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The map label for this gene is macB [H]

Identifier: 238024205

GI number: 238024205

Start: 949011

End: 950408

Strand: Reverse

Name: macB [H]

Synonym: bglu_2g07850

Alternate gene names: 238024205

Gene position: 950408-949011 (Counterclockwise)

Preceding gene: 238024206

Following gene: 238024204

Centisome position: 33.62

GC content: 69.89

Gene sequence:

>1398_bases
ATGAGCGTCTGGGTGCTCGCCTTCCGCAACCTGTTGCGCAACCGCCGCCGCTCGTCCACCACGCTGCTGGCGATGATCGT
CGGCCTGACCGCGATCCTGCTGTTCGGCGGCTATGCGCGCAACATCAATTACGGCCTCCAGACCAGCTACGTGCGCCAGG
GCGGCCATCTGCAGATCCAGCACCGCGACTATTTCCTGTACGGCAGCGGCGACCCTGTCTCCTACGGGATCGACGACTAC
CGGAAGGTCATGGATACCGTGCGCGGCGATCCCGAGCTGGCGCGCGAGGTGACGGTGGTGACGCCGGTGCTGACCGTCAA
CGGCATCGCCGGCAACTTCGCGGCGGGCGTCTCGCGCACCGTCTCGGGCAGCGGGATCGTGGTGGCCGACCAGAACCGGA
TGCGCCAGTGGAACGACTATGGTTTCGCCGATCGCGCGACACCCCTCGCGCTGACCGGCAGCGCCGCGAATGCCGTGGTG
ATCGGCACCGGCGTCGCGCGCGTGCTGCGCCTGTGCGACGCGCTGCGGGTACCCGCATGCCGCGATCCGGTGCCGGCCGC
CCCGGCCGGCACGTCGGAACTGCCTGCCGACATCGCCTCGCTGTCGCAGGCCGAGGCCGCCGCGAAGCCCAAGCACGGCG
GCGGGCCCGCCCGCCTCGAACTGCTGACCTCGAATGCGTACGGCGCGCCGAACGTCGCCGATCTGTCGGTGATCGCGGCG
CAGAAGCAAGGCGTCAAGCAGATCGACGACATGTTCGTGCAGATGCGTCTTGCGCAGGCGCAGCAGCTCGTCTACGGCAG
CGGCCCGAGTGCGAAGGTGACGTCCATCGTCGTGCAGCTGAAGCACACGGCCGATCTGCCGGCCGCGCGCGCGCGCATCC
AGACGCTGCTGCGCACCCGGCTCGCGGGCGAGCCGCTCGAGGTGCTCGGCTTCGCGACGCTGAATCCGCAGTACGGGCAG
GTCACCGGTATGTTCGGCGCGATCTTCGGCTTCATCGCCATCTTGATCGCCACGATCGTGCTGTTCACGGTCGGCAACAC
GATGAACATGGCCGTGATGGAGCGCACCCACGAGATCGGCACGCTGCGCGCACTCGGTCTGCGCGACGCCGGCATTCGCC
GGCTGTTCGTCTGCGAAGGGTGCCTGCTCGGCATCTGCGGCGCCGCCGCGGGCACCGTGCTCGCACTCGCGGCGGGAGTC
GCGATCAACCGCGCCGGCCTGCACTGGACGCCGCCCGGGCAGACCGATCCGGTCGCCCTGTCGGTACGCGTATGGGGCGA
GTTCGGGATGATCGCGCGCTACGCACTCGGCGTGACGGTGGTGGCGACGCTCTCGGCCTGGCTGCCCGCGCACCGTGCCG
CCCGCCTGCCGATCGTCGAGGCCTTGCGCTTCGCCTGA

Upstream 100 bases:

>100_bases
ACGACCCGCAGGTGATCGCGGCCGCGGACGATGTCGCGACGATCAGCGACGGGCGCGTCGTCGCGACCCGCCCGACCGCG
CTGCACGAGGAGGCCTGCCA

Downstream 100 bases:

>100_bases
CCTGGAGCCTTCAACATGACATTCCCGATCCGGATCATGCGCGCCGCCGCGCTGCTGCTCGCGCTCGCCGCCAGCGCGGC
CGCGGCGAGCGGCCCGTCGG

Product: efflux ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSVWVLAFRNLLRNRRRSSTTLLAMIVGLTAILLFGGYARNINYGLQTSYVRQGGHLQIQHRDYFLYGSGDPVSYGIDDY
RKVMDTVRGDPELAREVTVVTPVLTVNGIAGNFAAGVSRTVSGSGIVVADQNRMRQWNDYGFADRATPLALTGSAANAVV
IGTGVARVLRLCDALRVPACRDPVPAAPAGTSELPADIASLSQAEAAAKPKHGGGPARLELLTSNAYGAPNVADLSVIAA
QKQGVKQIDDMFVQMRLAQAQQLVYGSGPSAKVTSIVVQLKHTADLPAARARIQTLLRTRLAGEPLEVLGFATLNPQYGQ
VTGMFGAIFGFIAILIATIVLFTVGNTMNMAVMERTHEIGTLRALGLRDAGIRRLFVCEGCLLGICGAAAGTVLALAAGV
AINRAGLHWTPPGQTDPVALSVRVWGEFGMIARYALGVTVVATLSAWLPAHRAARLPIVEALRFA

Sequences:

>Translated_465_residues
MSVWVLAFRNLLRNRRRSSTTLLAMIVGLTAILLFGGYARNINYGLQTSYVRQGGHLQIQHRDYFLYGSGDPVSYGIDDY
RKVMDTVRGDPELAREVTVVTPVLTVNGIAGNFAAGVSRTVSGSGIVVADQNRMRQWNDYGFADRATPLALTGSAANAVV
IGTGVARVLRLCDALRVPACRDPVPAAPAGTSELPADIASLSQAEAAAKPKHGGGPARLELLTSNAYGAPNVADLSVIAA
QKQGVKQIDDMFVQMRLAQAQQLVYGSGPSAKVTSIVVQLKHTADLPAARARIQTLLRTRLAGEPLEVLGFATLNPQYGQ
VTGMFGAIFGFIAILIATIVLFTVGNTMNMAVMERTHEIGTLRALGLRDAGIRRLFVCEGCLLGICGAAAGTVLALAAGV
AINRAGLHWTPPGQTDPVALSVRVWGEFGMIARYALGVTVVATLSAWLPAHRAARLPIVEALRFA
>Mature_464_residues
SVWVLAFRNLLRNRRRSSTTLLAMIVGLTAILLFGGYARNINYGLQTSYVRQGGHLQIQHRDYFLYGSGDPVSYGIDDYR
KVMDTVRGDPELAREVTVVTPVLTVNGIAGNFAAGVSRTVSGSGIVVADQNRMRQWNDYGFADRATPLALTGSAANAVVI
GTGVARVLRLCDALRVPACRDPVPAAPAGTSELPADIASLSQAEAAAKPKHGGGPARLELLTSNAYGAPNVADLSVIAAQ
KQGVKQIDDMFVQMRLAQAQQLVYGSGPSAKVTSIVVQLKHTADLPAARARIQTLLRTRLAGEPLEVLGFATLNPQYGQV
TGMFGAIFGFIAILIATIVLFTVGNTMNMAVMERTHEIGTLRALGLRDAGIRRLFVCEGCLLGICGAAAGTVLALAAGVA
INRAGLHWTPPGQTDPVALSVRVWGEFGMIARYALGVTVVATLSAWLPAHRAARLPIVEALRFA

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 49309; Mature: 49178

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVWVLAFRNLLRNRRRSSTTLLAMIVGLTAILLFGGYARNINYGLQTSYVRQGGHLQIQ
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHCCCCCEEEE
HRDYFLYGSGDPVSYGIDDYRKVMDTVRGDPELAREVTVVTPVLTVNGIAGNFAAGVSRT
ECEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHEEEEEEEEEEECCCCCCHHHCCHHE
VSGSGIVVADQNRMRQWNDYGFADRATPLALTGSAANAVVIGTGVARVLRLCDALRVPAC
ECCCEEEEECCHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHCCCCC
RDPVPAAPAGTSELPADIASLSQAEAAAKPKHGGGPARLELLTSNAYGAPNVADLSVIAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHH
QKQGVKQIDDMFVQMRLAQAQQLVYGSGPSAKVTSIVVQLKHTADLPAARARIQTLLRTR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEHHHCCCCHHHHHHHHHHHHHH
LAGEPLEVLGFATLNPQYGQVTGMFGAIFGFIAILIATIVLFTVGNTMNMAVMERTHEIG
HCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TLRALGLRDAGIRRLFVCEGCLLGICGAAAGTVLALAAGVAINRAGLHWTPPGQTDPVAL
HEHEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCCCCCCEEE
SVRVWGEFGMIARYALGVTVVATLSAWLPAHRAARLPIVEALRFA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure 
SVWVLAFRNLLRNRRRSSTTLLAMIVGLTAILLFGGYARNINYGLQTSYVRQGGHLQIQ
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHCCCCCEEEE
HRDYFLYGSGDPVSYGIDDYRKVMDTVRGDPELAREVTVVTPVLTVNGIAGNFAAGVSRT
ECEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHEEEEEEEEEEECCCCCCHHHCCHHE
VSGSGIVVADQNRMRQWNDYGFADRATPLALTGSAANAVVIGTGVARVLRLCDALRVPAC
ECCCEEEEECCHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHCCCCC
RDPVPAAPAGTSELPADIASLSQAEAAAKPKHGGGPARLELLTSNAYGAPNVADLSVIAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHH
QKQGVKQIDDMFVQMRLAQAQQLVYGSGPSAKVTSIVVQLKHTADLPAARARIQTLLRTR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEHHHCCCCHHHHHHHHHHHHHH
LAGEPLEVLGFATLNPQYGQVTGMFGAIFGFIAILIATIVLFTVGNTMNMAVMERTHEIG
HCCCCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TLRALGLRDAGIRRLFVCEGCLLGICGAAAGTVLALAAGVAINRAGLHWTPPGQTDPVAL
HEHEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCCCCCCEEE
SVRVWGEFGMIARYALGVTVVATLSAWLPAHRAARLPIVEALRFA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]