Click here to switch to the map view.

The map label for this gene is gph [H]

Identifier: 238024298

GI number: 238024298

Start: 1071260

End: 1071922

Strand: Reverse

Name: gph [H]

Synonym: bglu_2g08840

Alternate gene names: 238024298

Gene position: 1071922-1071260 (Counterclockwise)

Preceding gene: 238024299

Following gene: 238024297

Centisome position: 37.91

GC content: 70.89

Gene sequence:

>663_bases
GTGAGCGACATCACGTTCCTGTTCGACCTCGACGGTACGCTCGTCGATACCGACGCCCTGCACCTGAACGCCTACAACAC
GCTGCTCGCGCGCTGGCAGCGCGCGATCGATCTCGACTACTACAAGACGCACGTGATGGGCTTTCCCGACCACATGATCT
TCGGCGGCCTGTTTCCCGGCATGCCGGCGGCCGAGTTCACGGCGCTGGCGGCCGAGAAGGAGCAACTGTTTCGCGATCAG
CTCGGCGCGCGCCTCACGCCGACGGCCGGCACCGAGGCGCTGCTGCGCCGCATCGAGCGCGCCGGCGCGCGCAGCGCCGT
GGTCACCAACGCGCCGCGCGAGAATGCCCGGATGATGCTGGAGGCGCTCGGTCTCGCCGCCCGCTTCGAGACGCTCGTGA
TCGGCGGCGAACTCGCGCACGGCAAGCCGCATCCGCTGCCCTACCTCACCGCGCTCGAGGCGCTCGGCGGCGATGCCGCG
CGCGCGGTGGCGTTCGAGGATTCGGCCTCGGGCGTGCGCTCGGCCAGCGCGGCCGGCATCCATACCTTCGGCATGCGCAC
CGCGCTCGGCGACACGCAGTTGCGCGAGGCCGGCGCGCACCAGACGATCCGCGATTTCGAGGACCCCGCGCTCGCGCAGT
GGCTGGCGCACCTGGGCGTTTGA

Upstream 100 bases:

>100_bases
TGGTGGCGTGCCCGCTCCTGATGCTGCCGTTCCTGCCCGGGCTGCGCGAGCCAAGACCGCGCACCGCCCATTACCAAGCC
TCAGAAGGAGTCTCCCCGAA

Downstream 100 bases:

>100_bases
ACCGCGCTGAACCGCGCTGAACCGCGCGCCGTGGGCGCGCGGGGGCGACGGCCGGACTTGTCCGGATCTTTCCGGCCTCG
GAAGACAACCGTGACGATCC

Product: HAD-superfamily hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MSDITFLFDLDGTLVDTDALHLNAYNTLLARWQRAIDLDYYKTHVMGFPDHMIFGGLFPGMPAAEFTALAAEKEQLFRDQ
LGARLTPTAGTEALLRRIERAGARSAVVTNAPRENARMMLEALGLAARFETLVIGGELAHGKPHPLPYLTALEALGGDAA
RAVAFEDSASGVRSASAAGIHTFGMRTALGDTQLREAGAHQTIRDFEDPALAQWLAHLGV

Sequences:

>Translated_220_residues
MSDITFLFDLDGTLVDTDALHLNAYNTLLARWQRAIDLDYYKTHVMGFPDHMIFGGLFPGMPAAEFTALAAEKEQLFRDQ
LGARLTPTAGTEALLRRIERAGARSAVVTNAPRENARMMLEALGLAARFETLVIGGELAHGKPHPLPYLTALEALGGDAA
RAVAFEDSASGVRSASAAGIHTFGMRTALGDTQLREAGAHQTIRDFEDPALAQWLAHLGV
>Mature_219_residues
SDITFLFDLDGTLVDTDALHLNAYNTLLARWQRAIDLDYYKTHVMGFPDHMIFGGLFPGMPAAEFTALAAEKEQLFRDQL
GARLTPTAGTEALLRRIERAGARSAVVTNAPRENARMMLEALGLAARFETLVIGGELAHGKPHPLPYLTALEALGGDAAR
AVAFEDSASGVRSASAAGIHTFGMRTALGDTQLREAGAHQTIRDFEDPALAQWLAHLGV

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23728; Mature: 23597

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDITFLFDLDGTLVDTDALHLNAYNTLLARWQRAIDLDYYKTHVMGFPDHMIFGGLFPG
CCCEEEEEECCCCEEECCCEEHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHCCCCCC
MPAAEFTALAAEKEQLFRDQLGARLTPTAGTEALLRRIERAGARSAVVTNAPRENARMML
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHH
EALGLAARFETLVIGGELAHGKPHPLPYLTALEALGGDAARAVAFEDSASGVRSASAAGI
HHHHHHHHHHHEEECCEECCCCCCCCHHHHHHHHHCCCHHHEEEECCCCCHHHHHCCCCH
HTFGMRTALGDTQLREAGAHQTIRDFEDPALAQWLAHLGV
HHHHHHHHCCHHHHHHHCCHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SDITFLFDLDGTLVDTDALHLNAYNTLLARWQRAIDLDYYKTHVMGFPDHMIFGGLFPG
CCEEEEEECCCCEEECCCEEHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHCCCCCC
MPAAEFTALAAEKEQLFRDQLGARLTPTAGTEALLRRIERAGARSAVVTNAPRENARMML
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHH
EALGLAARFETLVIGGELAHGKPHPLPYLTALEALGGDAARAVAFEDSASGVRSASAAGI
HHHHHHHHHHHEEECCEECCCCCCCCHHHHHHHHHCCCHHHEEEECCCCCHHHHHCCCCH
HTFGMRTALGDTQLREAGAHQTIRDFEDPALAQWLAHLGV
HHHHHHHHCCHHHHHHHCCHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]