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The map label for this gene is apaH [H]

Identifier: 237813510

GI number: 237813510

Start: 3174023

End: 3174871

Strand: Direct

Name: apaH [H]

Synonym: GBP346_A3286

Alternate gene names: 237813510

Gene position: 3174023-3174871 (Clockwise)

Preceding gene: 237813492

Following gene: 237813519

Centisome position: 77.44

GC content: 70.44

Gene sequence:

>849_bases
ATGACAAATTTCTCCAGCAGCCCGCCGATCGCTTTCGGCGACCTCCAGGGCTGCCACGCCGCCTATCGGCAGCTCTTCGA
CACGCTCGCGCCGGCGGCCGACACCCCGCTCTGGTTCGCGGGCGACCTCGTCAACCGCGGCCCTGCCTCGCTCGCGACGC
TGCGCGAGATCGTCGCGCTCGGCGAGCGCGCGATCGCGGTGCTCGGCAATCATGATCTGCACCTGCTCGCGGTCGCGGCC
GGGATCCGCACGCTGAAGCCGGGCGACACGATCGGCGAGATTCTCGACGCGCCCGACGCCGACGATCTGATCGAATGGGT
GCGCCACCGGCCGTTCGCGCACTTCGAGCGCGGCATGCTGATGGTGCACGCGGGCCTGCTGCCGCAATGGGACGCGGCGC
TCGCGCTCGAACTCGCCGACGAACTTCAGCGCGCGTTGCGCGCGCCGAACTGGCGCGACACGCTGCGCAGCCTGTACGGC
AACGACCCCAATTGTTGGAGCCCGGATCTGAAGCACGCGGACCGGCTGCGAGTCGCATTCAACGCGTTCACGCGCATTCG
CTTCTGCACGCCGGAAGGCGCGATGGAGTTTCGGGCGAACGGCGGCCCGGCGGCCGCGCCCGCCGGCTACCTGCCCTGGT
TCGACGCGCCCGGACGGAAAACCTCCGACGTGACGGTCGTGTTCGGCCACTGGGCCGCGTTGGGGCTGATGCTGCGCGAG
AATCTGGTCGCGCTGGATTCGGGATGCGTGTGGGGCAACCGCCTGTCCGCCGTGCGGCTCGCCGACGATCCGGCCGCGCG
CGTGGTCACGCAGGTCGCATGCGAGCGCTGCGGCGCAGCGGACGAATAG

Upstream 100 bases:

>100_bases
GAGACCGATGCCAGGCCGGATTTTCTCCGTCGCCGTTCCACTCGGACCGAAGTGCCTTCTTGTGATACCGTGAACTCGGT
TTCGTCACGATTGCAAAGGA

Downstream 100 bases:

>100_bases
CCGCGCGGATGCCGATACGGGTGCCGATACGGGCGGCAGGCTTGCCGCCGCCCGTCCCCGCGCACGATTGAACGCCCCGC
ATTCGACCTGCACATCGCGC

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTNFSSSPPIAFGDLQGCHAAYRQLFDTLAPAADTPLWFAGDLVNRGPASLATLREIVALGERAIAVLGNHDLHLLAVAA
GIRTLKPGDTIGEILDAPDADDLIEWVRHRPFAHFERGMLMVHAGLLPQWDAALALELADELQRALRAPNWRDTLRSLYG
NDPNCWSPDLKHADRLRVAFNAFTRIRFCTPEGAMEFRANGGPAAAPAGYLPWFDAPGRKTSDVTVVFGHWAALGLMLRE
NLVALDSGCVWGNRLSAVRLADDPAARVVTQVACERCGAADE

Sequences:

>Translated_282_residues
MTNFSSSPPIAFGDLQGCHAAYRQLFDTLAPAADTPLWFAGDLVNRGPASLATLREIVALGERAIAVLGNHDLHLLAVAA
GIRTLKPGDTIGEILDAPDADDLIEWVRHRPFAHFERGMLMVHAGLLPQWDAALALELADELQRALRAPNWRDTLRSLYG
NDPNCWSPDLKHADRLRVAFNAFTRIRFCTPEGAMEFRANGGPAAAPAGYLPWFDAPGRKTSDVTVVFGHWAALGLMLRE
NLVALDSGCVWGNRLSAVRLADDPAARVVTQVACERCGAADE
>Mature_281_residues
TNFSSSPPIAFGDLQGCHAAYRQLFDTLAPAADTPLWFAGDLVNRGPASLATLREIVALGERAIAVLGNHDLHLLAVAAG
IRTLKPGDTIGEILDAPDADDLIEWVRHRPFAHFERGMLMVHAGLLPQWDAALALELADELQRALRAPNWRDTLRSLYGN
DPNCWSPDLKHADRLRVAFNAFTRIRFCTPEGAMEFRANGGPAAAPAGYLPWFDAPGRKTSDVTVVFGHWAALGLMLREN
LVALDSGCVWGNRLSAVRLADDPAARVVTQVACERCGAADE

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=256, Percent_Identity=44.140625, Blast_Score=216, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 30626; Mature: 30495

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNFSSSPPIAFGDLQGCHAAYRQLFDTLAPAADTPLWFAGDLVNRGPASLATLREIVAL
CCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCEEECHHHCCCCHHHHHHHHHHHH
GERAIAVLGNHDLHLLAVAAGIRTLKPGDTIGEILDAPDADDLIEWVRHRPFAHFERGML
CHHHEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHCCEE
MVHAGLLPQWDAALALELADELQRALRAPNWRDTLRSLYGNDPNCWSPDLKHADRLRVAF
EEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
NAFTRIRFCTPEGAMEFRANGGPAAAPAGYLPWFDAPGRKTSDVTVVFGHWAALGLMLRE
HHHHEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHH
NLVALDSGCVWGNRLSAVRLADDPAARVVTQVACERCGAADE
HHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TNFSSSPPIAFGDLQGCHAAYRQLFDTLAPAADTPLWFAGDLVNRGPASLATLREIVAL
CCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCEEECHHHCCCCHHHHHHHHHHHH
GERAIAVLGNHDLHLLAVAAGIRTLKPGDTIGEILDAPDADDLIEWVRHRPFAHFERGML
CHHHEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHCCCHHHHHCCEE
MVHAGLLPQWDAALALELADELQRALRAPNWRDTLRSLYGNDPNCWSPDLKHADRLRVAF
EEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
NAFTRIRFCTPEGAMEFRANGGPAAAPAGYLPWFDAPGRKTSDVTVVFGHWAALGLMLRE
HHHHEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHH
NLVALDSGCVWGNRLSAVRLADDPAARVVTQVACERCGAADE
HHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA