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The map label for this gene is trpA [H]

Identifier: 238024261

GI number: 238024261

Start: 1023041

End: 1023853

Strand: Direct

Name: trpA [H]

Synonym: bglu_2g08440

Alternate gene names: 238024261

Gene position: 1023041-1023853 (Clockwise)

Preceding gene: 238024260

Following gene: 238024262

Centisome position: 36.18

GC content: 71.22

Gene sequence:

>813_bases
ATGTCCCGAATCCAGAATACCTTCGCAGCACTGGCCGCCCAGGGCCGTAAAGGGCTGATCCCGTTCATCACGGCGGGCGA
CCCGGACCCGGCGAAGACCGTCGATTTCATGCATGCGCTCGCGGCGGGCGGCGCCGACGTGATCGAGCTCGGCGTGCCGT
TCTCGGACCCGATGGCCGACGGCCCGGTGATCCAGCGCTCCTCCGAGCGCGCGCTGGCGCGCGGCGTCACGCTGCGGCAC
GTGCTCGACGACGTCAGGCGCTTTCGCGAGCGCGACGACCGCACCCCCGTGGTGCTGATGGGCTATGCCAACCCGATCGA
GCGGATGGGCACCGAGGCCTTCGCCGCCGCGGCCAGCGCGGCCGGCGTCGACGGCGTGCTGGTGGTGGACTATCCGCCCG
AGGAGGCGGCCGGGTTCGCCGCCACGATGCGGGCCGCCGGGGTCGACCCGATTTTCCTGCTCGCGCCGACCTCGACCGAG
CAACGGATGGCCGAAGTGGGCCGGATCGCGAGCGGATATGTTTATTATGTGTCGCTGAAGGGGGTGACCGGCGCCGGAAA
TCTGGATGTTTCCAGCATTGCGGGTAAAATCCCGGCCATCAAGTCGCGCGTGCCGGTTCCGGTCGGCGTCGGCTTCGGGA
TCCGCGACGCCGCCACCGCGCGCGCCGTGGCCGAGGTTGCCGATGCCGTGGTGATCGGCAGCCGCCTCGTGCAACTGCTC
GAGGAGTCGGCGCCGGAGGCGGCCGCAGGCGCGCTGCAGGCGTTCGTCGCCGGCATCCGCGCCGCGCTCGACGGCGAGGC
GAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGAACGCGTGGCCGCGCTCGCCGCGCCGGCGGATGCGTGAGGCGGGCCGGATGCCCGCCTGAGCGCCGCCCATCGTCATC
GAATCAAGGAAAGCCACACC

Downstream 100 bases:

>100_bases
CGGCCGCCGGTTGCCGTCGCTGCCCCGCACGCGCACCGTCCAGAAACACCGAACGCGGGCCGCCACCGGCCCGCCATGAA
GAAGGAAACCAAACGATGAG

Product: tryptophan synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVDFMHALAAGGADVIELGVPFSDPMADGPVIQRSSERALARGVTLRH
VLDDVRRFRERDDRTPVVLMGYANPIERMGTEAFAAAASAAGVDGVLVVDYPPEEAAGFAATMRAAGVDPIFLLAPTSTE
QRMAEVGRIASGYVYYVSLKGVTGAGNLDVSSIAGKIPAIKSRVPVPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLL
EESAPEAAAGALQAFVAGIRAALDGEAKAA

Sequences:

>Translated_270_residues
MSRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVDFMHALAAGGADVIELGVPFSDPMADGPVIQRSSERALARGVTLRH
VLDDVRRFRERDDRTPVVLMGYANPIERMGTEAFAAAASAAGVDGVLVVDYPPEEAAGFAATMRAAGVDPIFLLAPTSTE
QRMAEVGRIASGYVYYVSLKGVTGAGNLDVSSIAGKIPAIKSRVPVPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLL
EESAPEAAAGALQAFVAGIRAALDGEAKAA
>Mature_269_residues
SRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVDFMHALAAGGADVIELGVPFSDPMADGPVIQRSSERALARGVTLRHV
LDDVRRFRERDDRTPVVLMGYANPIERMGTEAFAAAASAAGVDGVLVVDYPPEEAAGFAATMRAAGVDPIFLLAPTSTEQ
RMAEVGRIASGYVYYVSLKGVTGAGNLDVSSIAGKIPAIKSRVPVPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLLE
ESAPEAAAGALQAFVAGIRAALDGEAKAA

Specific function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate [H]

COG id: COG0159

COG function: function code E; Tryptophan synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpA family [H]

Homologues:

Organism=Escherichia coli, GI1787514, Length=265, Percent_Identity=34.7169811320755, Blast_Score=150, Evalue=6e-38,
Organism=Saccharomyces cerevisiae, GI6321412, Length=262, Percent_Identity=39.3129770992366, Blast_Score=179, Evalue=6e-46,

Paralogues:

None

Copy number: 280 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR018204
- InterPro:   IPR002028 [H]

Pfam domain/function: PF00290 Trp_syntA [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 27797; Mature: 27666

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00167 TRP_SYNTHASE_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVDFMHALAAGGADVIELGVPFSDPMAD
CCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
GPVIQRSSERALARGVTLRHVLDDVRRFRERDDRTPVVLMGYANPIERMGTEAFAAAASA
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCHHHHHHHHHH
AGVDGVLVVDYPPEEAAGFAATMRAAGVDPIFLLAPTSTEQRMAEVGRIASGYVYYVSLK
CCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEEEE
GVTGAGNLDVSSIAGKIPAIKSRVPVPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLL
CCCCCCCCCHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EESAPEAAAGALQAFVAGIRAALDGEAKAA
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SRIQNTFAALAAQGRKGLIPFITAGDPDPAKTVDFMHALAAGGADVIELGVPFSDPMAD
CHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCC
GPVIQRSSERALARGVTLRHVLDDVRRFRERDDRTPVVLMGYANPIERMGTEAFAAAASA
CCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCHHHHHHHHHH
AGVDGVLVVDYPPEEAAGFAATMRAAGVDPIFLLAPTSTEQRMAEVGRIASGYVYYVSLK
CCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEEEE
GVTGAGNLDVSSIAGKIPAIKSRVPVPVGVGFGIRDAATARAVAEVADAVVIGSRLVQLL
CCCCCCCCCHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EESAPEAAAGALQAFVAGIRAALDGEAKAA
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA