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The map label for this gene is idnD [H]

Identifier: 238024734

GI number: 238024734

Start: 1757535

End: 1758605

Strand: Reverse

Name: idnD [H]

Synonym: bglu_2g13710

Alternate gene names: 238024734

Gene position: 1758605-1757535 (Counterclockwise)

Preceding gene: 238024735

Following gene: 238024733

Centisome position: 62.2

GC content: 72.92

Gene sequence:

>1071_bases
ATGAGACTGCGCTGCATGTGTCTCGTCATTCACGCGCCGAACGATCTGCGCTACGAGCCGGCCGAGGTCGAGGCGCCCGG
CCCGGGGCAGGTGCGCGTGCAGGTCGCGATGGGCGGCATCTGCGGCTCGGACCTGCATTACTTCCGCCACGGCGGGTTCG
GCGCGATCCGCTTGCAGCAGCCGATGATTCTCGGCCACGAGGTGGCGGGCACGGTGGTCGAGACCGGCGAGGGCGTGAGC
GGCGTGCGGGTGGGCGAGCGCGTGGCGGTCAACCCGAGCCGGCCCTGCGGCGCGTGCCGATACTGCCTCGAAGGGCTGCC
GAACCAGTGTCTCGACATGCGCTTCTACGGTAGCGCGATGCGCATGCCGCACATCCAGGGCGCGTTTCGCGGCGTGCTGG
TCTGCGATGCGGCGCAGTGCGCGAAGCTGGCCGACCAGGTGCCGTTCTCGATCGCCGCGCTGGCCGAGCCGTTCGCGGTC
GGCCTGCACGCCGTGTCGCGCGCCGGCGCGCTGCTCGGGCGGCGCGTGCTGGTGTCCGGCTGCGGGCCGATCGGCGCGCT
GGTGGCGGCGGCGGCCCGTGTCCACGGCGCGCGCGAGGTGGTGGCCACCGACGTGGTGGACGAGCCGCTCGCGGTGGCCA
AGGCGCTCGGCGCGGATCGCGCGATCAACGTCGCGGCCGATCCCGACTGGACGAAGTCGTTCGCGGCCGACAAGGGCAGC
TTCGACGTGGTGATCGAGTGCTCGGGCAGCGAGCGCGCGCTGCGCGACGGGCTCGAGGTGCTGCGTCCGCGCGGCGTGGT
GGTGCAGCTCGGCCTCGGCGGCGACGTGGCGATCCCGCAGAACGTGGTGGTGGCCAAGGAGCTGACGATCTGCGGCTCGT
TCCGCTTCCATGCCGAGTTCGCGCTGGCCGTGCAACTGATCAACGAGGGGCGCGTGGATCTGGCGCCGGCCATCACGCGC
GTGTTCCCGGCGCGCGAGGCGGGCGACGCGTTCGCGCTGGCGGGCGACCGGCGCCGCGCGATGAAGGTGCTGATCGATTT
CCAGGACGCGCCGGCCGATGCCGGCGCCTGA

Upstream 100 bases:

>100_bases
CCAGACGCTGTTCGTCGACGGCGGCCTGACGAGCGTGGTCTGAGCGCCGCGCGTTCCGGCATGGCTGCGTTCCCGCATTG
AGAATCAGGAGGAAACATCC

Downstream 100 bases:

>100_bases
TGCCTGCAGCGTGCGGCGGCCCGGCCCCTGACAGCGACGGCGGGGCCGCGGCGGGCGCCTCGGTCGTGCGCTGCGGCAGA
GGAAGCCGTCTAGTTTTCCT

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MRLRCMCLVIHAPNDLRYEPAEVEAPGPGQVRVQVAMGGICGSDLHYFRHGGFGAIRLQQPMILGHEVAGTVVETGEGVS
GVRVGERVAVNPSRPCGACRYCLEGLPNQCLDMRFYGSAMRMPHIQGAFRGVLVCDAAQCAKLADQVPFSIAALAEPFAV
GLHAVSRAGALLGRRVLVSGCGPIGALVAAAARVHGAREVVATDVVDEPLAVAKALGADRAINVAADPDWTKSFAADKGS
FDVVIECSGSERALRDGLEVLRPRGVVVQLGLGGDVAIPQNVVVAKELTICGSFRFHAEFALAVQLINEGRVDLAPAITR
VFPAREAGDAFALAGDRRRAMKVLIDFQDAPADAGA

