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The map label for this gene is xapR [H]

Identifier: 238025734

GI number: 238025734

Start: 57131

End: 58030

Strand: Reverse

Name: xapR [H]

Synonym: bglu_1g00560

Alternate gene names: 238025734

Gene position: 58030-57131 (Counterclockwise)

Preceding gene: 238025757

Following gene: 238025733

Centisome position: 1.49

GC content: 73.22

Gene sequence:

>900_bases
ATGGATCTGATCCTGCTTCGCGCCTTCGCCGCGGTGGCCCGTGAAGGCAACCTGACGCGCGCGGCCGCGCAGCTCTGCCT
CACGCAGCCCGCCGTCAGCCTGCAGATCAAGCATCTGCAGCAGGCGCTCGGCGTGGCGCTGTTCGCGCGCACCTCGCGCG
GCCTGGGACTCACGCGCGACGGACAGGCGCTGCTGCCGCATGCCGAACGCGCGCTGGCGGCGGCCGGCGAGGTGCTGCGC
GCGGCCAGCGCGCTGCGCCAGGAGGTGCGTGGCCGGCTGCGGATCGGCACGGTGCTCGATCCCGAATTCCTGCGGCTCGG
CGGTTTCCTGCGCCAGCTCGTCGAAACCCACCCGCGGCTCGAGACCGAGCTGCGGCACGGCATGTCCGGCTGGGTGCGCG
ACGCGGTGCGCACGCGCGAACTCGATGTCGGCTATTCGATCGGCCGCCCCGACGACGACGATCCGCACCACGGTGCGCTG
TTTCACACCCGCACGCTCACCCGCTACCAGTATCGCGTGCTCGCGCCGGCCGGCTGGAAGGAGCGCGTGCAGCGCGCCCG
CGACTGGCGCGCGCTGGCAGCGCTGCCGTGGATCTGGACCCCGCCGTCCTCGGCGCATCACCGGCTGCTGTCGCGCCGCT
TCGCCGAGGCCGGCGTGCAGCCGATGAAGGTGGCCGAGGTCGATCAGGAGCCGTCGATGCTCGATCTCGTGAAGTCCGGC
GTGGGGCTCACGCTCGCGCGCGATTCGATCGCGCTGCGCGAGGCGCACGCGCATGCGCTCGTGATCGTCGAGGCGGTGAC
GGTGCCCACCGAGCTGACCTTCGTCACGCTGGCCGCGCGCCGCGAGGAGCCCGCGATCGCGGCCGCACTGCGGCTCGTCG
AGGCGCAGTGGGCCGGCTGA

Upstream 100 bases:

>100_bases
GCCGCCCGGCCGAGTATGGAATCGAAGCGTACCCGTGCCGCGCGCTCGCGATCCAATGAGTTATGCTCAACCGCATCATA
AGCCGCGCAAATATTGCTCG

Downstream 100 bases:

>100_bases
CACATCAATGCGGCCGCGCCGCGCGGACTTATCAACAGACGACGGGCTTTTCGACGGTGAACCCTGCGCTTCGCGCACGC
TCACCGCACCCCGCCGCCGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Xanthosine operon regulatory protein [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDLILLRAFAAVAREGNLTRAAAQLCLTQPAVSLQIKHLQQALGVALFARTSRGLGLTRDGQALLPHAERALAAAGEVLR
AASALRQEVRGRLRIGTVLDPEFLRLGGFLRQLVETHPRLETELRHGMSGWVRDAVRTRELDVGYSIGRPDDDDPHHGAL
FHTRTLTRYQYRVLAPAGWKERVQRARDWRALAALPWIWTPPSSAHHRLLSRRFAEAGVQPMKVAEVDQEPSMLDLVKSG
VGLTLARDSIALREAHAHALVIVEAVTVPTELTFVTLAARREEPAIAAALRLVEAQWAG

Sequences:

>Translated_299_residues
MDLILLRAFAAVAREGNLTRAAAQLCLTQPAVSLQIKHLQQALGVALFARTSRGLGLTRDGQALLPHAERALAAAGEVLR
AASALRQEVRGRLRIGTVLDPEFLRLGGFLRQLVETHPRLETELRHGMSGWVRDAVRTRELDVGYSIGRPDDDDPHHGAL
FHTRTLTRYQYRVLAPAGWKERVQRARDWRALAALPWIWTPPSSAHHRLLSRRFAEAGVQPMKVAEVDQEPSMLDLVKSG
VGLTLARDSIALREAHAHALVIVEAVTVPTELTFVTLAARREEPAIAAALRLVEAQWAG
>Mature_299_residues
MDLILLRAFAAVAREGNLTRAAAQLCLTQPAVSLQIKHLQQALGVALFARTSRGLGLTRDGQALLPHAERALAAAGEVLR
AASALRQEVRGRLRIGTVLDPEFLRLGGFLRQLVETHPRLETELRHGMSGWVRDAVRTRELDVGYSIGRPDDDDPHHGAL
FHTRTLTRYQYRVLAPAGWKERVQRARDWRALAALPWIWTPPSSAHHRLLSRRFAEAGVQPMKVAEVDQEPSMLDLVKSG
VGLTLARDSIALREAHAHALVIVEAVTVPTELTFVTLAARREEPAIAAALRLVEAQWAG

Specific function: Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=250, Percent_Identity=30.8, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082132, Length=153, Percent_Identity=32.0261437908497, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI157672245, Length=145, Percent_Identity=34.4827586206897, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=24.6913580246914, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=244, Percent_Identity=24.1803278688525, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788626, Length=150, Percent_Identity=32.6666666666667, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787601, Length=294, Percent_Identity=23.469387755102, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=245, Percent_Identity=24.0816326530612, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788887, Length=250, Percent_Identity=29.6, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787879, Length=100, Percent_Identity=40, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788296, Length=155, Percent_Identity=31.6129032258064, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87081904, Length=159, Percent_Identity=35.2201257861635, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32999; Mature: 32999

Theoretical pI: Translated: 10.76; Mature: 10.76

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLILLRAFAAVAREGNLTRAAAQLCLTQPAVSLQIKHLQQALGVALFARTSRGLGLTRD
CCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GQALLPHAERALAAAGEVLRAASALRQEVRGRLRIGTVLDPEFLRLGGFLRQLVETHPRL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHCCCH
ETELRHGMSGWVRDAVRTRELDVGYSIGRPDDDDPHHGALFHTRTLTRYQYRVLAPAGWK
HHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHEEEEEECCCCHH
ERVQRARDWRALAALPWIWTPPSSAHHRLLSRRFAEAGVQPMKVAEVDQEPSMLDLVKSG
HHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCC
VGLTLARDSIALREAHAHALVIVEAVTVPTELTFVTLAARREEPAIAAALRLVEAQWAG
CCEEEEHHHHHHHHHCCCEEEEEEEECCCCHHHEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLILLRAFAAVAREGNLTRAAAQLCLTQPAVSLQIKHLQQALGVALFARTSRGLGLTRD
CCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GQALLPHAERALAAAGEVLRAASALRQEVRGRLRIGTVLDPEFLRLGGFLRQLVETHPRL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHCCCH
ETELRHGMSGWVRDAVRTRELDVGYSIGRPDDDDPHHGALFHTRTLTRYQYRVLAPAGWK
HHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHEEEEEECCCCHH
ERVQRARDWRALAALPWIWTPPSSAHHRLLSRRFAEAGVQPMKVAEVDQEPSMLDLVKSG
HHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCC
VGLTLARDSIALREAHAHALVIVEAVTVPTELTFVTLAARREEPAIAAALRLVEAQWAG
CCEEEEHHHHHHHHHCCCEEEEEEEECCCCHHHEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2201776; 9205837; 9278503; 7559336 [H]