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The map label for this gene is gltT [H]

Identifier: 238023768

GI number: 238023768

Start: 351760

End: 353046

Strand: Direct

Name: gltT [H]

Synonym: bglu_2g03000

Alternate gene names: 238023768

Gene position: 351760-353046 (Clockwise)

Preceding gene: 238023767

Following gene: 238023769

Centisome position: 12.44

GC content: 69.15

Gene sequence:

>1287_bases
ATGAAATCACGCCTCACCTTCTGGATCGCCGCGGGCATCGTGCTCGGCGGCGTCGCCGGCTACCTGTGCCATGCGAACGC
GGCCGACGCCGCGCAGGCCAAATCGATCGCGGGCTATTTCGGCATCCTGACCGACATCTTCCTGCGTCTGATCAAGATGA
TCATCGCACCGCTGGTGTTCGCCACGCTGGTCTCGGGTCTCGCCGGCATGGAGGGCGGCCGCGACGTCGGGCGCATCGGC
GCGCGCACGGTGGCATGGTTCTTCTGCGCGTCGTTCGTCTCGCTGCTGATCGGGCTGGTGTTCGCGAACCTGCTGCAGCC
CGGCGCCGGCCTGCATCTGACGGCCGGTCCCGACGACATCGTGGCCGGCCTCGACACGGCCGCGCTGAACGTGCGGGACG
TGCTCACCCATGCGTTCCCGACCAGCCTGCTCGACGCGATGGCGCGCAACGACATCCTGCAGATCCTGGTGTTCTCGGTG
TTCTTCGGGCTGGGGCTCGGCGCGCTGAAACGCGATCCGCGCGTCGCGCTGCTGGTCACGGCGGTCGACGGCCTGGTGCC
GGTGATGCTGCGCCTGACGGGCTATGTGATGCTGGCCGCGCCGATCGGCGTGTTCGGCGCGGTGGCCTCGGCCGTCACGC
TGCGCGGGCTCGACGTGATCCTGACCTACGGCAAGCTGATCGGCGCGTTCTATGCCGCGCTGCTGCTGCTGTGGGTGCTG
CTGGCGGGCGTCGGCTACCTGTTCCTCGGCCGCGGCGTGCTCGGCCTGCTGAAGGCGGTGCGCGAGCCGGCGCTGCTGGC
GTTCTCGACGGCCAGCAGCGAGGCCGCCTATCCGCGCCTGATCGAGCAGCTGGAGCGCTTCGGCATCCCGCAGAAGGTGG
TGGGCTTCACGCTGCCGCTCGGCTATGCGTTCAACCTCGACGGCTCGATGATGTACCAGTCGTTCGCGGCGATCTTCATC
GCCCAGGCGTTCGGCATCGACATGCCGCTTACGCAGCAGTTCGCGATGCTGCTGGTGCTGATGCTCAGCAGCAAGGGCAT
GGCGGGCGTGCCGCGCGGCTCGGTGGTGGTGGTCGCGGCGGTCGCGCCGATGTTCCATCTGCCGGCGGCCGGCGTCGCGC
TGGTGCTCGCGATCGACCAGATCCTCGACATGGGCCGCACCATGACGAACGTGATCGGCAACAGCGTGGCGACGGCCGTG
ATCGCGAAATGGGAGGGGCGGCGCGAGGCGGGGGCCGCCGATGCGGCGCATTTCGAACGCGAGCGGCTGCCGGGCGAGTC
GCAATGA

Upstream 100 bases:

>100_bases
CGATGCCGATCTGGCATCCGTCGCCGTCCTGCTTTTCCTTTTCCATCACAACGCGCTGCGCGGCGCCTCGCGCCCGCCCG
GCACCCTACCGGGGACGGAC

Downstream 100 bases:

>100_bases
TGGCCGCGCCGACACCCGCGGCCGGCGCGCGGCGGCGCTACGGCATCGTCGGCGGCCTTGGGCCGCTGGCGGGCGCCGAC
GTGTTCGGCAAGCTGATGCG

Product: Sodium:dicarboxylate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MKSRLTFWIAAGIVLGGVAGYLCHANAADAAQAKSIAGYFGILTDIFLRLIKMIIAPLVFATLVSGLAGMEGGRDVGRIG
ARTVAWFFCASFVSLLIGLVFANLLQPGAGLHLTAGPDDIVAGLDTAALNVRDVLTHAFPTSLLDAMARNDILQILVFSV
FFGLGLGALKRDPRVALLVTAVDGLVPVMLRLTGYVMLAAPIGVFGAVASAVTLRGLDVILTYGKLIGAFYAALLLLWVL
LAGVGYLFLGRGVLGLLKAVREPALLAFSTASSEAAYPRLIEQLERFGIPQKVVGFTLPLGYAFNLDGSMMYQSFAAIFI
AQAFGIDMPLTQQFAMLLVLMLSSKGMAGVPRGSVVVVAAVAPMFHLPAAGVALVLAIDQILDMGRTMTNVIGNSVATAV
IAKWEGRREAGAADAAHFERERLPGESQ

Sequences:

>Translated_428_residues
MKSRLTFWIAAGIVLGGVAGYLCHANAADAAQAKSIAGYFGILTDIFLRLIKMIIAPLVFATLVSGLAGMEGGRDVGRIG
ARTVAWFFCASFVSLLIGLVFANLLQPGAGLHLTAGPDDIVAGLDTAALNVRDVLTHAFPTSLLDAMARNDILQILVFSV
FFGLGLGALKRDPRVALLVTAVDGLVPVMLRLTGYVMLAAPIGVFGAVASAVTLRGLDVILTYGKLIGAFYAALLLLWVL
LAGVGYLFLGRGVLGLLKAVREPALLAFSTASSEAAYPRLIEQLERFGIPQKVVGFTLPLGYAFNLDGSMMYQSFAAIFI
AQAFGIDMPLTQQFAMLLVLMLSSKGMAGVPRGSVVVVAAVAPMFHLPAAGVALVLAIDQILDMGRTMTNVIGNSVATAV
IAKWEGRREAGAADAAHFERERLPGESQ
>Mature_428_residues
MKSRLTFWIAAGIVLGGVAGYLCHANAADAAQAKSIAGYFGILTDIFLRLIKMIIAPLVFATLVSGLAGMEGGRDVGRIG
ARTVAWFFCASFVSLLIGLVFANLLQPGAGLHLTAGPDDIVAGLDTAALNVRDVLTHAFPTSLLDAMARNDILQILVFSV
FFGLGLGALKRDPRVALLVTAVDGLVPVMLRLTGYVMLAAPIGVFGAVASAVTLRGLDVILTYGKLIGAFYAALLLLWVL
LAGVGYLFLGRGVLGLLKAVREPALLAFSTASSEAAYPRLIEQLERFGIPQKVVGFTLPLGYAFNLDGSMMYQSFAAIFI
AQAFGIDMPLTQQFAMLLVLMLSSKGMAGVPRGSVVVVAAVAPMFHLPAAGVALVLAIDQILDMGRTMTNVIGNSVATAV
IAKWEGRREAGAADAAHFERERLPGESQ

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI169790839, Length=466, Percent_Identity=24.4635193133047, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI21314632, Length=441, Percent_Identity=24.9433106575964, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI66773030, Length=465, Percent_Identity=24.0860215053763, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI4827012, Length=264, Percent_Identity=31.8181818181818, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI40254478, Length=478, Percent_Identity=22.8033472803347, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI5032093, Length=406, Percent_Identity=25.615763546798, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI223468564, Length=281, Percent_Identity=27.7580071174377, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI223468566, Length=281, Percent_Identity=27.7580071174377, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI194239697, Length=288, Percent_Identity=26.7361111111111, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI301601644, Length=196, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI262359914, Length=384, Percent_Identity=23.4375, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1790514, Length=432, Percent_Identity=37.7314814814815, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI1789947, Length=383, Percent_Identity=39.1644908616188, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1788024, Length=415, Percent_Identity=26.9879518072289, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1789473, Length=388, Percent_Identity=23.4536082474227, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71996953, Length=442, Percent_Identity=26.4705882352941, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17537407, Length=438, Percent_Identity=26.9406392694064, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI193206505, Length=427, Percent_Identity=26.463700234192, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI193206654, Length=422, Percent_Identity=24.8815165876777, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71983099, Length=462, Percent_Identity=24.4588744588745, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71983106, Length=462, Percent_Identity=24.4588744588745, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17541374, Length=440, Percent_Identity=25.9090909090909, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24583025, Length=460, Percent_Identity=23.695652173913, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17137668, Length=460, Percent_Identity=23.695652173913, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24583023, Length=460, Percent_Identity=23.695652173913, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI281360481, Length=446, Percent_Identity=24.6636771300448, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281360483, Length=447, Percent_Identity=24.6085011185682, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17137666, Length=447, Percent_Identity=24.6085011185682, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 44982; Mature: 44982

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCCC
>Mature Secondary Structure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HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]