Click here to switch to the map view.

The map label for this gene is gudP [H]

Identifier: 238023832

GI number: 238023832

Start: 438459

End: 439820

Strand: Reverse

Name: gudP [H]

Synonym: bglu_2g03700

Alternate gene names: 238023832

Gene position: 439820-438459 (Counterclockwise)

Preceding gene: 238023834

Following gene: 238023831

Centisome position: 15.56

GC content: 68.94

Gene sequence:

>1362_bases
ATGGAAGCGACCCGCACCGCCAATCCGGCCGCCACGGCCAAACGGACCGCCGTCCGCTACTGGATCCTGCTGATGATCTT
CGTCGTGACGACGCTGAACTACGCGGATCGCGCGACGCTGTCGATCACCGGCACCTCGATGCGCAAGGAGTTCGGCATCG
ACGCGGTGCAGATGGGCTACATCTTCTCGTCGTTCAGCTGGGCCTACGTGCTCGCGCAGCTGCCGAGCGGCTGGCTGCTG
GACCGCTTCGGCGCGCGCCGCGTGTACGCCGGCAGCATCTTCCTCTGGTCGCTGTTCACCCTGCTGCAGAGCACGATCGG
CCTGGCCGGCAGCGCCGCGCTGGCGGTGGCCGCGCTGTTCGTGCTGCGCTTCGCGGTGGGCATCGCCGAGGCGCCGGCGT
TCCCGGCCAATGCCAAGGTGGTGGCGAGCTGGTTCCCGACCAGCGAGCGCGGCACGGCATCGGCGATCTTCAATGCGGCG
CAGTATTTCGCGGCCGTGCTGTTCACGCCGCTGATGGCCTGGCTCACGCACGCGTTCAGCTGGCACCAGGTGTATCTGTG
GCTCGGCGCGGCCGGCATGGCGCTCGCGCTGCTGTGGATGCGGGTGGTGCGCAGCCCGGCCGATCACCCGCGCGTGAATC
GGGCCGAGCGCGAGCACATCGAGCAGGGCGGCGGCGTGATCGAGACCGGCGGCAAGACGCCCGCCGGCGGCGCGCCCGAG
CGGCTCGCGGGCTGGTTCTACGTGCGCCAGCTGCTCGGCAACCGGATGCTGATCGGCGTCTATCTCGGCCAGTACTGCAT
CAACGTGCTCACCTACTTCTTCCTGACCTGGTTCCCGATCTACCTCGTGCAGGCGCGCGGCATGTCGATCCTGAAGGCCG
GCGTGCTGGCCTCGCTGCCGGCCGTCTGCGGCTTCCTCGGCGGGGTGCTGGGCGGCATGCTGTCGGACGGCATGATCCGG
CGCGGCGTGTCGCTCACGCGTGCGCGCAAGATCCCGATCATCGGCGGCATGCTGCTGTCGATGGCGATCATCGGCTGCAA
CTACGTGGACAGCGCCGCGCTCGTGATCGCGCTGATGGCACTGTCGTTCTTCGGCAAGGGCCTGGGCTCGCTGGGCTGGG
CGGTGGTGGCCGACACGGCGCCGAAGGAGGCCATCGGCCTGTCGGGCAGCCTCTTCAACATGTTCGGCAACGCGGCCGGG
ATCGTCACGCCGATCGTGATCGGCTACCTGGTGGGCGCGAGCGGCTCGTTCAACGGCGCCCTGCTATTCGTCGGGCTCAA
CGCGCTGGTGACCGTGCTCTGCTACCTCGTGATCGTCAAGGACATCAGGCGCGTGACGCTGCGCAAGGCACCCGGCCGCT
GA

Upstream 100 bases:

>100_bases
AGGCGCGTCACCGTCGCGGTCCTAGACTGTCAAGTTGTACGACGACATATCAGTCAGCATTAGACCGACGGACTCCTCTC
GCGCTCTCGCCAGGACACTC

Downstream 100 bases:

>100_bases
GGCGATGCCGACAGGGGCGGCGCGGCTCGCGCGCCGTCGAGCGGCCGCCGCACGGCGGCTCGCGATCGCGCCCGGATGAC
CGGCAGCCGATCCTTGACGG

Product: D-galactonate transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MEATRTANPAATAKRTAVRYWILLMIFVVTTLNYADRATLSITGTSMRKEFGIDAVQMGYIFSSFSWAYVLAQLPSGWLL
DRFGARRVYAGSIFLWSLFTLLQSTIGLAGSAALAVAALFVLRFAVGIAEAPAFPANAKVVASWFPTSERGTASAIFNAA
QYFAAVLFTPLMAWLTHAFSWHQVYLWLGAAGMALALLWMRVVRSPADHPRVNRAEREHIEQGGGVIETGGKTPAGGAPE
RLAGWFYVRQLLGNRMLIGVYLGQYCINVLTYFFLTWFPIYLVQARGMSILKAGVLASLPAVCGFLGGVLGGMLSDGMIR
RGVSLTRARKIPIIGGMLLSMAIIGCNYVDSAALVIALMALSFFGKGLGSLGWAVVADTAPKEAIGLSGSLFNMFGNAAG
IVTPIVIGYLVGASGSFNGALLFVGLNALVTVLCYLVIVKDIRRVTLRKAPGR

Sequences:

>Translated_453_residues
MEATRTANPAATAKRTAVRYWILLMIFVVTTLNYADRATLSITGTSMRKEFGIDAVQMGYIFSSFSWAYVLAQLPSGWLL
DRFGARRVYAGSIFLWSLFTLLQSTIGLAGSAALAVAALFVLRFAVGIAEAPAFPANAKVVASWFPTSERGTASAIFNAA
QYFAAVLFTPLMAWLTHAFSWHQVYLWLGAAGMALALLWMRVVRSPADHPRVNRAEREHIEQGGGVIETGGKTPAGGAPE
RLAGWFYVRQLLGNRMLIGVYLGQYCINVLTYFFLTWFPIYLVQARGMSILKAGVLASLPAVCGFLGGVLGGMLSDGMIR
RGVSLTRARKIPIIGGMLLSMAIIGCNYVDSAALVIALMALSFFGKGLGSLGWAVVADTAPKEAIGLSGSLFNMFGNAAG
IVTPIVIGYLVGASGSFNGALLFVGLNALVTVLCYLVIVKDIRRVTLRKAPGR
>Mature_453_residues
MEATRTANPAATAKRTAVRYWILLMIFVVTTLNYADRATLSITGTSMRKEFGIDAVQMGYIFSSFSWAYVLAQLPSGWLL
DRFGARRVYAGSIFLWSLFTLLQSTIGLAGSAALAVAALFVLRFAVGIAEAPAFPANAKVVASWFPTSERGTASAIFNAA
QYFAAVLFTPLMAWLTHAFSWHQVYLWLGAAGMALALLWMRVVRSPADHPRVNRAEREHIEQGGGVIETGGKTPAGGAPE
RLAGWFYVRQLLGNRMLIGVYLGQYCINVLTYFFLTWFPIYLVQARGMSILKAGVLASLPAVCGFLGGVLGGMLSDGMIR
RGVSLTRARKIPIIGGMLLSMAIIGCNYVDSAALVIALMALSFFGKGLGSLGWAVVADTAPKEAIGLSGSLFNMFGNAAG
IVTPIVIGYLVGASGSFNGALLFVGLNALVTVLCYLVIVKDIRRVTLRKAPGR

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=388, Percent_Identity=25.5154639175258, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI9945322, Length=433, Percent_Identity=25.4041570438799, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI21322234, Length=392, Percent_Identity=24.234693877551, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI6912666, Length=379, Percent_Identity=25.5936675461741, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI4885441, Length=364, Percent_Identity=25.5494505494505, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI5031955, Length=292, Percent_Identity=26.027397260274, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI148743791, Length=386, Percent_Identity=25.6476683937824, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI223718438, Length=196, Percent_Identity=25.5102040816327, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI154350196, Length=419, Percent_Identity=24.1050119331742, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI148728191, Length=329, Percent_Identity=24.6200607902736, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI256219598, Length=384, Percent_Identity=25.5208333333333, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503847, Length=384, Percent_Identity=25.5208333333333, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI256219483, Length=384, Percent_Identity=25.5208333333333, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI154800443, Length=339, Percent_Identity=20.6489675516224, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI256219543, Length=296, Percent_Identity=26.3513513513513, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1789152, Length=444, Percent_Identity=58.7837837837838, Blast_Score=561, Evalue=1e-161,
Organism=Escherichia coli, GI1789515, Length=436, Percent_Identity=56.8807339449541, Blast_Score=523, Evalue=1e-150,
Organism=Escherichia coli, GI87082320, Length=440, Percent_Identity=40.2272727272727, Blast_Score=340, Evalue=9e-95,
Organism=Escherichia coli, GI2367379, Length=422, Percent_Identity=29.6208530805687, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI2367193, Length=330, Percent_Identity=28.1818181818182, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788573, Length=448, Percent_Identity=22.7678571428571, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI115533556, Length=446, Percent_Identity=25.5605381165919, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI115533554, Length=437, Percent_Identity=25.629290617849, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17552542, Length=383, Percent_Identity=25.8485639686684, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560030, Length=359, Percent_Identity=22.5626740947075, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71997452, Length=379, Percent_Identity=24.802110817942, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193205400, Length=281, Percent_Identity=22.0640569395018, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI32565916, Length=285, Percent_Identity=21.4035087719298, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI32565914, Length=285, Percent_Identity=21.4035087719298, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17535049, Length=413, Percent_Identity=23.2445520581114, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25151055, Length=244, Percent_Identity=23.3606557377049, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17554148, Length=363, Percent_Identity=23.6914600550964, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=364, Percent_Identity=23.6263736263736, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=364, Percent_Identity=23.6263736263736, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537329, Length=286, Percent_Identity=24.4755244755245, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641682, Length=432, Percent_Identity=25.6944444444444, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24639764, Length=441, Percent_Identity=24.9433106575964, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI45550460, Length=422, Percent_Identity=25.5924170616114, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24583789, Length=393, Percent_Identity=26.2086513994911, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24584153, Length=371, Percent_Identity=26.1455525606469, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24655255, Length=376, Percent_Identity=26.063829787234, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28573299, Length=407, Percent_Identity=25.5528255528256, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI19922400, Length=459, Percent_Identity=24.1830065359477, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24654215, Length=435, Percent_Identity=24.367816091954, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648416, Length=397, Percent_Identity=25.1889168765743, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21356189, Length=397, Percent_Identity=25.1889168765743, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573708, Length=445, Percent_Identity=24.7191011235955, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573707, Length=445, Percent_Identity=24.7191011235955, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20130135, Length=431, Percent_Identity=23.2018561484919, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24655271, Length=411, Percent_Identity=23.1143552311436, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI20130167, Length=408, Percent_Identity=23.5294117647059, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24580790, Length=390, Percent_Identity=23.5897435897436, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24653727, Length=384, Percent_Identity=24.7395833333333, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI20129235, Length=399, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550364, Length=445, Percent_Identity=24.9438202247191, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI62484226, Length=365, Percent_Identity=24.1095890410959, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24658696, Length=425, Percent_Identity=26.1176470588235, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221474708, Length=158, Percent_Identity=29.746835443038, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48567; Mature: 48567

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEATRTANPAATAKRTAVRYWILLMIFVVTTLNYADRATLSITGTSMRKEFGIDAVQMGY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHCCCHHHHHH
IFSSFSWAYVLAQLPSGWLLDRFGARRVYAGSIFLWSLFTLLQSTIGLAGSAALAVAALF
HHHHHHHHHHHHHCCCCHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VLRFAVGIAEAPAFPANAKVVASWFPTSERGTASAIFNAAQYFAAVLFTPLMAWLTHAFS
HHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WHQVYLWLGAAGMALALLWMRVVRSPADHPRVNRAEREHIEQGGGVIETGGKTPAGGAPE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCHH
RLAGWFYVRQLLGNRMLIGVYLGQYCINVLTYFFLTWFPIYLVQARGMSILKAGVLASLP
HHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AVCGFLGGVLGGMLSDGMIRRGVSLTRARKIPIIGGMLLSMAIIGCNYVDSAALVIALMA
HHHHHHHHHHHHHHHCHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LSFFGKGLGSLGWAVVADTAPKEAIGLSGSLFNMFGNAAGIVTPIVIGYLVGASGSFNGA
HHHHHCCHHHCCCEEEECCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCE
LLFVGLNALVTVLCYLVIVKDIRRVTLRKAPGR
EEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEATRTANPAATAKRTAVRYWILLMIFVVTTLNYADRATLSITGTSMRKEFGIDAVQMGY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHCCCHHHHHH
IFSSFSWAYVLAQLPSGWLLDRFGARRVYAGSIFLWSLFTLLQSTIGLAGSAALAVAALF
HHHHHHHHHHHHHCCCCHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VLRFAVGIAEAPAFPANAKVVASWFPTSERGTASAIFNAAQYFAAVLFTPLMAWLTHAFS
HHHHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WHQVYLWLGAAGMALALLWMRVVRSPADHPRVNRAEREHIEQGGGVIETGGKTPAGGAPE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCHH
RLAGWFYVRQLLGNRMLIGVYLGQYCINVLTYFFLTWFPIYLVQARGMSILKAGVLASLP
HHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AVCGFLGGVLGGMLSDGMIRRGVSLTRARKIPIIGGMLLSMAIIGCNYVDSAALVIALMA
HHHHHHHHHHHHHHHCHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LSFFGKGLGSLGWAVVADTAPKEAIGLSGSLFNMFGNAAGIVTPIVIGYLVGASGSFNGA
HHHHHCCHHHCCCEEEECCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCE
LLFVGLNALVTVLCYLVIVKDIRRVTLRKAPGR
EEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]