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The map label for this gene is lip2 [H]

Identifier: 238023549

GI number: 238023549

Start: 53191

End: 54231

Strand: Direct

Name: lip2 [H]

Synonym: bglu_2g00500

Alternate gene names: 238023549

Gene position: 53191-54231 (Clockwise)

Preceding gene: 238023548

Following gene: 238023551

Centisome position: 1.88

GC content: 68.49

Gene sequence:

>1041_bases
ATGAAGTTCGTCAAGCCGCTGCTGATCGCCGCCGTGTCGGCGTTTGCCACCGCCAGTTCCGCGTTCGCCGCCGGCGCGGC
CGCCTCGACTGTCGCGGACACGCCCGACGTCGCCACCACGCGCTTTCTCGCCGCGCTGAACGGCACGAAGGGGCCGGGCC
TCGAAACGCTGAGCCCGGCCAAGGCCCGGCAGGTGCTGGTGGATGCGCAGAACAGCGTGAAGGTGGACCTGTCGGGCATC
GACGTGTCGACGCGCACCATCGAGCAGGACGGCCTGAGCGTGCCGGTCACGATCGTGCGGCCGCAGGGCGTCAAGGGCAC
GCTGCCGGTGTTCATGTTCTTTCACGGCGGCGGCTGGATCCTCGGCGATTTCCCGACCCATGAGCGGCTGGTGCGCGACC
TCGTCGTGCAGTCGGGCGCGGTGGCGGTGTTCGTGAACTACACGCCGTCGCCGGAGGCGCATTATCCGGTGGCGATCAAC
CAGGCCTATGCGGCGACCCGTTGGGTGGCCGCGCACGGCGAGGAGATCGGCGTGGACGGCAGCCGCCTCGCGGTGGTCGG
CAACAGCGTGGGCGGCAACATGGCGGCCGTCGTCGCGCTGATGGCAAAGGACAAGGGCGGCCCGGCGATCCGTTTCCAGG
GCCTGCTCTGGCCGGTGACGGACCACAACTTCAACGACGGCTCGTATCAGGCGTATCAGAAAGACTACTTCCTGACGCGG
CCGATGATGAAGTGGTTCTGGGATGCCTACACGACCAGGCAAGCGCAGCGCAACGAGATCTACGCGTCGCCGCTGCGCGC
CTCGACGGCGGAGCTGAAGGGCCTGCCGCCGGCGCTGATCCAGGTCGCGCAGTTCGACGTGCTGCGTGACGAGGGCGAAG
CCTACGGCCGCAAGCTCGACGCGGCCGGCGTGGCGGTTGCCACGACGCGCTACGACGGCACGATCCACGACTTCGGGCTG
CTGAACGCGCTGGCCGAGGATGCCCCGACCAAGGCGGCGATGAAAGCCATGGCGAGCGAGCTGAAGTCGCGCCTGAATTG
A

Upstream 100 bases:

>100_bases
GACGCGCGGCAACATCGACGTCACGCTCACGATCGTCTGATCGCCCGGCCGCCATCCATTGCGTCATCCGCCATCGCCAT
TCATTGCTGAGGAATCCATC

Downstream 100 bases:

>100_bases
GCGGCAAGCCCGCGGCGCCGAGTTGCCCGGCGCCGGCGCGCGATTCGTGGCGCGGCACGGCCCAGCCCGGCTCGTTGGCC
CCTGCCACGGCCGAACCATG

Product: Esterase/lipase/thioesterase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MKFVKPLLIAAVSAFATASSAFAAGAAASTVADTPDVATTRFLAALNGTKGPGLETLSPAKARQVLVDAQNSVKVDLSGI
DVSTRTIEQDGLSVPVTIVRPQGVKGTLPVFMFFHGGGWILGDFPTHERLVRDLVVQSGAVAVFVNYTPSPEAHYPVAIN
QAYAATRWVAAHGEEIGVDGSRLAVVGNSVGGNMAAVVALMAKDKGGPAIRFQGLLWPVTDHNFNDGSYQAYQKDYFLTR
PMMKWFWDAYTTRQAQRNEIYASPLRASTAELKGLPPALIQVAQFDVLRDEGEAYGRKLDAAGVAVATTRYDGTIHDFGL
LNALAEDAPTKAAMKAMASELKSRLN

Sequences:

>Translated_346_residues
MKFVKPLLIAAVSAFATASSAFAAGAAASTVADTPDVATTRFLAALNGTKGPGLETLSPAKARQVLVDAQNSVKVDLSGI
DVSTRTIEQDGLSVPVTIVRPQGVKGTLPVFMFFHGGGWILGDFPTHERLVRDLVVQSGAVAVFVNYTPSPEAHYPVAIN
QAYAATRWVAAHGEEIGVDGSRLAVVGNSVGGNMAAVVALMAKDKGGPAIRFQGLLWPVTDHNFNDGSYQAYQKDYFLTR
PMMKWFWDAYTTRQAQRNEIYASPLRASTAELKGLPPALIQVAQFDVLRDEGEAYGRKLDAAGVAVATTRYDGTIHDFGL
LNALAEDAPTKAAMKAMASELKSRLN
>Mature_346_residues
MKFVKPLLIAAVSAFATASSAFAAGAAASTVADTPDVATTRFLAALNGTKGPGLETLSPAKARQVLVDAQNSVKVDLSGI
DVSTRTIEQDGLSVPVTIVRPQGVKGTLPVFMFFHGGGWILGDFPTHERLVRDLVVQSGAVAVFVNYTPSPEAHYPVAIN
QAYAATRWVAAHGEEIGVDGSRLAVVGNSVGGNMAAVVALMAKDKGGPAIRFQGLLWPVTDHNFNDGSYQAYQKDYFLTR
PMMKWFWDAYTTRQAQRNEIYASPLRASTAELKGLPPALIQVAQFDVLRDEGEAYGRKLDAAGVAVATTRYDGTIHDFGL
LNALAEDAPTKAAMKAMASELKSRLN

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI68299767, Length=267, Percent_Identity=26.2172284644195, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI21328446, Length=103, Percent_Identity=32.0388349514563, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI157041239, Length=165, Percent_Identity=28.4848484848485, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786682, Length=222, Percent_Identity=29.2792792792793, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17567059, Length=288, Percent_Identity=27.0833333333333, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71996133, Length=128, Percent_Identity=31.25, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 36871; Mature: 36871

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFVKPLLIAAVSAFATASSAFAAGAAASTVADTPDVATTRFLAALNGTKGPGLETLSPA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHH
KARQVLVDAQNSVKVDLSGIDVSTRTIEQDGLSVPVTIVRPQGVKGTLPVFMFFHGGGWI
HHHHEEEECCCCEEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCEEEEEEECCCEE
LGDFPTHERLVRDLVVQSGAVAVFVNYTPSPEAHYPVAINQAYAATRWVAAHGEEIGVDG
ECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECCHHHHHHHHHHCCCEECCCC
SRLAVVGNSVGGNMAAVVALMAKDKGGPAIRFQGLLWPVTDHNFNDGSYQAYQKDYFLTR
CEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
PMMKWFWDAYTTRQAQRNEIYASPLRASTAELKGLPPALIQVAQFDVLRDEGEAYGRKLD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCHHHHCCEEC
AAGVAVATTRYDGTIHDFGLLNALAEDAPTKAAMKAMASELKSRLN
CCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFVKPLLIAAVSAFATASSAFAAGAAASTVADTPDVATTRFLAALNGTKGPGLETLSPA
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHH
KARQVLVDAQNSVKVDLSGIDVSTRTIEQDGLSVPVTIVRPQGVKGTLPVFMFFHGGGWI
HHHHEEEECCCCEEEEEECCCCCCEEECCCCCEEEEEEECCCCCCCCCEEEEEEECCCEE
LGDFPTHERLVRDLVVQSGAVAVFVNYTPSPEAHYPVAINQAYAATRWVAAHGEEIGVDG
ECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECCHHHHHHHHHHCCCEECCCC
SRLAVVGNSVGGNMAAVVALMAKDKGGPAIRFQGLLWPVTDHNFNDGSYQAYQKDYFLTR
CEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHH
PMMKWFWDAYTTRQAQRNEIYASPLRASTAELKGLPPALIQVAQFDVLRDEGEAYGRKLD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCHHHHCCEEC
AAGVAVATTRYDGTIHDFGLLNALAEDAPTKAAMKAMASELKSRLN
CCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]