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The map label for this gene is polB [H]

Identifier: 238023676

GI number: 238023676

Start: 226266

End: 228638

Strand: Reverse

Name: polB [H]

Synonym: bglu_2g01980

Alternate gene names: 238023676

Gene position: 228638-226266 (Counterclockwise)

Preceding gene: 238023679

Following gene: 238023674

Centisome position: 8.09

GC content: 69.11

Gene sequence:

>2373_bases
TTGACTGATTTCGAGCAGGGTTTCATCCTGACCCGTCACTGGCGGGATACCGCAGCCGGCGTCGAAATCGAATTCTGGCT
CGCGACCGACGCAGGCGCGCGCCGCGTGCGCCTGCGCCCGCAGGAATCGGTCGCGTTCGTGCCGGCCACGCAGCGCGAGG
CCGCCGAGCGCGCGCTGGCGGGCGAGACCGGCGTCGAGCTGCGCCCGCTCGCGCTGCGCGATTTCCGCCGGCGCCCCGTG
GTCGGCCTCTATTGCCGCCGCCACCGTCATCTCTCGGCCCTGCACAAGCGCCTTGCGCAGGCCGGCGTCGACGTCTACGA
AGCCGACGTGAGCCCGCCCGACCGCTACACGATGGAGCGCTTCATCACCGCGCCGGTGCGCTTTCGCGGCCGGCCGGTGA
GCGCGGGCCTGCTGACCGACGGCGAACTCAAACCCGACGAGGCCTACCGCCCCGCGCTGCGCTGCGTCTCGCTCGACATC
GAGACGAGCGCGCGCGGCGAACTCTATTCGATCGCGCTGGAAGGCTGCGGCCGGCGCGACGTCTACATGCTCGGCCCGGC
CAACGGCGGCGCGCCCGACCCCAGCCTCACGCTGGTCTACTGCGAAAGCCGCGCCGAGCTGCTCGCGCAGCTCAACGACT
GGTTTACGCGCCACGACCCCGACGTGCTGATCGGCTGGAACCTGATCCAGTTCGACCTGCGCGTGCTGCACGCGCATTCG
CAGCAGTTCGGCGTGCCGCTTCGGCTCGGCCGCGACGGCAGCGTGCTCGACTGGCGCGCGCACGGCGCGCAGCCCGACCA
CTTCTTCGCCGGCGCGGCCGGGCGGCTCGTGATCGATGGCATCGACGCGCTGAAGTCGGCCACCTGGAGCTTCCCGTCGT
TCAGCCTCGAGTACGTGGCGCAAACGCTGCTCGGCGAGGGCAAGGCGGTCGACAATCCTTACCAGCGCATGGACGAGATC
CAGCGCCGCTTCGATCACGACAAGCCTGCACTCGCGCATTACAACCTGAAGGACTGCGAACTCGTCACGCGCATCTTCGC
GAAGGCGGACCTGCTGTCGTTCATGCTCGAACGTGCGACCGTCACCGGGCTGGCGGCCGATCGCACCGGCGGCTCGGTGG
CCGCCTTCACGCATCTCTATCTGCCGCGCATGCACCGGCTCGGCTACGTCGCGCCCAACCTCGGCGACGTGACGGGACAG
AACAGCCCCGGCGGCTTCGTGATGGATTCGCGTCCAGGGCTCTACGATTCGGTGCTGGTGCTCGACTACAAGAGCCTCTA
TCCCTCGATCATCCGCACCTTCCTGATCGACCCGGCCGGGCTCGTCGAGGGCCTCGACCGTCCCGACGACGCCCATTCGG
TCCCCGGCTTCCTCGGCGCGCGCTTCTCACGCACGCAGCACTGCCTGCCCGACATCGTGCGGCGCGTCTGGGAAAGCCGT
GAACTCGCCAAGCGCCAGCGCAACGCACCGCTCTCGCAGGCGCTGAAAATCATCATGAACGCGTTCTACGGCGTGCTCGG
CTCGTCGGGCTGCCGCTTCTTCGATCCGCGCCTGGCTTCGTCGATCACCATGCGCGGCCACGAGATCATGCACCGCACGC
GCGAGCTGATCGAGCAGCTCGGCCACGAAGTGATCTACGGCGACACCGATTCGACCTTCGTCTGGCTGCGCGAGCCGCAT
CGCGACGAGGACGCGGCCGCCAAGGGCCGCGCGATCGTCGAGCATGTGAACGGCTGGTGGCGCACGCACCTGCGCGAGCA
CTTCGGCCTCGAGAGCGCGCTCGAGCTGCAGTACGAGCGGCACTACCTGCGCTTCCTGATGCCGACCGTGCGCGGCGCCG
AGGAAGGCAGCAAGAAGCGCTACGCCGGCCTCGCGCGCGCGGCCGACGGCAGCGACGACGTGGTGTTCAAGGGCCTGGAG
ACGGTGCGCACCGACTGGACGCCGCTCGCGCAGCAGTTTCAGCGCGAACTCTATACCCGCGTGTTCCGCCGCGAACCCTA
TGGCGACTTCATCCGCGACACGGTGCGCAAGACGCTGGCCGGCGAACTCGACGCGCTGCTGGTGTACCGCAAGCGCGTGC
GCCGGCCGCTCAGCGAATACCAGCGCAACGTGCCGCCGCATGTGCGAGCGGCACGCACGGCCGACGCCTTCAACCGCGAG
CGGGGCCGCCCGCAGCAGTACCAGCGCGGCGGCTGGATCAGCTACGTGATGACCACGGCCGGCCCCGAGCCGCTGGAAAC
GATGCGCTCGCCGATCGACTATGCGTTCTACCTGAGCCGCCAGCTGCAGCCGGTGGCCGATGCGATCCTGCCGTTCCTGA
AGGACGATTTCGAATCGGTGGTGTCGGGGCAGGGCCGGCTGTTTCCGGCCTGA

Upstream 100 bases:

>100_bases
TGCGCCTGCCCGGCTGGCGGCACCGGCCGCGAATCGAGCGCAGCGCCCGCGCAGACGCTAAAATCCGCCGCCAGAGGCAT
TCCCACGGCGAGCACACGTT

Downstream 100 bases:

>100_bases
GCGCGGCGCCGTCGGCATCTGCTTCACGACCACGCACCAGCACGCCGAGGTGGGACGCGTTCGGAGCCGGCGCGGCGCGC
AAGGCCGCTCGCGGCGACGC

Product: DNA polymerase II

Products: NA

Alternate protein names: Pol II [H]

Number of amino acids: Translated: 790; Mature: 789

Protein sequence:

>790_residues
MTDFEQGFILTRHWRDTAAGVEIEFWLATDAGARRVRLRPQESVAFVPATQREAAERALAGETGVELRPLALRDFRRRPV
VGLYCRRHRHLSALHKRLAQAGVDVYEADVSPPDRYTMERFITAPVRFRGRPVSAGLLTDGELKPDEAYRPALRCVSLDI
ETSARGELYSIALEGCGRRDVYMLGPANGGAPDPSLTLVYCESRAELLAQLNDWFTRHDPDVLIGWNLIQFDLRVLHAHS
QQFGVPLRLGRDGSVLDWRAHGAQPDHFFAGAAGRLVIDGIDALKSATWSFPSFSLEYVAQTLLGEGKAVDNPYQRMDEI
QRRFDHDKPALAHYNLKDCELVTRIFAKADLLSFMLERATVTGLAADRTGGSVAAFTHLYLPRMHRLGYVAPNLGDVTGQ
NSPGGFVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPAGLVEGLDRPDDAHSVPGFLGARFSRTQHCLPDIVRRVWESR
ELAKRQRNAPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITMRGHEIMHRTRELIEQLGHEVIYGDTDSTFVWLREPH
RDEDAAAKGRAIVEHVNGWWRTHLREHFGLESALELQYERHYLRFLMPTVRGAEEGSKKRYAGLARAADGSDDVVFKGLE
TVRTDWTPLAQQFQRELYTRVFRREPYGDFIRDTVRKTLAGELDALLVYRKRVRRPLSEYQRNVPPHVRAARTADAFNRE
RGRPQQYQRGGWISYVMTTAGPEPLETMRSPIDYAFYLSRQLQPVADAILPFLKDDFESVVSGQGRLFPA

Sequences:

>Translated_790_residues
MTDFEQGFILTRHWRDTAAGVEIEFWLATDAGARRVRLRPQESVAFVPATQREAAERALAGETGVELRPLALRDFRRRPV
VGLYCRRHRHLSALHKRLAQAGVDVYEADVSPPDRYTMERFITAPVRFRGRPVSAGLLTDGELKPDEAYRPALRCVSLDI
ETSARGELYSIALEGCGRRDVYMLGPANGGAPDPSLTLVYCESRAELLAQLNDWFTRHDPDVLIGWNLIQFDLRVLHAHS
QQFGVPLRLGRDGSVLDWRAHGAQPDHFFAGAAGRLVIDGIDALKSATWSFPSFSLEYVAQTLLGEGKAVDNPYQRMDEI
QRRFDHDKPALAHYNLKDCELVTRIFAKADLLSFMLERATVTGLAADRTGGSVAAFTHLYLPRMHRLGYVAPNLGDVTGQ
NSPGGFVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPAGLVEGLDRPDDAHSVPGFLGARFSRTQHCLPDIVRRVWESR
ELAKRQRNAPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITMRGHEIMHRTRELIEQLGHEVIYGDTDSTFVWLREPH
RDEDAAAKGRAIVEHVNGWWRTHLREHFGLESALELQYERHYLRFLMPTVRGAEEGSKKRYAGLARAADGSDDVVFKGLE
TVRTDWTPLAQQFQRELYTRVFRREPYGDFIRDTVRKTLAGELDALLVYRKRVRRPLSEYQRNVPPHVRAARTADAFNRE
RGRPQQYQRGGWISYVMTTAGPEPLETMRSPIDYAFYLSRQLQPVADAILPFLKDDFESVVSGQGRLFPA
>Mature_789_residues
TDFEQGFILTRHWRDTAAGVEIEFWLATDAGARRVRLRPQESVAFVPATQREAAERALAGETGVELRPLALRDFRRRPVV
GLYCRRHRHLSALHKRLAQAGVDVYEADVSPPDRYTMERFITAPVRFRGRPVSAGLLTDGELKPDEAYRPALRCVSLDIE
TSARGELYSIALEGCGRRDVYMLGPANGGAPDPSLTLVYCESRAELLAQLNDWFTRHDPDVLIGWNLIQFDLRVLHAHSQ
QFGVPLRLGRDGSVLDWRAHGAQPDHFFAGAAGRLVIDGIDALKSATWSFPSFSLEYVAQTLLGEGKAVDNPYQRMDEIQ
RRFDHDKPALAHYNLKDCELVTRIFAKADLLSFMLERATVTGLAADRTGGSVAAFTHLYLPRMHRLGYVAPNLGDVTGQN
SPGGFVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPAGLVEGLDRPDDAHSVPGFLGARFSRTQHCLPDIVRRVWESRE
LAKRQRNAPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITMRGHEIMHRTRELIEQLGHEVIYGDTDSTFVWLREPHR
DEDAAAKGRAIVEHVNGWWRTHLREHFGLESALELQYERHYLRFLMPTVRGAEEGSKKRYAGLARAADGSDDVVFKGLET
VRTDWTPLAQQFQRELYTRVFRREPYGDFIRDTVRKTLAGELDALLVYRKRVRRPLSEYQRNVPPHVRAARTADAFNRER
GRPQQYQRGGWISYVMTTAGPEPLETMRSPIDYAFYLSRQLQPVADAILPFLKDDFESVVSGQGRLFPA

Specific function: Thought to be involved in DNA repair and/or mutagenesis [H]

COG id: COG0417

COG function: function code L; DNA polymerase elongation subunit (family B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-B family [H]

Homologues:

Organism=Homo sapiens, GI156616275, Length=702, Percent_Identity=27.6353276353276, Blast_Score=142, Evalue=2e-33,
Organism=Homo sapiens, GI106507301, Length=635, Percent_Identity=24.7244094488189, Blast_Score=128, Evalue=3e-29,
Organism=Escherichia coli, GI1786246, Length=784, Percent_Identity=66.0714285714286, Blast_Score=1062, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559488, Length=719, Percent_Identity=24.8956884561892, Blast_Score=135, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI32565317, Length=616, Percent_Identity=24.6753246753247, Blast_Score=121, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320101, Length=704, Percent_Identity=24.5738636363636, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6324227, Length=491, Percent_Identity=26.2729124236253, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24648780, Length=508, Percent_Identity=26.9685039370079, Blast_Score=127, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24664937, Length=671, Percent_Identity=24.8882265275708, Blast_Score=115, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006172
- InterPro:   IPR017964
- InterPro:   IPR006133
- InterPro:   IPR006134
- InterPro:   IPR023211
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 89446; Mature: 89314

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00116 DNA_POLYMERASE_B

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFEQGFILTRHWRDTAAGVEIEFWLATDAGARRVRLRPQESVAFVPATQREAAERALA
CCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCEEEECCCCCEEECCCHHHHHHHHHHC
GETGVELRPLALRDFRRRPVVGLYCRRHRHLSALHKRLAQAGVDVYEADVSPPDRYTMER
CCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHH
FITAPVRFRGRPVSAGLLTDGELKPDEAYRPALRCVSLDIETSARGELYSIALEGCGRRD
HHCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCEEEEEECCCCCCC
VYMLGPANGGAPDPSLTLVYCESRAELLAQLNDWFTRHDPDVLIGWNLIQFDLRVLHAHS
EEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHH
QQFGVPLRLGRDGSVLDWRAHGAQPDHFFAGAAGRLVIDGIDALKSATWSFPSFSLEYVA
HHCCCCEEECCCCCEEEEECCCCCCCCEECCCCCCEEEECHHHHHHCCCCCCCCHHHHHH
QTLLGEGKAVDNPYQRMDEIQRRFDHDKPALAHYNLKDCELVTRIFAKADLLSFMLERAT
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTGLAADRTGGSVAAFTHLYLPRMHRLGYVAPNLGDVTGQNSPGGFVMDSRPGLYDSVLV
HHCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHH
LDYKSLYPSIIRTFLIDPAGLVEGLDRPDDAHSVPGFLGARFSRTQHCLPDIVRRVWESR
HHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELAKRQRNAPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITMRGHEIMHRTRELIEQL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHC
GHEVIYGDTDSTFVWLREPHRDEDAAAKGRAIVEHVNGWWRTHLREHFGLESALELQYER
CCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HYLRFLMPTVRGAEEGSKKRYAGLARAADGSDDVVFKGLETVRTDWTPLAQQFQRELYTR
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
VFRREPYGDFIRDTVRKTLAGELDALLVYRKRVRRPLSEYQRNVPPHVRAARTADAFNRE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHC
RGRPQQYQRGGWISYVMTTAGPEPLETMRSPIDYAFYLSRQLQPVADAILPFLKDDFESV
CCCCHHHHCCCEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSGQGRLFPA
HCCCCCCCCC
>Mature Secondary Structure 
TDFEQGFILTRHWRDTAAGVEIEFWLATDAGARRVRLRPQESVAFVPATQREAAERALA
CCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCEEEECCCCCEEECCCHHHHHHHHHHC
GETGVELRPLALRDFRRRPVVGLYCRRHRHLSALHKRLAQAGVDVYEADVSPPDRYTMER
CCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHH
FITAPVRFRGRPVSAGLLTDGELKPDEAYRPALRCVSLDIETSARGELYSIALEGCGRRD
HHCCCHHCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCCEEEEEECCCCCCC
VYMLGPANGGAPDPSLTLVYCESRAELLAQLNDWFTRHDPDVLIGWNLIQFDLRVLHAHS
EEEEECCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHH
QQFGVPLRLGRDGSVLDWRAHGAQPDHFFAGAAGRLVIDGIDALKSATWSFPSFSLEYVA
HHCCCCEEECCCCCEEEEECCCCCCCCEECCCCCCEEEECHHHHHHCCCCCCCCHHHHHH
QTLLGEGKAVDNPYQRMDEIQRRFDHDKPALAHYNLKDCELVTRIFAKADLLSFMLERAT
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTGLAADRTGGSVAAFTHLYLPRMHRLGYVAPNLGDVTGQNSPGGFVMDSRPGLYDSVLV
HHCEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHH
LDYKSLYPSIIRTFLIDPAGLVEGLDRPDDAHSVPGFLGARFSRTQHCLPDIVRRVWESR
HHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELAKRQRNAPLSQALKIIMNAFYGVLGSSGCRFFDPRLASSITMRGHEIMHRTRELIEQL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHC
GHEVIYGDTDSTFVWLREPHRDEDAAAKGRAIVEHVNGWWRTHLREHFGLESALELQYER
CCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HYLRFLMPTVRGAEEGSKKRYAGLARAADGSDDVVFKGLETVRTDWTPLAQQFQRELYTR
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
VFRREPYGDFIRDTVRKTLAGELDALLVYRKRVRRPLSEYQRNVPPHVRAARTADAFNRE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHC
RGRPQQYQRGGWISYVMTTAGPEPLETMRSPIDYAFYLSRQLQPVADAILPFLKDDFESV
CCCCHHHHCCCEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSGQGRLFPA
HCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2034216; 2261080; 1630901; 9278503; 2217198; 9079692 [H]