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The map label for this gene is mcl1 [H]

Identifier: 238024238

GI number: 238024238

Start: 998922

End: 999944

Strand: Reverse

Name: mcl1 [H]

Synonym: bglu_2g08200

Alternate gene names: 238024238

Gene position: 999944-998922 (Counterclockwise)

Preceding gene: 238024239

Following gene: 238024237

Centisome position: 35.37

GC content: 73.41

Gene sequence:

>1023_bases
ATGCCCGCGCTCTCTCCTGCTGAAGTGCTGTACGACGGCGCCGCGCCCCCCGCGCTCCTGCCCTGCTGCGATCACTACGC
CGGCAGCGAGAAACTGATGCGCAAGTCGCTGGCGCTGCAGGCCGAACTGGGCCCGGTGTTCGACGTGACGCTCGACTGCG
AGGACGGCGCCGCCGTCGGCCGCGAGGCCGCGCACGCCGAACTGGTGGCCGCGATGCTCGGCGACGCGGCCAACCGCTTC
GGCCGTGCCGGCGTGCGGATCCACGACTTCTCCCACCCGCACTGGCGCGACGACCTGCGCATCGTGTTGCGCGCCGCCCG
GCCGCCTGCTTACATTACGCTTCCAAAAACCACCGACGCGGCCGACGTGGCCGAGGTCTGCGCGTTCATCGAGGGCACGC
GCCGCGAGCTCGGCATCGCCCGGCCGATCCCGGCCGACGTGCTGATCGAGACGCACGGCGCGCTCGCCCAGGTCGCTCGC
ATCGCCGCCCTGCCGGCCGTCTCGACGCTGAGCTTCGGGCTGATGGATTTCGTCTCCGCCCATCACGGCGCGATCCCCGA
CGCCGCCATGCGCGCGCCAGGCCAGTTCGACCATCCGCTGGTGCGCCGCGCCAAGCTCGAGATCGCCGCCGCCTGCCACG
CCCACGGCAAGACGCCGTCCCACAATGTGACCACCGAGATCCGCGAGATGGCCATGGTGGCGAGCGACGCCGCCCGCGCG
CGCGACGAATTCGGCTACACGCGGATGTGGAGCATCCATCCCGCGCAGATCCGCGAGATCGTGGCCGCGTTCGCGCCGCG
CGAGGCAGAAGTGGCGCTGGCCGCGGAAATCCTGCTTGCCGCGCAGGCCGCCGACTGGGGGCCGACGCGCCACCGCGACA
CGCTGCACGACCGCGCCAGCTACCGCTATTACTGGTCGGTGCTGCGCCGCGCGCACGCCGCCGGCGCCGCGCTGCCGGCC
GAGGTGGCGCGCTGGCTGCCGGCCGAGGCCGCCGGTGCGGCCGGCAGCCAGGCCTGCGCGTGA

Upstream 100 bases:

>100_bases
CCCCGCATTCGATCCGCACGCGCGTTGCCCGCGCCCGCCGCCGCAGCGCCCGTCCGAATCCGATGCCCTTTCGATCACGC
CGCCCCGACGCGTAACGACG

Downstream 100 bases:

>100_bases
AGGGTGCCGGTGCGCCCGGCCCCGCGCCGAGCGTGCCGCGTACCGGCGCCCCGGCCCGCCCGCTGGTCACGGCCTTTGCC
GCCACTATCGCGAAATCACG

Product: HpcH/HpaI aldolase

Products: NA

Alternate protein names: (3S)-malyl-CoA/beta-methylmalyl-CoA lyase; L-malyl-CoA/beta-methylmalyl-CoA lyase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MPALSPAEVLYDGAAPPALLPCCDHYAGSEKLMRKSLALQAELGPVFDVTLDCEDGAAVGREAAHAELVAAMLGDAANRF
GRAGVRIHDFSHPHWRDDLRIVLRAARPPAYITLPKTTDAADVAEVCAFIEGTRRELGIARPIPADVLIETHGALAQVAR
IAALPAVSTLSFGLMDFVSAHHGAIPDAAMRAPGQFDHPLVRRAKLEIAAACHAHGKTPSHNVTTEIREMAMVASDAARA
RDEFGYTRMWSIHPAQIREIVAAFAPREAEVALAAEILLAAQAADWGPTRHRDTLHDRASYRYYWSVLRRAHAAGAALPA
EVARWLPAEAAGAAGSQACA

Sequences:

>Translated_340_residues
MPALSPAEVLYDGAAPPALLPCCDHYAGSEKLMRKSLALQAELGPVFDVTLDCEDGAAVGREAAHAELVAAMLGDAANRF
GRAGVRIHDFSHPHWRDDLRIVLRAARPPAYITLPKTTDAADVAEVCAFIEGTRRELGIARPIPADVLIETHGALAQVAR
IAALPAVSTLSFGLMDFVSAHHGAIPDAAMRAPGQFDHPLVRRAKLEIAAACHAHGKTPSHNVTTEIREMAMVASDAARA
RDEFGYTRMWSIHPAQIREIVAAFAPREAEVALAAEILLAAQAADWGPTRHRDTLHDRASYRYYWSVLRRAHAAGAALPA
EVARWLPAEAAGAAGSQACA
>Mature_339_residues
PALSPAEVLYDGAAPPALLPCCDHYAGSEKLMRKSLALQAELGPVFDVTLDCEDGAAVGREAAHAELVAAMLGDAANRFG
RAGVRIHDFSHPHWRDDLRIVLRAARPPAYITLPKTTDAADVAEVCAFIEGTRRELGIARPIPADVLIETHGALAQVARI
AALPAVSTLSFGLMDFVSAHHGAIPDAAMRAPGQFDHPLVRRAKLEIAAACHAHGKTPSHNVTTEIREMAMVASDAARAR
DEFGYTRMWSIHPAQIREIVAAFAPREAEVALAAEILLAAQAADWGPTRHRDTLHDRASYRYYWSVLRRAHAAGAALPAE
VARWLPAEAAGAAGSQACA

Specific function: Catalyzes the reversible condensation of glyoxylate and acetyl-CoA to L-malyl-CoA and the reversible condensation of glyoxylate and propionyl-CoA to beta-methylmalyl-CoA [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.24 [H]

Molecular weight: Translated: 36347; Mature: 36216

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALSPAEVLYDGAAPPALLPCCDHYAGSEKLMRKSLALQAELGPVFDVTLDCEDGAAVG
CCCCCHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
REAAHAELVAAMLGDAANRFGRAGVRIHDFSHPHWRDDLRIVLRAARPPAYITLPKTTDA
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCH
ADVAEVCAFIEGTRRELGIARPIPADVLIETHGALAQVARIAALPAVSTLSFGLMDFVSA
HHHHHHHHHHHHHHHHCCCCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HHGAIPDAAMRAPGQFDHPLVRRAKLEIAAACHAHGKTPSHNVTTEIREMAMVASDAARA
HCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
RDEFGYTRMWSIHPAQIREIVAAFAPREAEVALAAEILLAAQAADWGPTRHRDTLHDRAS
HHHCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YRYYWSVLRRAHAAGAALPAEVARWLPAEAAGAAGSQACA
HHHHHHHHHHHHHCCCCCHHHHHHHCCCHHCCCCCCCCCC
>Mature Secondary Structure 
PALSPAEVLYDGAAPPALLPCCDHYAGSEKLMRKSLALQAELGPVFDVTLDCEDGAAVG
CCCCHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHH
REAAHAELVAAMLGDAANRFGRAGVRIHDFSHPHWRDDLRIVLRAARPPAYITLPKTTDA
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCH
ADVAEVCAFIEGTRRELGIARPIPADVLIETHGALAQVARIAALPAVSTLSFGLMDFVSA
HHHHHHHHHHHHHHHHCCCCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HHGAIPDAAMRAPGQFDHPLVRRAKLEIAAACHAHGKTPSHNVTTEIREMAMVASDAARA
HCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
RDEFGYTRMWSIHPAQIREIVAAFAPREAEVALAAEILLAAQAADWGPTRHRDTLHDRAS
HHHCCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
YRYYWSVLRRAHAAGAALPAEVARWLPAEAAGAAGSQACA
HHHHHHHHHHHHHCCCCCHHHHHHHCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA