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The map label for this gene is qseD [H]

Identifier: 237813801

GI number: 237813801

Start: 3457284

End: 3458234

Strand: Reverse

Name: qseD [H]

Synonym: GBP346_A3579

Alternate gene names: 237813801

Gene position: 3458234-3457284 (Counterclockwise)

Preceding gene: 237813802

Following gene: 237813799

Centisome position: 84.38

GC content: 70.03

Gene sequence:

>951_bases
ATGGAACTCAAATGGCTCGAAGATTTCGTGTCGCTCGCGGAAACGCGCAGTTTCAGCCGCTCGGCCGAGCTGCGGCACGT
GTCGCAACCCGCGTTCTCGCGCCGGATCCAGGCGCTCGAGGCGTGGCTCGCGACCGAGCTGATCGATCGTTCGGTCTATC
CGACCCGCCTCACGCAGGCAGGCCAGGTGTTCTACGAGCAGGCGCTCGCGATACTGTCGCAGGCGCACGAGGCGCGCACG
CTGCTGCGCGGCCACGTCGGCGCGCCCGTGCCGACGATCGAGTTCGCGGTGCCGCACACGCTGTCGCTCACGTATTTTCC
GCGCTGGCTGCAGCGGATCGAGGCAAAAATGGGGCCGGTCCATACGCGGCTGCGCGCGCTGAACGTGCACGATGCGGTGC
TCTCGCTTGTCGAGGGCGGCTGCGATCTCGTGATGGGCTACCACCATCCGAGCCATCCCGTCGCGCTCGATCCGGCCCGC
TACGACATGCTGACGCTCGGCACGGAGCCGATCAGCCCGTTCTCGGCGCCCGGCCGCGGCGGCCGCGCGCGCTACGCGCT
GCCCGGCACGGCCGACGCGCCCGTGCCGTATCTGTCGTACACGCCCAATGCGTACCTCGGCCGGATGACGGAGGTGATCA
TCGCGAACGCGCGCGCGCCGCTCTTTCTCGACAAGGTCTACGAGACCGACATGGCCGAGGCGCTGAAGGCGATGGCGCTC
GCCGGGCACGGCGTCGCGTTCTTGCCGCACAGCGCGGTCGAGGACGCGCTCGCGAGCGGCCGCCTCGTGAGGCTCGGCCG
CGCGGCGAAGGGCGCCGCGGAGCCGTTCATGCTGACGATGGAGATCCGCCTGTACCGCGACAAGCTCGCGGCGCAGGGCG
ACGAGCCGCGGCAAAAGCTCGTGCGCACGCTGTGGGACGTCGTGCGCGAGGAACTCGGCGCGACCGCCTGA

Upstream 100 bases:

>100_bases
TTCGTGCGCGCCGCACGTCGATGCCCGGGGCAAGCGGCGCCCCGACCGTTAAAATGCGTGCTTTCCTCCCTCGCATCCGT
TTTGCGCAGCAAAGGCACGC

Downstream 100 bases:

>100_bases
GCGTCGCGCGGCGACGGCCGCGACCATGGCGACGGCGGCCCATGGCCCACCCGCCCACGGGCGGCCCGCGGCCGGACCCA
TGCCCGGCCCGCCGACGGGG

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQAGQVFYEQALAILSQAHEART
LLRGHVGAPVPTIEFAVPHTLSLTYFPRWLQRIEAKMGPVHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLTLGTEPISPFSAPGRGGRARYALPGTADAPVPYLSYTPNAYLGRMTEVIIANARAPLFLDKVYETDMAEALKAMAL
AGHGVAFLPHSAVEDALASGRLVRLGRAAKGAAEPFMLTMEIRLYRDKLAAQGDEPRQKLVRTLWDVVREELGATA

Sequences:

>Translated_316_residues
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQAGQVFYEQALAILSQAHEART
LLRGHVGAPVPTIEFAVPHTLSLTYFPRWLQRIEAKMGPVHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLTLGTEPISPFSAPGRGGRARYALPGTADAPVPYLSYTPNAYLGRMTEVIIANARAPLFLDKVYETDMAEALKAMAL
AGHGVAFLPHSAVEDALASGRLVRLGRAAKGAAEPFMLTMEIRLYRDKLAAQGDEPRQKLVRTLWDVVREELGATA
>Mature_316_residues
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQAGQVFYEQALAILSQAHEART
LLRGHVGAPVPTIEFAVPHTLSLTYFPRWLQRIEAKMGPVHTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPAR
YDMLTLGTEPISPFSAPGRGGRARYALPGTADAPVPYLSYTPNAYLGRMTEVIIANARAPLFLDKVYETDMAEALKAMAL
AGHGVAFLPHSAVEDALASGRLVRLGRAAKGAAEPFMLTMEIRLYRDKLAAQGDEPRQKLVRTLWDVVREELGATA

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=268, Percent_Identity=35.4477611940299, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1788887, Length=79, Percent_Identity=43.0379746835443, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34887; Mature: 34887

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GQVFYEQALAILSQAHEARTLLRGHVGAPVPTIEFAVPHTLSLTYFPRWLQRIEAKMGPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHCHH
HTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPARYDMLTLGTEPISPFSAPGRG
HHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCC
GRARYALPGTADAPVPYLSYTPNAYLGRMTEVIIANARAPLFLDKVYETDMAEALKAMAL
CCEEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AGHGVAFLPHSAVEDALASGRLVRLGRAAKGAAEPFMLTMEIRLYRDKLAAQGDEPRQKL
HCCCEEECCHHHHHHHHHCCCEEECCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHH
VRTLWDVVREELGATA
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MELKWLEDFVSLAETRSFSRSAELRHVSQPAFSRRIQALEAWLATELIDRSVYPTRLTQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GQVFYEQALAILSQAHEARTLLRGHVGAPVPTIEFAVPHTLSLTYFPRWLQRIEAKMGPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHCHH
HTRLRALNVHDAVLSLVEGGCDLVMGYHHPSHPVALDPARYDMLTLGTEPISPFSAPGRG
HHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEECCCCCCEEEECCCCCCCCCCCCCC
GRARYALPGTADAPVPYLSYTPNAYLGRMTEVIIANARAPLFLDKVYETDMAEALKAMAL
CCEEEECCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AGHGVAFLPHSAVEDALASGRLVRLGRAAKGAAEPFMLTMEIRLYRDKLAAQGDEPRQKL
HCCCEEECCHHHHHHHHHCCCEEECCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHH
VRTLWDVVREELGATA
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]