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The map label for this gene is aidB [H]

Identifier: 237813068

GI number: 237813068

Start: 2764797

End: 2766584

Strand: Reverse

Name: aidB [H]

Synonym: GBP346_A2829

Alternate gene names: 237813068

Gene position: 2766584-2764797 (Counterclockwise)

Preceding gene: 237813070

Following gene: 237813067

Centisome position: 67.5

GC content: 70.41

Gene sequence:

>1788_bases
ATGAACATGATGAAGGAAACCGTCGAAGCAAACGCGCCCGCGGCGGGCGCAGCCAACATCCCCGATTCGCGGGGCATCAA
TTTCTTCACGAGCGATCCCGATTGCGCGGCGTTGCTGCGGCTCCATCTGGGCGAAGCGCGCTTTCGCGGCTTCGAGCCGG
AACTGCGCGCGCTCGGGCTGCGCGCGTCGGACGAGCTCGACCGCCTCGCGTCGCGCGCCGACAGGAACCCGCCCGTGCTT
CAGCCGCGCACGCGGCGCGGCGAGCCGCTCGAGTCGATCGACAAGCATCCGGACTACGTCGAGCTCGAGCGCGTCGCATA
TGCGCAGCTCGGGCTCGCCGCGATGAGCCATCGCGACGGCGCGCCGCCGCCGCTCGTCAAATACGCGTTGACGTTCCTGT
TCGTGCAGGCCGAGTTCGGCCTTTGCTGCCCCGTCAGCATGACCGATTCGCTCACGCGTACGCTGCGCCGCTTCGGTTCG
CGCGAGCTCGTCGAGCGTTTCCTGCCGCGGCTCGCGTCGCGCGATTTCGACGTGCTGTATCAGGGCGCGATGTTCATGAC
CGAGCAGGCGGCGGGCTCCGACGTCGGCCGCATCGCGACGCGTGCGGTGCGCGGCACGTCCGCCGACGGTTCGGCGACAT
GGCGGCTGTTCGGCGACAAGTGGTTCTGCTCGAACGCGGACGCCGATCTTGCGATGGTGCTCGCCCGGCCCGAAGGCGCG
CCCGACGGCGTGAAGGGCCTCGCGCTGTTCCTGCTGCCGAAGACGCTCGCCGACGGCTCGCGCAATCGCTATCGGATCGT
ACGCCTGAAGGACAAGCTCGGCAGCCGTTCGATGGCGAGCGGCGAGATCGCGCTCGACGGCGCCGAAGCCTATCTGATCG
GCGAGATCGGCCGCGGCTTTCATCAGATGGCCGACATGATCAACATGTCGCGTCTGTCGAACGGCGTGCGCGCAGCGGGG
CTGATGCGGCGCGCGACGACGGAGGCGCTGCACGTCGCGCGCCATCGCGAAGCGTTCGGCCGCAAGCTGATCGACATGCC
GCTGATGCAGCGGCAACTCGTCAAGATGCTCGTGCCGACCGAGCAGGCGCGCTCGCTGTTCATGCAGATCGCGCTGCTGC
TCGCGAAGGCGGACGCGGGCGACGCGCAGGCAGGCGGCTGCGTGCGGATCCTGACGCCGCTCGTCAAGTTCCGCGCGTGC
CGCGATGCGCGCCGCGTTGCCGGCGATGCGATGGAGGTGCGCGGCGGCACCGGCTACATCGAGGAGTGGAGCGATGCGCG
CGTGCTGCGCGATGCACATCTCGGCTCGATCTGGGAGGGCACGAGCAACATCGTCGCGCTCGACGTCGCGCGGGCGGTCA
AGCGCGAAGGGGCGCTCGCGCCGCTGCGCGCGTTCCTGCTCGGCGCGCTCGACACGGCGCGGCTGCCGGGCGCGAGCGCC
ACGCGGCTGCGCCGCGCGCTCGATCGCGCGAGCGATGCGATCGCGCACGTCGCGCGAACGGGCGACGATGCGTTCGTGCG
GCAGGCGGCGTCCGCGCTCTATCACGCGACGACGGCGATCCTGCTCGCGAGCGAAGGGATGCGGCTCGCGCCCGATCATC
GGCGGCTCGCGCTCGCTCATCTCGTGTTGCGCTACAAGCTGTCGCCCGTCGATCCGCTCGCGACGCCGCGCGCCGATGCC
GACGCGGACGCGGAGGCCGGCGTGCTGGCGGCGTTGTTGCACGATCGGCCCGTCACGCTCGACGACGCGTTGCGCCTGCT
CGACGATGGTTCGGGAGACGCGGCATGA

Upstream 100 bases:

>100_bases
CATTCTGGCAATCGATAAATAGCGTTTATCGTACTGGATAAATCCTGTATTGGACGATTATCGATCGCGGTTCTACGCTC
GTCGGACCAGGAGACAAGCG

Downstream 100 bases:

>100_bases
GCGGCAATGTCTCGAAGCGATTGCGGGCCTCGAGCGGATCGGAGATCGGGCGCGCCGCCGCCGGTGCGAGCGATGCGGCA
GGGGCGGCCGGCACCGCCGG

Product: acyl-CoA dehydrogenase domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MNMMKETVEANAPAAGAANIPDSRGINFFTSDPDCAALLRLHLGEARFRGFEPELRALGLRASDELDRLASRADRNPPVL
QPRTRRGEPLESIDKHPDYVELERVAYAQLGLAAMSHRDGAPPPLVKYALTFLFVQAEFGLCCPVSMTDSLTRTLRRFGS
RELVERFLPRLASRDFDVLYQGAMFMTEQAAGSDVGRIATRAVRGTSADGSATWRLFGDKWFCSNADADLAMVLARPEGA
PDGVKGLALFLLPKTLADGSRNRYRIVRLKDKLGSRSMASGEIALDGAEAYLIGEIGRGFHQMADMINMSRLSNGVRAAG
LMRRATTEALHVARHREAFGRKLIDMPLMQRQLVKMLVPTEQARSLFMQIALLLAKADAGDAQAGGCVRILTPLVKFRAC
RDARRVAGDAMEVRGGTGYIEEWSDARVLRDAHLGSIWEGTSNIVALDVARAVKREGALAPLRAFLLGALDTARLPGASA
TRLRRALDRASDAIAHVARTGDDAFVRQAASALYHATTAILLASEGMRLAPDHRRLALAHLVLRYKLSPVDPLATPRADA
DADAEAGVLAALLHDRPVTLDDALRLLDDGSGDAA

Sequences:

>Translated_595_residues
MNMMKETVEANAPAAGAANIPDSRGINFFTSDPDCAALLRLHLGEARFRGFEPELRALGLRASDELDRLASRADRNPPVL
QPRTRRGEPLESIDKHPDYVELERVAYAQLGLAAMSHRDGAPPPLVKYALTFLFVQAEFGLCCPVSMTDSLTRTLRRFGS
RELVERFLPRLASRDFDVLYQGAMFMTEQAAGSDVGRIATRAVRGTSADGSATWRLFGDKWFCSNADADLAMVLARPEGA
PDGVKGLALFLLPKTLADGSRNRYRIVRLKDKLGSRSMASGEIALDGAEAYLIGEIGRGFHQMADMINMSRLSNGVRAAG
LMRRATTEALHVARHREAFGRKLIDMPLMQRQLVKMLVPTEQARSLFMQIALLLAKADAGDAQAGGCVRILTPLVKFRAC
RDARRVAGDAMEVRGGTGYIEEWSDARVLRDAHLGSIWEGTSNIVALDVARAVKREGALAPLRAFLLGALDTARLPGASA
TRLRRALDRASDAIAHVARTGDDAFVRQAASALYHATTAILLASEGMRLAPDHRRLALAHLVLRYKLSPVDPLATPRADA
DADAEAGVLAALLHDRPVTLDDALRLLDDGSGDAA
>Mature_595_residues
MNMMKETVEANAPAAGAANIPDSRGINFFTSDPDCAALLRLHLGEARFRGFEPELRALGLRASDELDRLASRADRNPPVL
QPRTRRGEPLESIDKHPDYVELERVAYAQLGLAAMSHRDGAPPPLVKYALTFLFVQAEFGLCCPVSMTDSLTRTLRRFGS
RELVERFLPRLASRDFDVLYQGAMFMTEQAAGSDVGRIATRAVRGTSADGSATWRLFGDKWFCSNADADLAMVLARPEGA
PDGVKGLALFLLPKTLADGSRNRYRIVRLKDKLGSRSMASGEIALDGAEAYLIGEIGRGFHQMADMINMSRLSNGVRAAG
LMRRATTEALHVARHREAFGRKLIDMPLMQRQLVKMLVPTEQARSLFMQIALLLAKADAGDAQAGGCVRILTPLVKFRAC
RDARRVAGDAMEVRGGTGYIEEWSDARVLRDAHLGSIWEGTSNIVALDVARAVKREGALAPLRAFLLGALDTARLPGASA
TRLRRALDRASDAIAHVARTGDDAFVRQAASALYHATTAILLASEGMRLAPDHRRLALAHLVLRYKLSPVDPLATPRADA
DADAEAGVLAALLHDRPVTLDDALRLLDDGSGDAA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=327, Percent_Identity=26.9113149847095, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI226958412, Length=312, Percent_Identity=27.5641025641026, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI226958414, Length=310, Percent_Identity=27.741935483871, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI21361497, Length=342, Percent_Identity=26.0233918128655, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI4557233, Length=318, Percent_Identity=27.6729559748428, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4557235, Length=301, Percent_Identity=27.2425249169435, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI76496475, Length=301, Percent_Identity=27.2425249169435, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4501857, Length=304, Percent_Identity=27.3026315789474, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4557231, Length=298, Percent_Identity=26.8456375838926, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI187960098, Length=298, Percent_Identity=26.8456375838926, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4503943, Length=308, Percent_Identity=29.5454545454545, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI87082384, Length=416, Percent_Identity=34.8557692307692, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI87081958, Length=308, Percent_Identity=27.9220779220779, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1786223, Length=275, Percent_Identity=25.4545454545455, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86563381, Length=439, Percent_Identity=33.2574031890661, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI86563383, Length=439, Percent_Identity=33.2574031890661, Blast_Score=213, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17538396, Length=304, Percent_Identity=29.9342105263158, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17508101, Length=304, Percent_Identity=26.3157894736842, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17506239, Length=317, Percent_Identity=26.1829652996845, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17551932, Length=306, Percent_Identity=30.718954248366, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=316, Percent_Identity=29.4303797468354, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=293, Percent_Identity=25.938566552901, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17534353, Length=308, Percent_Identity=26.9480519480519, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17533517, Length=311, Percent_Identity=24.4372990353698, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=216, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17570075, Length=296, Percent_Identity=25.6756756756757, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=303, Percent_Identity=25.0825082508251, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17569725, Length=301, Percent_Identity=25.9136212624585, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=210, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982178, Length=198, Percent_Identity=28.2828282828283, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666513, Length=321, Percent_Identity=25.8566978193146, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355753, Length=308, Percent_Identity=28.2467532467532, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281363737, Length=442, Percent_Identity=25.5656108597285, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24660351, Length=302, Percent_Identity=27.4834437086093, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356377, Length=281, Percent_Identity=25.9786476868327, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646207, Length=303, Percent_Identity=26.0726072607261, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 64572; Mature: 64572

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMMKETVEANAPAAGAANIPDSRGINFFTSDPDCAALLRLHLGEARFRGFEPELRALGL
CCHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHCC
RASDELDRLASRADRNPPVLQPRTRRGEPLESIDKHPDYVELERVAYAQLGLAAMSHRDG
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
APPPLVKYALTFLFVQAEFGLCCPVSMTDSLTRTLRRFGSRELVERFLPRLASRDFDVLY
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
QGAMFMTEQAAGSDVGRIATRAVRGTSADGSATWRLFGDKWFCSNADADLAMVLARPEGA
HCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCCCCCEEEEEECCCCC
PDGVKGLALFLLPKTLADGSRNRYRIVRLKDKLGSRSMASGEIALDGAEAYLIGEIGRGF
CCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCCEEECCCCEEEEHHHHHHH
HQMADMINMSRLSNGVRAAGLMRRATTEALHVARHREAFGRKLIDMPLMQRQLVKMLVPT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EQARSLFMQIALLLAKADAGDAQAGGCVRILTPLVKFRACRDARRVAGDAMEVRGGTGYI
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCH
EEWSDARVLRDAHLGSIWEGTSNIVALDVARAVKREGALAPLRAFLLGALDTARLPGASA
HCCCCHHHHHHHHCCCHHCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHH
TRLRRALDRASDAIAHVARTGDDAFVRQAASALYHATTAILLASEGMRLAPDHRRLALAH
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LVLRYKLSPVDPLATPRADADADAEAGVLAALLHDRPVTLDDALRLLDDGSGDAA
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNMMKETVEANAPAAGAANIPDSRGINFFTSDPDCAALLRLHLGEARFRGFEPELRALGL
CCHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHCC
RASDELDRLASRADRNPPVLQPRTRRGEPLESIDKHPDYVELERVAYAQLGLAAMSHRDG
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
APPPLVKYALTFLFVQAEFGLCCPVSMTDSLTRTLRRFGSRELVERFLPRLASRDFDVLY
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHH
QGAMFMTEQAAGSDVGRIATRAVRGTSADGSATWRLFGDKWFCSNADADLAMVLARPEGA
HCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCCCCCEEEEEECCCCC
PDGVKGLALFLLPKTLADGSRNRYRIVRLKDKLGSRSMASGEIALDGAEAYLIGEIGRGF
CCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHCCCCCCCCCCEEECCCCEEEEHHHHHHH
HQMADMINMSRLSNGVRAAGLMRRATTEALHVARHREAFGRKLIDMPLMQRQLVKMLVPT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EQARSLFMQIALLLAKADAGDAQAGGCVRILTPLVKFRACRDARRVAGDAMEVRGGTGYI
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCH
EEWSDARVLRDAHLGSIWEGTSNIVALDVARAVKREGALAPLRAFLLGALDTARLPGASA
HCCCCHHHHHHHHCCCHHCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHH
TRLRRALDRASDAIAHVARTGDDAFVRQAASALYHATTAILLASEGMRLAPDHRRLALAH
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LVLRYKLSPVDPLATPRADADADAEAGVLAALLHDRPVTLDDALRLLDDGSGDAA
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]