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The map label for this gene is hitA [H]

Identifier: 237814056

GI number: 237814056

Start: 3696036

End: 3696401

Strand: Reverse

Name: hitA [H]

Synonym: GBP346_A3841

Alternate gene names: 237814056

Gene position: 3696401-3696036 (Counterclockwise)

Preceding gene: 237814057

Following gene: 237814055

Centisome position: 90.19

GC content: 66.94

Gene sequence:

>366_bases
ATGAATCACGACCCGAACTGCCTGTTCTGCAAGATCGCGGCAGGCGAGATTCCGAGCACGAAGGTGCACGAGGACGACGA
GTTCGTCGCCTTCCGGGATATCCGGCCCGCGGCCGACACGCACGTGCTCGTGATACCGCGCAAGCATTTGCCGACGCTGT
CCGCCGTCACCGCGGACGACGCGCCGCTGCTTGGTAGAATGATGGTTCTCGTCGCGCGGCTCGCCGAGCGGTTGGGCTGC
GCATATACGGGCGGCGAAACCGGGTTCCGGACGGTGATCAACACCGGCCCGGGCGGCGGGCAGGAGGTCTACCACCTGCA
CGCGCATATTCTGGCCGGGCCGCGTCCGTGGCGCCGGATGGGATGA

Upstream 100 bases:

>100_bases
CTGTACCGTATCATCAAAGGCTGGCTGTACTTGAACGACAACAAGACGCTCGATCCGCAGGCATGGTTCTGACGCCGCGG
CGAACGCGTCGGGGAACGCG

Downstream 100 bases:

>100_bases
GATGGCGGGCGGCCCGCCATCGGAACGATGCCGGCACGGGGCCGGCGATTTGCGCCGCGAGACCGGCGAGGTTTAGGAGA
GTTTCATCATGGGCGGATTG

Product: HIT family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MNHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRKHLPTLSAVTADDAPLLGRMMVLVARLAERLGC
AYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWRRMG

Sequences:

>Translated_121_residues
MNHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRKHLPTLSAVTADDAPLLGRMMVLVARLAERLGC
AYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWRRMG
>Mature_121_residues
MNHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRKHLPTLSAVTADDAPLLGRMMVLVARLAERLGC
AYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWRRMG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=108, Percent_Identity=44.4444444444444, Blast_Score=97, Evalue=3e-21,
Organism=Homo sapiens, GI14211923, Length=107, Percent_Identity=37.3831775700935, Blast_Score=82, Evalue=8e-17,
Organism=Homo sapiens, GI189217863, Length=114, Percent_Identity=31.5789473684211, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1787346, Length=112, Percent_Identity=47.3214285714286, Blast_Score=91, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17506713, Length=108, Percent_Identity=42.5925925925926, Blast_Score=97, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24581222, Length=108, Percent_Identity=48.1481481481481, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28574010, Length=108, Percent_Identity=48.1481481481481, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 13192; Mature: 13192

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRKHLPTLSAVTADD
CCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEECCCC
APLLGRMMVLVARLAERLGCAYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWRRM
CCHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCC
G
C
>Mature Secondary Structure
MNHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRKHLPTLSAVTADD
CCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEECCCC
APLLGRMMVLVARLAERLGCAYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWRRM
CCHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEECCCCCCCEEEEEEEEEECCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA