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The map label for this gene is yciC [H]

Identifier: 237814396

GI number: 237814396

Start: 4017716

End: 4019062

Strand: Reverse

Name: yciC [H]

Synonym: GBP346_A4194

Alternate gene names: 237814396

Gene position: 4019062-4017716 (Counterclockwise)

Preceding gene: 237814397

Following gene: 237814393

Centisome position: 98.06

GC content: 67.78

Gene sequence:

>1347_bases
ATGAACCAGCCGTTGCCCGTCACCGTGCTGTCCGGCTTCCTCGGCGCCGGCAAGACCACGCTGCTCAATCACATCCTCGC
GAATCGCGCGGGCCTGAAGGTCGCCGTGATCGTCAACGATCTCGCCGCGGCCAACGTCGACGCGACATTCGTGCGCGGCG
CGACCGAGCTGTCGCATATCGAAGCGCACCTCGTCGAGATGTCGAACGGCTGCATCTGCTGCACGCTGCGCGACGATCTG
CTCGTCGAGATCCGCCGCCTCGCGGCCGAAAACCGCTTCGACGCGATCGTGGTCGAATCGACGGGCATCGCCGAGCCGAT
GCCGATCGCCGAGACCTTCACGTTCGTCGACGACGACGGCTCCGCGCTCGAGGACGTCGCGCGTCTCGATACGATGGTCA
CCGTCATCGACGCGTTCAACTTCCTGCACGACTATGCGCGCGACGACGCGCTCGCGGAGCACGGCCTCGCGGCGACCGAC
GAAGACGACCGCACGCTCGTCGAGCTGCTGATCGAGCAGATCGAGTTTTGCGACGTGCTCGTGATCAACAAGGCGGATCT
CGTCGACGCCGACGCGCTCGCGCGCCTGCAGCGGATCCTCGCGAACCTGAATCCGCGCGCGCGGCAGATCGTGAGCCGCT
TCGGCGACGTGCCGCTCGCCGAAGTGATCAATACCGGCCGCTTCGATTTCGACGCGGCCGCGAACGCGCCGGGCTGGCTC
GCGTCGCTCGAGCATCGGCACGACGCCGATGAAGCCGAGTGCGGACAAGGCCAAAGCCAAGGCGACGGCCGCGTGCACAG
CGAGGCCGACGAATACGGCATCGGCCACTTCGTCTATCGCGCGCGCCGGCCGTTCCATCCGCAGCGGCTCTGGGCGCTCC
TGCACGAAGAGTGGAAGGGCGTGCTGCGCAGCAAGGGGTTTTTCTGGCTCGCGACGCGCAACGACATCGCGGGTTCGCTG
TCGCAGGCGGGCGGCGTGTGCCGGCACGGTCCGGCCGGCCACTGGTGGGCGGCGCAGGATCGCACCGAATGGCCGGAGGC
GGGCGACGAGCTGTACGACGAGATCGTCGCCGACTGGCACGGCGAGCTCGCCGACACGTCGATCGGCGATCGGCGCCAGG
AGCTCGTACTGATCGGCATCGGGCTCGATGCGGCGGCGTGGCGCGCGAAGTTCGACGCGTGCCTGCTCACCGGCGCGGAG
TACGCGCAAGGCAAGCAGGCGTGGGCGGGCTACGCGGATCCGTTCCCGGCATGGGACGTCGATGATCACGATCACGATCA
CGACCATGCGCATGACCACCATGATCACGACCACGGCGACGACTCGGAAATCGTCCACCGCCACTGA

Upstream 100 bases:

>100_bases
CGGCTTTCCCGCCGTCCGTTCGCGCCGGCCCGCGCCGGTGCCGCCCCGTTTTCGGGGTGCGGCGGCTCGCTTCCCGCTTC
TTTCGTTGGTGCGCACCGCA

Downstream 100 bases:

>100_bases
TCGTCAAAGATTGAAAAAGACGATGCGGCGTGGCAAAAAAACCTCGTCGAAAAGAAAAACCCGCTGAAACCAGCGGGTTT
TTTGTTCGCGAACAGCTCGT

Product: CobW/P47K family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MNQPLPVTVLSGFLGAGKTTLLNHILANRAGLKVAVIVNDLAAANVDATFVRGATELSHIEAHLVEMSNGCICCTLRDDL
LVEIRRLAAENRFDAIVVESTGIAEPMPIAETFTFVDDDGSALEDVARLDTMVTVIDAFNFLHDYARDDALAEHGLAATD
EDDRTLVELLIEQIEFCDVLVINKADLVDADALARLQRILANLNPRARQIVSRFGDVPLAEVINTGRFDFDAAANAPGWL
ASLEHRHDADEAECGQGQSQGDGRVHSEADEYGIGHFVYRARRPFHPQRLWALLHEEWKGVLRSKGFFWLATRNDIAGSL
SQAGGVCRHGPAGHWWAAQDRTEWPEAGDELYDEIVADWHGELADTSIGDRRQELVLIGIGLDAAAWRAKFDACLLTGAE
YAQGKQAWAGYADPFPAWDVDDHDHDHDHAHDHHDHDHGDDSEIVHRH

Sequences:

>Translated_448_residues
MNQPLPVTVLSGFLGAGKTTLLNHILANRAGLKVAVIVNDLAAANVDATFVRGATELSHIEAHLVEMSNGCICCTLRDDL
LVEIRRLAAENRFDAIVVESTGIAEPMPIAETFTFVDDDGSALEDVARLDTMVTVIDAFNFLHDYARDDALAEHGLAATD
EDDRTLVELLIEQIEFCDVLVINKADLVDADALARLQRILANLNPRARQIVSRFGDVPLAEVINTGRFDFDAAANAPGWL
ASLEHRHDADEAECGQGQSQGDGRVHSEADEYGIGHFVYRARRPFHPQRLWALLHEEWKGVLRSKGFFWLATRNDIAGSL
SQAGGVCRHGPAGHWWAAQDRTEWPEAGDELYDEIVADWHGELADTSIGDRRQELVLIGIGLDAAAWRAKFDACLLTGAE
YAQGKQAWAGYADPFPAWDVDDHDHDHDHAHDHHDHDHGDDSEIVHRH
>Mature_448_residues
MNQPLPVTVLSGFLGAGKTTLLNHILANRAGLKVAVIVNDLAAANVDATFVRGATELSHIEAHLVEMSNGCICCTLRDDL
LVEIRRLAAENRFDAIVVESTGIAEPMPIAETFTFVDDDGSALEDVARLDTMVTVIDAFNFLHDYARDDALAEHGLAATD
EDDRTLVELLIEQIEFCDVLVINKADLVDADALARLQRILANLNPRARQIVSRFGDVPLAEVINTGRFDFDAAANAPGWL
ASLEHRHDADEAECGQGQSQGDGRVHSEADEYGIGHFVYRARRPFHPQRLWALLHEEWKGVLRSKGFFWLATRNDIAGSL
SQAGGVCRHGPAGHWWAAQDRTEWPEAGDELYDEIVADWHGELADTSIGDRRQELVLIGIGLDAAAWRAKFDACLLTGAE
YAQGKQAWAGYADPFPAWDVDDHDHDHDHAHDHHDHDHGDDSEIVHRH

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI146231952, Length=227, Percent_Identity=29.9559471365639, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI148727351, Length=227, Percent_Identity=29.5154185022026, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI126722884, Length=227, Percent_Identity=29.5154185022026, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI33469141, Length=227, Percent_Identity=29.0748898678414, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI223941779, Length=202, Percent_Identity=30.6930693069307, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI223941776, Length=217, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI119120938, Length=135, Percent_Identity=34.0740740740741, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI87082430, Length=234, Percent_Identity=31.6239316239316, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788499, Length=193, Percent_Identity=25.9067357512953, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324356, Length=235, Percent_Identity=26.8085106382979, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 49445; Mature: 49445

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPLPVTVLSGFLGAGKTTLLNHILANRAGLKVAVIVNDLAAANVDATFVRGATELSHI
CCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEEHHHHCCCCHHHHHCHHHHHHH
EAHLVEMSNGCICCTLRDDLLVEIRRLAAENRFDAIVVESTGIAEPMPIAETFTFVDDDG
HHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHEEEEECCCC
SALEDVARLDTMVTVIDAFNFLHDYARDDALAEHGLAATDEDDRTLVELLIEQIEFCDVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEE
VINKADLVDADALARLQRILANLNPRARQIVSRFGDVPLAEVINTGRFDFDAAANAPGWL
EECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHH
ASLEHRHDADEAECGQGQSQGDGRVHSEADEYGIGHFVYRARRPFHPQRLWALLHEEWKG
HHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
VLRSKGFFWLATRNDIAGSLSQAGGVCRHGPAGHWWAAQDRTEWPEAGDELYDEIVADWH
HHHCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GELADTSIGDRRQELVLIGIGLDAAAWRAKFDACLLTGAEYAQGKQAWAGYADPFPAWDV
CCHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHCCCHHHCCCCCCCCCCCC
DDHDHDHDHAHDHHDHDHGDDSEIVHRH
CCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNQPLPVTVLSGFLGAGKTTLLNHILANRAGLKVAVIVNDLAAANVDATFVRGATELSHI
CCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEEHHHHCCCCHHHHHCHHHHHHH
EAHLVEMSNGCICCTLRDDLLVEIRRLAAENRFDAIVVESTGIAEPMPIAETFTFVDDDG
HHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHEEEEECCCC
SALEDVARLDTMVTVIDAFNFLHDYARDDALAEHGLAATDEDDRTLVELLIEQIEFCDVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCEE
VINKADLVDADALARLQRILANLNPRARQIVSRFGDVPLAEVINTGRFDFDAAANAPGWL
EECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHH
ASLEHRHDADEAECGQGQSQGDGRVHSEADEYGIGHFVYRARRPFHPQRLWALLHEEWKG
HHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
VLRSKGFFWLATRNDIAGSLSQAGGVCRHGPAGHWWAAQDRTEWPEAGDELYDEIVADWH
HHHCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GELADTSIGDRRQELVLIGIGLDAAAWRAKFDACLLTGAEYAQGKQAWAGYADPFPAWDV
CCHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHCCCHHHCCCCCCCCCCCC
DDHDHDHDHAHDHHDHDHGDDSEIVHRH
CCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]