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The map label for this gene is tkt1 [H]

Identifier: 238026204

GI number: 238026204

Start: 563173

End: 565194

Strand: Direct

Name: tkt1 [H]

Synonym: bglu_1g05350

Alternate gene names: 238026204

Gene position: 563173-565194 (Clockwise)

Preceding gene: 238026200

Following gene: 238026205

Centisome position: 14.42

GC content: 67.85

Gene sequence:

>2022_bases
ATGACGACCTCGTCTACCGCCAGCACCTCCCTGATGGCCAATGCGATTCGCGCCCTCGCGATGGATGCCGTCCAGCAAGC
CAACTCCGGCCACCCTGGCATGCCGATGGGCATGGCCGAGATCGGCGTGGCCCTGTGGTCGCGCCATCTGAAGCACAACC
CGGCGAACCCGCACTGGGCCGATCGCGACCGCTTCGTGCTGTCGAACGGCCATGGCTCGATGCTGCTGTACTCGCTGCTG
CACCTGACCGGCTATGACCTGCCGATCGAGGAGCTGAAGAACTTCCGCCAGTTGCACTCGAAGACGCCGGGCCACCCGGA
ATACGGCATCACGGCCGGCGTCGAGACCACCACCGGCCCGCTCGGCCAGGGTCTCGCGAATGCGGTCGGCATGGCGCTCG
CCGAGGCGCTGCTCGCCGCCGAGTTCAACAAGGACGGCGCGACGATCGTCGATCACCACACCTACGTGTTCCTCGGCGAC
GGCTGCCTGATGGAAGGCATCTCGCACGAGGCGTGCTCGTTCGCCGGCACGCTGAAGCTGAACAAGCTGATCGCGCTCTA
CGACGACAACGGCATCTCGATCGACGGCGACGTGGTCAACTGGTTCCACGACGACACCCCGAAGCGTTTCGAAGCCTACG
GCTGGAACGTGATTCCGGGCGTGGACGGCCATGACGTCGACGCCGTCGACGCGGCGATCGCGAAGGCGAAGCTGTCGGAC
AAGCCGACGCTGATCTGCTGCAAGACCGTGATCGGCAAGGGCGCGGCGACCAAGGCCGGCGGCCACGACGTGCACGGCGC
GGCGCTCGGCGCCGAGGAGATCGCCAAGACGCGCGCGGCGCTCGGCTGGAACTGGGAGCCGTTCGTGATCCCGCAGGAAG
TCTATGCGGCGTGGGACGGCAAGGCGGCCGGCGCGAAGCGCGAAAGCGACTGGAACGCCGTGTTCGAGGCCTACCGCGCG
AAGTTCCCGGCCGAGGCCGACGAGTTCGTGCGCCGCATGGCGGGCAAGCTGCCGGCCGACTGGGCGCAGAAGGCCGCCGC
GATCGTGGCCGGCGCGAACGAGCGCGGCGAGACGGTGGCCACGCGCAAGGCTTCGCAGCAGACCATCGAGGGCCTCGCCG
CCGCGCTGCCCGAGCTGATCGGCGGCTCGGCCGACCTGACCGGCTCGAACCTGACGAACTGGAAGGCGTCGAAGCCGGTT
CGCGCGGGCGAGAAAGGCATTCAGTGGGGAAACCATATCAATTACGGCGTGCGCGAATTCGGCATGAGCGCCGCGATCAA
CGGTATCGTGCTTCATGGCGGCTACAAGCCTTTCGGCGGCACCTTCCTGACGTTCTCGGACTACAGCCGCAACGCGTTGC
GCGTGGCCGCGCTGATGAAGGCGCCCTCGCTGTTCGTGTTTACGCACGACTCGATCGGCCTCGGCGAGGACGGTCCGACG
CACCAGTCCATCGAGCACGTTTCGAGCCTGCGGCTGATTCCGCACCTCGATGTCTGGCGCCCGGCCGACACGGTCGAGAC
GGCCGTGGCCTGGACCGAGGCCGTTGCCGCGCAACGTCCGTCGTGCCTGATCTTCAGCCGCCAGAACCTGGCGTTCAACG
CGCGCAGCGACGCGCAGCTGGCGAACGTCGCCAAGGGCGGCTACGTGCTGCGCGACTGGGACGAGGAAGTCGTCGCCCGC
AAGATCATCCTGATCGCGACGGGCTCCGAGGTCGAGCTGGCGATGAAGGCCGTCGAGCCGCTCGCGCAGCAGGGCATCGC
CGCGCGCGTCGTGTCGATGCCGGCCACCACCGTGTTCGATCGTCAGGACGCCGAGTACCGTGAGCGCGTGCTGCCGGCCG
GCGTGCGCCGCGTCGCCATCGAGGCGGGCGTGACCGACTTCTGGCGCAAGTACGTCGGCCTCGAGGGCGGCGTGATCGGG
ATCGATTCGTTCGGCGAATCGGCTCCGGCCGGCGTACTCTTCAAGTATTTCGGCTTCACCATCGAGAACGTGGTCGAGAC
GGCGAAGCGCGTGCTCGCCTGA

Upstream 100 bases:

>100_bases
TCGCGTCCCCATGGCGCCGCATCGCGCGCCGGGAGCGGTCGGCCCGCGAGCTTCCGGACCAGCCGTGCCCCGTTTTCTCG
ACTCGTTCTCCGGACTCGAC

Downstream 100 bases:

>100_bases
GCGTGAGCCAGCGCGCCGGCTGCGCCTCGCCGGCGGGCCGGCGCCGTCGTGAAGCCGGCGATCCGTTTTTTTTCAGCCAT
CAGGAGATTAATCATGACGA

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MTTSSTASTSLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPANPHWADRDRFVLSNGHGSMLLYSLL
HLTGYDLPIEELKNFRQLHSKTPGHPEYGITAGVETTTGPLGQGLANAVGMALAEALLAAEFNKDGATIVDHHTYVFLGD
GCLMEGISHEACSFAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPGVDGHDVDAVDAAIAKAKLSD
KPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRAALGWNWEPFVIPQEVYAAWDGKAAGAKRESDWNAVFEAYRA
KFPAEADEFVRRMAGKLPADWAQKAAAIVAGANERGETVATRKASQQTIEGLAAALPELIGGSADLTGSNLTNWKASKPV
RAGEKGIQWGNHINYGVREFGMSAAINGIVLHGGYKPFGGTFLTFSDYSRNALRVAALMKAPSLFVFTHDSIGLGEDGPT
HQSIEHVSSLRLIPHLDVWRPADTVETAVAWTEAVAAQRPSCLIFSRQNLAFNARSDAQLANVAKGGYVLRDWDEEVVAR
KIILIATGSEVELAMKAVEPLAQQGIAARVVSMPATTVFDRQDAEYRERVLPAGVRRVAIEAGVTDFWRKYVGLEGGVIG
IDSFGESAPAGVLFKYFGFTIENVVETAKRVLA

Sequences:

>Translated_673_residues
MTTSSTASTSLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPANPHWADRDRFVLSNGHGSMLLYSLL
HLTGYDLPIEELKNFRQLHSKTPGHPEYGITAGVETTTGPLGQGLANAVGMALAEALLAAEFNKDGATIVDHHTYVFLGD
GCLMEGISHEACSFAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPGVDGHDVDAVDAAIAKAKLSD
KPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRAALGWNWEPFVIPQEVYAAWDGKAAGAKRESDWNAVFEAYRA
KFPAEADEFVRRMAGKLPADWAQKAAAIVAGANERGETVATRKASQQTIEGLAAALPELIGGSADLTGSNLTNWKASKPV
RAGEKGIQWGNHINYGVREFGMSAAINGIVLHGGYKPFGGTFLTFSDYSRNALRVAALMKAPSLFVFTHDSIGLGEDGPT
HQSIEHVSSLRLIPHLDVWRPADTVETAVAWTEAVAAQRPSCLIFSRQNLAFNARSDAQLANVAKGGYVLRDWDEEVVAR
KIILIATGSEVELAMKAVEPLAQQGIAARVVSMPATTVFDRQDAEYRERVLPAGVRRVAIEAGVTDFWRKYVGLEGGVIG
IDSFGESAPAGVLFKYFGFTIENVVETAKRVLA
>Mature_672_residues
TTSSTASTSLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPANPHWADRDRFVLSNGHGSMLLYSLLH
LTGYDLPIEELKNFRQLHSKTPGHPEYGITAGVETTTGPLGQGLANAVGMALAEALLAAEFNKDGATIVDHHTYVFLGDG
CLMEGISHEACSFAGTLKLNKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPGVDGHDVDAVDAAIAKAKLSDK
PTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRAALGWNWEPFVIPQEVYAAWDGKAAGAKRESDWNAVFEAYRAK
FPAEADEFVRRMAGKLPADWAQKAAAIVAGANERGETVATRKASQQTIEGLAAALPELIGGSADLTGSNLTNWKASKPVR
AGEKGIQWGNHINYGVREFGMSAAINGIVLHGGYKPFGGTFLTFSDYSRNALRVAALMKAPSLFVFTHDSIGLGEDGPTH
QSIEHVSSLRLIPHLDVWRPADTVETAVAWTEAVAAQRPSCLIFSRQNLAFNARSDAQLANVAKGGYVLRDWDEEVVARK
IILIATGSEVELAMKAVEPLAQQGIAARVVSMPATTVFDRQDAEYRERVLPAGVRRVAIEAGVTDFWRKYVGLEGGVIGI
DSFGESAPAGVLFKYFGFTIENVVETAKRVLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=598, Percent_Identity=29.2642140468227, Blast_Score=176, Evalue=9e-44,
Organism=Homo sapiens, GI4507521, Length=598, Percent_Identity=29.2642140468227, Blast_Score=176, Evalue=9e-44,
Organism=Homo sapiens, GI133778974, Length=587, Percent_Identity=27.0868824531516, Blast_Score=141, Evalue=2e-33,
Organism=Escherichia coli, GI48994911, Length=669, Percent_Identity=62.0328849028401, Blast_Score=855, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=664, Percent_Identity=59.9397590361446, Blast_Score=808, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=688, Percent_Identity=26.453488372093, Blast_Score=160, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6325331, Length=681, Percent_Identity=49.9265785609398, Blast_Score=617, Evalue=1e-177,
Organism=Saccharomyces cerevisiae, GI6319593, Length=674, Percent_Identity=46.2908011869436, Blast_Score=564, Evalue=1e-161,
Organism=Drosophila melanogaster, GI45551847, Length=684, Percent_Identity=26.7543859649123, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI45550715, Length=684, Percent_Identity=26.7543859649123, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24666278, Length=587, Percent_Identity=27.427597955707, Blast_Score=152, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24645119, Length=651, Percent_Identity=26.42089093702, Blast_Score=149, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72150; Mature: 72019

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSSTASTSLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPANPHWA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
DRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITAGVETTTGP
CCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCC
LGQGLANAVGMALAEALLAAEFNKDGATIVDHHTYVFLGDGCLMEGISHEACSFAGTLKL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHHCCCHHHHHHHHHEEE
NKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPGVDGHDVDAVDAAIAKAKLSD
EEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCCCHHHHHHHHHHHCCC
KPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRAALGWNWEPFVIPQEVYAAWDG
CCCEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCCEECHHHHHHHCCC
KAAGAKRESDWNAVFEAYRAKFPAEADEFVRRMAGKLPADWAQKAAAIVAGANERGETVA
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHEEECCCCCCCCHH
TRKASQQTIEGLAAALPELIGGSADLTGSNLTNWKASKPVRAGEKGIQWGNHINYGVREF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHH
GMSAAINGIVLHGGYKPFGGTFLTFSDYSRNALRVAALMKAPSLFVFTHDSIGLGEDGPT
CHHHHCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCC
HQSIEHVSSLRLIPHLDVWRPADTVETAVAWTEAVAAQRPSCLIFSRQNLAFNARSDAQL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCHHH
ANVAKGGYVLRDWDEEVVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPATTVFD
HHHHCCCEEEECCCHHHHHCEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHCCCHHEEC
RQDAEYRERVLPAGVRRVAIEAGVTDFWRKYVGLEGGVIGIDSFGESAPAGVLFKYFGFT
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHH
IENVVETAKRVLA
HHHHHHHHHHHCC
>Mature Secondary Structure 
TTSSTASTSLMANAIRALAMDAVQQANSGHPGMPMGMAEIGVALWSRHLKHNPANPHWA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
DRDRFVLSNGHGSMLLYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEYGITAGVETTTGP
CCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCC
LGQGLANAVGMALAEALLAAEFNKDGATIVDHHTYVFLGDGCLMEGISHEACSFAGTLKL
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCHHHHCCCHHHHHHHHHEEE
NKLIALYDDNGISIDGDVVNWFHDDTPKRFEAYGWNVIPGVDGHDVDAVDAAIAKAKLSD
EEEEEEECCCCCEECCCEEECCCCCCCCHHHHCCCEECCCCCCCCCHHHHHHHHHHHCCC
KPTLICCKTVIGKGAATKAGGHDVHGAALGAEEIAKTRAALGWNWEPFVIPQEVYAAWDG
CCCEEEEHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHHCCCCCCCEECHHHHHHHCCC
KAAGAKRESDWNAVFEAYRAKFPAEADEFVRRMAGKLPADWAQKAAAIVAGANERGETVA
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHEEECCCCCCCCHH
TRKASQQTIEGLAAALPELIGGSADLTGSNLTNWKASKPVRAGEKGIQWGNHINYGVREF
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHH
GMSAAINGIVLHGGYKPFGGTFLTFSDYSRNALRVAALMKAPSLFVFTHDSIGLGEDGPT
CHHHHCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCC
HQSIEHVSSLRLIPHLDVWRPADTVETAVAWTEAVAAQRPSCLIFSRQNLAFNARSDAQL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEECCCCCHHH
ANVAKGGYVLRDWDEEVVARKIILIATGSEVELAMKAVEPLAQQGIAARVVSMPATTVFD
HHHHCCCEEEECCCHHHHHCEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHCCCHHEEC
RQDAEYRERVLPAGVRRVAIEAGVTDFWRKYVGLEGGVIGIDSFGESAPAGVLFKYFGFT
CCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHH
IENVVETAKRVLA
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]