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The map label for this gene is czcR [H]

Identifier: 237814192

GI number: 237814192

Start: 3826601

End: 3827539

Strand: Reverse

Name: czcR [H]

Synonym: GBP346_A3986

Alternate gene names: 237814192

Gene position: 3827539-3826601 (Counterclockwise)

Preceding gene: 237814194

Following gene: 237814185

Centisome position: 93.39

GC content: 71.99

Gene sequence:

>939_bases
TTGAATACGCGTGATCTTCAAGCTTTCGTGGCGGTCGTCGACAGCGGCTCGATGGTGGCCGCCGCGACCCGGCTCCATCT
GACGCAGCCCGGCCTGACGCGGCGCGTGCAGAACCTCGAGACGACGCTCGGCGTGCCGCTCCTCGATCGGCAGAGCAAGC
CGCTCAAGCCGACCGCGGCGGGCCGCGAGGTCTACGCGCTCGCGCGCAACGTGCTGCGCTCGGTCGACGAACTGCTGGCC
GTCGCGGCGCCCGGTAGCGAGCCGGCGGGCGAACTGCGGATCGGCGTGCCGCCGTTTTTGTCGGAGCTCGCGCTCGAAGA
GCCGATCGACCGGCTACGCGACGCGTTTCCGCGCCTCACGCTGCGGATCACGGCCGGCTGGTCGCCGGCGCTGCTGGAAA
ACGTCGAGCGCGCAGTGCTCGATGCCGCCGCGGTGATGATGCCGGCAAGCTTCCCGATGCCGGAGACGCTCGTGTCGACG
CTGCTCGGCGTGCAGCCGACGGTGCTCGTCGCCGCGCGCGATTTCGCGCTGCCGCCGGGGCCGCTGTCGCTCGACGCGCT
GGCGCGCTATCCGTGGGTGCTGAGCCAGGACGGCTGCGGGATGCGCTCCGCGCTGAGCCGCGCGTTCAGCGCGGCGGGGC
TGCCGTTCGACGTCGCGGTCGAAGCATTCGGCTCGGATCTGCAGCTCTCGCTCGTCGCGCGCGGCGCGGGGCTCGGCATC
GCATCGGCGTCCGCGCTCGCGCGCAGCCCGCACCGGAATGCGCTGCGGATCGTCGAAACGGTGGATGTCGAGCCGGGAAT
CAACGTGTGGCTCGTGCACGGCGTGCTGCCGGGCCGGCTGATGCGGCCCGTCGAGCTGCTGCGCGAGCGGCTCGCCGCGG
TGCTGGAGGAGGAAAGAAGCCGGCGGTTGGGCGGCGAAGCGGACATGCCGGCCAATTAG

Upstream 100 bases:

>100_bases
TTCATCGAAAGGATCTCGGGAAACGAACGAGCTCCTATCGTAGAGATGCGCTTGTTATGCGACAATTGAAATATGTCAAA
TATGATTATGCGAGTTTGTT

Downstream 100 bases:

>100_bases
AGCCGGCATTCAAGGGAAAATCCGTATTTTCTACAAGGAAATGTTGCATTGCGTCAAACAAACCGGTATAGTTTGAACCG
TCTCCTCCATGTCTCCTCTG

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MNTRDLQAFVAVVDSGSMVAAATRLHLTQPGLTRRVQNLETTLGVPLLDRQSKPLKPTAAGREVYALARNVLRSVDELLA
VAAPGSEPAGELRIGVPPFLSELALEEPIDRLRDAFPRLTLRITAGWSPALLENVERAVLDAAAVMMPASFPMPETLVST
LLGVQPTVLVAARDFALPPGPLSLDALARYPWVLSQDGCGMRSALSRAFSAAGLPFDVAVEAFGSDLQLSLVARGAGLGI
ASASALARSPHRNALRIVETVDVEPGINVWLVHGVLPGRLMRPVELLRERLAAVLEEERSRRLGGEADMPAN

Sequences:

