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The map label for this gene is vanA [H]

Identifier: 238023772

GI number: 238023772

Start: 356294

End: 357418

Strand: Reverse

Name: vanA [H]

Synonym: bglu_2g03040

Alternate gene names: 238023772

Gene position: 357418-356294 (Counterclockwise)

Preceding gene: 238023775

Following gene: 238023765

Centisome position: 12.64

GC content: 66.4

Gene sequence:

>1125_bases
ATGCATGCAGTGCCCTTGTCGCAGCCCGACGATGTGATCGAACCGACCGCCACCGCGCCCGTGCGTGATCTGCGCCGCGT
GCCCATCCACCCCGACTTCTGGTATCCGCTCGCCTGGTCGCGCGAACTGAAGCGCGGCAAGACGCTCGGCGTGCATTTCG
CCGGCGATCCGATCGTGCTGTTTCGTGGCGACTCGGGCACGGTATTTGCGCTCGAGGACCGCTGCGCGCACCGCCAGGTG
CCGCTGCATGCGGGCGTGGTGGACGGCGACGCGCTGCGCTGCGGCTACCACGGCTGGACCTACGACTGCAGCGGCAAGTG
CGTGGACGTGCCCTACCTCGGCAAGGAGCGGCTGCCCAACGGCGTGCGCTCGTATCCGTGCCGCGAGGTGCAGGGCCTGA
TCTTCGTGTTCACCGGCGATTTGGCGCTGGCCGACGAGAAGCCGGTGCCGGCGCTTCCCACCGTGTCGGACCCGAAATAC
AAGACGCGCCGTTTCGGCCGCGAGGTGAAGTGTCATTACTCGTTCATGCACGAGAACCTGATGGACATGAACCACCAGTT
CCTGCATCGCCGCGAGATGGGCCAGATGAAGGCGCGCTCGCTGGGCCGCCGGCGCGGCGAGGGCTGGGTGGAAGTGGACT
ACACCTTCTCGCGCGCCGAGGGCAAGCAGCCGATCGGCGAGGCGCTGGTGTTCGGCGCCAGCAAGAAGCCGCAGGATCAG
AGCGACAAGAGCGTGATGACGATCCGCACCGAATACCCGTACCAGACGCTGAAGATCCTCTCCAGCGAAGGCACGCTGGT
GATGGACCTGTGGATCGTCTACGTGCCGCTCGACAGGCAGCAGCGCACCAACCGCACGTTCGGCATGCTGTCGATCCGCA
AGCCCTCGTTTCCGTTCGCGCTGGACCTGGCCTGGCCGCTGCTGGTGTGGTTTACCGAGCGGATCTTCAAGGAGGATCGC
TGGATCGTCGAGCGCGAGCAGGAAGCGCACGACATGCAAGGCGAGGACTGGAACCACGAGGTGTTCCCCGTCATCAACGA
CCTGCGCGACGTGCTGCGCAACAACGGCGCGCGCACCGTGATCCCGATCCTCAACCTGGGCGCCGAACCGCGGCCCGCCG
CCTGA

Upstream 100 bases:

>100_bases
GCTCGCCGCACGAAGGCGAGTTTCGCGTAAACTGCGCCAGATCCTCCCTTCGCGCTAGGCCGCGTAGGTCGAAGCACCGT
ATTGCCAGGAGATGCCCCGC

Downstream 100 bases:

>100_bases
AGCAGGCCCCCTGCCCTCTCCTGCGCTGATCGGCGGGCGCGACTTGGCCCGCGCCCGCGCCGTGTCCGCGCACCACGCAC
CGCGCCGTCAGGCGGCGAAC

Product: phenylpropionate dioxygenase

Products: NA

Alternate protein names: 4-hydroxy-3-methoxybenzoate demethylase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MHAVPLSQPDDVIEPTATAPVRDLRRVPIHPDFWYPLAWSRELKRGKTLGVHFAGDPIVLFRGDSGTVFALEDRCAHRQV
PLHAGVVDGDALRCGYHGWTYDCSGKCVDVPYLGKERLPNGVRSYPCREVQGLIFVFTGDLALADEKPVPALPTVSDPKY
KTRRFGREVKCHYSFMHENLMDMNHQFLHRREMGQMKARSLGRRRGEGWVEVDYTFSRAEGKQPIGEALVFGASKKPQDQ
SDKSVMTIRTEYPYQTLKILSSEGTLVMDLWIVYVPLDRQQRTNRTFGMLSIRKPSFPFALDLAWPLLVWFTERIFKEDR
WIVEREQEAHDMQGEDWNHEVFPVINDLRDVLRNNGARTVIPILNLGAEPRPAA

Sequences:

>Translated_374_residues
MHAVPLSQPDDVIEPTATAPVRDLRRVPIHPDFWYPLAWSRELKRGKTLGVHFAGDPIVLFRGDSGTVFALEDRCAHRQV
PLHAGVVDGDALRCGYHGWTYDCSGKCVDVPYLGKERLPNGVRSYPCREVQGLIFVFTGDLALADEKPVPALPTVSDPKY
KTRRFGREVKCHYSFMHENLMDMNHQFLHRREMGQMKARSLGRRRGEGWVEVDYTFSRAEGKQPIGEALVFGASKKPQDQ
SDKSVMTIRTEYPYQTLKILSSEGTLVMDLWIVYVPLDRQQRTNRTFGMLSIRKPSFPFALDLAWPLLVWFTERIFKEDR
WIVEREQEAHDMQGEDWNHEVFPVINDLRDVLRNNGARTVIPILNLGAEPRPAA
>Mature_374_residues
MHAVPLSQPDDVIEPTATAPVRDLRRVPIHPDFWYPLAWSRELKRGKTLGVHFAGDPIVLFRGDSGTVFALEDRCAHRQV
PLHAGVVDGDALRCGYHGWTYDCSGKCVDVPYLGKERLPNGVRSYPCREVQGLIFVFTGDLALADEKPVPALPTVSDPKY
KTRRFGREVKCHYSFMHENLMDMNHQFLHRREMGQMKARSLGRRRGEGWVEVDYTFSRAEGKQPIGEALVFGASKKPQDQ
SDKSVMTIRTEYPYQTLKILSSEGTLVMDLWIVYVPLDRQQRTNRTFGMLSIRKPSFPFALDLAWPLLVWFTERIFKEDR
WIVEREQEAHDMQGEDWNHEVFPVINDLRDVLRNNGARTVIPILNLGAEPRPAA

Specific function: Part Of The Multicomponent 3-Phenylpropionate Dioxygenase. Converts 3-Phenylpropionic Acid (Pp) Into Cis-3-(3- Carboxyethyl)-3,5-Cyclohexadiene-1,2-Diol (Pp-Dihydrodiol). [C]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71983709, Length=181, Percent_Identity=29.2817679558011, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI161085896, Length=173, Percent_Identity=27.7456647398844, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941
- InterPro:   IPR015881 [H]

Pfam domain/function: PF00355 Rieske [H]

EC number: =1.14.13.82 [H]

Molecular weight: Translated: 42885; Mature: 42885

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAVPLSQPDDVIEPTATAPVRDLRRVPIHPDFWYPLAWSRELKRGKTLGVHFAGDPIVL
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCEEEE
FRGDSGTVFALEDRCAHRQVPLHAGVVDGDALRCGYHGWTYDCSGKCVDVPYLGKERLPN
EECCCCCEEEECCCCCCCCCCCCCCEECCCEEEECCCCCEEECCCCEEECCCCCHHHCCC
GVRSYPCREVQGLIFVFTGDLALADEKPVPALPTVSDPKYKTRRFGREVKCHYSFMHENL
CHHCCCCHHHCCEEEEEECCEEECCCCCCCCCCCCCCCCHHHHHCCCCEEEHHHHHHHHH
MDMNHQFLHRREMGQMKARSLGRRRGEGWVEVDYTFSRAEGKQPIGEALVFGASKKPQDQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHEECCCCCCCCC
SDKSVMTIRTEYPYQTLKILSSEGTLVMDLWIVYVPLDRQQRTNRTFGMLSIRKPSFPFA
CCCEEEEEEECCCHHEEEEECCCCCEEEEEEEEEEECCCHHHCCCCEEEEEEECCCCCEE
LDLAWPLLVWFTERIFKEDRWIVEREQEAHDMQGEDWNHEVFPVINDLRDVLRNNGARTV
EHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
IPILNLGAEPRPAA
EEEECCCCCCCCCC
>Mature Secondary Structure
MHAVPLSQPDDVIEPTATAPVRDLRRVPIHPDFWYPLAWSRELKRGKTLGVHFAGDPIVL
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCEEEE
FRGDSGTVFALEDRCAHRQVPLHAGVVDGDALRCGYHGWTYDCSGKCVDVPYLGKERLPN
EECCCCCEEEECCCCCCCCCCCCCCEECCCEEEECCCCCEEECCCCEEECCCCCHHHCCC
GVRSYPCREVQGLIFVFTGDLALADEKPVPALPTVSDPKYKTRRFGREVKCHYSFMHENL
CHHCCCCHHHCCEEEEEECCEEECCCCCCCCCCCCCCCCHHHHHCCCCEEEHHHHHHHHH
MDMNHQFLHRREMGQMKARSLGRRRGEGWVEVDYTFSRAEGKQPIGEALVFGASKKPQDQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHEECCCCCCCCC
SDKSVMTIRTEYPYQTLKILSSEGTLVMDLWIVYVPLDRQQRTNRTFGMLSIRKPSFPFA
CCCEEEEEEECCCHHEEEEECCCCCEEEEEEEEEEECCCHHHCCCCEEEEEEECCCCCEE
LDLAWPLLVWFTERIFKEDRWIVEREQEAHDMQGEDWNHEVFPVINDLRDVLRNNGARTV
EHHHHHHHHHHHHHHHHCCCCEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
IPILNLGAEPRPAA
EEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3170489 [H]