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The map label for this gene is glsA [H]

Identifier: 238025152

GI number: 238025152

Start: 2271725

End: 2272639

Strand: Direct

Name: glsA [H]

Synonym: bglu_2g18170

Alternate gene names: 238025152

Gene position: 2271725-2272639 (Clockwise)

Preceding gene: 238025149

Following gene: 238025158

Centisome position: 80.35

GC content: 68.63

Gene sequence:

>915_bases
ATGAATTACCCATCGATACTCGAACGCATCCGCACCGAAATCACGCCGTGGATCGGCGCCGGCCGCGTGGCCGACTACAT
CCCCGAGCTCGCGAAGGTTCCGGCCGAGCGCTTCGGCATCGCGATCGTCACGCTCGACGGCCAGACCCACACGGTGGGCG
ACGCGCACGAGCGCTTCTCGATCCAGAGCATCTCGAAGCTGTTCGCCTGCACGCTCGCGTTCCAGCTGCTCGGCGACGAG
CTCTGGCAGCGCGTGGGGCGCGAGCCGTCGGGCACCGCGTTCAATTCGCTGGTGCAGCTCGAAAGCGAGCGCGGCAAGCC
GCGCAACCCGTTCATCAACGCCGGCGCACTGGTGGTCACCGACGTGCTGAGCCGCCGCTTCGTGCGCGCCGAGACAGCGC
TCGTCGAATTCATCCGCCGGCTGATCGGCTCGAACGAGATCGACTACGACCTGCGCGTGGCGCAGTCCGAATGGCAGCAC
GCCGAGCGCAACCGCGCGATGGCCCACTTCATGGCCAGCTTCGGCAACATGTGGATGCCGCCCGACATGGTGGTGGAAGC
CTACTGCCGGCAGTGCGCGATCTCGATGAACTGCGTGGAGCTCGCGCAGGCCGCGCTGTTCCTCGCCAACGGCGGCGTGG
CGCCCGTGACCGGCGAGCGCGTGGTGGACGCGAGTTCGGCCAAGCGGCTGTCCGCGCTGATGCTGACCTGCGGCACCTAC
GACGCGGCCGGCGACTTCGTCTACCGCGTCGGGCTGCCGGCCAAGAGCGGCGTGGGCGGCGGCATCGTGGCGGTGCTGCC
GGGCGAGATGGCCGTCTGCGTCTGGTCGCCGGGGCTCGACGCGAACGGCAATTCGCTGGCCGGCGTGCTGGCGCTGGAAT
GGCTGACGAGCTACACGGAACGCTCGATCTTCTGA

Upstream 100 bases:

>100_bases
GGCCGCCACGGCAGCGGCTCCGAGCTTGACGAATCGCGGCGCAAGCGGTTCCATACGGGCTCGCTGAATTCGGCGCCGCG
CGCGCCGCCCGATCGCCGTC

Downstream 100 bases:

>100_bases
GGCCGCGCGGGCCGCGGATTGCGGCGGCCCGCGCCCGGCTCCGGCGCCGCCCGCCGGCCTCGCCGTCAGGACGCGGCGCG
CCGCCCCGGCCGCCGCGATG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNYPSILERIRTEITPWIGAGRVADYIPELAKVPAERFGIAIVTLDGQTHTVGDAHERFSIQSISKLFACTLAFQLLGDE
LWQRVGREPSGTAFNSLVQLESERGKPRNPFINAGALVVTDVLSRRFVRAETALVEFIRRLIGSNEIDYDLRVAQSEWQH
AERNRAMAHFMASFGNMWMPPDMVVEAYCRQCAISMNCVELAQAALFLANGGVAPVTGERVVDASSAKRLSALMLTCGTY
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWSPGLDANGNSLAGVLALEWLTSYTERSIF

Sequences:

