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The map label for this gene is aroE [H]

Identifier: 238026183

GI number: 238026183

Start: 542180

End: 543049

Strand: Direct

Name: aroE [H]

Synonym: bglu_1g05140

Alternate gene names: 238026183

Gene position: 542180-543049 (Clockwise)

Preceding gene: 238026182

Following gene: 238026184

Centisome position: 13.88

GC content: 74.83

Gene sequence:

>870_bases
ATGAGCGAATCCGTCCAGCATCCGGCCCCGCGCGACCGCTACGTCGTGATCGGCAATCCGATCGCGCACAGCAAGTCGCC
CGCGATCCACGCCCGCTTCGCCGCGCAGACCGGCGAGGCGGTCGACTACGCGCACCGCCTCGCGCCGCTCGACGGCTTCG
CGGCGTCGGTGCGCGAGTTCATCGCCGAGGGAGGGCGCGGCGCGAACGTGACCGTGCCGTTCAAGCTCGAGGCGCATGCG
CTCGCCGACACGCTGTCGCCGCGCGCGGCGGCGGCGGGCGCCGTCAACACCCTGCGCTTCGACGCCGACGGCGCGATCCA
CGGCGACAACACCGACGGTGCCGGCCTCGTGCGCGACATCGAGCACAATCTCGGCGTGTCGCTGGCCGGCGCGCGGATCC
TGCTGCTCGGCGCGGGCGGCGCCGCGCGCGGCGTGGTGCTGCCGATGCTCGATCGCGGCCCGCTGTCGATCACGATCTCG
AACCGCACCGCGAGCCGCGCCGAGCAGCTGGCCGGCCAGTTCATGCAGGCCGCGCACGACGCGGGCTGTGCGCTGGCGGG
CGGCGGCGCGGCGGTCGTCGAACGGCGTGCCTACGACGTGATCGTCAACGCCACGGCCGGCAGCCTGGATGCGGCGCTGC
CCGAGTGCGACCCGGCCGCGTTCGGCACCGGTACGCTCGCCTACGACATGATGTACGGCACGCAGCCGACCGTGTTCATG
CAGCACGCCGCCGCGCTCGGCGCGCGCACGGCCGACGGGCTCGGCATGCTGGTCGAGCAGGCCGCCGAGTCGTTCTGGCT
GTGGCGCGGCGTGCGTCCCGACGGCGCGCCCGTGCTGGCGGCGCTGCGCGATGCGCTCGCCGCGGCCTGA

Upstream 100 bases:

>100_bases
GAGGCCGGAGCGCCGGCCGCCGGCACCGATGCCGGTGCGGCTGGCAGCGGCGAGGGCGACACGAAATGAACCCGAACCGC
TCCTCGCGGGCGACGGCACG

Downstream 100 bases:

>100_bases
ATCCGGCGCCGGCATGGCCGGGCCGCGCGCATGGTGATCCCGTTCGGCACCGGCCGGACCCGCGCCGGCAGGCCTCGGGC
GCGCCGGCACGGGCTGGCGC

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSESVQHPAPRDRYVVIGNPIAHSKSPAIHARFAAQTGEAVDYAHRLAPLDGFAASVREFIAEGGRGANVTVPFKLEAHA
LADTLSPRAAAAGAVNTLRFDADGAIHGDNTDGAGLVRDIEHNLGVSLAGARILLLGAGGAARGVVLPMLDRGPLSITIS
NRTASRAEQLAGQFMQAAHDAGCALAGGGAAVVERRAYDVIVNATAGSLDAALPECDPAAFGTGTLAYDMMYGTQPTVFM
QHAAALGARTADGLGMLVEQAAESFWLWRGVRPDGAPVLAALRDALAAA

Sequences:

>Translated_289_residues
MSESVQHPAPRDRYVVIGNPIAHSKSPAIHARFAAQTGEAVDYAHRLAPLDGFAASVREFIAEGGRGANVTVPFKLEAHA
LADTLSPRAAAAGAVNTLRFDADGAIHGDNTDGAGLVRDIEHNLGVSLAGARILLLGAGGAARGVVLPMLDRGPLSITIS
NRTASRAEQLAGQFMQAAHDAGCALAGGGAAVVERRAYDVIVNATAGSLDAALPECDPAAFGTGTLAYDMMYGTQPTVFM
QHAAALGARTADGLGMLVEQAAESFWLWRGVRPDGAPVLAALRDALAAA
>Mature_288_residues
SESVQHPAPRDRYVVIGNPIAHSKSPAIHARFAAQTGEAVDYAHRLAPLDGFAASVREFIAEGGRGANVTVPFKLEAHAL
ADTLSPRAAAAGAVNTLRFDADGAIHGDNTDGAGLVRDIEHNLGVSLAGARILLLGAGGAARGVVLPMLDRGPLSITISN
RTASRAEQLAGQFMQAAHDAGCALAGGGAAVVERRAYDVIVNATAGSLDAALPECDPAAFGTGTLAYDMMYGTQPTVFMQ
HAAALGARTADGLGMLVEQAAESFWLWRGVRPDGAPVLAALRDALAAA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=278, Percent_Identity=47.4820143884892, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1787983, Length=271, Percent_Identity=29.520295202952, Blast_Score=100, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6320332, Length=168, Percent_Identity=34.5238095238095, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29636; Mature: 29505

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESVQHPAPRDRYVVIGNPIAHSKSPAIHARFAAQTGEAVDYAHRLAPLDGFAASVREF
CCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEHHCCCHHHHHHHHHCCCCHHHHHHHHH
IAEGGRGANVTVPFKLEAHALADTLSPRAAAAGAVNTLRFDADGAIHGDNTDGAGLVRDI
HHCCCCCCEEEEEEEECHHHHHHHCCCHHHHCCCCEEEEECCCCCEECCCCCCCHHHHHH
EHNLGVSLAGARILLLGAGGAARGVVLPMLDRGPLSITISNRTASRAEQLAGQFMQAAHD
HHHCCEEECCCEEEEEECCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHH
AGCALAGGGAAVVERRAYDVIVNATAGSLDAALPECDPAAFGTGTLAYDMMYGTQPTVFM
CCCEEECCCHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHH
QHAAALGARTADGLGMLVEQAAESFWLWRGVRPDGAPVLAALRDALAAA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SESVQHPAPRDRYVVIGNPIAHSKSPAIHARFAAQTGEAVDYAHRLAPLDGFAASVREF
CCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEHHCCCHHHHHHHHHCCCCHHHHHHHHH
IAEGGRGANVTVPFKLEAHALADTLSPRAAAAGAVNTLRFDADGAIHGDNTDGAGLVRDI
HHCCCCCCEEEEEEEECHHHHHHHCCCHHHHCCCCEEEEECCCCCEECCCCCCCHHHHHH
EHNLGVSLAGARILLLGAGGAARGVVLPMLDRGPLSITISNRTASRAEQLAGQFMQAAHD
HHHCCEEECCCEEEEEECCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHH
AGCALAGGGAAVVERRAYDVIVNATAGSLDAALPECDPAAFGTGTLAYDMMYGTQPTVFM
CCCEEECCCHHHHHHCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHH
QHAAALGARTADGLGMLVEQAAESFWLWRGVRPDGAPVLAALRDALAAA
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA