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The map label for this gene is ribH

Identifier: 237813432

GI number: 237813432

Start: 3101909

End: 3102430

Strand: Direct

Name: ribH

Synonym: GBP346_A3207

Alternate gene names: 237813432

Gene position: 3101909-3102430 (Clockwise)

Preceding gene: 237813431

Following gene: 237813433

Centisome position: 75.68

GC content: 63.98

Gene sequence:

>522_bases
ATGGAAATCGGACAATATCAACCGAACCTCGAAGGCGACGGCCTGCGTATCGGCATCGTTCAATCGCGCTTCAACGAGCC
CGTGTGCAACGGCCTCGCGGATGCATGCGTCGAAGAGCTGGAGCGTCTCGGCGTCTCCGGCGAGGACGTGCTGCTCGTGA
CCGTGCCGGGCGCGCTCGAAATCCCGCTCGCGCTGCAAAAGCTCGCGGAGAGCAACCAGTTCGACGCGCTGATCGCGCTC
GGCGCGGTGATCCGCGGCGAGACGTATCACTTCGAACTCGTGTCGAACGAGAGCGGTGCGGGCATCACGCGCATCGCGCT
CGATTTCAACACGCCGATCGCGAACGCCGTGCTCACCACCGAGACCGACGAACAGGCGATCGCACGGATGACCGAAAAGG
GCCGCGACGCCGCGCGCGTGGCCGTCGAGATGGCGAACCTCACGATGACGCTCGATCAGTTGAGCGACGACGAAGAGGAC
GAGGAAGACGAGGACGACGAAGACGAAGAGGAGCGCGCATGA

Upstream 100 bases:

>100_bases
TCCGCGTCCGGCGCCGCATAACGGGTTTCGCGTCATCGCCACACTGTTGTCAGCCTGTGCTGCAGCCCCTATCACCGCCC
ATTCACTCTACGGAAAGAAT

Downstream 100 bases:

>100_bases
AGAAGAGCGCCCGCCGACAATCGCGCGAGCTGGCGACGCAGGGCCTGTATCAGTGGCTGCTGTCGAACGCGGCGCCGGGC
GAGATCGACGCGCAATTGCG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MEIGQYQPNLEGDGLRIGIVQSRFNEPVCNGLADACVEELERLGVSGEDVLLVTVPGALEIPLALQKLAESNQFDALIAL
GAVIRGETYHFELVSNESGAGITRIALDFNTPIANAVLTTETDEQAIARMTEKGRDAARVAVEMANLTMTLDQLSDDEED
EEDEDDEDEEERA

Sequences:

>Translated_173_residues
MEIGQYQPNLEGDGLRIGIVQSRFNEPVCNGLADACVEELERLGVSGEDVLLVTVPGALEIPLALQKLAESNQFDALIAL
GAVIRGETYHFELVSNESGAGITRIALDFNTPIANAVLTTETDEQAIARMTEKGRDAARVAVEMANLTMTLDQLSDDEED
EEDEDDEDEEERA
>Mature_173_residues
MEIGQYQPNLEGDGLRIGIVQSRFNEPVCNGLADACVEELERLGVSGEDVLLVTVPGALEIPLALQKLAESNQFDALIAL
GAVIRGETYHFELVSNESGAGITRIALDFNTPIANAVLTTETDEQAIARMTEKGRDAARVAVEMANLTMTLDQLSDDEED
EEDEDDEDEEERA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=137, Percent_Identity=43.7956204379562, Blast_Score=107, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6324429, Length=148, Percent_Identity=29.7297297297297, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_BURM7 (A3MMR3)

Other databases:

- EMBL:   CP000548
- RefSeq:   YP_001081549.1
- ProteinModelPortal:   A3MMR3
- SMR:   A3MMR3
- GeneID:   4893982
- GenomeReviews:   CP000548_GR
- KEGG:   bmn:BMA10247_2017
- TIGR:   BMA10247_2017
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- ProtClustDB:   PRK00061
- BioCyc:   BMAL320389:BMA10247_2017-MONOMER
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 18810; Mature: 18810

Theoretical pI: Translated: 3.68; Mature: 3.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIGQYQPNLEGDGLRIGIVQSRFNEPVCNGLADACVEELERLGVSGEDVLLVTVPGALE
CCCCCCCCCCCCCCEEEEEEHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
IPLALQKLAESNQFDALIALGAVIRGETYHFELVSNESGAGITRIALDFNTPIANAVLTT
HHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCCCCCEEEEC
ETDEQAIARMTEKGRDAARVAVEMANLTMTLDQLSDDEEDEEDEDDEDEEERA
CCHHHHHHHHHHCCCHHHHHHHHHHHHEEEHHHCCCCCCCCCCCCCCCHHHCC
>Mature Secondary Structure
MEIGQYQPNLEGDGLRIGIVQSRFNEPVCNGLADACVEELERLGVSGEDVLLVTVPGALE
CCCCCCCCCCCCCCEEEEEEHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
IPLALQKLAESNQFDALIALGAVIRGETYHFELVSNESGAGITRIALDFNTPIANAVLTT
HHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEEEECCCCCCCEEEEC
ETDEQAIARMTEKGRDAARVAVEMANLTMTLDQLSDDEEDEEDEDDEDEEERA
CCHHHHHHHHHHCCCHHHHHHHHHHHHEEEHHHCCCCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA