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The map label for this gene is tcp [H]

Identifier: 238025427

GI number: 238025427

Start: 2622095

End: 2623717

Strand: Direct

Name: tcp [H]

Synonym: bglu_2g21170

Alternate gene names: 238025427

Gene position: 2622095-2623717 (Clockwise)

Preceding gene: 238025414

Following gene: 238025428

Centisome position: 92.74

GC content: 66.91

Gene sequence:

>1623_bases
ATGAAAATTTCCGACTTGAAAATCGGGGTTCGTTTAAGCGCGGCATTCGGAATCGTCGTCTTGCTGCTGATCGGCACGAC
GTTGCTCGGCATCCGCCACATCGAATCGAGCGTCGACCGCATGAACGGCATCGTCGGTCAGCGTTATTCGCTAATCGCCG
CCAGCAGTCAGATCAAGAACAACGGCTACAAGGCCAACGCCATTCTCAGCCACCTGCTGCTGGCCACCACGGCGGACCAG
GCGAAACGGTACATGGATGACTATGCCGTCATCCGCAAGTTGAACGCCGACACTTACGCGAAATTCGAAAAGCAGCTGAC
CGACGAGCCGAGCCGCGCGCTGTTCAGGAGTCAGTTCGAAGCGCGCAGCGCCTACGGCCAGAGCGTCAAGAAATTCTTCG
AGCTGGTGGCCGCCAACGATCGTAACGGCGCGCGCGACCTCTACCAGGGCGACATGGCGCGTCTGCAGGACGACTACTAC
ACGCTGGTCGACAAGATGGTCGACTTCCAGGCGGCCCAGATGAACAACGACGTCGCCGAGGCCACGGCCGAGGGCCACTG
GGCCAAGCTGCAGATGGGCGTCATCGCGCTCTGCGCGCTGGTGGCCTCGGTGCTGACCGGCTGGTTCATCACGCGCAGCA
TCACCCGGCCGATCCACGGCGCGGTGGCGCTGGCCGAGGCCGTGGCGAGCGGCGACCTCACGCATCGGCTCGACGTGACG
GGCCGCGACGAGGTCTCGCGCCTGCTGGTCGCGCTCGGCAAGATGATCGAGGGCCTCAACACCATCGTCGGCAACGTGCG
CGGCGGCACCCACGCCATCACGCTCGCCTCGCAGGAAGTGGCGAGCGGCAACATGGATCTCTCCACGCGCACCGAGCAGC
AGGCGAGCGCGCTGGAACAGACCGCCGCCGCGATGGAGCAGCTCACCTCCACCGTCAAGCAGAACGCCAGCAACGCGCAG
CAGGCCAACCAGATCGCGGGCGACGCCTCGGCGGTGGCCGTGAAGGGCGGCGAGGCGGTAGACCGCGTGGTGGACACCAT
GAACGCGATCGATGCCTCCTCGCGCAAGGTGGTGGAGATCATCGGCGTGATCGAGGGCATCGCGTTCCAGACCAACATCC
TCGCGCTGAACGCGGCGGTGGAGGCCGCGCGCGCCGGCGAGAACGGCCGCGGCTTCGCGGTGGTGGCGGGCGAGGTGCGC
AGCCTCGCGCAGCGCAGCGCGGTGGCGGCCAAGGAGATCAAGACGCTGATCGACGATTCGGTCAGCCACGTCGGGGTGGG
CACCGGCATCGTCGAGCAGGCCGGCGAGACGATCCGGCAGGTGGTCAAGAGCATCACGGCGGTGTCGTCGATCGTCAACG
AGATGAGCGCGTCGAGCCGCGAGCAGAGCGACGGCATCGAGCAGATCAACCACGCCATCACGCAGATGGATCAGGTCACG
CAGGAGAACGCGGCGCTGGTCGAGGAAAGCGCCGCGGCGGCGCAGGCGCTGCGCAACCAGGCCGACGCGCTGGCCGATAC
CGTGGCCGCGTTCCGGCTCGAAGGCGACGCGCGCCGCCCCGTCACCGCGGCGGCCCGACCCTCGCAACGGGCGACCCCCA
TGCCCATGCTCTCCGTCACCTGA

Upstream 100 bases:

>100_bases
CATCGACGACTGATAAAGACGCAGTCTGGTGGTGGCGGGTTCGGTCCCCGAAGAAAGGAATGCACTATTAAAAAAGGTGT
TCTTGACAAGGAAATGCACC

Downstream 100 bases:

>100_bases
GAGCCGGTCGCTCCCGGCATCAGAAACGCAGACACGGCCCGAAGCACGGGCCGCTGCCGCATGCCGGAGCGTCGATGCCA
AGCAGGGCAGGCGCTCCGGC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MKISDLKIGVRLSAAFGIVVLLLIGTTLLGIRHIESSVDRMNGIVGQRYSLIAASSQIKNNGYKANAILSHLLLATTADQ
AKRYMDDYAVIRKLNADTYAKFEKQLTDEPSRALFRSQFEARSAYGQSVKKFFELVAANDRNGARDLYQGDMARLQDDYY
TLVDKMVDFQAAQMNNDVAEATAEGHWAKLQMGVIALCALVASVLTGWFITRSITRPIHGAVALAEAVASGDLTHRLDVT
GRDEVSRLLVALGKMIEGLNTIVGNVRGGTHAITLASQEVASGNMDLSTRTEQQASALEQTAAAMEQLTSTVKQNASNAQ
QANQIAGDASAVAVKGGEAVDRVVDTMNAIDASSRKVVEIIGVIEGIAFQTNILALNAAVEAARAGENGRGFAVVAGEVR
SLAQRSAVAAKEIKTLIDDSVSHVGVGTGIVEQAGETIRQVVKSITAVSSIVNEMSASSREQSDGIEQINHAITQMDQVT
QENAALVEESAAAAQALRNQADALADTVAAFRLEGDARRPVTAAARPSQRATPMPMLSVT

Sequences:

>Translated_540_residues
MKISDLKIGVRLSAAFGIVVLLLIGTTLLGIRHIESSVDRMNGIVGQRYSLIAASSQIKNNGYKANAILSHLLLATTADQ
AKRYMDDYAVIRKLNADTYAKFEKQLTDEPSRALFRSQFEARSAYGQSVKKFFELVAANDRNGARDLYQGDMARLQDDYY
TLVDKMVDFQAAQMNNDVAEATAEGHWAKLQMGVIALCALVASVLTGWFITRSITRPIHGAVALAEAVASGDLTHRLDVT
GRDEVSRLLVALGKMIEGLNTIVGNVRGGTHAITLASQEVASGNMDLSTRTEQQASALEQTAAAMEQLTSTVKQNASNAQ
QANQIAGDASAVAVKGGEAVDRVVDTMNAIDASSRKVVEIIGVIEGIAFQTNILALNAAVEAARAGENGRGFAVVAGEVR
SLAQRSAVAAKEIKTLIDDSVSHVGVGTGIVEQAGETIRQVVKSITAVSSIVNEMSASSREQSDGIEQINHAITQMDQVT
QENAALVEESAAAAQALRNQADALADTVAAFRLEGDARRPVTAAARPSQRATPMPMLSVT
>Mature_540_residues
MKISDLKIGVRLSAAFGIVVLLLIGTTLLGIRHIESSVDRMNGIVGQRYSLIAASSQIKNNGYKANAILSHLLLATTADQ
AKRYMDDYAVIRKLNADTYAKFEKQLTDEPSRALFRSQFEARSAYGQSVKKFFELVAANDRNGARDLYQGDMARLQDDYY
TLVDKMVDFQAAQMNNDVAEATAEGHWAKLQMGVIALCALVASVLTGWFITRSITRPIHGAVALAEAVASGDLTHRLDVT
GRDEVSRLLVALGKMIEGLNTIVGNVRGGTHAITLASQEVASGNMDLSTRTEQQASALEQTAAAMEQLTSTVKQNASNAQ
QANQIAGDASAVAVKGGEAVDRVVDTMNAIDASSRKVVEIIGVIEGIAFQTNILALNAAVEAARAGENGRGFAVVAGEVR
SLAQRSAVAAKEIKTLIDDSVSHVGVGTGIVEQAGETIRQVVKSITAVSSIVNEMSASSREQSDGIEQINHAITQMDQVT
QENAALVEESAAAAQALRNQADALADTVAAFRLEGDARRPVTAAARPSQRATPMPMLSVT

