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The map label for this gene is exbB [H]

Identifier: 238026213

GI number: 238026213

Start: 572984

End: 573673

Strand: Direct

Name: exbB [H]

Synonym: bglu_1g05440

Alternate gene names: 238026213

Gene position: 572984-573673 (Clockwise)

Preceding gene: 238026212

Following gene: 238026214

Centisome position: 14.67

GC content: 75.8

Gene sequence:

>690_bases
ATGGCCACCGATACCGGCGTCATCCACTATCTCGCGAGCGGCGATGCCGTCACGCATGCCGTCGCGTACCTGCTGCTGGC
GATGTCGGTGGCGAGCTGGTGCTGCCTGCTGCTCAAGGCGTGGACGCTGGTGCGCGCGAGGCGTGCGAGCGCCGGCGCGA
TCGCCGCGTTCTGGCGGGCCGGCTCGTTCGACGCGGGGCTCGCCGCGCTGCGCGCCGCCGACCGCGAGCGCGTGTTCGTG
CCGCTCGCGGCCGCCGCCGACGCGGCGGCGCGGGAGGCCGCCGCCGGCGCGGCGCTGCTGGGCGCGCGCGTTGCGCCCGG
CGAACGCGTGCTGCGGGCGGTGCGCGAGGCCATGCGCGGCTCGCAGCGGCGGCTCGAGTTCGGCCTCGTGCTGCTCGCCT
CGATCGCCAGCACGGCGCCGTTCGTCGGACTGCTCGGCACGGTCTGGGGCATCTACCACGCGCTCGGCAGCATCGCCGCG
AGCGGTCAGGCGCAGATCGGCAGCGTGGCCGGCCCGGTCGGCGAGGCGCTGATCATGACCGCGTTCGGGCTGGTGGTCGC
GATTCCGGCGGTGCTCGCCTACAACATGCTCGGCCGCCTGGTGCGGCAGCTCGTCGAGGATCTCGACGGGTTCGCGCGCG
ACCTGCACGCATTCGCCGGCGGCGCGCCCGAGCGCGACGCGCGGGCCTGA

Upstream 100 bases:

>100_bases
CGCGGTGCGCTTCCTCGCCGACAAGCCGAGCGGCCTGTTCGACATGCAGGACGTGCTCGGCCTGCGCTGAGCAGGCCGGC
CGATCGATCCGGAGCCGCGC

Downstream 100 bases:

>100_bases
GGGCGCACCGTGGCATTCGGCGGACTCGATCCTCGCGAACCGGCCGCGCCGATGGCCGAGATCAACATGACGCCGCTGAT
CGACGTGATGCTGGTGCTGC

Product: MotA/TolQ/ExbB proton channel family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MATDTGVIHYLASGDAVTHAVAYLLLAMSVASWCCLLLKAWTLVRARRASAGAIAAFWRAGSFDAGLAALRAADRERVFV
PLAAAADAAAREAAAGAALLGARVAPGERVLRAVREAMRGSQRRLEFGLVLLASIASTAPFVGLLGTVWGIYHALGSIAA
SGQAQIGSVAGPVGEALIMTAFGLVVAIPAVLAYNMLGRLVRQLVEDLDGFARDLHAFAGGAPERDARA

Sequences:

>Translated_229_residues
MATDTGVIHYLASGDAVTHAVAYLLLAMSVASWCCLLLKAWTLVRARRASAGAIAAFWRAGSFDAGLAALRAADRERVFV
PLAAAADAAAREAAAGAALLGARVAPGERVLRAVREAMRGSQRRLEFGLVLLASIASTAPFVGLLGTVWGIYHALGSIAA
SGQAQIGSVAGPVGEALIMTAFGLVVAIPAVLAYNMLGRLVRQLVEDLDGFARDLHAFAGGAPERDARA
>Mature_228_residues
ATDTGVIHYLASGDAVTHAVAYLLLAMSVASWCCLLLKAWTLVRARRASAGAIAAFWRAGSFDAGLAALRAADRERVFVP
LAAAADAAAREAAAGAALLGARVAPGERVLRAVREAMRGSQRRLEFGLVLLASIASTAPFVGLLGTVWGIYHALGSIAAS
GQAQIGSVAGPVGEALIMTAFGLVVAIPAVLAYNMLGRLVRQLVEDLDGFARDLHAFAGGAPERDARA

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=228, Percent_Identity=29.8245614035088, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789381, Length=216, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 23591; Mature: 23459

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDTGVIHYLASGDAVTHAVAYLLLAMSVASWCCLLLKAWTLVRARRASAGAIAAFWRA
CCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
GSFDAGLAALRAADRERVFVPLAAAADAAAREAAAGAALLGARVAPGERVLRAVREAMRG
CCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
SQRRLEFGLVLLASIASTAPFVGLLGTVWGIYHALGSIAASGQAQIGSVAGPVGEALIMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AFGLVVAIPAVLAYNMLGRLVRQLVEDLDGFARDLHAFAGGAPERDARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ATDTGVIHYLASGDAVTHAVAYLLLAMSVASWCCLLLKAWTLVRARRASAGAIAAFWRA
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHC
GSFDAGLAALRAADRERVFVPLAAAADAAAREAAAGAALLGARVAPGERVLRAVREAMRG
CCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
SQRRLEFGLVLLASIASTAPFVGLLGTVWGIYHALGSIAASGQAQIGSVAGPVGEALIMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
AFGLVVAIPAVLAYNMLGRLVRQLVEDLDGFARDLHAFAGGAPERDARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9140974 [H]