>Translated_304_residues
MNYPSILERIRTEITPWIGAGRVADYIPELAKVPAERFGIAIVTLDGQTHTVGDAHERFSIQSISKLFACTLAFQLLGDE
LWQRVGREPSGTAFNSLVQLESERGKPRNPFINAGALVVTDVLSRRFVRAETALVEFIRRLIGSNEIDYDLRVAQSEWQH
AERNRAMAHFMASFGNMWMPPDMVVEAYCRQCAISMNCVELAQAALFLANGGVAPVTGERVVDASSAKRLSALMLTCGTY
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWSPGLDANGNSLAGVLALEWLTSYTERSIF
>Mature_304_residues
MNYPSILERIRTEITPWIGAGRVADYIPELAKVPAERFGIAIVTLDGQTHTVGDAHERFSIQSISKLFACTLAFQLLGDE
LWQRVGREPSGTAFNSLVQLESERGKPRNPFINAGALVVTDVLSRRFVRAETALVEFIRRLIGSNEIDYDLRVAQSEWQH
AERNRAMAHFMASFGNMWMPPDMVVEAYCRQCAISMNCVELAQAALFLANGGVAPVTGERVVDASSAKRLSALMLTCGTY
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWSPGLDANGNSLAGVLALEWLTSYTERSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=275, Percent_Identity=39.6363636363636, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI20336214, Length=296, Percent_Identity=34.7972972972973, Blast_Score=180, Evalue=2e-45,
Organism=Escherichia coli, GI1787804, Length=301, Percent_Identity=54.1528239202658, Blast_Score=316, Evalue=1e-87,
Organism=Escherichia coli, GI1786693, Length=272, Percent_Identity=39.7058823529412, Blast_Score=202, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17507019, Length=297, Percent_Identity=38.3838383838384, Blast_Score=199, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17532727, Length=306, Percent_Identity=36.6013071895425, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI193204073, Length=281, Percent_Identity=37.0106761565836, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI193204075, Length=283, Percent_Identity=36.7491166077738, Blast_Score=181, Evalue=3e-46,
Organism=Drosophila melanogaster, GI281363241, Length=289, Percent_Identity=37.0242214532872, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653162, Length=289, Percent_Identity=37.0242214532872, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI281363239, Length=289, Percent_Identity=37.0242214532872, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653166, Length=289, Percent_Identity=37.0242214532872, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653164, Length=289, Percent_Identity=37.0242214532872, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653158, Length=289, Percent_Identity=37.0242214532872, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653156, Length=289, Percent_Identity=37.0242214532872, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI116008307, Length=289, Percent_Identity=37.0242214532872, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33105; Mature: 33105

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYPSILERIRTEITPWIGAGRVADYIPELAKVPAERFGIAIVTLDGQTHTVGDAHERFS
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHCEEEEEECCCCCCCCCHHHHHH
IQSISKLFACTLAFQLLGDELWQRVGREPSGTAFNSLVQLESERGKPRNPFINAGALVVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
DVLSRRFVRAETALVEFIRRLIGSNEIDYDLRVAQSEWQHAERNRAMAHFMASFGNMWMP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PDMVVEAYCRQCAISMNCVELAQAALFLANGGVAPVTGERVVDASSAKRLSALMLTCGTY
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCC
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWSPGLDANGNSLAGVLALEWLTSYTE
CCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
RSIF
HCCC
>Mature Secondary Structure
MNYPSILERIRTEITPWIGAGRVADYIPELAKVPAERFGIAIVTLDGQTHTVGDAHERFS
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHCEEEEEECCCCCCCCCHHHHHH
IQSISKLFACTLAFQLLGDELWQRVGREPSGTAFNSLVQLESERGKPRNPFINAGALVVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
DVLSRRFVRAETALVEFIRRLIGSNEIDYDLRVAQSEWQHAERNRAMAHFMASFGNMWMP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PDMVVEAYCRQCAISMNCVELAQAALFLANGGVAPVTGERVVDASSAKRLSALMLTCGTY
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCC
DAAGDFVYRVGLPAKSGVGGGIVAVLPGEMAVCVWSPGLDANGNSLAGVLALEWLTSYTE
CCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
RSIF
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA