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The map label for this gene is add [H]

Identifier: 237813346

GI number: 237813346

Start: 3023859

End: 3024884

Strand: Direct

Name: add [H]

Synonym: GBP346_A3115

Alternate gene names: 237813346

Gene position: 3023859-3024884 (Clockwise)

Preceding gene: 237813345

Following gene: 237813347

Centisome position: 73.78

GC content: 66.47

Gene sequence:

>1026_bases
ATGACCCCGACATTCAAAGACAAGATCGCCCGTGCGCCGAAGGCCGAGCTGCACATCCACATCGAAGGCTCGCTCGAGCC
CGAGCTGATCTTCGAGCTCGCGCAGCGCAACGGCGTGAAGCTCGCGTACGAATCGATCGACGCGCTGCGCGCCGCGTACG
CGTTCACCGATCTGCAGTCGTTCCTCGACATCTATTACGCCGGCGCGAGCGTGCTCCTCACCGAGCAGGATTTCTACGAC
ATGACGGCCGCATACGTCGAGCGCGCGCTCGCCGATCACGTCGTGCACGCGGAGATCTTCTTCGATCCGCAGACGCACAC
CGAGCGCGGCGTGCCGATCGAGACGGTCGTCGCCGGCATCGATCGCGCGCTCGCCGACGCGGAAAAACGCGGCTTCTCGA
GCAAGCTGATCCTCTGCTTCCTGCGCCACCTGTCCGAGGAAAGCGCGCTCGCGACGTTCGACGCGGCGCTGCCGCTCTTC
GATCGCTATGCGCGGCGCCTGATCGGCGTGGGGCTCGATTCGTCCGAGCGCGGCAATCCGCCGTCGAAGTTCGCGCGCGT
GTTCGCGAAGGCGCGAGAGCGGGGCCTGAAGCTCGTCGCGCACGCGGGCGAGGAAGGCCCGCCCGAATACGTGACGCAGG
CGCTCGACGTGCTGAAGATCGACCGCGTCGATCACGGCGTGCGCAGCGCCGAGGACGCGGCGCTCGTCGCGCGCCTTGCC
GGCGAGAAGATCGCGCTCACCGTCTGCCCGCTGTCGAACCTGAAGCTCTGCGTGTTCGACGACCTGACGAAGCACACGCT
GAAGACGCTGCTCGATCGCGGCATCGCGGTGACGATCAATTCCGACGACCCGGCGTATTTCGGCGGCTACGTCAACGAAA
ACTACTTCGCGACCGTCGACGCGCTGCAGCTTGGCGAGGCCGACGTCTACACGGTGATCAGGAACGGCTTCGAAGCGTCG
TTCGTGAGCGCCGACGAACGCGCGGCGCTGATCGCGAAGCTCGACGCGCACTGGCACGCGGCCTGA

Upstream 100 bases:

>100_bases
TCGACGCGCGGCGCGCGAACGGGCGTCCGGCCGCGCCGCCCGGCGCGAGCGCGTGCTGAATCGCCGCCATCCAAACCCGC
ATTCGACCCAAAAAACCACA

Downstream 100 bases:

>100_bases
CGGCCGCGCAACGCGCGCGCCCCGCATGCGGCGGCGCGCGAAGCGCGCGCGTTGCGACGCGTTGCGCTCGACACGAGACA
CTGAGGAGAGCTTAACGATG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTPTFKDKIARAPKAELHIHIEGSLEPELIFELAQRNGVKLAYESIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYD
MTAAYVERALADHVVHAEIFFDPQTHTERGVPIETVVAGIDRALADAEKRGFSSKLILCFLRHLSEESALATFDAALPLF
DRYARRLIGVGLDSSERGNPPSKFARVFAKARERGLKLVAHAGEEGPPEYVTQALDVLKIDRVDHGVRSAEDAALVARLA
GEKIALTVCPLSNLKLCVFDDLTKHTLKTLLDRGIAVTINSDDPAYFGGYVNENYFATVDALQLGEADVYTVIRNGFEAS
FVSADERAALIAKLDAHWHAA

Sequences:

>Translated_341_residues
MTPTFKDKIARAPKAELHIHIEGSLEPELIFELAQRNGVKLAYESIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYD
MTAAYVERALADHVVHAEIFFDPQTHTERGVPIETVVAGIDRALADAEKRGFSSKLILCFLRHLSEESALATFDAALPLF
DRYARRLIGVGLDSSERGNPPSKFARVFAKARERGLKLVAHAGEEGPPEYVTQALDVLKIDRVDHGVRSAEDAALVARLA
GEKIALTVCPLSNLKLCVFDDLTKHTLKTLLDRGIAVTINSDDPAYFGGYVNENYFATVDALQLGEADVYTVIRNGFEAS
FVSADERAALIAKLDAHWHAA
>Mature_340_residues
TPTFKDKIARAPKAELHIHIEGSLEPELIFELAQRNGVKLAYESIDALRAAYAFTDLQSFLDIYYAGASVLLTEQDFYDM
TAAYVERALADHVVHAEIFFDPQTHTERGVPIETVVAGIDRALADAEKRGFSSKLILCFLRHLSEESALATFDAALPLFD
RYARRLIGVGLDSSERGNPPSKFARVFAKARERGLKLVAHAGEEGPPEYVTQALDVLKIDRVDHGVRSAEDAALVARLAG
EKIALTVCPLSNLKLCVFDDLTKHTLKTLLDRGIAVTINSDDPAYFGGYVNENYFATVDALQLGEADVYTVIRNGFEASF
VSADERAALIAKLDAHWHAA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=352, Percent_Identity=26.9886363636364, Blast_Score=116, Evalue=3e-26,
Organism=Escherichia coli, GI1787910, Length=330, Percent_Identity=30.3030303030303, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32565969, Length=342, Percent_Identity=22.8070175438596, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538512, Length=342, Percent_Identity=22.8070175438596, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324188, Length=335, Percent_Identity=41.4925373134328, Blast_Score=274, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24645260, Length=329, Percent_Identity=23.4042553191489, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37514; Mature: 37383

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTFKDKIARAPKAELHIHIEGSLEPELIFELAQRNGVKLAYESIDALRAAYAFTDLQS
CCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHH
FLDIYYAGASVLLTEQDFYDMTAAYVERALADHVVHAEIFFDPQTHTERGVPIETVVAGI
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHH
DRALADAEKRGFSSKLILCFLRHLSEESALATFDAALPLFDRYARRLIGVGLDSSERGNP
HHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSKFARVFAKARERGLKLVAHAGEEGPPEYVTQALDVLKIDRVDHGVRSAEDAALVARLA
HHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
GEKIALTVCPLSNLKLCVFDDLTKHTLKTLLDRGIAVTINSDDPAYFGGYVNENYFATVD
CCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEEEH
ALQLGEADVYTVIRNGFEASFVSADERAALIAKLDAHWHAA
HHHCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TPTFKDKIARAPKAELHIHIEGSLEPELIFELAQRNGVKLAYESIDALRAAYAFTDLQS
CCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHH
FLDIYYAGASVLLTEQDFYDMTAAYVERALADHVVHAEIFFDPQTHTERGVPIETVVAGI
HHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHH
DRALADAEKRGFSSKLILCFLRHLSEESALATFDAALPLFDRYARRLIGVGLDSSERGNP
HHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSKFARVFAKARERGLKLVAHAGEEGPPEYVTQALDVLKIDRVDHGVRSAEDAALVARLA
HHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHC
GEKIALTVCPLSNLKLCVFDDLTKHTLKTLLDRGIAVTINSDDPAYFGGYVNENYFATVD
CCEEEEEEECCCCCEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCEEEEEH
ALQLGEADVYTVIRNGFEASFVSADERAALIAKLDAHWHAA
HHHCCCHHHHHHHHCCCCHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA