRDGTSVEMILFAGACYFVVCVLASALVKGLQKKVTR

Sequences:

>Translated_225_residues
MHDFDWSGIPGALPALWTGAIVTLEITALAIVVGIVWGTLLALMRLSGVAALQWFARLYVTVFRSIPLVMVLLWFFLIVP
QLLQGVLGLSPTIDIRLASAMIAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMGYGQAMRLVILPQAFRAMVPLLLT
QAIVLFQDTSLVYVISLADFFRTATNIGDRDGTSVEMILFAGACYFVVCVLASALVKGLQKKVTR
>Mature_225_residues
MHDFDWSGIPGALPALWTGAIVTLEITALAIVVGIVWGTLLALMRLSGVAALQWFARLYVTVFRSIPLVMVLLWFFLIVP
QLLQGVLGLSPTIDIRLASAMIAFSLFEAAYYSEIIRAGIQAVPRGQVNAAFALGMGYGQAMRLVILPQAFRAMVPLLLT
QAIVLFQDTSLVYVISLADFFRTATNIGDRDGTSVEMILFAGACYFVVCVLASALVKGLQKKVTR

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=69.8198198198198, Blast_Score=314, Evalue=3e-87,
Organism=Escherichia coli, GI1788226, Length=214, Percent_Identity=36.9158878504673, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI87082239, Length=210, Percent_Identity=35.7142857142857, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786874, Length=187, Percent_Identity=32.620320855615, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787030, Length=222, Percent_Identity=28.8288288288288, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788645, Length=217, Percent_Identity=26.7281105990783, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787087, Length=224, Percent_Identity=27.2321428571429, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI48994930, Length=129, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788646, Length=215, Percent_Identity=27.4418604651163, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787086, Length=214, Percent_Identity=26.1682242990654, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24446; Mature: 24446

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDFDWSGIPGALPALWTGAIVTLEITALAIVVGIVWGTLLALMRLSGVAALQWFARLYV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVFRSIPLVMVLLWFFLIVPQLLQGVLGLSPTIDIRLASAMIAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVPRGQVNAAFALGMGYGQAMRLVILPQAFRAMVPLLLTQAIVLFQDTSLVYVISLADF
HHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FRTATNIGDRDGTSVEMILFAGACYFVVCVLASALVKGLQKKVTR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHDFDWSGIPGALPALWTGAIVTLEITALAIVVGIVWGTLLALMRLSGVAALQWFARLYV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TVFRSIPLVMVLLWFFLIVPQLLQGVLGLSPTIDIRLASAMIAFSLFEAAYYSEIIRAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVPRGQVNAAFALGMGYGQAMRLVILPQAFRAMVPLLLTQAIVLFQDTSLVYVISLADF
HHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FRTATNIGDRDGTSVEMILFAGACYFVVCVLASALVKGLQKKVTR
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]