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=393, Percent_Identity=45.8015267175573, Blast_Score=301, Evalue=8e-83,
Organism=Escherichia coli, GI1788195, Length=330, Percent_Identity=54.8484848484848, Blast_Score=301, Evalue=1e-82,
Organism=Escherichia coli, GI2367378, Length=417, Percent_Identity=46.7625899280576, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1788194, Length=354, Percent_Identity=47.7401129943503, Blast_Score=292, Evalue=4e-80,
Organism=Escherichia coli, GI1789453, Length=316, Percent_Identity=39.5569620253165, Blast_Score=206, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57397; Mature: 57397

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISDLKIGVRLSAAFGIVVLLLIGTTLLGIRHIESSVDRMNGIVGQRYSLIAASSQIKN
CCCCCEEECEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NGYKANAILSHLLLATTADQAKRYMDDYAVIRKLNADTYAKFEKQLTDEPSRALFRSQFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
ARSAYGQSVKKFFELVAANDRNGARDLYQGDMARLQDDYYTLVDKMVDFQAAQMNNDVAE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ATAEGHWAKLQMGVIALCALVASVLTGWFITRSITRPIHGAVALAEAVASGDLTHRLDVT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
GRDEVSRLLVALGKMIEGLNTIVGNVRGGTHAITLASQEVASGNMDLSTRTEQQASALEQ
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCCCHHHHHHHHHH
TAAAMEQLTSTVKQNASNAQQANQIAGDASAVAVKGGEAVDRVVDTMNAIDASSRKVVEI
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHH
IGVIEGIAFQTNILALNAAVEAARAGENGRGFAVVAGEVRSLAQRSAVAAKEIKTLIDDS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
VSHVGVGTGIVEQAGETIRQVVKSITAVSSIVNEMSASSREQSDGIEQINHAITQMDQVT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QENAALVEESAAAAQALRNQADALADTVAAFRLEGDARRPVTAAARPSQRATPMPMLSVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKISDLKIGVRLSAAFGIVVLLLIGTTLLGIRHIESSVDRMNGIVGQRYSLIAASSQIKN
CCCCCEEECEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NGYKANAILSHLLLATTADQAKRYMDDYAVIRKLNADTYAKFEKQLTDEPSRALFRSQFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
ARSAYGQSVKKFFELVAANDRNGARDLYQGDMARLQDDYYTLVDKMVDFQAAQMNNDVAE
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ATAEGHWAKLQMGVIALCALVASVLTGWFITRSITRPIHGAVALAEAVASGDLTHRLDVT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
GRDEVSRLLVALGKMIEGLNTIVGNVRGGTHAITLASQEVASGNMDLSTRTEQQASALEQ
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCCCCCHHHHHHHHHH
TAAAMEQLTSTVKQNASNAQQANQIAGDASAVAVKGGEAVDRVVDTMNAIDASSRKVVEI
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHH
IGVIEGIAFQTNILALNAAVEAARAGENGRGFAVVAGEVRSLAQRSAVAAKEIKTLIDDS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
VSHVGVGTGIVEQAGETIRQVVKSITAVSSIVNEMSASSREQSDGIEQINHAITQMDQVT
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
QENAALVEESAAAAQALRNQADALADTVAAFRLEGDARRPVTAAARPSQRATPMPMLSVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]