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The map label for this gene is gltA [H]

Identifier: 238024246

GI number: 238024246

Start: 1006040

End: 1007344

Strand: Direct

Name: gltA [H]

Synonym: bglu_2g08280

Alternate gene names: 238024246

Gene position: 1006040-1007344 (Clockwise)

Preceding gene: 238024245

Following gene: 238024247

Centisome position: 35.58

GC content: 62.38

Gene sequence:

>1305_bases
ATGACTCCGTCTGATGTTAAAGCCACGCTATCGTTCAGCGACAATTCGCCGAGCGTCGAACTGCCGATCTACAAGGGCAC
GATGGGCCCGGACGTGATCGACATCCGCAAGCTGTACGGCCAGACCGGCAAGTTCACGTACGACCCGGGCTTCATGTCCA
CGGCCTCGTGCAACTCGCAGATCACGTACATTGACGGGGACAAGGGCGAACTGCTGTATCGCGGTTACCCCATCGACAAC
CTCGCGCAAAACGCGGACTTCCTCGAAACGTGCTACCTGCTGCTGAAGGGCGAGCTGCCGAACGCCGCCCAGAAGGCGGA
ATTCGTCGATACCGTCACGAAGCACACGATGGTGCACGAGCAGATGCACTTCTTCTTCCGCGGCTTCCGTCGCGACGCGC
ATCCGATGGCGATCCTGGTCGCCGCGGTGGGCGCGCTGTCGGCGTTCTACCACGACTCGCTCGACATCAACGACCCGCGC
CACCGTGAAGTCTCGGCGATCCGCATGATCGCCAAGCTGCCGACGCTGGTCGCGATGGCCTACAAGTACAGCATCGGCCA
GCCGTTCGTCTATCCGAAGAACGAGCTGTCGTACAGCGCGAACTTCATGCACATGATGTTCTCGAACCCGTGCGAGGAGT
ACAAGGTCAACGACGTGCTGGTGCGCGCGCTCGACCGCATCCTGATCCTGCACGCCGACCACGAGCAGAACGCCTCGACC
TCGACGGTGCGTCTGGCCGGTTCGTCGGGTGCGAACCCGTTCGCCTGCATCGCGGCCGGGATCGCTTGCCTCTGGGGCCC
GGCTCACGGCGGCGCGAACGAAGCCGCGCTGAACATGCTCGAGCAGATCGGCTCGTCGGACAACATCCCCGAATTCATCA
AGCAGGTGAAGGACAAGAACTCGGGCGTGAAGCTGATGGGCTTCGGCCACCGCGTGTACAAGAACTACGATCCGCGTGCG
AAGCTGATGCGCGAAACCTGCCACGAAGTGCTCGAAGAGCTCGGCCTGCACGACGATCCGCTGTTCAAGCTCGCGATGCA
GCTCGAGAAGATCGCCCTCGAGGACGAATACTTCGTGTCGCGCAAGCTGTACCCGAACGTCGATTTCTACTCGGGCATCG
TCCAGCGCGCGCTGGGCATCCCGACCTCGATGTTCACCTGCATCTTCTCGATGGCGCGTACCGTCGGCTGGATCGGCCAA
TGGAACGAGATGATCGCCGATCCCGAGCAGAAGATCGGCCGTCCGCGCCAGCTGTTCGTCGGCCAGACGCCGCGCGAAGC
GGTGCCGATCGCGCAGCGTTCCTAA

Upstream 100 bases:

>100_bases
CCGGCCCGGACGTTTCCCGGCTGCTGGAGATGCTGCGCAGTGCATGAGAGCGCTGCGTCCGTTATCGAATTCCGTTTTCA
TTTTCGATTGAGGATGTGCC

Downstream 100 bases:

>100_bases
TCGCGTCCGGCCGTCTCCGAACGGCCGCGCGCCGCGCATGAGAAACACCCCGGCGGCTTCGGCCGCCGGGGTGTTTTGCT
TGGTAAGGGCGCGCTCGGGC

Product: type II citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTPSDVKATLSFSDNSPSVELPIYKGTMGPDVIDIRKLYGQTGKFTYDPGFMSTASCNSQITYIDGDKGELLYRGYPIDN
LAQNADFLETCYLLLKGELPNAAQKAEFVDTVTKHTMVHEQMHFFFRGFRRDAHPMAILVAAVGALSAFYHDSLDINDPR
HREVSAIRMIAKLPTLVAMAYKYSIGQPFVYPKNELSYSANFMHMMFSNPCEEYKVNDVLVRALDRILILHADHEQNAST
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLEQIGSSDNIPEFIKQVKDKNSGVKLMGFGHRVYKNYDPRA
KLMRETCHEVLEELGLHDDPLFKLAMQLEKIALEDEYFVSRKLYPNVDFYSGIVQRALGIPTSMFTCIFSMARTVGWIGQ
WNEMIADPEQKIGRPRQLFVGQTPREAVPIAQRS

Sequences:

>Translated_434_residues
MTPSDVKATLSFSDNSPSVELPIYKGTMGPDVIDIRKLYGQTGKFTYDPGFMSTASCNSQITYIDGDKGELLYRGYPIDN
LAQNADFLETCYLLLKGELPNAAQKAEFVDTVTKHTMVHEQMHFFFRGFRRDAHPMAILVAAVGALSAFYHDSLDINDPR
HREVSAIRMIAKLPTLVAMAYKYSIGQPFVYPKNELSYSANFMHMMFSNPCEEYKVNDVLVRALDRILILHADHEQNAST
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLEQIGSSDNIPEFIKQVKDKNSGVKLMGFGHRVYKNYDPRA
KLMRETCHEVLEELGLHDDPLFKLAMQLEKIALEDEYFVSRKLYPNVDFYSGIVQRALGIPTSMFTCIFSMARTVGWIGQ
WNEMIADPEQKIGRPRQLFVGQTPREAVPIAQRS
>Mature_433_residues
TPSDVKATLSFSDNSPSVELPIYKGTMGPDVIDIRKLYGQTGKFTYDPGFMSTASCNSQITYIDGDKGELLYRGYPIDNL
AQNADFLETCYLLLKGELPNAAQKAEFVDTVTKHTMVHEQMHFFFRGFRRDAHPMAILVAAVGALSAFYHDSLDINDPRH
REVSAIRMIAKLPTLVAMAYKYSIGQPFVYPKNELSYSANFMHMMFSNPCEEYKVNDVLVRALDRILILHADHEQNASTS
TVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLEQIGSSDNIPEFIKQVKDKNSGVKLMGFGHRVYKNYDPRAK
LMRETCHEVLEELGLHDDPLFKLAMQLEKIALEDEYFVSRKLYPNVDFYSGIVQRALGIPTSMFTCIFSMARTVGWIGQW
NEMIADPEQKIGRPRQLFVGQTPREAVPIAQRS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=423, Percent_Identity=27.8959810874704, Blast_Score=114, Evalue=3e-25,
Organism=Escherichia coli, GI1786939, Length=423, Percent_Identity=66.4302600472813, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI1786527, Length=384, Percent_Identity=28.3854166666667, Blast_Score=155, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI17555174, Length=411, Percent_Identity=27.007299270073, Blast_Score=114, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6319850, Length=329, Percent_Identity=27.355623100304, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324328, Length=340, Percent_Identity=26.4705882352941, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6325257, Length=366, Percent_Identity=25.4098360655738, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640126, Length=424, Percent_Identity=26.6509433962264, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24640124, Length=424, Percent_Identity=26.6509433962264, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21356863, Length=425, Percent_Identity=26.3529411764706, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 48549; Mature: 48418

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSDVKATLSFSDNSPSVELPIYKGTMGPDVIDIRKLYGQTGKFTYDPGFMSTASCNSQ
CCCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEECCCCCEECCCCCE
ITYIDGDKGELLYRGYPIDNLAQNADFLETCYLLLKGELPNAAQKAEFVDTVTKHTMVHE
EEEEECCCCCEEEECCCHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
QMHFFFRGFRRDAHPMAILVAAVGALSAFYHDSLDINDPRHREVSAIRMIAKLPTLVAMA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YKYSIGQPFVYPKNELSYSANFMHMMFSNPCEEYKVNDVLVRALDRILILHADHEQNAST
HHHHCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCC
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLEQIGSSDNIPEFIKQVKDKN
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCC
SGVKLMGFGHRVYKNYDPRAKLMRETCHEVLEELGLHDDPLFKLAMQLEKIALEDEYFVS
CCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHH
RKLYPNVDFYSGIVQRALGIPTSMFTCIFSMARTVGWIGQWNEMIADPEQKIGRPRQLFV
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEC
GQTPREAVPIAQRS
CCCCHHHCCCCCCC
>Mature Secondary Structure 
TPSDVKATLSFSDNSPSVELPIYKGTMGPDVIDIRKLYGQTGKFTYDPGFMSTASCNSQ
CCCCCEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEECCCCCEECCCCCE
ITYIDGDKGELLYRGYPIDNLAQNADFLETCYLLLKGELPNAAQKAEFVDTVTKHTMVHE
EEEEECCCCCEEEECCCHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
QMHFFFRGFRRDAHPMAILVAAVGALSAFYHDSLDINDPRHREVSAIRMIAKLPTLVAMA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YKYSIGQPFVYPKNELSYSANFMHMMFSNPCEEYKVNDVLVRALDRILILHADHEQNAST
HHHHCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCC
STVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLEQIGSSDNIPEFIKQVKDKN
CEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCC
SGVKLMGFGHRVYKNYDPRAKLMRETCHEVLEELGLHDDPLFKLAMQLEKIALEDEYFVS
CCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHH
RKLYPNVDFYSGIVQRALGIPTSMFTCIFSMARTVGWIGQWNEMIADPEQKIGRPRQLFV
CCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEC
GQTPREAVPIAQRS
CCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]