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The map label for this gene is obg [H]

Identifier: 238026155

GI number: 238026155

Start: 512553

End: 513674

Strand: Direct

Name: obg [H]

Synonym: bglu_1g04850

Alternate gene names: 238026155

Gene position: 512553-513674 (Clockwise)

Preceding gene: 238026154

Following gene: 238026156

Centisome position: 13.12

GC content: 68.45

Gene sequence:

>1122_bases
ATGAAGTTCATTGACGAAGCGCGAATCGAGGTCATCGCCGGCGACGGAGGCGATGGCAGCGCGTCGATGCGCCGCGAGAA
GTTCGTTCCGTTCGGCGGGCCGGACGGCGGCGACGGCGGCCGGGGCGGCAGCGTCTACGCGGTCGCGGATCGCAACATCA
ACACGCTGATCGATTATCGATACGCGAAGAAGCACCTGGCGCGCAACGGCGAGAACGGCCGCGGCTCCGACTGCTATGGC
AAGGGCGGCGACGACATCACGCTGCGCATGCCGGTCGGCACCGTCATCACCGACCTGGACACGGGCGAACTGATCGCCGA
CCTGACCGAGCACGAGCAGAAGGTGCTCGTCGCGCAGGGCGGCGCGGGCGGCCTCGGCAACCTGCACTTCAAGTCGAGCA
CGAACCGCGCGCCGCGCCAGAAGACCGAAGGCAAGCCCGGCGAGCGCCGCATGCTGCGGCTCGAGCTCAAGGTGCTGGCC
GATGTCGGCCTGCTCGGCATGCCGAATGCGGGCAAGTCCACCTTCATCTCGTCGGTGTCGAACGCGAAGCCGAAGATCGC
CGACTACCCGTTCACGACGCTCGCGCCGAATCTCGGCGTGGTGCGCGTGGGGCCGAGCAAGAGCTTCGTGATCGCCGACA
TTCCGGGCCTGATCGAAGGCGCCGCCGAGGGCGCGGGCCTCGGCCACCAGTTCCTGCGCCACCTCCAGCGCACCGGCGTG
CTGCTGCATCTGGTCGATCTGGCGCCGTTCGACGAAGGTGTCGATCCCGTGGCGGAAGCGACGGCGATCGTCGGCGAACT
GCGCAAGTACGATGAAGCGCTCTACCAGAAGCCGCGCTGGCTCGTGCTGAACAAGCTCGACATGGTGCCGGAGGACGAAC
GCGCCGCGCGTGTTGCCGATTTCGTCAGCCGCTTCGGCTGGGACGGCCCGGTGTTCGAGATTTCCGCACTGACGGGGCAG
GGCTGCGAGAACCTCGTCTATGCCGTCTATGACTACCTCGTCGAGCATTCGGACGCGCATCGCGCCTCCGAGGCCGAGGA
CCTGGCCGCCGACGTGCGCTTTCGCGACGCCCCCGCGCCGGGTGGCGGCGAGGCGCCGCCGGAGCCCGAAGCCGGCGACT
GA

Upstream 100 bases:

>100_bases
TTCCGATCCGGGCCGGCGCGGCAACCTGGCCGCACGGCCGATTGGTCAAGCGCGGCGCCACGCGGCACAATATTGGATCA
ATTCAGGCGGAGCTTGACGG

Downstream 100 bases:

>100_bases
ACCGGCCGCCGGGCCATTAACCGGGCTTGGCCGACGCGGCATCCGAACCGGCGCGTGCCTCGGCCGATGGACGGCGAGCC
CGCGCCGGCGCCGGTCCGAC

Product: GTPase CgtA

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAVADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDITLRMPVGTVITDLDTGELIADLTEHEQKVLVAQGGAGGLGNLHFKSSTNRAPRQKTEGKPGERRMLRLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
LLHLVDLAPFDEGVDPVAEATAIVGELRKYDEALYQKPRWLVLNKLDMVPEDERAARVADFVSRFGWDGPVFEISALTGQ
GCENLVYAVYDYLVEHSDAHRASEAEDLAADVRFRDAPAPGGGEAPPEPEAGD

Sequences:

>Translated_373_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAVADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDITLRMPVGTVITDLDTGELIADLTEHEQKVLVAQGGAGGLGNLHFKSSTNRAPRQKTEGKPGERRMLRLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
LLHLVDLAPFDEGVDPVAEATAIVGELRKYDEALYQKPRWLVLNKLDMVPEDERAARVADFVSRFGWDGPVFEISALTGQ
GCENLVYAVYDYLVEHSDAHRASEAEDLAADVRFRDAPAPGGGEAPPEPEAGD
>Mature_373_residues
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAVADRNINTLIDYRYAKKHLARNGENGRGSDCYG
KGGDDITLRMPVGTVITDLDTGELIADLTEHEQKVLVAQGGAGGLGNLHFKSSTNRAPRQKTEGKPGERRMLRLELKVLA
DVGLLGMPNAGKSTFISSVSNAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
LLHLVDLAPFDEGVDPVAEATAIVGELRKYDEALYQKPRWLVLNKLDMVPEDERAARVADFVSRFGWDGPVFEISALTGQ
GCENLVYAVYDYLVEHSDAHRASEAEDLAADVRFRDAPAPGGGEAPPEPEAGD

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=336, Percent_Identity=38.9880952380952, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI111955139, Length=359, Percent_Identity=35.933147632312, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI111955063, Length=193, Percent_Identity=37.8238341968912, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI58761500, Length=136, Percent_Identity=31.6176470588235, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789574, Length=336, Percent_Identity=58.3333333333333, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=36, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508313, Length=327, Percent_Identity=38.2262996941896, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=313, Percent_Identity=30.9904153354633, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=34.375, Blast_Score=74, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321962, Length=197, Percent_Identity=37.5634517766497, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6321773, Length=155, Percent_Identity=29.0322580645161, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24585318, Length=312, Percent_Identity=40.7051282051282, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI20129375, Length=341, Percent_Identity=36.3636363636364, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24640873, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24640877, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24640875, Length=134, Percent_Identity=34.3283582089552, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 39850; Mature: 39850

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAVADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
YAKKHLARNGENGRGSDCYGKGGDDITLRMPVGTVITDLDTGELIADLTEHEQKVLVAQG
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHCCCEEEEEEC
GAGGLGNLHFKSSTNRAPRQKTEGKPGERRMLRLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHLVDLAPFDEGVDPVAEATAIVGELRKYDEALYQKPRWLVLNKLDMVPEDERAARVAD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHH
FVSRFGWDGPVFEISALTGQGCENLVYAVYDYLVEHSDAHRASEAEDLAADVRFRDAPAP
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEECCCCC
GGGEAPPEPEAGD
CCCCCCCCCCCCC
>Mature Secondary Structure
MKFIDEARIEVIAGDGGDGSASMRREKFVPFGGPDGGDGGRGGSVYAVADRNINTLIDYR
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHH
YAKKHLARNGENGRGSDCYGKGGDDITLRMPVGTVITDLDTGELIADLTEHEQKVLVAQG
HHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCHHHHHHHHHCCCEEEEEEC
GAGGLGNLHFKSSTNRAPRQKTEGKPGERRMLRLELKVLADVGLLGMPNAGKSTFISSVS
CCCCCCCEEECCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
NAKPKIADYPFTTLAPNLGVVRVGPSKSFVIADIPGLIEGAAEGAGLGHQFLRHLQRTGV
CCCCCCCCCCHHHHCCCCCEEEECCCCCEEEEECCHHHHHHHCCCCHHHHHHHHHHHCCE
LLHLVDLAPFDEGVDPVAEATAIVGELRKYDEALYQKPRWLVLNKLDMVPEDERAARVAD
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHH
FVSRFGWDGPVFEISALTGQGCENLVYAVYDYLVEHSDAHRASEAEDLAADVRFRDAPAP
HHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEECCCCC
GGGEAPPEPEAGD
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA