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The map label for this gene is degP [H]

Identifier: 238023978

GI number: 238023978

Start: 634931

End: 635761

Strand: Reverse

Name: degP [H]

Synonym: bglu_2g05280

Alternate gene names: 238023978

Gene position: 635761-634931 (Counterclockwise)

Preceding gene: 238023979

Following gene: 238023977

Centisome position: 22.49

GC content: 70.04

Gene sequence:

>831_bases
ATGATCGGCAGCGCGGTGCTGATCGCGCCGGGCCGCTTCATCACCGCCTGCCACGTGGTGGAGAAGTCGGTCGGCGTCAC
GCTGAGCAACGGCAACGCCACGCTGAAGGTGGACGAGGTGCTGCGCGACCCCGACGATCGCCGCGACCTGTGCCTGCTGC
GCGTGGCGGGCCGGCTCGACGCGGCGCCGGTGCAGATCGCGCCGATCAGCACGCTGAAGGTGGGGCAGCGCGTGTACGTG
ATCGCGAGTCCGCGCGGGCTCGAACTGTCGCTGACCGACGGGCTGATCTCGTCGCTGCGCCGGGAACCCGAGAGCCAGGT
GCCGATCATCCAGTCGTCCACGCCCGTCACGAGCGGCTCCAGCGGCGGCGGCCTGTTCGACGAGCACGGGCGGCTGGTGG
GCGTGGTGCGCTCGGTGGCGACCGCCACCGAGAATTTCGCGTTTTCCTATCCGGCCGAATGGGTCGCCCAGCTGCCCGAG
CGCTATGCACGCGAGATTGCCGCGTGGCAGAACGAGATGAAGGCCTCGGGCGTGCGTTTCTCCGGCGACGGCAACGTGGT
GGGCAGCGGCTTCGCCGCGCTCGCCGACCTCAACGCGCTACCGGTGCCGGCCGCGCAAAGGGAGCCGGTCGCGCTGGCCT
ACCGGCAGTTCCTGCTGCTCGCCGCGCCGCGCGCGTTCGTGTTTACGAGCGACGGCAAATTCGGCACGTTTTCGAACGCG
GCCGAATTCTCGAAGTTTCGGGCGCAATGCCGGCAGGCCGGCGTGACGTTCAAGCTCTACGCGGTGGACAACGCCGTGGT
GTGGCAGGCCGCGGCTGCGGCCGCGAGGTGA

Upstream 100 bases:

>100_bases
GTTTGCACAGGGCGCCGGGACGTCGGCCGAGCAGGTGTTCGCGGCCGTGTCGCCGAAGGTCTGGACGGTCAAGGCCGCGC
AGCCGCAAGGCAGCTAGTTC

Downstream 100 bases:

>100_bases
ACGGCAACGCGCGGCCAGCCGCTCGCGGCCTGCTCGCCCGCGAGGGCCAGCGCGAGCACGCGGGCGATCTCCGGGGCCGC
GTCGCATGCGCCAGCCCGAG

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MIGSAVLIAPGRFITACHVVEKSVGVTLSNGNATLKVDEVLRDPDDRRDLCLLRVAGRLDAAPVQIAPISTLKVGQRVYV
IASPRGLELSLTDGLISSLRREPESQVPIIQSSTPVTSGSSGGGLFDEHGRLVGVVRSVATATENFAFSYPAEWVAQLPE
RYAREIAAWQNEMKASGVRFSGDGNVVGSGFAALADLNALPVPAAQREPVALAYRQFLLLAAPRAFVFTSDGKFGTFSNA
AEFSKFRAQCRQAGVTFKLYAVDNAVVWQAAAAAAR

Sequences:

>Translated_276_residues
MIGSAVLIAPGRFITACHVVEKSVGVTLSNGNATLKVDEVLRDPDDRRDLCLLRVAGRLDAAPVQIAPISTLKVGQRVYV
IASPRGLELSLTDGLISSLRREPESQVPIIQSSTPVTSGSSGGGLFDEHGRLVGVVRSVATATENFAFSYPAEWVAQLPE
RYAREIAAWQNEMKASGVRFSGDGNVVGSGFAALADLNALPVPAAQREPVALAYRQFLLLAAPRAFVFTSDGKFGTFSNA
AEFSKFRAQCRQAGVTFKLYAVDNAVVWQAAAAAAR
>Mature_276_residues
MIGSAVLIAPGRFITACHVVEKSVGVTLSNGNATLKVDEVLRDPDDRRDLCLLRVAGRLDAAPVQIAPISTLKVGQRVYV
IASPRGLELSLTDGLISSLRREPESQVPIIQSSTPVTSGSSGGGLFDEHGRLVGVVRSVATATENFAFSYPAEWVAQLPE
RYAREIAAWQNEMKASGVRFSGDGNVVGSGFAALADLNALPVPAAQREPVALAYRQFLLLAAPRAFVFTSDGKFGTFSNA
AEFSKFRAQCRQAGVTFKLYAVDNAVVWQAAAAAAR

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Escherichia coli, GI1786356, Length=192, Percent_Identity=25.5208333333333, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 29352; Mature: 29352

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGSAVLIAPGRFITACHVVEKSVGVTLSNGNATLKVDEVLRDPDDRRDLCLLRVAGRLD
CCCCEEEEECCCHHHHHHHHHHHHCEEEECCCEEEEEHHHHCCCCCCCCEEEEEECCCCC
AAPVQIAPISTLKVGQRVYVIASPRGLELSLTDGLISSLRREPESQVPIIQSSTPVTSGS
CCCEEEECCCCEECCCEEEEEECCCCCEEEEHHHHHHHHHCCCCCCCCEEECCCCCCCCC
SGGGLFDEHGRLVGVVRSVATATENFAFSYPAEWVAQLPERYAREIAAWQNEMKASGVRF
CCCCCCHHCCHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
SGDGNVVGSGFAALADLNALPVPAAQREPVALAYRQFLLLAAPRAFVFTSDGKFGTFSNA
CCCCCEECCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCH
AEFSKFRAQCRQAGVTFKLYAVDNAVVWQAAAAAAR
HHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure
MIGSAVLIAPGRFITACHVVEKSVGVTLSNGNATLKVDEVLRDPDDRRDLCLLRVAGRLD
CCCCEEEEECCCHHHHHHHHHHHHCEEEECCCEEEEEHHHHCCCCCCCCEEEEEECCCCC
AAPVQIAPISTLKVGQRVYVIASPRGLELSLTDGLISSLRREPESQVPIIQSSTPVTSGS
CCCEEEECCCCEECCCEEEEEECCCCCEEEEHHHHHHHHHCCCCCCCCEEECCCCCCCCC
SGGGLFDEHGRLVGVVRSVATATENFAFSYPAEWVAQLPERYAREIAAWQNEMKASGVRF
CCCCCCHHCCHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
SGDGNVVGSGFAALADLNALPVPAAQREPVALAYRQFLLLAAPRAFVFTSDGKFGTFSNA
CCCCCEECCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCH
AEFSKFRAQCRQAGVTFKLYAVDNAVVWQAAAAAAR
HHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]