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The map label for this gene is rutD [H]

Identifier: 238023611

GI number: 238023611

Start: 128353

End: 129162

Strand: Reverse

Name: rutD [H]

Synonym: bglu_2g01160

Alternate gene names: 238023611

Gene position: 129162-128353 (Counterclockwise)

Preceding gene: 238023644

Following gene: 238023608

Centisome position: 4.57

GC content: 60.12

Gene sequence:

>810_bases
ATGACAAAACTATCATTCAATGACCACGATCTTTATTACGCGGATGTCGGCAGCGGCCAGCCGATCATACTGATTCACGA
TTTAGGTAGCTGCGGTCTCGCATGGGCACGGCAAATGCCGTTTCTGCGTCAAGCGGGTTATCGCGTCATCGTGCCGGATC
TTCCCGGGCACGGTGCGTCTTCGTATCCGGACCGCACGCTCGACGTAAGGGAGCTTGCCGACGGCCTGCAGTTTCTCCTG
GATTACCTTGGCCTCGAAAGCGCCGCGCTCGTCGGCATCTCGCTTGGTGGAGCGATCGCGATGACGATCGCCATCGATGC
GCCGACACGCGTGGGCAAGCTGGTCGTCTGCAACGGCTTCTCGAACCTGGTCGCCGACGATTCGGTCCGCCGCTTCGAAC
TCTGGAAATCCGGTTTCCAGCGCGACGGTGACACGATCCGGTGGTTCGAGGAAATGTGGCCTTTGATGGTGAGCGCCGAA
TTCGCGCAATCGGAGGATGGTGAAATCGCGTATCAGATCGGCCACGCGCATGCGGCCACTACCGATGCCGCCCAGCTCGC
CCGCCTTTGCAACGGAATCGCGAACTACGACGTCAGAAGACGGCTGAACCTGATACGCAGCGAAACGCTGGTGTTGCAAA
GCGAAGATGGCAGCATTTTTCCGGCCGCCGAAGGGCAGCGGCTCAGGGTCATGATTCCGGGTGCCCGCTTCGAAACACTT
CCCGGGGGCGGACATCATGCAAATCTCGACCGCGCCGGGGCATTCAACTGGGCACTATTGCGCTTCCTGACCGGCCCCGT
CACTGCATAG

Upstream 100 bases:

>100_bases
CTCGCATTTGAAAGGGGCTCAGGTGCTCCACTTGTCGTCAATATATCTTAACATTAAGATAATCACGGGGCACACGTGGG
GGCAGCAATGGAGCGGGCAG

Downstream 100 bases:

>100_bases
TCATCCGTATCAATATCCGTGGAATCGTCGCCATGCAGGGATGGTCGCCACCGGCGCGGCCGGCGAACCATCCGGCTGCG
CGCCCGCAGTCATCGGCTTG

Product: alpha/beta hydrolase fold protein

Products: 3-oxoadipate

Alternate protein names: Aminohydrolase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTKLSFNDHDLYYADVGSGQPIILIHDLGSCGLAWARQMPFLRQAGYRVIVPDLPGHGASSYPDRTLDVRELADGLQFLL
DYLGLESAALVGISLGGAIAMTIAIDAPTRVGKLVVCNGFSNLVADDSVRRFELWKSGFQRDGDTIRWFEEMWPLMVSAE
FAQSEDGEIAYQIGHAHAATTDAAQLARLCNGIANYDVRRRLNLIRSETLVLQSEDGSIFPAAEGQRLRVMIPGARFETL
PGGGHHANLDRAGAFNWALLRFLTGPVTA

Sequences:

>Translated_269_residues
MTKLSFNDHDLYYADVGSGQPIILIHDLGSCGLAWARQMPFLRQAGYRVIVPDLPGHGASSYPDRTLDVRELADGLQFLL
DYLGLESAALVGISLGGAIAMTIAIDAPTRVGKLVVCNGFSNLVADDSVRRFELWKSGFQRDGDTIRWFEEMWPLMVSAE
FAQSEDGEIAYQIGHAHAATTDAAQLARLCNGIANYDVRRRLNLIRSETLVLQSEDGSIFPAAEGQRLRVMIPGARFETL
PGGGHHANLDRAGAFNWALLRFLTGPVTA
>Mature_268_residues
TKLSFNDHDLYYADVGSGQPIILIHDLGSCGLAWARQMPFLRQAGYRVIVPDLPGHGASSYPDRTLDVRELADGLQFLLD
YLGLESAALVGISLGGAIAMTIAIDAPTRVGKLVVCNGFSNLVADDSVRRFELWKSGFQRDGDTIRWFEEMWPLMVSAEF
AQSEDGEIAYQIGHAHAATTDAAQLARLCNGIANYDVRRRLNLIRSETLVLQSEDGSIFPAAEGQRLRVMIPGARFETLP
GGGHHANLDRAGAFNWALLRFLTGPVTA

Specific function: May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Hydrolase RutD family [H]

Homologues:

Organism=Homo sapiens, GI27597073, Length=110, Percent_Identity=33.6363636363636, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787244, Length=238, Percent_Identity=25.6302521008403, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR019913 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.1.1.24

Molecular weight: Translated: 29389; Mature: 29258

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLSFNDHDLYYADVGSGQPIILIHDLGSCGLAWARQMPFLRQAGYRVIVPDLPGHGAS
CCCCCCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHCCCHHHHCCCEEEECCCCCCCCC
SYPDRTLDVRELADGLQFLLDYLGLESAALVGISLGGAIAMTIAIDAPTRVGKLVVCNGF
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEEEECCCCCCCEEEEECCC
SNLVADDSVRRFELWKSGFQRDGDTIRWFEEMWPLMVSAEFAQSEDGEIAYQIGHAHAAT
CHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEHHHHCCCCCCEEEEECCCCCCC
TDAAQLARLCNGIANYDVRRRLNLIRSETLVLQSEDGSIFPAAEGQRLRVMIPGARFETL
HHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCCEEECCCCCEEEEEECCCCEECC
PGGGHHANLDRAGAFNWALLRFLTGPVTA
CCCCCCCCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKLSFNDHDLYYADVGSGQPIILIHDLGSCGLAWARQMPFLRQAGYRVIVPDLPGHGAS
CCCCCCCCEEEEEECCCCCCEEEEECCCCCHHHHHHCCCHHHHCCCEEEECCCCCCCCC
SYPDRTLDVRELADGLQFLLDYLGLESAALVGISLGGAIAMTIAIDAPTRVGKLVVCNGF
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEEEEECCCCCCCEEEEECCC
SNLVADDSVRRFELWKSGFQRDGDTIRWFEEMWPLMVSAEFAQSEDGEIAYQIGHAHAAT
CHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEHHHHCCCCCCEEEEECCCCCCC
TDAAQLARLCNGIANYDVRRRLNLIRSETLVLQSEDGSIFPAAEGQRLRVMIPGARFETL
HHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECCCCCEEECCCCCEEEEEECCCCEECC
PGGGHHANLDRAGAFNWALLRFLTGPVTA
CCCCCCCCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-oxoadipate enol-lactone; H2O

Specific reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA