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The map label for this gene is srpA [H]

Identifier: 238025690

GI number: 238025690

Start: 10141

End: 11214

Strand: Reverse

Name: srpA [H]

Synonym: bglu_1g00120

Alternate gene names: 238025690

Gene position: 11214-10141 (Counterclockwise)

Preceding gene: 238025693

Following gene: 238025689

Centisome position: 0.29

GC content: 72.91

Gene sequence:

>1074_bases
ATGACGCATCCTCCCCCATCGAGCCCGCGCGGCGGCCAGGTCTGGCGCTGGGCCGTGATCGGCGGCACCGTCGCGGCCGC
CGCCGCCGCGTTCGGCTACACCGCCGGCTGGCTCGCGCCGCACCGGCTCACGCCGCAGCGCATCGTCGCCGCGCTGCAGG
CCAACGGCGGCTTGCATCCCGGCTTCCGCCGCAACCACGCCAAGGGCATCTGCGTGACCGGCTACTTCGAGAGCAACGGC
GACGGCGCCGCATGGTCCAGCGCGCCGTTCTTCGGCGCCGGCGTGCGCACGCCCGTGGTCGGGCGCTTCGCGCTGCCCGG
CGGCAACCCTTATGCGCCCGACACCAGCGTGCCGATCCGCAGCCTCGCGCTGCGGTTGACCGCGCCCGACGGCGAGCAAT
GGCGCACCGGCATGAACGCGATGCCGGTGTTCCCGGTCGCGACGCCGCGCGCGTTCTACGAGCAGACCGTCGCGACGCGG
CCCGATCCCGCCACCGGCAAGCCCGATCCGAAGAAGGTCGGGGCGTTCTTCGCCGCGCATCCGGAGACCGCCGCGTTCCG
CGCCTGGGTGAAGACCGCCAAGCCGAGCGCGAGCTTTGCCACCGAGACCTATTACGGCATCAACGCGTTTTATTTCGTGG
ACGCGCAGGGCATGAAGCACGCGGTGCGCTGGCGCGTGGTGCCCGAGCAGACCGACGGCGCCGGCGTGGCGAGCGGCGCG
AACGTGCTGCAAGCGGATCTGGCCGAGCGGCTCGGCAGCGGGCCGCAGCGCTGGCACTGGCTCGTGACGTTCGCGAACCC
AGGCGACCCCGTGAACGACGCGACGCGCAACTGGCCCGCCGATCGCAAGACCCTCGACATCGGCACGCTGGTGCTCGACC
GCGCCGAGGCGCAGGACAGCGGGCCGTGCCGCGACATCAACTACGACCCGACGGTACTGCCGACGGGCATCGAGCCGTCC
GGCGACCCGCTGCTGGCGGCGCGCTCGGCGGCCTATGCCGATTCGTACAAGCTGCGCACCAGCGAGGAAGCCGGCGTGCC
CGGTTATGCCCGCGCCGCGCCGGAGGCACGATGA

Upstream 100 bases:

>100_bases
TCTGCCGGGGCCGCGGAATGCGTGGCGGCCGTGGAATAAACCGCCGGGCCGGTCGTCTCATCCGAGTCCCCTCAACGACC
GAAGGTCAGGAGCGAATTCC

Downstream 100 bases:

>100_bases
TGAACCCCACTTCCTCTCCTTCGGGATTCAGCCCGCTCGCGCGGGCGCTGCACTGGCTGATGGCCATGCTGATCATCGCG
ATGCTGTTCATCGGGGTGGG

Product: Catalase

Products: O2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MTHPPPSSPRGGQVWRWAVIGGTVAAAAAAFGYTAGWLAPHRLTPQRIVAALQANGGLHPGFRRNHAKGICVTGYFESNG
DGAAWSSAPFFGAGVRTPVVGRFALPGGNPYAPDTSVPIRSLALRLTAPDGEQWRTGMNAMPVFPVATPRAFYEQTVATR
PDPATGKPDPKKVGAFFAAHPETAAFRAWVKTAKPSASFATETYYGINAFYFVDAQGMKHAVRWRVVPEQTDGAGVASGA
NVLQADLAERLGSGPQRWHWLVTFANPGDPVNDATRNWPADRKTLDIGTLVLDRAEAQDSGPCRDINYDPTVLPTGIEPS
GDPLLAARSAAYADSYKLRTSEEAGVPGYARAAPEAR

Sequences:

