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The map label for this gene is aroB [H]

Identifier: 237814098

GI number: 237814098

Start: 3735683

End: 3736762

Strand: Reverse

Name: aroB [H]

Synonym: GBP346_A3884

Alternate gene names: 237814098

Gene position: 3736762-3735683 (Counterclockwise)

Preceding gene: 237814099

Following gene: 237814097

Centisome position: 91.17

GC content: 68.15

Gene sequence:

>1080_bases
ATGATTACCGTCAACGTCGACCTGGGCGAGCGCGCCTATCCGATCCACATCGGCGCCGATCTGATCGGCCGCACCGAGCT
TTTCGCGCCGCACATCGCGGGCGCATCCGTCACGATCGTCACGAACACCACCGTCGAGCCGCTCTACGGCGACACGCTGC
GCGCCGCGCTCGCGCCGCTCGGCAAGCGCGTGTCGACCGTCGTCCTGCCCGACGGCGAAGCGTACAAGAACTGGGAAACG
CTCAATCTGATCTTCGATGGCCTGCTCGAGCAGCACGCCGATCGCAAGACGACGCTGATCGCGCTCGGCGGCGGCGTGAT
CGGCGACATGACGGGCTTCGCGGCCGCATGCTACATGCGCGGCGTGCCGTTCATCCAGGTGCCGACGACGCTCCTGTCGC
AGGTTGATTCGTCGGTCGGCGGCAAGACGGGCATCAACCATCCGCTCGGCAAGAACATGATCGGCGCGTTCTATCAGCCG
CAGGCGGTGATCGCCGATATCGGCGCGCTGTCGACGCTGCCCGATCGCGAGCTTGCCGCGGGCGTCGCCGAGATCGTCAA
GACGGGCGCGATCGCCGATGCCGCGTTCTTCGACTGGATCGAGGCGAACGTGGGCGCGCTCACTCGCCGCGATCCCGACG
CGCTCGCGCACGCGGTCAAGCGCTCGTGCGAGATCAAGGCGGGCGTCGTCGCGGCGGACGAGCGCGAGGGCGGTCTGCGC
GCGATCCTCAATTTTGGCCATACGTTCGGGCACGCGATCGAAGCGGGGCTCGGCTACGGCGAGTGGCTGCACGGCGAGGC
GGTGGGCTGCGGCATGGTGATGGCGGCCGACCTGTCGGTGCGAACCGGCCATCTCGACGAAGCGTCGCGCGCGCGGCTGT
GCCGCGTCGTCGAGGCCGCGCATCTGCCGACGCGCGCGCCGGATCTCGGCGACGCGCGTTATGTCGAGCTGATGCGCGTC
GACAAGAAGGCCGAGGCGGGCGCGATCAAGTTCATACTGCTCAAACGCTTCGGCGAAACGATCATCACTCCGGCGCCCGA
CGACGCCGTTCTCGCGACACTGGCGGCAACCACCCGGTAA

Upstream 100 bases:

>100_bases
ACTTCGTCATCGAAACCGGGCGGCCGTCCGTCAACGGGCTCGTCAACATGGTGCTGATGCAGCTCGAAATGGCGGGCATC
GTCGCCAAGCCACTCCAAGC

Downstream 100 bases:

>100_bases
ACGCGATACGGGCCGATCCGGCGCAATTGACGTGGAGGACACGACACGGTGAGCGAAATACCCGGCGGCGGCATCCCGCG
CGAAACCCGCGACGCGCGCG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MITVNVDLGERAYPIHIGADLIGRTELFAPHIAGASVTIVTNTTVEPLYGDTLRAALAPLGKRVSTVVLPDGEAYKNWET
LNLIFDGLLEQHADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALSTLPDRELAAGVAEIVKTGAIADAAFFDWIEANVGALTRRDPDALAHAVKRSCEIKAGVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRTGHLDEASRARLCRVVEAAHLPTRAPDLGDARYVELMRV
DKKAEAGAIKFILLKRFGETIITPAPDDAVLATLAATTR

Sequences:

>Translated_359_residues
MITVNVDLGERAYPIHIGADLIGRTELFAPHIAGASVTIVTNTTVEPLYGDTLRAALAPLGKRVSTVVLPDGEAYKNWET
LNLIFDGLLEQHADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALSTLPDRELAAGVAEIVKTGAIADAAFFDWIEANVGALTRRDPDALAHAVKRSCEIKAGVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRTGHLDEASRARLCRVVEAAHLPTRAPDLGDARYVELMRV
DKKAEAGAIKFILLKRFGETIITPAPDDAVLATLAATTR
>Mature_359_residues
MITVNVDLGERAYPIHIGADLIGRTELFAPHIAGASVTIVTNTTVEPLYGDTLRAALAPLGKRVSTVVLPDGEAYKNWET
LNLIFDGLLEQHADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQP
QAVIADIGALSTLPDRELAAGVAEIVKTGAIADAAFFDWIEANVGALTRRDPDALAHAVKRSCEIKAGVVAADEREGGLR
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRTGHLDEASRARLCRVVEAAHLPTRAPDLGDARYVELMRV
DKKAEAGAIKFILLKRFGETIITPAPDDAVLATLAATTR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=341, Percent_Identity=55.425219941349, Blast_Score=358, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320332, Length=372, Percent_Identity=38.7096774193548, Blast_Score=217, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 37896; Mature: 37896

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVNVDLGERAYPIHIGADLIGRTELFAPHIAGASVTIVTNTTVEPLYGDTLRAALAPL
CEEEEEECCCCEEEEEECCCHHCCHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
GKRVSTVVLPDGEAYKNWETLNLIFDGLLEQHADRKTTLIALGGGVIGDMTGFAAACYMR
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALSTLPDRELAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
GVAEIVKTGAIADAAFFDWIEANVGALTRRDPDALAHAVKRSCEIKAGVVAADEREGGLR
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEECEEEECCCCCCHH
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRTGHLDEASRARLCRVVEAA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEECCCCCHHHHHHHHHHHHHH
HLPTRAPDLGDARYVELMRVDKKAEAGAIKFILLKRFGETIITPAPDDAVLATLAATTR
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MITVNVDLGERAYPIHIGADLIGRTELFAPHIAGASVTIVTNTTVEPLYGDTLRAALAPL
CEEEEEECCCCEEEEEECCCHHCCHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHH
GKRVSTVVLPDGEAYKNWETLNLIFDGLLEQHADRKTTLIALGGGVIGDMTGFAAACYMR
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALSTLPDRELAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHH
GVAEIVKTGAIADAAFFDWIEANVGALTRRDPDALAHAVKRSCEIKAGVVAADEREGGLR
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCEECEEEECCCCCCHH
AILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRTGHLDEASRARLCRVVEAA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCEEECCCCCHHHHHHHHHHHHHH
HLPTRAPDLGDARYVELMRVDKKAEAGAIKFILLKRFGETIITPAPDDAVLATLAATTR
CCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA