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The map label for this gene is yhcK [H]

Identifier: 238026056

GI number: 238026056

Start: 395986

End: 397173

Strand: Direct

Name: yhcK [H]

Synonym: bglu_1g03840

Alternate gene names: 238026056

Gene position: 395986-397173 (Clockwise)

Preceding gene: 238026052

Following gene: 238026060

Centisome position: 10.14

GC content: 69.19

Gene sequence:

>1188_bases
ATGTCCGCCATCACCGTTGCTCTGGCTACTACCGCGCTGTTCGGACTCGTGATGCTCGTGCTGCTCGGCTCGCTGGTGCG
CACCGGCGCGGCCGGCGTGCGCGAGTGGTTCGCGGCAAACCTGATGCTGTCGGTGTCGCTCGCGCTGCTGCTCGCGCGCG
GCAGGATGCCCGACATCTTCACGGTGGTGCTCGGCAACGGCATGCTGGTGCTCTCGGGCGTCACGCTCTATGCCGGCTAC
GCGCGCTTTCTCGGCTTGCCGCCGCGCTGGCCCTGGCTCGCGCTGTTCACGGGCCTGACGCTGCCGGCCCTGGTTTACTG
GCACTACATGGCCGACAGCATCCCGACGCGGGTGGGCATCACCACGTCCTACACGGCCATCGTCTGCATCGCGATCGCGG
TCATCGTGATCCGGCGTTATCGCACGGGCCAGTCGCGCTATCCCTATGTCGCCACCGCAGGCCTGGCCGCGCTGTTCGCG
ATCAGCCAGATCCTGCGCGGCGCCTACTTCATGATGCTGCCGGGGCCGGTGGGCGCGCAGGCGTATCTGGGCACGTTCAA
CATCAGCCTGCTCTGCGTGGGCGCGGCGATCATGCCGGTGATGTCGATGTGCGCGATCATGATGGTTCACGATTCGATGC
AGCTGGCCGCGCGCCGCGTGATCGACCACGACTTCCTCACGCGTGCGCTGTCGCGGCAGCGTTTCGAGGTGGTGGCGCGC
GCCCGCGTGCGCGATGCGGAACGCGATGGCACGCCGCTGTCGCTGCTGCTGATCGACCTCGACCACTTCAAGTCGATCAA
CGACACCTACGGCCACGCGGGCGGCGACGCGGTGCTGCGCGAGTTCGCCGAGCTGATGCTGCAGAAGCTGCGCGGCGGCG
ATGCGCTGGGCCGCCTCGGCGGTGAGGAGTTCGCGGTCCTGCTGCCGCGCACGACGCTCTCGGACGCGCTGCGCATCGCC
GACCGCCTGCGCGACGAGGTCAGCCGGCACACGGTGGAAACGGCGGCGGGGCTCTGCTCGTACAGCACCAGCGGCGGGCT
CGCGAGCCGCATGCCCGGCGAAACCTTCGAGCAGATGTCGGCGCGCGCCGACCGCGCGCTCTACGACGCAAAGGTCTCGG
GCCGCAACCGCGTCTGCGCGCACGCGGGCATGTCGCAATCGGCGATCGCGCAGTTCGACTCGGTCTGA

Upstream 100 bases:

>100_bases
ATTTCACATTCGATTTTTCCCGAAGCTGTTAAATTCCGGTCTCCGTCGATCCGTCCGAGCGCCGCTTGCCCCCGCGCGTT
GCTGAGTATCCGCCCCTGCC

Downstream 100 bases:

>100_bases
AACGCCGGCGGCGCTACCGGGCAGCACGCACGAGGCGCTGCCGGCGGGCCGGCGAAGAGGGGGAAGGCAGGCGTCGTGGC
GCCGCCAGGCCGCTGCTCGG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSAITVALATTALFGLVMLVLLGSLVRTGAAGVREWFAANLMLSVSLALLLARGRMPDIFTVVLGNGMLVLSGVTLYAGY
ARFLGLPPRWPWLALFTGLTLPALVYWHYMADSIPTRVGITTSYTAIVCIAIAVIVIRRYRTGQSRYPYVATAGLAALFA
ISQILRGAYFMMLPGPVGAQAYLGTFNISLLCVGAAIMPVMSMCAIMMVHDSMQLAARRVIDHDFLTRALSRQRFEVVAR
ARVRDAERDGTPLSLLLIDLDHFKSINDTYGHAGGDAVLREFAELMLQKLRGGDALGRLGGEEFAVLLPRTTLSDALRIA
DRLRDEVSRHTVETAAGLCSYSTSGGLASRMPGETFEQMSARADRALYDAKVSGRNRVCAHAGMSQSAIAQFDSV

Sequences:

>Translated_395_residues
MSAITVALATTALFGLVMLVLLGSLVRTGAAGVREWFAANLMLSVSLALLLARGRMPDIFTVVLGNGMLVLSGVTLYAGY
ARFLGLPPRWPWLALFTGLTLPALVYWHYMADSIPTRVGITTSYTAIVCIAIAVIVIRRYRTGQSRYPYVATAGLAALFA
ISQILRGAYFMMLPGPVGAQAYLGTFNISLLCVGAAIMPVMSMCAIMMVHDSMQLAARRVIDHDFLTRALSRQRFEVVAR
ARVRDAERDGTPLSLLLIDLDHFKSINDTYGHAGGDAVLREFAELMLQKLRGGDALGRLGGEEFAVLLPRTTLSDALRIA
DRLRDEVSRHTVETAAGLCSYSTSGGLASRMPGETFEQMSARADRALYDAKVSGRNRVCAHAGMSQSAIAQFDSV
>Mature_394_residues
SAITVALATTALFGLVMLVLLGSLVRTGAAGVREWFAANLMLSVSLALLLARGRMPDIFTVVLGNGMLVLSGVTLYAGYA
RFLGLPPRWPWLALFTGLTLPALVYWHYMADSIPTRVGITTSYTAIVCIAIAVIVIRRYRTGQSRYPYVATAGLAALFAI
SQILRGAYFMMLPGPVGAQAYLGTFNISLLCVGAAIMPVMSMCAIMMVHDSMQLAARRVIDHDFLTRALSRQRFEVVARA
RVRDAERDGTPLSLLLIDLDHFKSINDTYGHAGGDAVLREFAELMLQKLRGGDALGRLGGEEFAVLLPRTTLSDALRIAD
RLRDEVSRHTVETAAGLCSYSTSGGLASRMPGETFEQMSARADRALYDAKVSGRNRVCAHAGMSQSAIAQFDSV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=174, Percent_Identity=36.2068965517241, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87082007, Length=162, Percent_Identity=40.7407407407407, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI87081881, Length=205, Percent_Identity=36.0975609756098, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1787262, Length=182, Percent_Identity=32.4175824175824, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787802, Length=189, Percent_Identity=35.4497354497354, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1788381, Length=178, Percent_Identity=35.3932584269663, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1787816, Length=132, Percent_Identity=36.3636363636364, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786584, Length=155, Percent_Identity=34.1935483870968, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788085, Length=188, Percent_Identity=28.7234042553192, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787056, Length=158, Percent_Identity=33.5443037974684, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787541, Length=134, Percent_Identity=33.5820895522388, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081974, Length=138, Percent_Identity=26.8115942028986, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 42721; Mature: 42589

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAITVALATTALFGLVMLVLLGSLVRTGAAGVREWFAANLMLSVSLALLLARGRMPDIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
TVVLGNGMLVLSGVTLYAGYARFLGLPPRWPWLALFTGLTLPALVYWHYMADSIPTRVGI
HHHHCCCEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TTSYTAIVCIAIAVIVIRRYRTGQSRYPYVATAGLAALFAISQILRGAYFMMLPGPVGAQ
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCH
AYLGTFNISLLCVGAAIMPVMSMCAIMMVHDSMQLAARRVIDHDFLTRALSRQRFEVVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARVRDAERDGTPLSLLLIDLDHFKSINDTYGHAGGDAVLREFAELMLQKLRGGDALGRLG
HHHHHCCCCCCCEEEEEEEHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCC
GEEFAVLLPRTTLSDALRIADRLRDEVSRHTVETAAGLCSYSTSGGLASRMPGETFEQMS
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
ARADRALYDAKVSGRNRVCAHAGMSQSAIAQFDSV
HHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHCCC
>Mature Secondary Structure 
SAITVALATTALFGLVMLVLLGSLVRTGAAGVREWFAANLMLSVSLALLLARGRMPDIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
TVVLGNGMLVLSGVTLYAGYARFLGLPPRWPWLALFTGLTLPALVYWHYMADSIPTRVGI
HHHHCCCEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TTSYTAIVCIAIAVIVIRRYRTGQSRYPYVATAGLAALFAISQILRGAYFMMLPGPVGAQ
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCH
AYLGTFNISLLCVGAAIMPVMSMCAIMMVHDSMQLAARRVIDHDFLTRALSRQRFEVVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARVRDAERDGTPLSLLLIDLDHFKSINDTYGHAGGDAVLREFAELMLQKLRGGDALGRLG
HHHHHCCCCCCCEEEEEEEHHHHCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCC
GEEFAVLLPRTTLSDALRIADRLRDEVSRHTVETAAGLCSYSTSGGLASRMPGETFEQMS
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
ARADRALYDAKVSGRNRVCAHAGMSQSAIAQFDSV
HHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]