>Translated_357_residues
MTHPPPSSPRGGQVWRWAVIGGTVAAAAAAFGYTAGWLAPHRLTPQRIVAALQANGGLHPGFRRNHAKGICVTGYFESNG
DGAAWSSAPFFGAGVRTPVVGRFALPGGNPYAPDTSVPIRSLALRLTAPDGEQWRTGMNAMPVFPVATPRAFYEQTVATR
PDPATGKPDPKKVGAFFAAHPETAAFRAWVKTAKPSASFATETYYGINAFYFVDAQGMKHAVRWRVVPEQTDGAGVASGA
NVLQADLAERLGSGPQRWHWLVTFANPGDPVNDATRNWPADRKTLDIGTLVLDRAEAQDSGPCRDINYDPTVLPTGIEPS
GDPLLAARSAAYADSYKLRTSEEAGVPGYARAAPEAR
>Mature_356_residues
THPPPSSPRGGQVWRWAVIGGTVAAAAAAFGYTAGWLAPHRLTPQRIVAALQANGGLHPGFRRNHAKGICVTGYFESNGD
GAAWSSAPFFGAGVRTPVVGRFALPGGNPYAPDTSVPIRSLALRLTAPDGEQWRTGMNAMPVFPVATPRAFYEQTVATRP
DPATGKPDPKKVGAFFAAHPETAAFRAWVKTAKPSASFATETYYGINAFYFVDAQGMKHAVRWRVVPEQTDGAGVASGAN
VLQADLAERLGSGPQRWHWLVTFANPGDPVNDATRNWPADRKTLDIGTLVLDRAEAQDSGPCRDINYDPTVLPTGIEPSG
DPLLAARSAAYADSYKLRTSEEAGVPGYARAAPEAR

Specific function: Decomposes Hydrogen Peroxide Into Water And Oxygen; Serves To Protect Cells From The Toxic Effects Of Hydrogen Peroxide. [C]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=294, Percent_Identity=27.891156462585, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71998444, Length=299, Percent_Identity=25.752508361204, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020835
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase [H]

EC number: 1.11.1.6

Molecular weight: Translated: 37976; Mature: 37845

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPPPSSPRGGQVWRWAVIGGTVAAAAAAFGYTAGWLAPHRLTPQRIVAALQANGGLHP
CCCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHCCCCCCC
GFRRNHAKGICVTGYFESNGDGAAWSSAPFFGAGVRTPVVGRFALPGGNPYAPDTSVPIR
CCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCE
SLALRLTAPDGEQWRTGMNAMPVFPVATPRAFYEQTVATRPDPATGKPDPKKVGAFFAAH
EEEEEEECCCCHHHHCCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHCEEEECC
PETAAFRAWVKTAKPSASFATETYYGINAFYFVDAQGMKHAVRWRVVPEQTDGAGVASGA
CCHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCH
NVLQADLAERLGSGPQRWHWLVTFANPGDPVNDATRNWPADRKTLDIGTLVLDRAEAQDS
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHCCCCCCCCEEEHHHEEEECCCCCCC
GPCRDINYDPTVLPTGIEPSGDPLLAARSAAYADSYKLRTSEEAGVPGYARAAPEAR
CCCCCCCCCCCEEECCCCCCCCCEEEHHHHHHCCCEEEECCCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
THPPPSSPRGGQVWRWAVIGGTVAAAAAAFGYTAGWLAPHRLTPQRIVAALQANGGLHP
CCCCCCCCCCCCEEEEEEECCHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHCCCCCCC
GFRRNHAKGICVTGYFESNGDGAAWSSAPFFGAGVRTPVVGRFALPGGNPYAPDTSVPIR
CCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCE
SLALRLTAPDGEQWRTGMNAMPVFPVATPRAFYEQTVATRPDPATGKPDPKKVGAFFAAH
EEEEEEECCCCHHHHCCCCCCCEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHCEEEECC
PETAAFRAWVKTAKPSASFATETYYGINAFYFVDAQGMKHAVRWRVVPEQTDGAGVASGA
CCHHHHHHHHHHCCCCCCCCCEEEECCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCH
NVLQADLAERLGSGPQRWHWLVTFANPGDPVNDATRNWPADRKTLDIGTLVLDRAEAQDS
HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHCCCCCCCCEEEHHHEEEECCCCCCC
GPCRDINYDPTVLPTGIEPSGDPLLAARSAAYADSYKLRTSEEAGVPGYARAAPEAR
CCCCCCCCCCCEEECCCCCCCCCEEEHHHHHHCCCEEEECCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Heme Group. [C]

Metal ions: NA

Kcat value (1/min): 980000 [C]

Specific activity: NA

Km value (mM): 18.2 {H2O2}} 10 {H2O2}} 3.7 {H2O2}} [C]

Substrates: H2O2

Specific reaction: 2 H2O2 = O2 + 2 H2O

General reaction: Redox reaction [C]

Inhibitor: 3-Amino-1-H-1, 2, 4-triazolecoli, Rhodopseudomonascapsulata; Dianisidine; H2O2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7536734 [H]