Sequences:

>Translated_356_residues
MRLRCMCLVIHAPNDLRYEPAEVEAPGPGQVRVQVAMGGICGSDLHYFRHGGFGAIRLQQPMILGHEVAGTVVETGEGVS
GVRVGERVAVNPSRPCGACRYCLEGLPNQCLDMRFYGSAMRMPHIQGAFRGVLVCDAAQCAKLADQVPFSIAALAEPFAV
GLHAVSRAGALLGRRVLVSGCGPIGALVAAAARVHGAREVVATDVVDEPLAVAKALGADRAINVAADPDWTKSFAADKGS
FDVVIECSGSERALRDGLEVLRPRGVVVQLGLGGDVAIPQNVVVAKELTICGSFRFHAEFALAVQLINEGRVDLAPAITR
VFPAREAGDAFALAGDRRRAMKVLIDFQDAPADAGA
>Mature_356_residues
MRLRCMCLVIHAPNDLRYEPAEVEAPGPGQVRVQVAMGGICGSDLHYFRHGGFGAIRLQQPMILGHEVAGTVVETGEGVS
GVRVGERVAVNPSRPCGACRYCLEGLPNQCLDMRFYGSAMRMPHIQGAFRGVLVCDAAQCAKLADQVPFSIAALAEPFAV
GLHAVSRAGALLGRRVLVSGCGPIGALVAAAARVHGAREVVATDVVDEPLAVAKALGADRAINVAADPDWTKSFAADKGS
FDVVIECSGSERALRDGLEVLRPRGVVVQLGLGGDVAIPQNVVVAKELTICGSFRFHAEFALAVQLINEGRVDLAPAITR
VFPAREAGDAFALAGDRRRAMKVLIDFQDAPADAGA

Specific function: Catalyzes the NADH/NADPH-dependent oxidation of L- idonate to 5-ketogluconate (5KG) [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=352, Percent_Identity=33.5227272727273, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI4501933, Length=226, Percent_Identity=31.4159292035398, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI71565152, Length=361, Percent_Identity=23.5457063711911, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4501929, Length=226, Percent_Identity=30.5309734513274, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4501939, Length=239, Percent_Identity=28.0334728033473, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI156523966, Length=239, Percent_Identity=28.0334728033473, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI34577061, Length=223, Percent_Identity=30.4932735426009, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI71565154, Length=268, Percent_Identity=27.6119402985075, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI71743840, Length=222, Percent_Identity=26.5765765765766, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI262073058, Length=222, Percent_Identity=26.5765765765766, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1790718, Length=316, Percent_Identity=42.4050632911392, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI1788073, Length=346, Percent_Identity=32.9479768786127, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1787863, Length=346, Percent_Identity=30.9248554913295, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790045, Length=311, Percent_Identity=33.4405144694534, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788407, Length=317, Percent_Identity=29.9684542586751, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI226510992, Length=344, Percent_Identity=30.8139534883721, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788075, Length=354, Percent_Identity=28.2485875706215, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082125, Length=355, Percent_Identity=28.4507042253521, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786552, Length=354, Percent_Identity=26.5536723163842, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786518, Length=265, Percent_Identity=28.3018867924528, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081918, Length=261, Percent_Identity=27.9693486590038, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=328, Percent_Identity=39.3292682926829, Blast_Score=224, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI17562878, Length=330, Percent_Identity=38.7878787878788, Blast_Score=208, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI25146526, Length=290, Percent_Identity=27.2413793103448, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71997431, Length=292, Percent_Identity=27.3972602739726, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562584, Length=342, Percent_Identity=25.7309941520468, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565904, Length=228, Percent_Identity=27.6315789473684, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562582, Length=303, Percent_Identity=25.4125412541254, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=320, Percent_Identity=34.6875, Blast_Score=180, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6322619, Length=320, Percent_Identity=34.6875, Blast_Score=180, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6323099, Length=311, Percent_Identity=34.7266881028939, Blast_Score=179, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6319257, Length=318, Percent_Identity=28.9308176100629, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6319258, Length=341, Percent_Identity=25.8064516129032, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319621, Length=286, Percent_Identity=31.1188811188811, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323729, Length=291, Percent_Identity=30.2405498281787, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320033, Length=365, Percent_Identity=23.2876712328767, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324486, Length=287, Percent_Identity=26.8292682926829, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323961, Length=296, Percent_Identity=26.6891891891892, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319949, Length=250, Percent_Identity=28, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737897, Length=356, Percent_Identity=36.2359550561798, Blast_Score=191, Evalue=7e-49,
Organism=Drosophila melanogaster, GI17137530, Length=349, Percent_Identity=34.6704871060172, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI221457811, Length=334, Percent_Identity=25.1497005988024, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45550770, Length=334, Percent_Identity=25.1497005988024, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45551930, Length=334, Percent_Identity=25.1497005988024, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17737895, Length=291, Percent_Identity=26.1168384879725, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.264 [H]

Molecular weight: Translated: 37379; Mature: 37379

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRCMCLVIHAPNDLRYEPAEVEAPGPGQVRVQVAMGGICGSDLHYFRHGGFGAIRLQQ
CCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHCCCEEEEEECC
PMILGHEVAGTVVETGEGVSGVRVGERVAVNPSRPCGACRYCLEGLPNQCLDMRFYGSAM
CEEECHHHHCEEEECCCCCCCEECCCEEEECCCCCHHHHHHHHHCCCHHHHCEEECCCHH
RMPHIQGAFRGVLVCDAAQCAKLADQVPFSIAALAEPFAVGLHAVSRAGALLGRRVLVSG
CCCCHHHHHCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
CGPIGALVAAAARVHGAREVVATDVVDEPLAVAKALGADRAINVAADPDWTKSFAADKGS
CCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCC
FDVVIECSGSERALRDGLEVLRPRGVVVQLGLGGDVAIPQNVVVAKELTICGSFRFHAEF
EEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEEEEEECEEEHHHH
ALAVQLINEGRVDLAPAITRVFPAREAGDAFALAGDRRRAMKVLIDFQDAPADAGA
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEECCCHHHEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MRLRCMCLVIHAPNDLRYEPAEVEAPGPGQVRVQVAMGGICGSDLHYFRHGGFGAIRLQQ
CCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHCCCEEEEEECC
PMILGHEVAGTVVETGEGVSGVRVGERVAVNPSRPCGACRYCLEGLPNQCLDMRFYGSAM
CEEECHHHHCEEEECCCCCCCEECCCEEEECCCCCHHHHHHHHHCCCHHHHCEEECCCHH
RMPHIQGAFRGVLVCDAAQCAKLADQVPFSIAALAEPFAVGLHAVSRAGALLGRRVLVSG
CCCCHHHHHCEEEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
CGPIGALVAAAARVHGAREVVATDVVDEPLAVAKALGADRAINVAADPDWTKSFAADKGS
CCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCC
FDVVIECSGSERALRDGLEVLRPRGVVVQLGLGGDVAIPQNVVVAKELTICGSFRFHAEF
EEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEEEEEECEEEHHHH
ALAVQLINEGRVDLAPAITRVFPAREAGDAFALAGDRRRAMKVLIDFQDAPADAGA
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEECCCHHHEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]