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The map label for this gene is ffh [H]

Identifier: 238026162

GI number: 238026162

Start: 519769

End: 521136

Strand: Reverse

Name: ffh [H]

Synonym: bglu_1g04920

Alternate gene names: 238026162

Gene position: 521136-519769 (Counterclockwise)

Preceding gene: 238026170

Following gene: 238026161

Centisome position: 13.34

GC content: 66.45

Gene sequence:

>1368_bases
ATGCTCGACAATCTCACCCAACGGATGGCGCGCGTCGTCAAGACGCTGCGCGGCGAAGCCCGTCTCACCGAAGCCAACAC
GCAGGAGATGCTGCGCGAGGTCCGGCTCGCGCTGCTCGAGGCCGACGTCGCGCTGCCCGTGGTCCGCGAGTTCATCGCGA
AGGTCAAGGAAAAGGCCCTCGGCGAGGAAGTGATCAGCTCGCTCTCGCCGGGTCAGGCACTCGTCGGCGTGGTGCAGAAG
GAGCTGACCGCCGTGATCGGCGGCGACTACGAGGGCAAGGCCGTCGAGCTGAACCTGGCCGTCACGCCGCCGGCGATCAT
CCTGATGGCCGGCCTGCAGGGCGCCGGCAAGACCACCACGGTCGGCAAGCTCGCCAAGCTGCTGCGCGAGAAGCAGAAGA
AGAAAGTCCTGACGGTCTCGTGCGACGTCTATCGCCCCGCCGCGATCGCGCAGCTGAAAACGGTCAGCGAGCAGGTCGGT
GCCGATTTCTTCCCCTCCACGCCGGAACAGAAGCCCGTCGAGATCGCGCGCGCCGCGCTCGACTGGGCGAGGCGCCATTA
TCACGACGTGCTGATCGTCGACACGGCCGGCCGGCTCGGCATCGACGAGGCGATGATGAAGGAGATCGCCGAGCTGCACG
CCGCGATCAATCCCGCCGAGACGCTGTTCGTGGTCGACGCGATGCTGGGCCAGGATGCCGTCAACACCGCGAAGGCGTTC
AACGACGCGCTGCCGCTCACCGGCGTGGTGCTGACCAAGCTCGACGGCGATTCGCGCGGCGGCGCGGCGCTGTCGGTGCG
CAGCATCACCGGCAAGCCGATCAAGTTCGTCGGCGTGGCCGAGAAGCTCGACGGGCTGGAAGTGTTCCATCCGGATCGGA
TGGCGAACCGGATCCTCGGCATGGGCGACATTCTCGCGCTGGTTGAGGAGGCGCAGCGCGGCGTTGACGTGCAGGCCGCG
CAGAAGCTCGCCGACAAGGTCAAGAAAGGCGGCGACTTCGACCTCAACGATTTCCGCGCGCAGATCTCGCAGATGAAGAA
CATGGGCGGCCTGTCGTCGCTGATGGACAAGCTGCCCGCGCAATTCCAGCAGGCCGCCGCGGGCGCCGACATGGGCCACG
CCGAGAAGCAGATCCGCCGCATGGAGGGCATCATCAACTCGATGACGCCGGCCGAACGCGCCAAGCCCGACCTGATCAAG
GCCACCCGCAAGCGCCGCATCGCGGCCGGCGCGGGCGTGCCGGTGCAGGAAGTCAACCGGATGCTGAACCAGTACGATCA
GATGCGCACGATGATGAAGAAGCTCAAGGGCGGCAACATGCAGAAGATGATGCGCGGTCTCAAGGGCATGATGCCCGGCC
TGCGTTAA

Upstream 100 bases:

>100_bases
GTACAATATCCATGTTCGAAGTTTACACTAGGCCCCTTGCACGCGACGGCTGTCAATATATAGCACGCGCGCCTTCGGGC
CCCACTGTCCATCGCTCCCC

Downstream 100 bases:

>100_bases
TTTTTCGACGCCCCACGCGGCGCGGTGCACGGTATATCCTAATGGCGCATCGCCCGCTGCCCCGCATTGTCGGGGCGCCC
CGCCGCGAGTCCATTCACCG

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVALPVVREFIAKVKEKALGEEVISSLSPGQALVGVVQK
ELTAVIGGDYEGKAVELNLAVTPPAIILMAGLQGAGKTTTVGKLAKLLREKQKKKVLTVSCDVYRPAAIAQLKTVSEQVG
ADFFPSTPEQKPVEIARAALDWARRHYHDVLIVDTAGRLGIDEAMMKEIAELHAAINPAETLFVVDAMLGQDAVNTAKAF
NDALPLTGVVLTKLDGDSRGGAALSVRSITGKPIKFVGVAEKLDGLEVFHPDRMANRILGMGDILALVEEAQRGVDVQAA
QKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPAQFQQAAAGADMGHAEKQIRRMEGIINSMTPAERAKPDLIK
ATRKRRIAAGAGVPVQEVNRMLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGLR

Sequences:

>Translated_455_residues
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVALPVVREFIAKVKEKALGEEVISSLSPGQALVGVVQK
ELTAVIGGDYEGKAVELNLAVTPPAIILMAGLQGAGKTTTVGKLAKLLREKQKKKVLTVSCDVYRPAAIAQLKTVSEQVG
ADFFPSTPEQKPVEIARAALDWARRHYHDVLIVDTAGRLGIDEAMMKEIAELHAAINPAETLFVVDAMLGQDAVNTAKAF
NDALPLTGVVLTKLDGDSRGGAALSVRSITGKPIKFVGVAEKLDGLEVFHPDRMANRILGMGDILALVEEAQRGVDVQAA
QKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPAQFQQAAAGADMGHAEKQIRRMEGIINSMTPAERAKPDLIK
ATRKRRIAAGAGVPVQEVNRMLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGLR
>Mature_455_residues
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVALPVVREFIAKVKEKALGEEVISSLSPGQALVGVVQK
ELTAVIGGDYEGKAVELNLAVTPPAIILMAGLQGAGKTTTVGKLAKLLREKQKKKVLTVSCDVYRPAAIAQLKTVSEQVG
ADFFPSTPEQKPVEIARAALDWARRHYHDVLIVDTAGRLGIDEAMMKEIAELHAAINPAETLFVVDAMLGQDAVNTAKAF
NDALPLTGVVLTKLDGDSRGGAALSVRSITGKPIKFVGVAEKLDGLEVFHPDRMANRILGMGDILALVEEAQRGVDVQAA
QKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPAQFQQAAAGADMGHAEKQIRRMEGIINSMTPAERAKPDLIK
ATRKRRIAAGAGVPVQEVNRMLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGLR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=458, Percent_Identity=30.7860262008734, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI226371618, Length=397, Percent_Identity=30.9823677581864, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI89061728, Length=165, Percent_Identity=34.5454545454545, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI23308697, Length=202, Percent_Identity=33.1683168316832, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI295424842, Length=202, Percent_Identity=33.1683168316832, Blast_Score=100, Evalue=5e-21,
Organism=Escherichia coli, GI1788963, Length=452, Percent_Identity=64.8230088495575, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1789874, Length=278, Percent_Identity=33.0935251798561, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17539958, Length=461, Percent_Identity=28.6334056399132, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI193206261, Length=202, Percent_Identity=35.6435643564356, Blast_Score=99, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6325345, Length=423, Percent_Identity=31.2056737588652, Blast_Score=187, Evalue=3e-48,
Organism=Drosophila melanogaster, GI17647949, Length=448, Percent_Identity=29.9107142857143, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24641198, Length=271, Percent_Identity=29.1512915129151, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49306; Mature: 49306

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVALPVVREFIAKVKEKAL
CCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEEVISSLSPGQALVGVVQKELTAVIGGDYEGKAVELNLAVTPPAIILMAGLQGAGKTTT
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHCCCCCCCCHH
VGKLAKLLREKQKKKVLTVSCDVYRPAAIAQLKTVSEQVGADFFPSTPEQKPVEIARAAL
HHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
DWARRHYHDVLIVDTAGRLGIDEAMMKEIAELHAAINPAETLFVVDAMLGQDAVNTAKAF
HHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHH
NDALPLTGVVLTKLDGDSRGGAALSVRSITGKPIKFVGVAEKLDGLEVFHPDRMANRILG
HCCCCHHHEEEEEECCCCCCCCEEEEECCCCCCEEEEEHHHHCCCCCCCCCHHHHHHHHC
MGDILALVEEAQRGVDVQAAQKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
QFQQAAAGADMGHAEKQIRRMEGIINSMTPAERAKPDLIKATRKRRIAAGAGVPVQEVNR
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
MLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGLR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVALPVVREFIAKVKEKAL
CCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEEVISSLSPGQALVGVVQKELTAVIGGDYEGKAVELNLAVTPPAIILMAGLQGAGKTTT
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHHCCCCCCCCHH
VGKLAKLLREKQKKKVLTVSCDVYRPAAIAQLKTVSEQVGADFFPSTPEQKPVEIARAAL
HHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
DWARRHYHDVLIVDTAGRLGIDEAMMKEIAELHAAINPAETLFVVDAMLGQDAVNTAKAF
HHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHH
NDALPLTGVVLTKLDGDSRGGAALSVRSITGKPIKFVGVAEKLDGLEVFHPDRMANRILG
HCCCCHHHEEEEEECCCCCCCCEEEEECCCCCCEEEEEHHHHCCCCCCCCCHHHHHHHHC
MGDILALVEEAQRGVDVQAAQKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
QFQQAAAGADMGHAEKQIRRMEGIINSMTPAERAKPDLIKATRKRRIAAGAGVPVQEVNR
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
MLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGLR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]