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The map label for this gene is murC [H]

Identifier: 238026133

GI number: 238026133

Start: 489467

End: 490867

Strand: Direct

Name: murC [H]

Synonym: bglu_1g04630

Alternate gene names: 238026133

Gene position: 489467-490867 (Clockwise)

Preceding gene: 238026132

Following gene: 238026134

Centisome position: 12.53

GC content: 70.09

Gene sequence:

>1401_bases
ATGAAACACATCGTCAAACACGTCCATTTCGTCGGCATCGGCGGCGCCGGCATGAGCGGCATCGCCGAGGTGCTGGTGAA
CCTCGGCTACGAGGTCAGCGGCTCGGACCTGTCGCGCAATGCCGTGACGGAACGGCTCACCGCACTCGGCGCGCGTGTCG
CGATCGGCCACGACGCGGCCAATATCGAGGGCGCGAACGCGGTCGTCACGTCCACGGCGGTGCGCTCGGACAATCCGGAA
GTGCTCGCGGCGCGGCGCCTGGGCGTGCCGATCGTGCCGCGCGCGGTGATGCTGGCCGAGCTGATGCGCCTGAAGCAGGG
CATCGCAATCGCCGGCACCCACGGCAAGACCACCACCACCAGCCTGGTGGCGAGCGTGCTCGCGGCGGGCGGCCTGGACC
CGACCTTCGTGATCGGCGGGCGCCTGATCAGCGCCGGCGCGAACGCGCGGCTCGGCTCGGGCGACTTCATCGTCGCCGAG
GCCGACGAGTCGGACGCCTCGTTTTTGAACCTGTATCCCGTCATCGAGGTGATCACCAACATCGACGAGGATCACATGGA
CACCTACGGGCACGACTTCGCGCGGCTCAAGCAGGCGTTCATCGAATTCACCCAGAAGCTGCCGTTCTACGGCAGCGTGG
TGGTCTGCGTCGACGATCCGAACGTGCGTCAGATCCTGCCGTTCATCTCGAAGCCGGTGGTGCGCTACGGTCTCGCGCCC
GATGCCGAGGTCCGCGCCGAGCAGGTGGCGGCGCGTGACGGCCGCATGCATTTCACTGCGATCCGCGAGGGCCGCGCGCC
GCTGGCGGTGGTGCTGAACCTGCCGGGCCTGCACAACGTGCAGAACGCGCTCGCGGCGATCGCCATCGCGACCGACCTCG
GCGTGGCCGACGCGGCGATCCAGCAGGCGCTTGCCGATTTCAACGGGGTCGGCCGGCGCTTTCAGCGCTACGGCGAGATC
GCGACGGCCGACGGCGCGGGCAGCTACACGCTGGTGGACGACTACGGCCACCATCCGGTCGAGATGGCCGCCACGATCGC
CGCCGCGCGCGGCGCGTTTCCGGGCCGCCGGCTGGTGCTGGCGTTCCAGCCTCACCGTTACACGCGCACGCGCGACTGCT
TCGAGGAATTCGTCAACGTGCTCTCGACCGTCGACGAGCTGGTGCTGACCGAGGTCTACGCCGCCGGCGAGGCGCCGATC
CCGACCGCGAGCGGCGAGGCGCTCGCTCGCGCGCTGCGTGCGAGCGGTCGCGTCGATCCCGCGTTCGTGGCGACGGTCGA
CGAGGTGCCGGCGGCGCTCGCGCAGCGCGTGCGCGCGGGCGACGTGGTGATCACGATGGGCGCGGGGTCGATCGGCGGCG
TGCCGGGCCGGATCGCGCAGCAACAGCAACGGAAGGAATGA

Upstream 100 bases:

>100_bases
AGATGGCCGAACGTTCGCGCTCGCTCGCGAAGCCCGACGCCACCGACGTGGTCGCGCGCGTGTGCGCGCAGGTGGCCGGC
GCGAACCTGGAATCGAAGTC

Downstream 100 bases:

>100_bases
CATGAGCGGGATCGATCCGAAACGTTTCGGCAAGGTGGCGGTACTGTTCGGCGGCGTGTCCGCCGAGCGCGAGGTGTCGC
TGAATTCGGGCCGGCTGGTG

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MKHIVKHVHFVGIGGAGMSGIAEVLVNLGYEVSGSDLSRNAVTERLTALGARVAIGHDAANIEGANAVVTSTAVRSDNPE
VLAARRLGVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGSGDFIVAE
ADESDASFLNLYPVIEVITNIDEDHMDTYGHDFARLKQAFIEFTQKLPFYGSVVVCVDDPNVRQILPFISKPVVRYGLAP
DAEVRAEQVAARDGRMHFTAIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVADAAIQQALADFNGVGRRFQRYGEI
ATADGAGSYTLVDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFEEFVNVLSTVDELVLTEVYAAGEAPI
PTASGEALARALRASGRVDPAFVATVDEVPAALAQRVRAGDVVITMGAGSIGGVPGRIAQQQQRKE

Sequences:

>Translated_466_residues
MKHIVKHVHFVGIGGAGMSGIAEVLVNLGYEVSGSDLSRNAVTERLTALGARVAIGHDAANIEGANAVVTSTAVRSDNPE
VLAARRLGVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGSGDFIVAE
ADESDASFLNLYPVIEVITNIDEDHMDTYGHDFARLKQAFIEFTQKLPFYGSVVVCVDDPNVRQILPFISKPVVRYGLAP
DAEVRAEQVAARDGRMHFTAIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVADAAIQQALADFNGVGRRFQRYGEI
ATADGAGSYTLVDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFEEFVNVLSTVDELVLTEVYAAGEAPI
PTASGEALARALRASGRVDPAFVATVDEVPAALAQRVRAGDVVITMGAGSIGGVPGRIAQQQQRKE
>Mature_466_residues
MKHIVKHVHFVGIGGAGMSGIAEVLVNLGYEVSGSDLSRNAVTERLTALGARVAIGHDAANIEGANAVVTSTAVRSDNPE
VLAARRLGVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAAGGLDPTFVIGGRLISAGANARLGSGDFIVAE
ADESDASFLNLYPVIEVITNIDEDHMDTYGHDFARLKQAFIEFTQKLPFYGSVVVCVDDPNVRQILPFISKPVVRYGLAP
DAEVRAEQVAARDGRMHFTAIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVADAAIQQALADFNGVGRRFQRYGEI
ATADGAGSYTLVDDYGHHPVEMAATIAAARGAFPGRRLVLAFQPHRYTRTRDCFEEFVNVLSTVDELVLTEVYAAGEAPI
PTASGEALARALRASGRVDPAFVATVDEVPAALAQRVRAGDVVITMGAGSIGGVPGRIAQQQQRKE

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=459, Percent_Identity=52.0697167755991, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1790680, Length=469, Percent_Identity=28.997867803838, Blast_Score=169, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49108; Mature: 49108

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIVKHVHFVGIGGAGMSGIAEVLVNLGYEVSGSDLSRNAVTERLTALGARVAIGHDAA
CCHHHHHEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCC
NIEGANAVVTSTAVRSDNPEVLAARRLGVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTT
CCCCCCEEEEEHHHCCCCCCEEEHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLISAGANARLGSGDFIVAEADESDASFLNLYPVIEVITN
HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDEDHMDTYGHDFARLKQAFIEFTQKLPFYGSVVVCVDDPNVRQILPFISKPVVRYGLAP
CCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCC
DAEVRAEQVAARDGRMHFTAIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVADAAI
CHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHH
QQALADFNGVGRRFQRYGEIATADGAGSYTLVDDYGHHPVEMAATIAAARGAFPGRRLVL
HHHHHHHHHHHHHHHHHCCEEECCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEE
AFQPHRYTRTRDCFEEFVNVLSTVDELVLTEVYAAGEAPIPTASGEALARALRASGRVDP
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
AFVATVDEVPAALAQRVRAGDVVITMGAGSIGGVPGRIAQQQQRKE
HHEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKHIVKHVHFVGIGGAGMSGIAEVLVNLGYEVSGSDLSRNAVTERLTALGARVAIGHDAA
CCHHHHHEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCC
NIEGANAVVTSTAVRSDNPEVLAARRLGVPIVPRAVMLAELMRLKQGIAIAGTHGKTTTT
CCCCCCEEEEEHHHCCCCCCEEEHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHH
SLVASVLAAGGLDPTFVIGGRLISAGANARLGSGDFIVAEADESDASFLNLYPVIEVITN
HHHHHHHHHCCCCCEEEECCEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHC
IDEDHMDTYGHDFARLKQAFIEFTQKLPFYGSVVVCVDDPNVRQILPFISKPVVRYGLAP
CCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCC
DAEVRAEQVAARDGRMHFTAIREGRAPLAVVLNLPGLHNVQNALAAIAIATDLGVADAAI
CHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHH
QQALADFNGVGRRFQRYGEIATADGAGSYTLVDDYGHHPVEMAATIAAARGAFPGRRLVL
HHHHHHHHHHHHHHHHHCCEEECCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEE
AFQPHRYTRTRDCFEEFVNVLSTVDELVLTEVYAAGEAPIPTASGEALARALRASGRVDP
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCC
AFVATVDEVPAALAQRVRAGDVVITMGAGSIGGVPGRIAQQQQRKE
HHEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA