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The map label for this gene is mraY [H]

Identifier: 237813922

GI number: 237813922

Start: 3570867

End: 3572036

Strand: Reverse

Name: mraY [H]

Synonym: GBP346_A3701

Alternate gene names: 237813922

Gene position: 3572036-3570867 (Counterclockwise)

Preceding gene: 237813923

Following gene: 237813921

Centisome position: 87.15

GC content: 63.42

Gene sequence:

>1170_bases
ATGCTGCTGGCGTTGGCGCAATGGCTGCAAGGTGACGCAAGCTTTTTGCGCTTGTTCACGTACCTGACGTTCCGGGCGGT
GATGGCCACCATCACGGCGCTCGTGATCGGTCTCGTCTGCGGCCCGTGGGTGATCCGCAAGCTCACGCAGATGAAGGTCG
GCCAGGCGGTGCGCAAGGACGGCCCGCAGACGCACCTCGTGAAATCGGGCACGCCGACGATGGGCGGCGTGCTGATCCTG
ATCGGCATCGCGGTCGCGACGCTGCTCTGGGGCGATCTGACGAACCGCTTCATCTGGATCGTGATGCTCGTCACGTTCGG
CTTCGGCGTGATCGGCTGGGTCGACGACTATCGCAAGGTCGTCTACAAGGACCCGCGCGGCATGTCGTCGCGCGAAAAGT
ATTTCTGGCAATCGGTGATCGGCCTGTTCGCGGCCGTCTATCTCGCGTTCAGCGTGTCCGAGGCGAACAACGTCCGCGTG
TTCGACCTGTTCATGGCCTGGGTGCGAAGCGGGCTGTCGATGGGGCTGCCGGCGCGCGCGGACCTGATGCTGCCGTTCCT
GAAGTCGATCAGCTATCCGCTCGGCGTCTGGGGCTTCATCGCGCTCACGTATTTCGTGATCGTCGGCGCGAGCAACGCGG
TGAACCTCACCGACGGGCTCGACGGCCTCGTGATCATGCCGGTCGTGCTCGTGGGCGCGTCGCTCGGCGTGTTCGCGTAC
GTGATGGGCAGCGCCGTCTATTCGAAATATCTGCTGTTCCCGCACATTCCGGGCGCGGGCGAGCTGCTGATCTTCTGCTC
GGCGATGGGCGGCGCGGGGCTCGCGTTCCTCTGGTACAACACGCACCCCGCGCAGGTATTCATGGGCGACGTCGGCGCGC
TCGCGCTGGGCGGCGCGCTCGGCACGGTCGCCGTGATCGTGCGTCAGGAAATCGTGCTGTTCATCATGGGCGGCATCTTC
GTCGCGGAGACGCTGTCGGTGATGTTGCAGGTCACGTGGTTCAAGTACACGAAAAAGCGTTACGGCGAAGGGCGGCGCAT
CTTCAAGATGGCGCCGCTGCATCACCATTTCGAATTGTCGGGCTGGAAGGAAACGCAGGTGGTGGTGCGTTTCTGGATCA
TCACGTTGATGCTGTGCCTGTTCGGTTTGTCCACCCTCAAGCTGCGGTAA

Upstream 100 bases:

>100_bases
AGGGCTCGCGGTTCATGAAGATGGAGCGCGTGGTCGACGCGCTCGCGAACGAAACCGCGTCGGGCGCAGCGCCCGGCGCA
CACTGAGGAAGGAAGTAAGC

Downstream 100 bases:

>100_bases
AGGGAAGGTAAGGATGTTTGGCGAGATGTTCGGAGATCGGCAGCGGCCGATGGTGCTCGTGCTGGGGCTCGGCGAATCGG
GCCTCGCGATCGCGCGGTGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MLLALAQWLQGDASFLRLFTYLTFRAVMATITALVIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLIL
IGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRV
FDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIALTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIF
VAETLSVMLQVTWFKYTKKRYGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR

Sequences:

>Translated_389_residues
MLLALAQWLQGDASFLRLFTYLTFRAVMATITALVIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLIL
IGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRV
FDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIALTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIF
VAETLSVMLQVTWFKYTKKRYGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR
>Mature_389_residues
MLLALAQWLQGDASFLRLFTYLTFRAVMATITALVIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLIL
IGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRV
FDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIALTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAY
VMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIF
VAETLSVMLQVTWFKYTKKRYGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=389, Percent_Identity=52.1850899742931, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 42883; Mature: 42883

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure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CCCHHHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA