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The map label for this gene is nhaR [H]

Identifier: 238023608

GI number: 238023608

Start: 122531

End: 123481

Strand: Reverse

Name: nhaR [H]

Synonym: bglu_2g01130

Alternate gene names: 238023608

Gene position: 123481-122531 (Counterclockwise)

Preceding gene: 238023611

Following gene: 238023606

Centisome position: 4.37

GC content: 62.57

Gene sequence:

>951_bases
ATGCGGATCGAACATCTGAACTTTCACCACCTCTTCTACTTCTGGCGCGTGGCTCGCACCGGCCATCTGACTCAGGCGGC
GGGCGAGCTTCACATTTCTCAATCGGCCCTCTCCGCCCAGATCAGACAGTTGGAAGACCGGCTGGGCGAGGCGTTGTTCG
AGCGCGAAAAGCGGCGTCTGATTTTGACGGACACCGGCCGAATGGTTTTCACGTATGCCGAAAACATCTTCGGCCTTGGG
CAGGAAATGCTGGGTAGGCTCCAGGGCCGCTCGGAAGGCATGGTTCGCTTGCGCGTGGGCAGCGTCGCCACGGTCTCACG
CAACTATCAGGAAAACTGGATTCGACCGCTTCTCAGTGATCCAGCCGTGACGCTCACGCTGGAATCGGGCACGCTCGACG
GACTCGTCGAGCGGCTCCGGCAGCATCAACTGGATATCGTGCTGGCCAATGAACCCCTGCCGTCGGACCCCGATCAACCG
CTCCATTGCAGTTTCCTGGGCAGTCAAGCCATCTCGCTGGTCGGGCCTGCGAGCACTTGGCATGGCCGCAGCCTGCGTGT
GCCCGACGACCTGGGCGGGCTCGATGTGGCGTTGCCCGGGCCGCGCCACGCCTTGCGCGCGCAGTTCGACGCGCTGTGCA
CGTCGGTTGGTGTAAAACCGCGCATCAGGGCGGAGGTCGACGATATGGCGATGCTGCGGCTCATAGCTCGGGACAGTGGC
TGGCTGACGGTGCTGCCCGAAGTGGTGGTACAAGACGAGTTGCGACAGGGCGTACTGGTCAGCGTGGGAGAAACGCCTGA
GCTTCAGGAGCACTTCTACGCGATTACGACGCCCCATCGGCATCGCATCGAACGCCTCGAAGAATTGTTTGCGGGCGCCA
CGCTTCCCGAGCCGAACCTGCTCGGCGCGATTTCATCGCCCAGGCACGCGCCTGTTTCGCCCAAGTCGTAA

Upstream 100 bases:

>100_bases
CATGGCGAACCTCTCGCAAAACAATGCGATAGATGATGTCCGACGCCAATTATTCTGTAAAATATATTTTATAGAACGAA
TACATTGATAAAAGAGAACG

Downstream 100 bases:

>100_bases
TATTGGTTGCATAAACAACGAATCAATACCATGGCCGCGCGGATGCAGTGGCGCCATTGCCGCCCGCTCCGGGCCCGGCC
GTACCCGCCTCTCTGCCGTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MRIEHLNFHHLFYFWRVARTGHLTQAAGELHISQSALSAQIRQLEDRLGEALFEREKRRLILTDTGRMVFTYAENIFGLG
QEMLGRLQGRSEGMVRLRVGSVATVSRNYQENWIRPLLSDPAVTLTLESGTLDGLVERLRQHQLDIVLANEPLPSDPDQP
LHCSFLGSQAISLVGPASTWHGRSLRVPDDLGGLDVALPGPRHALRAQFDALCTSVGVKPRIRAEVDDMAMLRLIARDSG
WLTVLPEVVVQDELRQGVLVSVGETPELQEHFYAITTPHRHRIERLEELFAGATLPEPNLLGAISSPRHAPVSPKS

Sequences:

>Translated_316_residues
MRIEHLNFHHLFYFWRVARTGHLTQAAGELHISQSALSAQIRQLEDRLGEALFEREKRRLILTDTGRMVFTYAENIFGLG
QEMLGRLQGRSEGMVRLRVGSVATVSRNYQENWIRPLLSDPAVTLTLESGTLDGLVERLRQHQLDIVLANEPLPSDPDQP
LHCSFLGSQAISLVGPASTWHGRSLRVPDDLGGLDVALPGPRHALRAQFDALCTSVGVKPRIRAEVDDMAMLRLIARDSG
WLTVLPEVVVQDELRQGVLVSVGETPELQEHFYAITTPHRHRIERLEELFAGATLPEPNLLGAISSPRHAPVSPKS
>Mature_316_residues
MRIEHLNFHHLFYFWRVARTGHLTQAAGELHISQSALSAQIRQLEDRLGEALFEREKRRLILTDTGRMVFTYAENIFGLG
QEMLGRLQGRSEGMVRLRVGSVATVSRNYQENWIRPLLSDPAVTLTLESGTLDGLVERLRQHQLDIVLANEPLPSDPDQP
LHCSFLGSQAISLVGPASTWHGRSLRVPDDLGGLDVALPGPRHALRAQFDALCTSVGVKPRIRAEVDDMAMLRLIARDSG
WLTVLPEVVVQDELRQGVLVSVGETPELQEHFYAITTPHRHRIERLEELFAGATLPEPNLLGAISSPRHAPVSPKS

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=279, Percent_Identity=27.2401433691756, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI157672245, Length=253, Percent_Identity=29.6442687747036, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=28.3400809716599, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790399, Length=290, Percent_Identity=25.8620689655172, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790262, Length=276, Percent_Identity=24.2753623188406, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787601, Length=264, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35247; Mature: 35247

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIEHLNFHHLFYFWRVARTGHLTQAAGELHISQSALSAQIRQLEDRLGEALFEREKRRL
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ILTDTGRMVFTYAENIFGLGQEMLGRLQGRSEGMVRLRVGSVATVSRNYQENWIRPLLSD
EEEECCCEEEEEHHHHHHCCHHHHHHHCCCCCCEEEEEECCEEEHHCCHHHHHHHHHHCC
PAVTLTLESGTLDGLVERLRQHQLDIVLANEPLPSDPDQPLHCSFLGSQAISLVGPASTW
CEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCHHHEEECCCCCC
HGRSLRVPDDLGGLDVALPGPRHALRAQFDALCTSVGVKPRIRAEVDDMAMLRLIARDSG
CCCEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHCCCC
WLTVLPEVVVQDELRQGVLVSVGETPELQEHFYAITTPHRHRIERLEELFAGATLPEPNL
CEEEHHHHHHHHHHCCCEEEEECCCCCHHHHEEEECCCHHHHHHHHHHHHCCCCCCCCCE
LGAISSPRHAPVSPKS
EECCCCCCCCCCCCCC
>Mature Secondary Structure
MRIEHLNFHHLFYFWRVARTGHLTQAAGELHISQSALSAQIRQLEDRLGEALFEREKRRL
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
ILTDTGRMVFTYAENIFGLGQEMLGRLQGRSEGMVRLRVGSVATVSRNYQENWIRPLLSD
EEEECCCEEEEEHHHHHHCCHHHHHHHCCCCCCEEEEEECCEEEHHCCHHHHHHHHHHCC
PAVTLTLESGTLDGLVERLRQHQLDIVLANEPLPSDPDQPLHCSFLGSQAISLVGPASTW
CEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCHHHEEECCCCCC
HGRSLRVPDDLGGLDVALPGPRHALRAQFDALCTSVGVKPRIRAEVDDMAMLRLIARDSG
CCCEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHCCCC
WLTVLPEVVVQDELRQGVLVSVGETPELQEHFYAITTPHRHRIERLEELFAGATLPEPNL
CEEEHHHHHHHHHHCCCEEEEECCCCCHHHHEEEECCCHHHHHHHHHHHHCCCCCCCCCE
LGAISSPRHAPVSPKS
EECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]