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The map label for this gene is putA [H]

Identifier: 237814334

GI number: 237814334

Start: 3958871

End: 3962800

Strand: Reverse

Name: putA [H]

Synonym: GBP346_A4132

Alternate gene names: 237814334

Gene position: 3962800-3958871 (Counterclockwise)

Preceding gene: 237814337

Following gene: 237814333

Centisome position: 96.69

GC content: 70.18

Gene sequence:

>3930_bases
ATGGCAAGCACCACACTGGGCGTCAAAGTCGACGATCTGCTGCGCGCGCGTCTGAAGGACGCGGCGTCGCGGCTCGAGCG
CACTCCTCACTGGCTGATCAAGCAGGCGATCTTCGCGTATCTCGAGCGGATCGAGCATGGTCAGCTTCCGCCGGAGCTCT
CCGGCCACACGGGCGTCGCCGATCTGTCCGACAGCCACGCCGACGGCGACGACGACGGCGCGCCGCACCCGTTCCTCGAA
TTCGCGCAGAGCGTGCAGCCGCAGTCGGTGCTGCGCGCGGCGATCACGGCCGCGTACCGGCGGCCGGAGCCCGAATGCGT
GCCGTTCCTGATCGGCGAGGCGCGGCTGCCCGCGAGCCTCGCGTCGGACGTGCAGGCAATGGCGGCGGGCCTTGTCGAGG
CGCTGCGCGAGAAGAGCTCGGGCGGCGGCGTCGAGGGGCTGATCCATGAATTCTCGCTGTCGAGCCAGGAGGGCGTCGCG
CTGATGTGCCTCGCCGAGGCGCTGCTGCGGATTCCCGATCGCGCGACGCGCGACGCGCTGATTCGCGACAAGATCAGCAA
GGGCGACTGGCGCTCGCACGTCGGCCACGCGCCGTCGCTGTTCGTCAACGCGGCCACCTGGGGCCTGATGATCACCGGCA
AGCTCGTCACGACGAACAGCGAGGCGGGCCTGTCGTCGGCGCTCACGCGGCTGATCGGCAAGGGCGGCGAGCCGTTGATC
CGAAAGGGCGTCGACATGGCGATGCGCCTGATGGGCGAGCAGTTCGTCACGGGCGAGACGATCTCCGAAGCGCTCGCGAA
CAGCCGCAAGTACGAGGCGCGCGGCTTCCGTTACTCGTACGACATGCTCGGCGAAGCGGCGACCACCGAAGAGGACGCGC
TGCGCTACTACGCGTCGTACGAGCAGGCGATCCACGCGATCGGCAAGGCGGCGGGCGGCCGCGGCATCTACGAGGGCCCG
GGCATCTCGATCAAGCTCTCGGCGCTGCATGCGCGCTACTCGCGCTCCCAGCAGGAACGCACGATGAACGAGCTGCTGCC
GCGCGTGCGCTCGCTCGCGCTGCTCGCGCGCCGCTATGACATCGGCCTGAACATCGACGCCGAGGAGGCGGACCGGCTCG
AGCTCTCGCTCGATCTGCTCGAGGCGCTGTGCTTCGATCCGGAGCTCGCCGGCTGGAACGGCATCGGCTTCGTCGTGCAG
GCGTACCAGAAGCGCTGCCCGTTCGTGATCGACTACCTTGTCGACCTCGCGCGCCGCAGCCGCCATCGCCTGATGATCCG
CCTCGTGAAGGGCGCGTACTGGGATTCCGAGATCAAGCGCGCGCAGGTGGACGGCCTCGAAGGCTATCCGGTCTATACGC
GCAAGATCTACACCGACGTGTCCTACCTCGCGTGCGCGAAGAAGCTGCTCGCCGCGCCGGACGCCGTGTATCCGCAGTTC
GCGACGCACAACGCGTACACGCTCGCCGCGATCTATCACCTCGCGGGCCAGAACTACTACCCCGGCCAGTACGAGTTCCA
GTGCCTGCACGGGATGGGCGAGCCGCTGTACGAGGAAGTCACCGGCCGCGACAAGCTGAACCGCCCATGCCGCGTGTACG
CGCCCGTCGGCACGCACGAGACGCTGCTTGCGTATCTCGTGCGCCGCCTGCTGGAAAACGGCGCGAACACGTCGTTCGTG
AACCGGATCGCCGACAAGACCGTGTCGGTGAAGGAACTGGTGGCCGATCCGGTCGAGGATGCGCTGAAGGTCGTGCCGCT
CGGCGCGCCGCACGCGAAGATTGCGCTGCCGCGCGAGCTGTACGGTGCGTCGCGCGTCAATTCGATGGGCCTCGATCTGT
CGAACGAGCACCGGCTCGCGTCGCTGTCGTCGGCGCTGCTCGCGAGCGCGCATCATCCGTGGCGCGCCGCGCCGATGCTC
GCCGACGACGCGCTCGCCCACGCCGCGCCGCGCGACGTGCGCAATCCGGCCGATCTGCGCGACGTCGTCGGCACGGTGAG
CGAAGCGACGCCCGACGAGGTGAGCGCGGCGCTCGCGCACGCGGTCGCGGCCGCGCCGATCTGGCAGGCGACGCCCGTCG
ACGCGCGCGCGGACTGCCTCGCGCGCGCGGCGGACCTGCTCGAAGCGCAGATGCACACGCTGATGGGCCTGATCGTGCGC
GAGGCGGGCAAATCGCTGCCGAACGCGATCGCCGAGATCCGCGAAGCGGTCGACTTCCTGCGCTACTACTCGGCGCAGAT
CCGCGATGAATTCTCGAACGACACGCACCGCCCGCTCGGCCCCGTCGTCTGCATCAGCCCGTGGAACTTCCCGCTCGCGA
TCTTCATGGGCCAGGTCGCAGCCGCCCTGGCGGCGGGCAACACGGTGCTCGCGAAGCCGGCCGAGCAGACGCCGCTGATC
GCCGCGCAGGCGGTGCGCCTGCTGCGCGACGCCGGCGTGCCGGCGGGCGCGGTGCAACTGCTGCCGGGCAACGGCGAGAC
GGTGGGCGCGGCGCTCGTGGCGGACCCCCGCACGCGCGCGGTGATGTTCACCGGCTCGACCGAAGTCGCGCGCCTCATCA
ACAAGACGCTGTCGTCGCGCCTCGATCCGGACGGCAGGCCGATCCCGCTGATCGCCGAGACGGGCGGCCAGAACGCGATG
ATCGTCGATTCGTCGGCGCTCGCCGAGCAGGTGGTCGCCGACGTGCTGCAGTCGTCGTTCGACTCGGCCGGTCAACGCTG
TTCGGCGCTGCGCGTTCTGTGTCTACAGGACGACGTCGCGGATCGCACGCTGACGATGCTCAAGGGCGCGATGCGCGAGC
TCGCGCTCGGCAATCCGGACCGGCTGTCGGTGGACGTCGGCCCGGTGATCGACGCCGACGCGAAGCGCACGATCGACACG
CACATCGCGGCGATGAAGGACAAGGGGCACGCGGTCACGCAGCTCGAGATGCCGGACGCATGCGCGCAGGGCACGTTCGT
GCCGCCGACGATCATCGAGATCGGCAACGTCGACGAGCTCAAGCGTGAAGTGTTCGGCCCGGTGCTGCACGTCGTGCGTT
ATCGCCGCAGCGGCCTCGACAAGCTGCTCGAGCAGATCCGCGCGACGGGCTATGGGCTCACGCTCGGCATTCACACGCGG
ATCGACGAGACGATCGCGCACGTGATCTCGCGCGCGCACGTCGGCAACATCTACGTGAACCGCAACGTGATCGGCGCGGT
GGTGGGCGTGCAGCCGTTCGGCGGCGAAGGGCTGTCGGGCACGGGGCCGAAGGCGGGCGGCGCGCTCTACTTGCAGCGCC
TGCTCGCGACGCGCCCGGCCGGGCTGCCGCGCTCGCTCGAGGCGGCGCTCGTCGCCGATGCGCCGCAGGAAGGCGAGACG
CGCGATAATCCATCCGCTGCGCTCACCGCGCTGCGCGACTGGTTGATCGAGCAGCGCGAGCCGGCGCTCGCCGCGCGCTG
CGACGGCTATCTGTCGCACGTGCTCGCGGGCGCAACCGCCGTGCTTTCAGGGCCGACGGGCGAGCGCAATACGTATACAC
TCGGCGCGCGCGGCACGGTGCTGTGCATCGCGGCGACGGCAAGCGGCGCGCGCGCGCAGTTCGCGGCGGCGCTCGCCACC
GGCAACCGCGCGCTTTTCGCGGGCGCGGCGGGCGAGGCGCTCGCCGCGGCGCTGCCGGCGCAACTGAAGGCGCACGCGGG
CGTGAGAAAGCAGGCGGACGCGGCGTTCGACGCGGTGCTGTTCGAAGGCGACAGCGACGAGTTGCTCGCGCTCGTGAAGG
AAGTCGCGCAGCGCCCGGGGCCGATCGTGTCGGTGCAGGGCGTCGCGGCGGGCGCGTTCGAGAACGGCGGCGACGAAGAC
TACGCGCTCGAGCGGCTCCTCACCGAGCGCTCGGTGAGCGTGAACACCGCGGCGGCAGGCGGCAATGCGAATTTGATGAC
GATTGGCTGA

Upstream 100 bases:

>100_bases
CCGGGTGTGAAATCTGGTTGCACCTTTTTATTGCCTGCCTTACGATTTTGCGATCTTTTAAAGTCCTTGGCCGGCATCGG
GCCGGCACTAGAAGAAAATC

Downstream 100 bases:

>100_bases
GCAATCCTTGCCCTTCGATTCAAGAAACGGAAGCGGCAAGGCGAACCCGAAGTCGCTCCATTTACCCTGGTACTAGGAGA
AGATATGCAACACACGATGA

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1309; Mature: 1308

Protein sequence:

>1309_residues
MASTTLGVKVDDLLRARLKDAASRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHTGVADLSDSHADGDDDGAPHPFLE
FAQSVQPQSVLRAAITAAYRRPEPECVPFLIGEARLPASLASDVQAMAAGLVEALREKSSGGGVEGLIHEFSLSSQEGVA
LMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGKGGEPLI
RKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDALRYYASYEQAIHAIGKAAGGRGIYEGP
GISIKLSALHARYSRSQQERTMNELLPRVRSLALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPELAGWNGIGFVVQ
AYQKRCPFVIDYLVDLARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQF
ATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFV
NRIADKTVSVKELVADPVEDALKVVPLGAPHAKIALPRELYGASRVNSMGLDLSNEHRLASLSSALLASAHHPWRAAPML
ADDALAHAAPRDVRNPADLRDVVGTVSEATPDEVSAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLIVR
EAGKSLPNAIAEIREAVDFLRYYSAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLI
AAQAVRLLRDAGVPAGAVQLLPGNGETVGAALVADPRTRAVMFTGSTEVARLINKTLSSRLDPDGRPIPLIAETGGQNAM
IVDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMRELALGNPDRLSVDVGPVIDADAKRTIDT
HIAAMKDKGHAVTQLEMPDACAQGTFVPPTIIEIGNVDELKREVFGPVLHVVRYRRSGLDKLLEQIRATGYGLTLGIHTR
IDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPRSLEAALVADAPQEGET
RDNPSAALTALRDWLIEQREPALAARCDGYLSHVLAGATAVLSGPTGERNTYTLGARGTVLCIAATASGARAQFAAALAT
GNRALFAGAAGEALAAALPAQLKAHAGVRKQADAAFDAVLFEGDSDELLALVKEVAQRPGPIVSVQGVAAGAFENGGDED
YALERLLTERSVSVNTAAAGGNANLMTIG

Sequences:

>Translated_1309_residues
MASTTLGVKVDDLLRARLKDAASRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHTGVADLSDSHADGDDDGAPHPFLE
FAQSVQPQSVLRAAITAAYRRPEPECVPFLIGEARLPASLASDVQAMAAGLVEALREKSSGGGVEGLIHEFSLSSQEGVA
LMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGKGGEPLI
RKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDALRYYASYEQAIHAIGKAAGGRGIYEGP
GISIKLSALHARYSRSQQERTMNELLPRVRSLALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPELAGWNGIGFVVQ
AYQKRCPFVIDYLVDLARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQF
ATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFV
NRIADKTVSVKELVADPVEDALKVVPLGAPHAKIALPRELYGASRVNSMGLDLSNEHRLASLSSALLASAHHPWRAAPML
ADDALAHAAPRDVRNPADLRDVVGTVSEATPDEVSAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLIVR
EAGKSLPNAIAEIREAVDFLRYYSAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLI
AAQAVRLLRDAGVPAGAVQLLPGNGETVGAALVADPRTRAVMFTGSTEVARLINKTLSSRLDPDGRPIPLIAETGGQNAM
IVDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMRELALGNPDRLSVDVGPVIDADAKRTIDT
HIAAMKDKGHAVTQLEMPDACAQGTFVPPTIIEIGNVDELKREVFGPVLHVVRYRRSGLDKLLEQIRATGYGLTLGIHTR
IDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPRSLEAALVADAPQEGET
RDNPSAALTALRDWLIEQREPALAARCDGYLSHVLAGATAVLSGPTGERNTYTLGARGTVLCIAATASGARAQFAAALAT
GNRALFAGAAGEALAAALPAQLKAHAGVRKQADAAFDAVLFEGDSDELLALVKEVAQRPGPIVSVQGVAAGAFENGGDED
YALERLLTERSVSVNTAAAGGNANLMTIG
>Mature_1308_residues
ASTTLGVKVDDLLRARLKDAASRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHTGVADLSDSHADGDDDGAPHPFLEF
AQSVQPQSVLRAAITAAYRRPEPECVPFLIGEARLPASLASDVQAMAAGLVEALREKSSGGGVEGLIHEFSLSSQEGVAL
MCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGKGGEPLIR
KGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDALRYYASYEQAIHAIGKAAGGRGIYEGPG
ISIKLSALHARYSRSQQERTMNELLPRVRSLALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPELAGWNGIGFVVQA
YQKRCPFVIDYLVDLARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQFA
THNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFVN
RIADKTVSVKELVADPVEDALKVVPLGAPHAKIALPRELYGASRVNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLA
DDALAHAAPRDVRNPADLRDVVGTVSEATPDEVSAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLIVRE
AGKSLPNAIAEIREAVDFLRYYSAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLIA
AQAVRLLRDAGVPAGAVQLLPGNGETVGAALVADPRTRAVMFTGSTEVARLINKTLSSRLDPDGRPIPLIAETGGQNAMI
VDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMRELALGNPDRLSVDVGPVIDADAKRTIDTH
IAAMKDKGHAVTQLEMPDACAQGTFVPPTIIEIGNVDELKREVFGPVLHVVRYRRSGLDKLLEQIRATGYGLTLGIHTRI
DETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPRSLEAALVADAPQEGETR
DNPSAALTALRDWLIEQREPALAARCDGYLSHVLAGATAVLSGPTGERNTYTLGARGTVLCIAATASGARAQFAAALATG
NRALFAGAAGEALAAALPAQLKAHAGVRKQADAAFDAVLFEGDSDELLALVKEVAQRPGPIVSVQGVAAGAFENGGDEDY
ALERLLTERSVSVNTAAAGGNANLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=454, Percent_Identity=31.7180616740088, Blast_Score=180, Evalue=9e-45,
Organism=Homo sapiens, GI153266822, Length=456, Percent_Identity=30.0438596491228, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI25777732, Length=447, Percent_Identity=30.4250559284116, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI25777724, Length=453, Percent_Identity=28.9183222958057, Blast_Score=164, Evalue=5e-40,
Organism=Homo sapiens, GI25777730, Length=450, Percent_Identity=29.3333333333333, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI25777736, Length=445, Percent_Identity=30.1123595505618, Blast_Score=161, Evalue=4e-39,
Organism=Homo sapiens, GI25777734, Length=445, Percent_Identity=30.1123595505618, Blast_Score=161, Evalue=4e-39,
Organism=Homo sapiens, GI238859541, Length=450, Percent_Identity=29.7777777777778, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI12007648, Length=444, Percent_Identity=29.0540540540541, Blast_Score=158, Evalue=4e-38,
Organism=Homo sapiens, GI25777728, Length=408, Percent_Identity=29.4117647058824, Blast_Score=157, Evalue=7e-38,
Organism=Homo sapiens, GI21614513, Length=426, Percent_Identity=29.3427230046948, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI4507229, Length=496, Percent_Identity=28.8306451612903, Blast_Score=148, Evalue=4e-35,
Organism=Homo sapiens, GI238814322, Length=440, Percent_Identity=27.5, Blast_Score=147, Evalue=1e-34,
Organism=Homo sapiens, GI11095441, Length=426, Percent_Identity=28.6384976525822, Blast_Score=140, Evalue=6e-33,
Organism=Homo sapiens, GI25777721, Length=509, Percent_Identity=27.8978388998035, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI188035924, Length=463, Percent_Identity=27.4298056155508, Blast_Score=137, Evalue=7e-32,
Organism=Homo sapiens, GI310128103, Length=463, Percent_Identity=27.4298056155508, Blast_Score=137, Evalue=8e-32,
Organism=Homo sapiens, GI310128093, Length=461, Percent_Identity=27.114967462039, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI115387104, Length=443, Percent_Identity=25.5079006772009, Blast_Score=131, Evalue=6e-30,
Organism=Homo sapiens, GI25952152, Length=438, Percent_Identity=27.8538812785388, Blast_Score=130, Evalue=1e-29,
Organism=Homo sapiens, GI310128091, Length=396, Percent_Identity=28.5353535353535, Blast_Score=121, Evalue=5e-27,
Organism=Homo sapiens, GI25777726, Length=452, Percent_Identity=25.2212389380531, Blast_Score=114, Evalue=6e-25,
Organism=Homo sapiens, GI310128087, Length=276, Percent_Identity=29.3478260869565, Blast_Score=100, Evalue=1e-20,
Organism=Homo sapiens, GI206597441, Length=436, Percent_Identity=25, Blast_Score=98, Evalue=5e-20,
Organism=Homo sapiens, GI206597439, Length=436, Percent_Identity=25, Blast_Score=98, Evalue=5e-20,
Organism=Homo sapiens, GI22907049, Length=436, Percent_Identity=25, Blast_Score=98, Evalue=5e-20,
Organism=Homo sapiens, GI71773324, Length=433, Percent_Identity=24.7113163972286, Blast_Score=95, Evalue=5e-19,
Organism=Homo sapiens, GI310128089, Length=336, Percent_Identity=27.3809523809524, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI4502043, Length=390, Percent_Identity=24.6153846153846, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI238814371, Length=390, Percent_Identity=24.6153846153846, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI310128095, Length=322, Percent_Identity=27.3291925465839, Blast_Score=88, Evalue=7e-17,
Organism=Homo sapiens, GI301500698, Length=432, Percent_Identity=24.537037037037, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI310128101, Length=223, Percent_Identity=27.8026905829596, Blast_Score=81, Evalue=7e-15,
Organism=Homo sapiens, GI310128099, Length=222, Percent_Identity=27.9279279279279, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI73695881, Length=336, Percent_Identity=23.8095238095238, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI73695879, Length=336, Percent_Identity=23.8095238095238, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI310128097, Length=269, Percent_Identity=27.5092936802974, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI4557303, Length=336, Percent_Identity=22.9166666666667, Blast_Score=78, Evalue=6e-14,
Organism=Homo sapiens, GI73466520, Length=336, Percent_Identity=22.9166666666667, Blast_Score=77, Evalue=1e-13,
Organism=Escherichia coli, GI1787250, Length=1331, Percent_Identity=66.0405709992487, Blast_Score=1710, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=457, Percent_Identity=31.2910284463895, Blast_Score=184, Evalue=3e-47,
Organism=Escherichia coli, GI1787715, Length=447, Percent_Identity=31.9910514541387, Blast_Score=163, Evalue=8e-41,
Organism=Escherichia coli, GI1788042, Length=456, Percent_Identity=31.359649122807, Blast_Score=158, Evalue=2e-39,
Organism=Escherichia coli, GI1787684, Length=460, Percent_Identity=28.4782608695652, Blast_Score=156, Evalue=8e-39,
Organism=Escherichia coli, GI1787558, Length=411, Percent_Identity=29.683698296837, Blast_Score=143, Evalue=6e-35,
Organism=Escherichia coli, GI87081896, Length=418, Percent_Identity=28.9473684210526, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI1786504, Length=467, Percent_Identity=28.051391862955, Blast_Score=136, Evalue=9e-33,
Organism=Escherichia coli, GI87082295, Length=471, Percent_Identity=28.0254777070064, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI87081926, Length=428, Percent_Identity=25.7009345794392, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI1787653, Length=261, Percent_Identity=24.1379310344828, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534447, Length=462, Percent_Identity=31.3852813852814, Blast_Score=183, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI25144435, Length=456, Percent_Identity=32.4561403508772, Blast_Score=173, Evalue=6e-43,
Organism=Caenorhabditis elegans, GI32564736, Length=412, Percent_Identity=33.0097087378641, Blast_Score=166, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17562198, Length=450, Percent_Identity=30.6666666666667, Blast_Score=165, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI115532534, Length=376, Percent_Identity=32.1808510638298, Blast_Score=158, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI115534176, Length=456, Percent_Identity=27.8508771929825, Blast_Score=149, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI25143874, Length=501, Percent_Identity=26.1477045908184, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI133930964, Length=441, Percent_Identity=27.437641723356, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=502, Percent_Identity=26.2948207171315, Blast_Score=143, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI32564151, Length=413, Percent_Identity=29.2978208232446, Blast_Score=142, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71986308, Length=427, Percent_Identity=28.8056206088993, Blast_Score=139, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17551164, Length=458, Percent_Identity=26.2008733624454, Blast_Score=130, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17534119, Length=459, Percent_Identity=25.7080610021786, Blast_Score=122, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71995606, Length=453, Percent_Identity=26.2693156732892, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71995613, Length=410, Percent_Identity=25.8536585365854, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=28.8079470198675, Blast_Score=110, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25146391, Length=412, Percent_Identity=23.5436893203883, Blast_Score=97, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=412, Percent_Identity=23.5436893203883, Blast_Score=97, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=412, Percent_Identity=23.5436893203883, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=330, Percent_Identity=25.7575757575758, Blast_Score=91, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320917, Length=457, Percent_Identity=31.9474835886214, Blast_Score=191, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6325196, Length=456, Percent_Identity=31.359649122807, Blast_Score=173, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6321826, Length=482, Percent_Identity=30.2904564315353, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6323821, Length=456, Percent_Identity=30.7017543859649, Blast_Score=164, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6324950, Length=451, Percent_Identity=27.9379157427938, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323822, Length=464, Percent_Identity=29.5258620689655, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6319478, Length=457, Percent_Identity=27.7899343544858, Blast_Score=133, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=587, Percent_Identity=21.8057921635434, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6323757, Length=326, Percent_Identity=26.0736196319018, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362580, Length=458, Percent_Identity=28.6026200873362, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI62472918, Length=458, Percent_Identity=28.6026200873362, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI62472926, Length=458, Percent_Identity=28.6026200873362, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI62472936, Length=458, Percent_Identity=28.6026200873362, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI21356737, Length=458, Percent_Identity=28.6026200873362, Blast_Score=167, Evalue=3e-41,
Organism=Drosophila melanogaster, GI20129399, Length=444, Percent_Identity=28.8288288288288, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24668425, Length=481, Percent_Identity=26.4033264033264, Blast_Score=157, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24668417, Length=481, Percent_Identity=26.4033264033264, Blast_Score=157, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24668413, Length=481, Percent_Identity=26.4033264033264, Blast_Score=157, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24650465, Length=448, Percent_Identity=28.3482142857143, Blast_Score=157, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28574525, Length=494, Percent_Identity=27.1255060728745, Blast_Score=150, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24666674, Length=454, Percent_Identity=27.5330396475771, Blast_Score=144, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24585660, Length=461, Percent_Identity=26.4642082429501, Blast_Score=144, Evalue=6e-34,
Organism=Drosophila melanogaster, GI28571806, Length=471, Percent_Identity=25.2653927813163, Blast_Score=140, Evalue=6e-33,
Organism=Drosophila melanogaster, GI28571802, Length=471, Percent_Identity=25.2653927813163, Blast_Score=140, Evalue=6e-33,
Organism=Drosophila melanogaster, GI28571800, Length=471, Percent_Identity=25.2653927813163, Blast_Score=140, Evalue=6e-33,
Organism=Drosophila melanogaster, GI28571798, Length=471, Percent_Identity=25.2653927813163, Blast_Score=140, Evalue=8e-33,
Organism=Drosophila melanogaster, GI28571796, Length=471, Percent_Identity=25.2653927813163, Blast_Score=140, Evalue=8e-33,
Organism=Drosophila melanogaster, GI28571794, Length=471, Percent_Identity=25.2653927813163, Blast_Score=140, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24638876, Length=428, Percent_Identity=26.6355140186916, Blast_Score=111, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24638878, Length=428, Percent_Identity=26.6355140186916, Blast_Score=111, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281360299, Length=335, Percent_Identity=28.6567164179104, Blast_Score=103, Evalue=8e-22,
Organism=Drosophila melanogaster, GI281360297, Length=335, Percent_Identity=28.6567164179104, Blast_Score=103, Evalue=8e-22,
Organism=Drosophila melanogaster, GI281360295, Length=335, Percent_Identity=28.6567164179104, Blast_Score=103, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24586250, Length=335, Percent_Identity=28.6567164179104, Blast_Score=103, Evalue=8e-22,
Organism=Drosophila melanogaster, GI281360301, Length=331, Percent_Identity=28.7009063444109, Blast_Score=103, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45552499, Length=335, Percent_Identity=26.865671641791, Blast_Score=97, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281360303, Length=331, Percent_Identity=26.8882175226586, Blast_Score=97, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 139936; Mature: 139805

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTTLGVKVDDLLRARLKDAASRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHTGVA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DLSDSHADGDDDGAPHPFLEFAQSVQPQSVLRAAITAAYRRPEPECVPFLIGEARLPASL
CCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHH
ASDVQAMAAGLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDAL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
IRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGKGGEPLI
HHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHHH
RKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDALRYYASY
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHHH
EQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQERTMNELLPRVRSLALLARRYD
HHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGLNIDAEEADRLELSLDLLEALCFDPELAGWNGIGFVVQAYQKRCPFVIDYLVDLARRS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
RHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQF
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
ATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHE
HCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCHH
TLLAYLVRRLLENGANTSFVNRIADKTVSVKELVADPVEDALKVVPLGAPHAKIALPREL
HHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCHHHHHHEECCCCCCCCEECCHHH
YGASRVNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLADDALAHAAPRDVRNPADLR
HCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHCCCHHHHH
DVVGTVSEATPDEVSAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLIVR
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGKSLPNAIAEIREAVDFLRYYSAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHH
AALAAGNTVLAKPAEQTPLIAAQAVRLLRDAGVPAGAVQLLPGNGETVGAALVADPRTRA
HHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEECCCCCE
VMFTGSTEVARLINKTLSSRLDPDGRPIPLIAETGGQNAMIVDSSALAEQVVADVLQSSF
EEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHH
DSAGQRCSALRVLCLQDDVADRTLTMLKGAMRELALGNPDRLSVDVGPVIDADAKRTIDT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
HIAAMKDKGHAVTQLEMPDACAQGTFVPPTIIEIGNVDELKREVFGPVLHVVRYRRSGLD
HHHHHHCCCCEEEEECCCCHHCCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KLLEQIRATGYGLTLGIHTRIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSG
HHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCCCCC
TGPKAGGALYLQRLLATRPAGLPRSLEAALVADAPQEGETRDNPSAALTALRDWLIEQRE
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
PALAARCDGYLSHVLAGATAVLSGPTGERNTYTLGARGTVLCIAATASGARAQFAAALAT
CHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHHHHHC
GNRALFAGAAGEALAAALPAQLKAHAGVRKQADAAFDAVLFEGDSDELLALVKEVAQRPG
CCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCC
PIVSVQGVAAGAFENGGDEDYALERLLTERSVSVNTAAAGGNANLMTIG
CEEEECCCEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC
>Mature Secondary Structure 
ASTTLGVKVDDLLRARLKDAASRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHTGVA
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DLSDSHADGDDDGAPHPFLEFAQSVQPQSVLRAAITAAYRRPEPECVPFLIGEARLPASL
CCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHH
ASDVQAMAAGLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDAL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
IRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGKGGEPLI
HHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHHH
RKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDALRYYASY
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHHH
EQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQERTMNELLPRVRSLALLARRYD
HHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGLNIDAEEADRLELSLDLLEALCFDPELAGWNGIGFVVQAYQKRCPFVIDYLVDLARRS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
RHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQF
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
ATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHE
HCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCHH
TLLAYLVRRLLENGANTSFVNRIADKTVSVKELVADPVEDALKVVPLGAPHAKIALPREL
HHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCCHHHHHHEECCCCCCCCEECCHHH
YGASRVNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLADDALAHAAPRDVRNPADLR
HCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHCCCHHHHH
DVVGTVSEATPDEVSAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLIVR
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGKSLPNAIAEIREAVDFLRYYSAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHH
AALAAGNTVLAKPAEQTPLIAAQAVRLLRDAGVPAGAVQLLPGNGETVGAALVADPRTRA
HHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEECCCCCE
VMFTGSTEVARLINKTLSSRLDPDGRPIPLIAETGGQNAMIVDSSALAEQVVADVLQSSF
EEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHH
DSAGQRCSALRVLCLQDDVADRTLTMLKGAMRELALGNPDRLSVDVGPVIDADAKRTIDT
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
HIAAMKDKGHAVTQLEMPDACAQGTFVPPTIIEIGNVDELKREVFGPVLHVVRYRRSGLD
HHHHHHCCCCEEEEECCCCHHCCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KLLEQIRATGYGLTLGIHTRIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSG
HHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCCCCC
TGPKAGGALYLQRLLATRPAGLPRSLEAALVADAPQEGETRDNPSAALTALRDWLIEQRE
CCCCCCHHHHHHHHHHHCCCCCCCHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
PALAARCDGYLSHVLAGATAVLSGPTGERNTYTLGARGTVLCIAATASGARAQFAAALAT
CHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHHHHHC
GNRALFAGAAGEALAAALPAQLKAHAGVRKQADAAFDAVLFEGDSDELLALVKEVAQRPG
CCCEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCC
PIVSVQGVAAGAFENGGDEDYALERLLTERSVSVNTAAAGGNANLMTIG
CEEEECCCEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]