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The map label for this gene is pheA [H]

Identifier: 238025327

GI number: 238025327

Start: 2488187

End: 2489323

Strand: Direct

Name: pheA [H]

Synonym: bglu_2g20010

Alternate gene names: 238025327

Gene position: 2488187-2489323 (Clockwise)

Preceding gene: 238025326

Following gene: 238025328

Centisome position: 88.0

GC content: 70.8

Gene sequence:

>1137_bases
ATGCCTCTTTCCGACACCGCCTCGCCCGCTCACGACCCGGTCGCCCTGCAGCGCGCGCAGATCGATGCAATCGACCACGA
ACTGCTCGCGCTGATCGCGCGCCGGATGCAGCACGCCGCCGAGATCGGCCGCGTCAAGGCGTGTGACGGCCGGACCATCC
GCCAGCCGGCGAGGGAAACGGAAATCGTCGCGGGGCTGTGCACTCGGCCGCTCGGCTTGCTGCGGGAGCGCCACGTCGCG
GCGATCTGGCAAACGCTGTTCCGCGTCAGCCGCGAGGTGCAGCAAGCGCCGTCGATTGCGTTCCTGGGCCCGTCCGGCAC
CTTCACCGAAACCGCCATGCAGCGCTACTTCGGCGATCCGATCCGCCCCCTCGCATGCGACACGCTCGAGGCGACCTTCG
CGGCACTGGCGGCAGCCAAGGTCGAACATGCGGTGGTGCCGATCGAGAATTCGACCGAAGGCACCGTCAGTCGCACGCTG
GACCTGCTGGCCGAGGCAAGCGCTCCGATCGTCGGCGAGGTCGTGCTGCCGGTCGCCCACTGTCTGCTGAGCGCATCCGG
CACGCTCGACGGCGTCGATTGCGTGCTCGGTCACCAGCAAGCGCTGGCGCAGTGTCGCGCGTGGCTCGACGCGCACGCCC
CGCAGTTGCGCCGTGTCCCGGTCGCGAGCAACGCGGCGGCGGCCCGCGAGGCGGCCAGCATGACGGATTGCGCCGCCATC
GCCGGCGAACCGGCGGCCGACCGATACGGCTTACGGATCGTGGCGAACGCGATCCAGGACGAGCCCGGCAATCGCACTCG
CTTCGTCGTGCTCGGCGGGCCACCGGCCGAGCCGACAGGCCACGACCGCACCAGCCTGATGCTGCAGCTCAACGATAGGA
TCGGCGCGCTCGCGCGCGTGTTCGACGCGTTGGCTCGGCACCGGATCTCGGTGCTGTGGCTCGATTCGCGTCCCGGCCGC
ACCGCGGGGTGGGCATACCGCTTCTTCATCGACATTGACGGCCACCAGAACGACACGCACGTCGGCGCCGCCCTGCACGA
TATCGGCACGATCGCCGCCGACCTGCGAATCTTCGGCTCCTACCCGCGCGCGCCGCTCGCCGGCTGCCGCGCCGCCGCCG
AGCCGGGCGCGGCATGA

Upstream 100 bases:

>100_bases
CGCTCGAACGCGTTCATGAAGCGTCCGAGCGCATCGGCCGGCCGGCCCTCGCGCGCTGAGCGCACACCGCCCTTCCCTTC
GCTACCTTCACGGTCCCGTC

Downstream 100 bases:

>100_bases
GCGCAGTCGCCACCCGGGCCGCCGTCGCGCGGCGGGTACGGGCCATCTGCGAAGGCCATGACGATCGCCTGCTGGTGCTG
CTCGGTGTCGCAACGCCGTC

Product: Prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MPLSDTASPAHDPVALQRAQIDAIDHELLALIARRMQHAAEIGRVKACDGRTIRQPARETEIVAGLCTRPLGLLRERHVA
AIWQTLFRVSREVQQAPSIAFLGPSGTFTETAMQRYFGDPIRPLACDTLEATFAALAAAKVEHAVVPIENSTEGTVSRTL
DLLAEASAPIVGEVVLPVAHCLLSASGTLDGVDCVLGHQQALAQCRAWLDAHAPQLRRVPVASNAAAAREAASMTDCAAI
AGEPAADRYGLRIVANAIQDEPGNRTRFVVLGGPPAEPTGHDRTSLMLQLNDRIGALARVFDALARHRISVLWLDSRPGR
TAGWAYRFFIDIDGHQNDTHVGAALHDIGTIAADLRIFGSYPRAPLAGCRAAAEPGAA

Sequences:

>Translated_378_residues
MPLSDTASPAHDPVALQRAQIDAIDHELLALIARRMQHAAEIGRVKACDGRTIRQPARETEIVAGLCTRPLGLLRERHVA
AIWQTLFRVSREVQQAPSIAFLGPSGTFTETAMQRYFGDPIRPLACDTLEATFAALAAAKVEHAVVPIENSTEGTVSRTL
DLLAEASAPIVGEVVLPVAHCLLSASGTLDGVDCVLGHQQALAQCRAWLDAHAPQLRRVPVASNAAAAREAASMTDCAAI
AGEPAADRYGLRIVANAIQDEPGNRTRFVVLGGPPAEPTGHDRTSLMLQLNDRIGALARVFDALARHRISVLWLDSRPGR
TAGWAYRFFIDIDGHQNDTHVGAALHDIGTIAADLRIFGSYPRAPLAGCRAAAEPGAA
>Mature_377_residues
PLSDTASPAHDPVALQRAQIDAIDHELLALIARRMQHAAEIGRVKACDGRTIRQPARETEIVAGLCTRPLGLLRERHVAA
IWQTLFRVSREVQQAPSIAFLGPSGTFTETAMQRYFGDPIRPLACDTLEATFAALAAAKVEHAVVPIENSTEGTVSRTLD
LLAEASAPIVGEVVLPVAHCLLSASGTLDGVDCVLGHQQALAQCRAWLDAHAPQLRRVPVASNAAAAREAASMTDCAAIA
GEPAADRYGLRIVANAIQDEPGNRTRFVVLGGPPAEPTGHDRTSLMLQLNDRIGALARVFDALARHRISVLWLDSRPGRT
AGWAYRFFIDIDGHQNDTHVGAALHDIGTIAADLRIFGSYPRAPLAGCRAAAEPGAA

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=379, Percent_Identity=29.8153034300792, Blast_Score=161, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6324013, Length=321, Percent_Identity=27.1028037383178, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 40291; Mature: 40160

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSDTASPAHDPVALQRAQIDAIDHELLALIARRMQHAAEIGRVKACDGRTIRQPARET
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHCCHHHH
EIVAGLCTRPLGLLRERHVAAIWQTLFRVSREVQQAPSIAFLGPSGTFTETAMQRYFGDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCC
IRPLACDTLEATFAALAAAKVEHAVVPIENSTEGTVSRTLDLLAEASAPIVGEVVLPVAH
CCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
CLLSASGTLDGVDCVLGHQQALAQCRAWLDAHAPQLRRVPVASNAAAAREAASMTDCAAI
HHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHH
AGEPAADRYGLRIVANAIQDEPGNRTRFVVLGGPPAEPTGHDRTSLMLQLNDRIGALARV
CCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECHHHHHHHHH
FDALARHRISVLWLDSRPGRTAGWAYRFFIDIDGHQNDTHVGAALHDIGTIAADLRIFGS
HHHHHHCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
YPRAPLAGCRAAAEPGAA
CCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
PLSDTASPAHDPVALQRAQIDAIDHELLALIARRMQHAAEIGRVKACDGRTIRQPARET
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHCCHHHH
EIVAGLCTRPLGLLRERHVAAIWQTLFRVSREVQQAPSIAFLGPSGTFTETAMQRYFGDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCC
IRPLACDTLEATFAALAAAKVEHAVVPIENSTEGTVSRTLDLLAEASAPIVGEVVLPVAH
CCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
CLLSASGTLDGVDCVLGHQQALAQCRAWLDAHAPQLRRVPVASNAAAAREAASMTDCAAI
HHHHCCCCCCCHHHHHCHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHH
AGEPAADRYGLRIVANAIQDEPGNRTRFVVLGGPPAEPTGHDRTSLMLQLNDRIGALARV
CCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECHHHHHHHHH
FDALARHRISVLWLDSRPGRTAGWAYRFFIDIDGHQNDTHVGAALHDIGTIAADLRIFGS
HHHHHHCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCC
YPRAPLAGCRAAAEPGAA
CCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]