>Translated_312_residues
MNTRDLQAFVAVVDSGSMVAAATRLHLTQPGLTRRVQNLETTLGVPLLDRQSKPLKPTAAGREVYALARNVLRSVDELLA
VAAPGSEPAGELRIGVPPFLSELALEEPIDRLRDAFPRLTLRITAGWSPALLENVERAVLDAAAVMMPASFPMPETLVST
LLGVQPTVLVAARDFALPPGPLSLDALARYPWVLSQDGCGMRSALSRAFSAAGLPFDVAVEAFGSDLQLSLVARGAGLGI
ASASALARSPHRNALRIVETVDVEPGINVWLVHGVLPGRLMRPVELLRERLAAVLEEERSRRLGGEADMPAN
>Mature_312_residues
MNTRDLQAFVAVVDSGSMVAAATRLHLTQPGLTRRVQNLETTLGVPLLDRQSKPLKPTAAGREVYALARNVLRSVDELLA
VAAPGSEPAGELRIGVPPFLSELALEEPIDRLRDAFPRLTLRITAGWSPALLENVERAVLDAAAVMMPASFPMPETLVST
LLGVQPTVLVAARDFALPPGPLSLDALARYPWVLSQDGCGMRSALSRAFSAAGLPFDVAVEAFGSDLQLSLVARGAGLGI
ASASALARSPHRNALRIVETVDVEPGINVWLVHGVLPGRLMRPVELLRERLAAVLEEERSRRLGGEADMPAN

Specific function: Transcriptional Activator For The Hut, Put And Ure Operons And Repressor For The Gdh And Gltb Operons In Response To Nitrogen Limitation. Negative Regulator Of Its Own Expression (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788297, Length=251, Percent_Identity=30.2788844621514, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=28.8, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790399, Length=315, Percent_Identity=27.3015873015873, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788481, Length=243, Percent_Identity=28.8065843621399, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789506, Length=221, Percent_Identity=24.4343891402715, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787879, Length=276, Percent_Identity=27.536231884058, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=264, Percent_Identity=26.8939393939394, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787806, Length=273, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788296, Length=272, Percent_Identity=25, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1789440, Length=196, Percent_Identity=27.5510204081633, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI157672245, Length=239, Percent_Identity=27.6150627615063, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1789639, Length=193, Percent_Identity=26.9430051813472, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33271; Mature: 33271

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTRDLQAFVAVVDSGSMVAAATRLHLTQPGLTRRVQNLETTLGVPLLDRQSKPLKPTAA
CCCHHHHHHHHHHCCCCEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GREVYALARNVLRSVDELLAVAAPGSEPAGELRIGVPPFLSELALEEPIDRLRDAFPRLT
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCEE
LRITAGWSPALLENVERAVLDAAAVMMPASFPMPETLVSTLLGVQPTVLVAARDFALPPG
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCC
PLSLDALARYPWVLSQDGCGMRSALSRAFSAAGLPFDVAVEAFGSDLQLSLVARGAGLGI
CCCHHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCH
ASASALARSPHRNALRIVETVDVEPGINVWLVHGVLPGRLMRPVELLRERLAAVLEEERS
HHHHHHHCCCCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
RRLGGEADMPAN
HHCCCCCCCCCC
>Mature Secondary Structure
MNTRDLQAFVAVVDSGSMVAAATRLHLTQPGLTRRVQNLETTLGVPLLDRQSKPLKPTAA
CCCHHHHHHHHHHCCCCEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GREVYALARNVLRSVDELLAVAAPGSEPAGELRIGVPPFLSELALEEPIDRLRDAFPRLT
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCEE
LRITAGWSPALLENVERAVLDAAAVMMPASFPMPETLVSTLLGVQPTVLVAARDFALPPG
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCC
PLSLDALARYPWVLSQDGCGMRSALSRAFSAAGLPFDVAVEAFGSDLQLSLVARGAGLGI
CCCHHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCH
ASASALARSPHRNALRIVETVDVEPGINVWLVHGVLPGRLMRPVELLRERLAAVLEEERS
HHHHHHHCCCCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
RRLGGEADMPAN
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA