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The map label for this gene is ygbJ [H]

Identifier: 238023941

GI number: 238023941

Start: 586191

End: 587081

Strand: Reverse

Name: ygbJ [H]

Synonym: bglu_2g04900

Alternate gene names: 238023941

Gene position: 587081-586191 (Counterclockwise)

Preceding gene: 238023942

Following gene: 238023940

Centisome position: 20.76

GC content: 71.49

Gene sequence:

>891_bases
ATGTCACGACAAGTAGGCGTCATCGGGCTCGGCGCGATGGGACTCGGCGTGGCGCGCTCGCTGCTGCGCGCCGGATTCCG
CGTCCATGCCTGCGACGTGCGCCACAGCGTGCTCGACGCGTTCGCGGCCGAGGGCGGCATCCGCTGCGCCACCCCCGCCG
AACTGGGCGCGCGGTGCGAGGTGGTGATCACGCTGGTGGTCGACGCGGCCCAGACCGACACCGTGCTGTTCGGCGAGCAC
GGTGCGGTGCCGGCCATGCGGCCCGGCACGGTGGTGATCTCGAGCGCCACGGTCGCGCCGGAATTCGCGCAGCAGCTCGG
CGCGCGCGTCGAGGCGGCCGGCCTGCTGATGCTCGATGCGCCGGTATCCGGCGGTGCCGCGCGCGCGGCCTCGGGCCAGA
TGACGATGATGAGCTCGGGGCCGGCGGCCGCCTACGCGGCCTGCGAGGACGTGCTCGCGGCGATCTCGGCCAAGCTCTAC
CGGCTCGGCGCCGAGCATGGCGCGGGCTCGAAGGTGAAGATCATCAACCAGCTGCTGGCCGGCGTGCATATCGCGGCGGC
CGCCGAGGCGATGGCGCTCGGACTGCGCGAGGGCGTGGACGCCGACGCGCTCTACGAGGTGATCACGCACAGCGCCGGCA
ACTCCTGGATGTTCGAGAACCGCGTGCCGCATATCCTGAACGGCGACTACGCGCCGCTTTCCGCCGTCGACATCTTCGTC
AAGGATCTCGGCCTGGTGCTCGATACCGCGCGCCGCAGCAAGTTCCCGCTGCCGCTGTCGGCCACCGCGCACCAGATGTT
CATGAACGCGTCGAGCGCCGGCCACGGCGGCGAGGACGATTCCGCCGTGATCAAGACCTTCCCCGGCATCACGCTGCCAC
CGGCGCGCTGA

Upstream 100 bases:

>100_bases
GCATCCATCTGGTGAACGCCGCGCGGCGCCTGGCGCAGGCGGGCCTGGGCTGATCCATTCGTCCGGCGAAGCCGGGCATC
TGTTCGATACAAGGATTCAC

Downstream 100 bases:

>100_bases
AGCGCCGAACCGCGCCACTCGTGCTCATCGTCATGACCGACTCCGCCACCCCCGCCCGTCCGCTGCTCGGCTGCATCGCC
GACGATTTCACCGGCGCGAC

Product: 3-hydroxyisobutyrate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSRQVGVIGLGAMGLGVARSLLRAGFRVHACDVRHSVLDAFAAEGGIRCATPAELGARCEVVITLVVDAAQTDTVLFGEH
GAVPAMRPGTVVISSATVAPEFAQQLGARVEAAGLLMLDAPVSGGAARAASGQMTMMSSGPAAAYAACEDVLAAISAKLY
RLGAEHGAGSKVKIINQLLAGVHIAAAAEAMALGLREGVDADALYEVITHSAGNSWMFENRVPHILNGDYAPLSAVDIFV
KDLGLVLDTARRSKFPLPLSATAHQMFMNASSAGHGGEDDSAVIKTFPGITLPPAR

Sequences:

>Translated_296_residues
MSRQVGVIGLGAMGLGVARSLLRAGFRVHACDVRHSVLDAFAAEGGIRCATPAELGARCEVVITLVVDAAQTDTVLFGEH
GAVPAMRPGTVVISSATVAPEFAQQLGARVEAAGLLMLDAPVSGGAARAASGQMTMMSSGPAAAYAACEDVLAAISAKLY
RLGAEHGAGSKVKIINQLLAGVHIAAAAEAMALGLREGVDADALYEVITHSAGNSWMFENRVPHILNGDYAPLSAVDIFV
KDLGLVLDTARRSKFPLPLSATAHQMFMNASSAGHGGEDDSAVIKTFPGITLPPAR
>Mature_295_residues
SRQVGVIGLGAMGLGVARSLLRAGFRVHACDVRHSVLDAFAAEGGIRCATPAELGARCEVVITLVVDAAQTDTVLFGEHG
AVPAMRPGTVVISSATVAPEFAQQLGARVEAAGLLMLDAPVSGGAARAASGQMTMMSSGPAAAYAACEDVLAAISAKLYR
LGAEHGAGSKVKIINQLLAGVHIAAAAEAMALGLREGVDADALYEVITHSAGNSWMFENRVPHILNGDYAPLSAVDIFVK
DLGLVLDTARRSKFPLPLSATAHQMFMNASSAGHGGEDDSAVIKTFPGITLPPAR

Specific function: Unknown

COG id: COG2084

COG function: function code I; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyisobutyrate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI23308751, Length=288, Percent_Identity=30.9027777777778, Blast_Score=148, Evalue=5e-36,
Organism=Homo sapiens, GI40556376, Length=285, Percent_Identity=25.6140350877193, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1789092, Length=294, Percent_Identity=52.7210884353742, Blast_Score=281, Evalue=4e-77,
Organism=Escherichia coli, GI145693186, Length=280, Percent_Identity=31.4285714285714, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1790315, Length=282, Percent_Identity=30.1418439716312, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786719, Length=282, Percent_Identity=26.241134751773, Blast_Score=115, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17557316, Length=273, Percent_Identity=32.6007326007326, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24655230, Length=289, Percent_Identity=31.8339100346021, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI19922568, Length=289, Percent_Identity=31.8339100346021, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28574115, Length=280, Percent_Identity=23.2142857142857, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002204
- InterPro:   IPR015815
- InterPro:   IPR008927
- InterPro:   IPR006115
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF03446 NAD_binding_2 [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 30350; Mature: 30219

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQVGVIGLGAMGLGVARSLLRAGFRVHACDVRHSVLDAFAAEGGIRCATPAELGARCE
CCCCCEEEEECHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEECCHHHHCCCEE
VVITLVVDAAQTDTVLFGEHGAVPAMRPGTVVISSATVAPEFAQQLGARVEAAGLLMLDA
EEEEEEEECCCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCHHCCEEEEEC
PVSGGAARAASGQMTMMSSGPAAAYAACEDVLAAISAKLYRLGAEHGAGSKVKIINQLLA
CCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GVHIAAAAEAMALGLREGVDADALYEVITHSAGNSWMFENRVPHILNGDYAPLSAVDIFV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCHHCCCCCCCHHHHHHHH
KDLGLVLDTARRSKFPLPLSATAHQMFMNASSAGHGGEDDSAVIKTFPGITLPPAR
HHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SRQVGVIGLGAMGLGVARSLLRAGFRVHACDVRHSVLDAFAAEGGIRCATPAELGARCE
CCCCEEEEECHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCEECCHHHHCCCEE
VVITLVVDAAQTDTVLFGEHGAVPAMRPGTVVISSATVAPEFAQQLGARVEAAGLLMLDA
EEEEEEEECCCCCEEEECCCCCCCCCCCCEEEEECCCCCHHHHHHHCCCCHHCCEEEEEC
PVSGGAARAASGQMTMMSSGPAAAYAACEDVLAAISAKLYRLGAEHGAGSKVKIINQLLA
CCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GVHIAAAAEAMALGLREGVDADALYEVITHSAGNSWMFENRVPHILNGDYAPLSAVDIFV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCHHCCCCCCCHHHHHHHH
KDLGLVLDTARRSKFPLPLSATAHQMFMNASSAGHGGEDDSAVIKTFPGITLPPAR
HHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]