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The map label for this gene is sdaA [H]

Identifier: 238025775

GI number: 238025775

Start: 109537

End: 110925

Strand: Reverse

Name: sdaA [H]

Synonym: bglu_1g00990

Alternate gene names: 238025775

Gene position: 110925-109537 (Counterclockwise)

Preceding gene: 238025776

Following gene: 238025774

Centisome position: 2.84

GC content: 70.41

Gene sequence:

>1389_bases
ATGGCAGTCAGCGTGTTCGATCTTTTCAAAATCGGGATTGGCCCGTCCAGCTCGCACACGGTGGGACCGATGCGCGCCGC
GCTGATGTTCGTCCAGGGCCTCGAGCGCGACGAGCTGCTCGAGCGCACCGCCACCGTGAAGGTCGACCTGTACGGCTCGC
TCGGCGCGACCGGCAAGGGCCACGGCACCGACCGCGGCGTGATGCTGGGACTGATGGGCGACGCGCCCGATACGGTCGAC
CCCGACACCATCGACGCGCGGCTCGCCGAGGTGCGCGACACGCGCAAGCTCGCGCTGCTGGGCCGCCATCCGGTGCCGTT
CGTGCTCAAGGAGCAGATCGGCTTCTACCGGCAGGCGCTGCCCGAGCATCCGAACGCGATGACGCTGCGCGCGCGCGACG
CGGCCGGCGCGCCGCTGCGCGAGACCACCTACCTGTCGGTGGGCGGCGGCTTCGTGGTGACGGCCGGCGCGCCGAACACC
AAGGTGCTGAGCGCGGCCGAGCAGATGCCCTACCCGTTTCGCACCAGCGCCGAGCTGCTCGCGCTGACCGCCAGCACCGG
CAAGTCGATCGCGCAGCTGATGTGGGACAACGAGCGCGCCTGGCACGACGAGGCCGCCACGCGCGCCGGCCTGCTGAAGA
TCTGGGAGGTGATGCAGTCGTGCGTGTCGCGCGGCTGCGGGATCGGCAACCCCGACGCGCACGGCACGCTGCCCGGCCCG
TTCCAGGTCAAGCGCCGCGCGCCGCAGCTGTATCGCACGCTGACGGGCAATCCCGAGCTGGCGCTGCGCGACCCGCTCTC
GATGATCGACTGGATCAACCTCTACGCGATCGCCGTGAACGAGGAAAACGCCGCCGGCGGCCGGGTGGTGACGGCGCCCA
CCAACGGCGCGGCCGGCATCATCCCCGCCGTGCTGCACTACTACATGCGCTTCACGCCCGGCGCGAACGAGCAGGGCGTG
ATCGACTTCCTGATGACGGCCGCCGCGATCGGCATCCTCTACAAGCTCAACGCGTCGATCTCGGGCGCCGAGGTGGGCTG
CCAGGGCGAGGTGGGGGTGGCCTGCTCGATGGCCGCCGGCGCGCTGGCCGCCGTGCTGGGCGGCACGCCGCGCCAGGTCG
AGAACGCCGCCGAGATCGGCATGGAACACAACCTCGGGCTGACTTGCGACCCGGTGGGCGGGATGGTGCAGATCCCCTGC
ATCGAGCGCAACGCGATGGCCTCGGTGAAGGCCGTCAACGCCGCGCGCATGGCGCTGCGCGGCGACGGCAGCCACTACGT
GTCGCTCGACTCGGTGATCAAGACCATGCGCGAGACGGGCGCCGACATGAAGACGAAGTACAAGGAAACCTCGCGCGGCG
GGCTCGCGGTGAACATCGTCGAGTGCTGA

Upstream 100 bases:

>100_bases
CGTCGCGCAGCTGCTCGCGCCGCAGCCGCCCGCCTGGGTGGCCGCGTGCCTGCCGCTGCCGGCCCGTTAACCCCGCATCC
CCCGAATCACAGGAAACCCC

Downstream 100 bases:

>100_bases
GCGCCGCCGGCGCGCCGCGCGCGCCGGTGTGAGGCGCTGCGGCGTCCCGCGGCCCGGGCCGCGCCTGCCTGCGGCCCGCC
GCCTTCCGCGCGGCCTGCCT

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MAVSVFDLFKIGIGPSSSHTVGPMRAALMFVQGLERDELLERTATVKVDLYGSLGATGKGHGTDRGVMLGLMGDAPDTVD
PDTIDARLAEVRDTRKLALLGRHPVPFVLKEQIGFYRQALPEHPNAMTLRARDAAGAPLRETTYLSVGGGFVVTAGAPNT
KVLSAAEQMPYPFRTSAELLALTASTGKSIAQLMWDNERAWHDEAATRAGLLKIWEVMQSCVSRGCGIGNPDAHGTLPGP
FQVKRRAPQLYRTLTGNPELALRDPLSMIDWINLYAIAVNEENAAGGRVVTAPTNGAAGIIPAVLHYYMRFTPGANEQGV
IDFLMTAAAIGILYKLNASISGAEVGCQGEVGVACSMAAGALAAVLGGTPRQVENAAEIGMEHNLGLTCDPVGGMVQIPC
IERNAMASVKAVNAARMALRGDGSHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNIVEC

Sequences:

>Translated_462_residues
MAVSVFDLFKIGIGPSSSHTVGPMRAALMFVQGLERDELLERTATVKVDLYGSLGATGKGHGTDRGVMLGLMGDAPDTVD
PDTIDARLAEVRDTRKLALLGRHPVPFVLKEQIGFYRQALPEHPNAMTLRARDAAGAPLRETTYLSVGGGFVVTAGAPNT
KVLSAAEQMPYPFRTSAELLALTASTGKSIAQLMWDNERAWHDEAATRAGLLKIWEVMQSCVSRGCGIGNPDAHGTLPGP
FQVKRRAPQLYRTLTGNPELALRDPLSMIDWINLYAIAVNEENAAGGRVVTAPTNGAAGIIPAVLHYYMRFTPGANEQGV
IDFLMTAAAIGILYKLNASISGAEVGCQGEVGVACSMAAGALAAVLGGTPRQVENAAEIGMEHNLGLTCDPVGGMVQIPC
IERNAMASVKAVNAARMALRGDGSHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNIVEC
>Mature_461_residues
AVSVFDLFKIGIGPSSSHTVGPMRAALMFVQGLERDELLERTATVKVDLYGSLGATGKGHGTDRGVMLGLMGDAPDTVDP
DTIDARLAEVRDTRKLALLGRHPVPFVLKEQIGFYRQALPEHPNAMTLRARDAAGAPLRETTYLSVGGGFVVTAGAPNTK
VLSAAEQMPYPFRTSAELLALTASTGKSIAQLMWDNERAWHDEAATRAGLLKIWEVMQSCVSRGCGIGNPDAHGTLPGPF
QVKRRAPQLYRTLTGNPELALRDPLSMIDWINLYAIAVNEENAAGGRVVTAPTNGAAGIIPAVLHYYMRFTPGANEQGVI
DFLMTAAAIGILYKLNASISGAEVGCQGEVGVACSMAAGALAAVLGGTPRQVENAAEIGMEHNLGLTCDPVGGMVQIPCI
ERNAMASVKAVNAARMALRGDGSHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNIVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=461, Percent_Identity=53.1453362255965, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI48994925, Length=459, Percent_Identity=53.5947712418301, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1789161, Length=461, Percent_Identity=53.1453362255965, Blast_Score=457, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48904; Mature: 48773

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSVFDLFKIGIGPSSSHTVGPMRAALMFVQGLERDELLERTATVKVDLYGSLGATGKG
CEEEHEEHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHEEEEEEEEECCCCCCCC
HGTDRGVMLGLMGDAPDTVDPDTIDARLAEVRDTRKLALLGRHPVPFVLKEQIGFYRQAL
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHC
PEHPNAMTLRARDAAGAPLRETTYLSVGGGFVVTAGAPNTKVLSAAEQMPYPFRTSAELL
CCCCCEEEEEECCCCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHCCCCCCCCCEEE
ALTASTGKSIAQLMWDNERAWHDEAATRAGLLKIWEVMQSCVSRGCGIGNPDAHGTLPGP
EEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
FQVKRRAPQLYRTLTGNPELALRDPLSMIDWINLYAIAVNEENAAGGRVVTAPTNGAAGI
HHHHHHCHHHHHHHCCCCCEEECCCHHHHHHEEEEEEEEECCCCCCCEEEECCCCCCCHH
IPAVLHYYMRFTPGANEQGVIDFLMTAAAIGILYKLNASISGAEVGCQGEVGVACSMAAG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHH
ALAAVLGGTPRQVENAAEIGMEHNLGLTCDPVGGMVQIPCIERNAMASVKAVNAARMALR
HHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEEEEEECCCHHHHHHHHHHHHHEEE
GDGSHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNIVEC
CCCCCEEEHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure 
AVSVFDLFKIGIGPSSSHTVGPMRAALMFVQGLERDELLERTATVKVDLYGSLGATGKG
EEEHEEHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHEEEEEEEEECCCCCCCC
HGTDRGVMLGLMGDAPDTVDPDTIDARLAEVRDTRKLALLGRHPVPFVLKEQIGFYRQAL
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHC
PEHPNAMTLRARDAAGAPLRETTYLSVGGGFVVTAGAPNTKVLSAAEQMPYPFRTSAELL
CCCCCEEEEEECCCCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHCCCCCCCCCEEE
ALTASTGKSIAQLMWDNERAWHDEAATRAGLLKIWEVMQSCVSRGCGIGNPDAHGTLPGP
EEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
FQVKRRAPQLYRTLTGNPELALRDPLSMIDWINLYAIAVNEENAAGGRVVTAPTNGAAGI
HHHHHHCHHHHHHHCCCCCEEECCCHHHHHHEEEEEEEEECCCCCCCEEEECCCCCCCHH
IPAVLHYYMRFTPGANEQGVIDFLMTAAAIGILYKLNASISGAEVGCQGEVGVACSMAAG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHH
ALAAVLGGTPRQVENAAEIGMEHNLGLTCDPVGGMVQIPCIERNAMASVKAVNAARMALR
HHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEEEEEECCCHHHHHHHHHHHHHEEE
GDGSHYVSLDSVIKTMRETGADMKTKYKETSRGGLAVNIVEC
CCCCCEEEHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]