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The map label for this gene is ribBA [H]

Identifier: 237813431

GI number: 237813431

Start: 3100693

End: 3101829

Strand: Direct

Name: ribBA [H]

Synonym: GBP346_A3206

Alternate gene names: 237813431

Gene position: 3100693-3101829 (Clockwise)

Preceding gene: 237813430

Following gene: 237813432

Centisome position: 75.65

GC content: 67.9

Gene sequence:

>1137_bases
ATGACGCTCGCCTCCACGCCCGACATCATTGCCGAGCTCAAAGCCGGCCGGATGGTGATCCTGGTCGACGAAGAAGACCG
CGAAAACGAGGGCGATCTCGTGCTCGCCGCCGAATTCGTCACGCCGGAAGCGATCAACTTCATGGCCCGCTACGGCCGCG
GCCTGATCTGCCTCACGCTCACGCAGGAGCGCTGCAAGCAGCTCAACCTGCCGCTGATGACGTATCGCAACGGCACCCAG
TACGGCACCGCGTTCACGGTCAGCATCGAGGCGGCCGAGGGCGTGACGACAGGCATCTCGGCCGCGGACCGCGCGCGCAC
GATCGCAACGGCGGTCGCGCACGACGTGCGCCCCGAGCACATCGTGCAGCCGGGCCACGTGTTCCCGATCATGGCGCAGC
CGGGCGGCGTGCTCGTGCGCGCCGGTCACACCGAGGCGGGCTGCGATCTGACGGCGCTCGCGGGCCTCACGCCCGCCGCC
GTGATCTGCGAGATCATCAAGGACGACGGCACGATGGCGCGCCTGCCGGATCTGCTCGAATTCGGCAAGGAGCACGGCCT
GAAGATCGGCACGATCGCCGATCTGATCCACTACCGCAGCCGCACCGAGTCGATCGTCGAGCGCGTCGCCGAGCGCACGA
TGCAAACCGCGCACGGCCCGTTCAAGACGGTGCTGTACCGCGATCACCCCACGGGCTCGCCGCACATCGCGCTCGTGCGC
GGCACACCCACGCCGAACGACGAGACGCCCGTGCGCGTGCACGAGCCGCTGTCCGTGCTCGATCTGCTCGAAACCGGCGT
GTCGACGCACTCGTGGACGCTCGACGCCGCGATGAAGGAAATCGCGGCGCGCGAACTCGGCGTGATCGTGCTCCTGAATT
GCGGCGACACGAAGGAGCATCTCGTCGACGTGTTCCTCGCGTTCGACGAGAAGGAGAAGGCAGCCGAGCTCAAGCGCCGG
CCGGTCGATTTCAAGACGTTCGGCATCGGCGCGCAGATCCTGCGCGACGTCGGCGTCGGCAGGATGCAGGTGCTGTCGAA
TCCGCGCAAGCTCGGCAGCATGTCGGGCTACGGCCTCGAAGTCACCGGCTTCGCGCCGATGCCGGGAAGCGCGACATCCG
CGTCCGGCGCCGCATAA

Upstream 100 bases:

>100_bases
TCGGCCGTCCGGCCAACGCGGCGGCCCGCCGCGCCGCGTCCGGCGAAAACCCGCCGCGCGTGGCGTAAAATACGCGCTTT
CCCTTCCCCCTGATCCTTTT

Downstream 100 bases:

>100_bases
CGGGTTTCGCGTCATCGCCACACTGTTGTCAGCCTGTGCTGCAGCCCCTATCACCGCCCATTCACTCTACGGAAAGAATA
TGGAAATCGGACAATATCAA

Product: bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVLAAEFVTPEAINFMARYGRGLICLTLTQERCKQLNLPLMTYRNGTQ
YGTAFTVSIEAAEGVTTGISAADRARTIATAVAHDVRPEHIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAA
VICEIIKDDGTMARLPDLLEFGKEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGPFKTVLYRDHPTGSPHIALVR
GTPTPNDETPVRVHEPLSVLDLLETGVSTHSWTLDAAMKEIAARELGVIVLLNCGDTKEHLVDVFLAFDEKEKAAELKRR
PVDFKTFGIGAQILRDVGVGRMQVLSNPRKLGSMSGYGLEVTGFAPMPGSATSASGAA

Sequences:

>Translated_378_residues
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVLAAEFVTPEAINFMARYGRGLICLTLTQERCKQLNLPLMTYRNGTQ
YGTAFTVSIEAAEGVTTGISAADRARTIATAVAHDVRPEHIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAA
VICEIIKDDGTMARLPDLLEFGKEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGPFKTVLYRDHPTGSPHIALVR
GTPTPNDETPVRVHEPLSVLDLLETGVSTHSWTLDAAMKEIAARELGVIVLLNCGDTKEHLVDVFLAFDEKEKAAELKRR
PVDFKTFGIGAQILRDVGVGRMQVLSNPRKLGSMSGYGLEVTGFAPMPGSATSASGAA
>Mature_377_residues
TLASTPDIIAELKAGRMVILVDEEDRENEGDLVLAAEFVTPEAINFMARYGRGLICLTLTQERCKQLNLPLMTYRNGTQY
GTAFTVSIEAAEGVTTGISAADRARTIATAVAHDVRPEHIVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAV
ICEIIKDDGTMARLPDLLEFGKEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGPFKTVLYRDHPTGSPHIALVRG
TPTPNDETPVRVHEPLSVLDLLETGVSTHSWTLDAAMKEIAARELGVIVLLNCGDTKEHLVDVFLAFDEKEKAAELKRRP
VDFKTFGIGAQILRDVGVGRMQVLSNPRKLGSMSGYGLEVTGFAPMPGSATSASGAA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=196, Percent_Identity=52.5510204081633, Blast_Score=221, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6320695, Length=202, Percent_Identity=42.5742574257426, Blast_Score=166, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40652; Mature: 40521

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLASTPDIIAELKAGRMVILVDEEDRENEGDLVLAAEFVTPEAINFMARYGRGLICLTL
CCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE
TQERCKQLNLPLMTYRNGTQYGTAFTVSIEAAEGVTTGISAADRARTIATAVAHDVRPEH
CHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
IVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAVICEIIKDDGTMARLPDLLE
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
FGKEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGPFKTVLYRDHPTGSPHIALVR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEE
GTPTPNDETPVRVHEPLSVLDLLETGVSTHSWTLDAAMKEIAARELGVIVLLNCGDTKEH
CCCCCCCCCCEEEECCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCEEEEEECCCCHHH
LVDVFLAFDEKEKAAELKRRPVDFKTFGIGAQILRDVGVGRMQVLSNPRKLGSMSGYGLE
HHHHHHHCCCHHHHHHHHHCCCCEEEECCHHHHHHHCCCCHHHHHCCCHHHCCCCCCCEE
VTGFAPMPGSATSASGAA
EEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLASTPDIIAELKAGRMVILVDEEDRENEGDLVLAAEFVTPEAINFMARYGRGLICLTL
CCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEE
TQERCKQLNLPLMTYRNGTQYGTAFTVSIEAAEGVTTGISAADRARTIATAVAHDVRPEH
CHHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHH
IVQPGHVFPIMAQPGGVLVRAGHTEAGCDLTALAGLTPAAVICEIIKDDGTMARLPDLLE
CCCCCCEEEEEECCCCEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHH
FGKEHGLKIGTIADLIHYRSRTESIVERVAERTMQTAHGPFKTVLYRDHPTGSPHIALVR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEE
GTPTPNDETPVRVHEPLSVLDLLETGVSTHSWTLDAAMKEIAARELGVIVLLNCGDTKEH
CCCCCCCCCCEEEECCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCEEEEEECCCCHHH
LVDVFLAFDEKEKAAELKRRPVDFKTFGIGAQILRDVGVGRMQVLSNPRKLGSMSGYGLE
HHHHHHHCCCHHHHHHHHHCCCCEEEECCHHHHHHHCCCCHHHHHCCCHHHCCCCCCCEE
VTGFAPMPGSATSASGAA
EEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]