| Definition | Burkholderia pseudomallei MSHR346 chromosome I, complete genome. |
|---|---|
| Accession | NC_012695 |
| Length | 4,098,576 |
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The map label for this gene is secA [H]
Identifier: 237813909
GI number: 237813909
Start: 3554926
End: 3557721
Strand: Reverse
Name: secA [H]
Synonym: GBP346_A3688
Alternate gene names: 237813909
Gene position: 3557721-3554926 (Counterclockwise)
Preceding gene: 237813912
Following gene: 237813908
Centisome position: 86.8
GC content: 65.52
Gene sequence:
>2796_bases ATGACAACCGGTTTTCTTCAGAAAATTTTTGGCAGCCGCAATCAGCGGCTCGTCAAGCAATACCAAAAGACCGTCGCGGC GATCAATGCGCTTGAAACGCAGATCGAGACGCTGACGGACGACCAGTTGCGCGGCAAGACAGGGGAGTTCCGTCAGCGCA TCGCGGCCGGCGAGTCGCTCGACAAGCTCCTGCCCGAGGCGTTCGCCGTGTGCCGCGAGGCGAGCCGCCGCGTGCTGAAG ATGCGCCACTTCGACGTGCAGATGATCGGCGGGATGGTGCTGCATTACGGCAAGATCGCCGAAATGCGCACGGGCGAGGG CAAGACGCTCGTCGCGACGCTCGCCGCGTACCTGAACGCGCTCGCCGGCCGCGGCGTGCACGTCGTGACGGTCAACGATT ACCTCGCGCAGCGCGACGCCGAGTGGATGGGCCGGCTCTACAACTTCCTCGGGCTTTCGGTCGGCATCAACCTCTCGGGG ATGGAGCACGACCAGAAGCAGGCGGCGTACGCAGCCGACATCACGTACGGCACGAACAACGAATTCGGTTTCGACTACCT GCGCGACAACATGGTCTACGAGACCGATTCGCGCGTGCAGCGGCCGCTGAATTTCGCGGTGGTCGACGAAGTCGACTCGA TCCTGATCGACGAAGCGCGCACGCCGCTCATCATCTCGGGCCAGGCTGAGGATCACACCGAGCTGTACGTGCGGATGAAC GCGCTGCCGCCGCTGCTCGAGCGCCAGATCGGCGAGGAGAAGGCGGACGGCACGGGCGTCGAGAAGCCGGGCGACTACAC GCTCGACGAGAAGGGCCGCCAGGTGTTCCTGACCGAGTCGGGCCATGAGAAGGCCGAGCGGATGCTCGCCGAATGGGGCT TGATCGGCGACGGCGAGAGCCTCTACGCGCCGCAGAACATCACGCTGATGCACCATGTGTACGCGGCGCTGCGCGCGCAC ACGCTGTTCCATCGCGATCAGCACTACGTCGTGCAGAACGACGAGGTGATCATCGTCGACGAATTCACGGGCCGCCTGAT GCCGGGCCGCCGCTGGTCCGACGGCCTGCACCAGGCGGTCGAGGCGAAGGAGCACGTGAAGATCCAGAGCGAGAACCAGA CGCTCGCGTCGATCACGTTCCAGAACTACTTCCGGATGTACGCGAAGCTCTCGGGCATGACGGGCACGGCGGACACCGAG GCGTACGAATTCAACGAGATCTACGGCCTCGAGACGGTCGTGATCCCGACCAACCGGCCGCCGAAGCGGATCGACAAGCA GGATCAGATCTACAAGACCGCGAAGGAGCGCTACGACGCGGTGATCCGCGACATCCGCGAGTGCCACGAGCGCGGCCAGC CCGTGCTCGTCGGCACGACGTCGATCGAGAACTCGGAGCTGCTGTCGCACCTGCTCAAGCAGGCGGGCCTGCCTCACGAG GTGCTGAACGCGAAGCAGCACGCGCGCGAAGCGGCGATCGTCGCCGAGGCGGGCCGGCCGAAGCGCATCACGATCGCGAC GAACATGGCGGGCCGCGGCACCGATATCGTGCTCGGCGGCAACGTCGAGAAGCAGGCGGCGTTCATCGAGGCCGACGAAT CGATTCCGGCCGACGAGAAGGCGCGCCGCATCCAGCAACTGCACGACGAGTGGGAAACGCTGCACGAGCAGGTGAAGACC GCGGGCGGCCTGCACATCATCGGCACCGAGCGCCACGAGTCGCGCCGGATCGACAATCAGTTGCGCGGCCGCGCGGGCCG TCAGGGCGATCCGGGCTCGTCGCGCTTCTACCTGTCGCTCGAGGATCCGCTGTTGCGCATCTTCGCGGGCGACCGCGTGC GCGCGATCATGGACCGCCTGAAGATGCCGGAGGGCGAGGCGATCGAAGCGGGCATCGTCACGCGTTCGATCGAGTCCGCG CAACGCAAGGTCGAAGCGCGCAACTTCGATATCCGCAAGCAGCTGCTCGAATACGACGACGTGTCGAACGATCAGCGCAA GGTGATCTACCAGCAGCGCAACGAGCTGCTCGAAGCGCACGACATCGCCGAAACGATCGGCGCGATGCGTCACGGCGTGA TCTCGGAAGTGGTTCGCCAGTTCGTGCCGGCGGGCAGCATCGAGGAGCAGTGGGATCTGCCCGAGCTCGAAGAGACGCTG CGCAACGATTGGCAACTGGACCTCGCGATCCAGGAAATGGTGAACGAGTCGTCGTCGATCAACGCGGACGAGATCCTCGA CGCCGTCACGACGGCCGCCGACGAACACTACGAAGCGAAGGTCGCGCTGGTCGGCCGCGAATCGTTCAGCGCGTTCGAGC GCTCGATCATGCTGCAGACGCTCGACCGGCTGTGGCGCGAGCACCTCGCGGCGCTCGATCATCTGCGTCAGGGCATTCAC CTGCGCGGCTATGCGCAGAAGAACCCGAAGCAGGAATACAAGCGCGAGGCGTTCGAACTGTTCGCGGCGATGCTCGATGC GGTGAAGCAGGAAGTCACGCGGATCGTGATGAACGTGCAGATCCAGTCGCCCGAGCAGCTCGAGGAGGCAGCCGAGCAGA TCGAGGAGCAGGGCGGCCAGCTCGGCAACGTCGAGTTCCAGCACGCCGATTTCGCGGCGGCGGCGGCCGCGGCGACGGCG GGCGGCGCGGTGGTCGCGGATGCGACGGCCGAGATGGTTAGCCACGCGATGAGCCACAGCGGCCCGGCGGGCGAAGTGCC GCGAGTCGGCCGCAACGATCCGTGCCCGTGCGGCAGCGGCAAGAAGTACAAGCACTGTCACGGCAAGCTGAACTGA
Upstream 100 bases:
>100_bases CGACGTTTGAATTCACTTCTACGCTAAGCCGCCGAGGCTCGGCGCGCCGGGGAGGGCGTTCACCGCTCCGGGGCCGTTGC ACCGACGCACACCCGATCCG
Downstream 100 bases:
>100_bases CGTGATCGAAAGCGGCGCGCGAGCGCGCCGCGTCGTCTGTGCGCAAGACTCTCCAGGTGTCACGCGCGGCGGCGCGCGAG CGGCCGCCGGTTCTTCAATC
Product: preprotein translocase subunit SecA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 931; Mature: 930
Protein sequence:
>931_residues MTTGFLQKIFGSRNQRLVKQYQKTVAAINALETQIETLTDDQLRGKTGEFRQRIAAGESLDKLLPEAFAVCREASRRVLK MRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLAAYLNALAGRGVHVVTVNDYLAQRDAEWMGRLYNFLGLSVGINLSG MEHDQKQAAYAADITYGTNNEFGFDYLRDNMVYETDSRVQRPLNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN ALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERMLAEWGLIGDGESLYAPQNITLMHHVYAALRAH TLFHRDQHYVVQNDEVIIVDEFTGRLMPGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTE AYEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRECHERGQPVLVGTTSIENSELLSHLLKQAGLPHE VLNAKQHAREAAIVAEAGRPKRITIATNMAGRGTDIVLGGNVEKQAAFIEADESIPADEKARRIQQLHDEWETLHEQVKT AGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDPLLRIFAGDRVRAIMDRLKMPEGEAIEAGIVTRSIESA QRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEAHDIAETIGAMRHGVISEVVRQFVPAGSIEEQWDLPELEETL RNDWQLDLAIQEMVNESSSINADEILDAVTTAADEHYEAKVALVGRESFSAFERSIMLQTLDRLWREHLAALDHLRQGIH LRGYAQKNPKQEYKREAFELFAAMLDAVKQEVTRIVMNVQIQSPEQLEEAAEQIEEQGGQLGNVEFQHADFAAAAAAATA GGAVVADATAEMVSHAMSHSGPAGEVPRVGRNDPCPCGSGKKYKHCHGKLN
Sequences:
>Translated_931_residues MTTGFLQKIFGSRNQRLVKQYQKTVAAINALETQIETLTDDQLRGKTGEFRQRIAAGESLDKLLPEAFAVCREASRRVLK MRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLAAYLNALAGRGVHVVTVNDYLAQRDAEWMGRLYNFLGLSVGINLSG MEHDQKQAAYAADITYGTNNEFGFDYLRDNMVYETDSRVQRPLNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN ALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERMLAEWGLIGDGESLYAPQNITLMHHVYAALRAH TLFHRDQHYVVQNDEVIIVDEFTGRLMPGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTE AYEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRECHERGQPVLVGTTSIENSELLSHLLKQAGLPHE VLNAKQHAREAAIVAEAGRPKRITIATNMAGRGTDIVLGGNVEKQAAFIEADESIPADEKARRIQQLHDEWETLHEQVKT AGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDPLLRIFAGDRVRAIMDRLKMPEGEAIEAGIVTRSIESA QRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEAHDIAETIGAMRHGVISEVVRQFVPAGSIEEQWDLPELEETL RNDWQLDLAIQEMVNESSSINADEILDAVTTAADEHYEAKVALVGRESFSAFERSIMLQTLDRLWREHLAALDHLRQGIH LRGYAQKNPKQEYKREAFELFAAMLDAVKQEVTRIVMNVQIQSPEQLEEAAEQIEEQGGQLGNVEFQHADFAAAAAAATA GGAVVADATAEMVSHAMSHSGPAGEVPRVGRNDPCPCGSGKKYKHCHGKLN >Mature_930_residues TTGFLQKIFGSRNQRLVKQYQKTVAAINALETQIETLTDDQLRGKTGEFRQRIAAGESLDKLLPEAFAVCREASRRVLKM RHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLAAYLNALAGRGVHVVTVNDYLAQRDAEWMGRLYNFLGLSVGINLSGM EHDQKQAAYAADITYGTNNEFGFDYLRDNMVYETDSRVQRPLNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMNA LPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERMLAEWGLIGDGESLYAPQNITLMHHVYAALRAHT LFHRDQHYVVQNDEVIIVDEFTGRLMPGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTEA YEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRECHERGQPVLVGTTSIENSELLSHLLKQAGLPHEV LNAKQHAREAAIVAEAGRPKRITIATNMAGRGTDIVLGGNVEKQAAFIEADESIPADEKARRIQQLHDEWETLHEQVKTA GGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDPLLRIFAGDRVRAIMDRLKMPEGEAIEAGIVTRSIESAQ RKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEAHDIAETIGAMRHGVISEVVRQFVPAGSIEEQWDLPELEETLR NDWQLDLAIQEMVNESSSINADEILDAVTTAADEHYEAKVALVGRESFSAFERSIMLQTLDRLWREHLAALDHLRQGIHL RGYAQKNPKQEYKREAFELFAAMLDAVKQEVTRIVMNVQIQSPEQLEEAAEQIEEQGGQLGNVEFQHADFAAAAAAATAG GAVVADATAEMVSHAMSHSGPAGEVPRVGRNDPCPCGSGKKYKHCHGKLN
Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the pr
COG id: COG0653
COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the secA family [H]
Homologues:
Organism=Escherichia coli, GI1786287, Length=933, Percent_Identity=59.1639871382637, Blast_Score=1087, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004027 - InterPro: IPR000185 - InterPro: IPR020937 - InterPro: IPR011115 - InterPro: IPR014018 - InterPro: IPR011130 - InterPro: IPR011116 [H]
Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]
EC number: NA
Molecular weight: Translated: 104416; Mature: 104285
Theoretical pI: Translated: 5.43; Mature: 5.43
Prosite motif: PS01312 SECA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTTGFLQKIFGSRNQRLVKQYQKTVAAINALETQIETLTDDQLRGKTGEFRQRIAAGESL CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHCCCHH DKLLPEAFAVCREASRRVLKMRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLAAYLNA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH LAGRGVHVVTVNDYLAQRDAEWMGRLYNFLGLSVGINLSGMEHDQKQAAYAADITYGTNN HHCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEEEEECCCC EFGFDYLRDNMVYETDSRVQRPLNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN CCCHHHHHCCCEEECCHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEC ALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERMLAEWGLIGDGES CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCC LYAPQNITLMHHVYAALRAHTLFHRDQHYVVQNDEVIIVDEFTGRLMPGRRWSDGLHQAV CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCCCHHHHHHHH EAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTEAYEFNEIYGLETVVIPTNRP HHHHHCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCEEEEECCCCC PKRIDKQDQIYKTAKERYDAVIRDIRECHERGQPVLVGTTSIENSELLSHLLKQAGLPHE HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHH VLNAKQHAREAAIVAEAGRPKRITIATNMAGRGTDIVLGGNVEKQAAFIEADESIPADEK HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCCHHHHEEECCCCCCCHHH ARRIQQLHDEWETLHEQVKTAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSL HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE EDPLLRIFAGDRVRAIMDRLKMPEGEAIEAGIVTRSIESAQRKVEARNFDIRKQLLEYDD CCCHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC VSNDQRKVIYQQRNELLEAHDIAETIGAMRHGVISEVVRQFVPAGSIEEQWDLPELEETL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH RNDWQLDLAIQEMVNESSSINADEILDAVTTAADEHYEAKVALVGRESFSAFERSIMLQT HCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHH LDRLWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLDAVKQEVTRIVMNVQ HHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE IQSPEQLEEAAEQIEEQGGQLGNVEFQHADFAAAAAAATAGGAVVADATAEMVSHAMSHS CCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCC GPAGEVPRVGRNDPCPCGSGKKYKHCHGKLN CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure TTGFLQKIFGSRNQRLVKQYQKTVAAINALETQIETLTDDQLRGKTGEFRQRIAAGESL CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHCCCHH DKLLPEAFAVCREASRRVLKMRHFDVQMIGGMVLHYGKIAEMRTGEGKTLVATLAAYLNA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH LAGRGVHVVTVNDYLAQRDAEWMGRLYNFLGLSVGINLSGMEHDQKQAAYAADITYGTNN HHCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEEEEECCCC EFGFDYLRDNMVYETDSRVQRPLNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMN CCCHHHHHCCCEEECCHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEC ALPPLLERQIGEEKADGTGVEKPGDYTLDEKGRQVFLTESGHEKAERMLAEWGLIGDGES CCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCC LYAPQNITLMHHVYAALRAHTLFHRDQHYVVQNDEVIIVDEFTGRLMPGRRWSDGLHQAV CCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCCCHHHHHHHH EAKEHVKIQSENQTLASITFQNYFRMYAKLSGMTGTADTEAYEFNEIYGLETVVIPTNRP HHHHHCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCEEEEECCCCC PKRIDKQDQIYKTAKERYDAVIRDIRECHERGQPVLVGTTSIENSELLSHLLKQAGLPHE HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCHH VLNAKQHAREAAIVAEAGRPKRITIATNMAGRGTDIVLGGNVEKQAAFIEADESIPADEK HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEECCCCCHHHHEEECCCCCCCHHH ARRIQQLHDEWETLHEQVKTAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSL HHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE EDPLLRIFAGDRVRAIMDRLKMPEGEAIEAGIVTRSIESAQRKVEARNFDIRKQLLEYDD CCCHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC VSNDQRKVIYQQRNELLEAHDIAETIGAMRHGVISEVVRQFVPAGSIEEQWDLPELEETL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH RNDWQLDLAIQEMVNESSSINADEILDAVTTAADEHYEAKVALVGRESFSAFERSIMLQT HCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHH LDRLWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLDAVKQEVTRIVMNVQ HHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE IQSPEQLEEAAEQIEEQGGQLGNVEFQHADFAAAAAAATAGGAVVADATAEMVSHAMSHS CCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCC GPAGEVPRVGRNDPCPCGSGKKYKHCHGKLN CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA